JP2009524428A5 - - Google Patents

Download PDF

Info

Publication number
JP2009524428A5
JP2009524428A5 JP2008552351A JP2008552351A JP2009524428A5 JP 2009524428 A5 JP2009524428 A5 JP 2009524428A5 JP 2008552351 A JP2008552351 A JP 2008552351A JP 2008552351 A JP2008552351 A JP 2008552351A JP 2009524428 A5 JP2009524428 A5 JP 2009524428A5
Authority
JP
Japan
Prior art keywords
seq
amino acids
cdr
binding protein
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2008552351A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009524428A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/001687 external-priority patent/WO2007089470A2/en
Publication of JP2009524428A publication Critical patent/JP2009524428A/ja
Publication of JP2009524428A5 publication Critical patent/JP2009524428A5/ja
Withdrawn legal-status Critical Current

Links

JP2008552351A 2006-01-27 2007-01-23 スタヒロコッカス・アウレウスorf0657nを標的とする抗原結合タンパク質 Withdrawn JP2009524428A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76302306P 2006-01-27 2006-01-27
PCT/US2007/001687 WO2007089470A2 (en) 2006-01-27 2007-01-23 Antigen-binding proteins targeting s. aureus orf0657n

Publications (2)

Publication Number Publication Date
JP2009524428A JP2009524428A (ja) 2009-07-02
JP2009524428A5 true JP2009524428A5 (https=) 2010-03-11

Family

ID=38327867

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008552351A Withdrawn JP2009524428A (ja) 2006-01-27 2007-01-23 スタヒロコッカス・アウレウスorf0657nを標的とする抗原結合タンパク質

Country Status (7)

Country Link
US (1) US20110091480A1 (https=)
EP (1) EP1982185A4 (https=)
JP (1) JP2009524428A (https=)
CN (1) CN101375161A (https=)
AU (1) AU2007210170A1 (https=)
CA (1) CA2637152A1 (https=)
WO (1) WO2007089470A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0811193A2 (pt) * 2007-05-31 2014-11-11 Merck & Co Inc Proteína de ligação a antígeno isolada, ácido nucleico, célula recombinante, métodos para produzir uma proteína e para proteger ou tratar contra uma infecção por s. aureus em paciente, composição farmacêutica, uso da proteína de ligação a antígeno, e, polipeptídeo.
EP2185190B1 (en) 2007-08-31 2015-06-24 University Of Chicago Methods and compositions related to immunizing against staphylococcal lung diseases and conditions
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
WO2010014304A1 (en) 2008-07-29 2010-02-04 University Of Chicago Compositions and methods related to staphylococcal bacterium proteins
ES2784957T3 (es) 2009-04-03 2020-10-02 Univ Chicago Composiciones y métodos relacionados con variantes de la proteína A (SPA)
JP6002128B2 (ja) 2010-07-02 2016-10-05 ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago プロテインA(SpA)変種に関連する組成物および方法
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
MX2021013833A (es) 2019-05-14 2022-03-17 Univ Chicago Metodos y composiciones que comprenden variantes de la proteina a de estafilococos (spa).
WO2021051136A1 (en) 2019-09-13 2021-03-18 The University Of Chicago Methods and compositions for treating staphylococcal infections
WO2022042673A1 (zh) * 2020-08-28 2022-03-03 江苏恒瑞医药股份有限公司 用于降低异源多肽末端异质性的信号肽

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6916605B1 (en) * 1990-07-10 2005-07-12 Medical Research Council Methods for producing members of specific binding pairs
PT1377314E (pt) * 2001-01-26 2012-01-02 Inhibitex Inc Anticorpos monoclonais para a proteína clfa e método de utilização no tratamento ou prevenção de infecções
US20070275460A1 (en) * 2003-03-03 2007-11-29 Xencor.Inc. Fc Variants With Optimized Fc Receptor Binding Properties
ATE457737T1 (de) * 2003-07-24 2010-03-15 Merck & Co Inc Polypeptide zur induktion einer schützenden immunantwort gegen staphylococcus aureus
CN1980692A (zh) * 2003-07-24 2007-06-13 麦克公司 用于诱导针对金黄色葡萄球菌的保护性免疫反应的多肽
AU2006206577B2 (en) * 2005-01-21 2012-03-08 Merck Sharp & Dohme Corp. Polypeptides for inducing a protective immune response against Staphylococcus aureus
EP2117574A4 (en) * 2007-01-24 2010-06-16 Merck Sharp & Dohme POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS EPIDERMIDIS
EP2126070A4 (en) * 2007-03-19 2010-03-31 Merck Sharp & Dohme POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS EPIDERMIDIS
BRPI0811193A2 (pt) * 2007-05-31 2014-11-11 Merck & Co Inc Proteína de ligação a antígeno isolada, ácido nucleico, célula recombinante, métodos para produzir uma proteína e para proteger ou tratar contra uma infecção por s. aureus em paciente, composição farmacêutica, uso da proteína de ligação a antígeno, e, polipeptídeo.

Similar Documents

Publication Publication Date Title
JP2009524428A5 (https=)
TWI785583B (zh) 一種抗新型冠狀病毒的單克隆抗體及其應用
CN116063464B (zh) 冠状病毒的抗体或其抗原结合片段
RU2009149294A (ru) Антиген-связывающие белки, нацеленные на orf0657n s.aureus
US8298545B2 (en) Anti-autoimmune antibodies for treatment of pemphigus
CN111606993B (zh) 抗呼吸道合胞病毒的全人广谱中和抗体4f1及其应用
CN102906111B (zh) 特异性结合乙型肝炎病毒表面抗原的人抗体
CN115043938B (zh) SARS-CoV-2及其突变株的抗体及应用
JP2011509245A5 (https=)
CN114644708B (zh) 呼吸道合胞病毒特异性结合分子
CN109867723B (zh) 抗人il6单克隆抗体及其制备方法和用途
JP2017505635A (ja) 黄色ブドウ球菌特異的抗体、それを用いた治療方法及び検出方法
WO2020186687A1 (zh) 一种特异性结合四种血清型登革病毒的人源抗体
JP2005514053A5 (https=)
CN117603358A (zh) 一种广谱新型冠状病毒的双特异性抗体
US20240059764A1 (en) ANTIGEN-BINDING PROTEIN TARGETING STAPHYLOCOCCUS AUREUS a-HEMOLYSIS AND APPLICATION THEREOF
CN114805570B (zh) 一种抗人ace2单克隆抗体及其应用
US20230183322A1 (en) Method for preparing antigen-binding unit
JP2023535233A (ja) グリコシル化ceacam5に特異的に結合した抗体
CN114805579B (zh) 一种抗人ace2蛋白单克隆抗体、核酸分子及应用
CN118085082A (zh) 抗猫TNF-α单克隆抗体及其应用
CN117683123A (zh) 抗狂犬病毒人源化抗体和抗体组合及其用途
CN113549146B (zh) 针对柯萨奇病毒b1型的单克隆抗体及其用途
CN116606373A (zh) 新型冠状病毒中和抗体及其用途
CN107417788A (zh) 抗埃博拉病毒的中和性单克隆抗体