JP2009523411A5 - - Google Patents

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Publication number
JP2009523411A5
JP2009523411A5 JP2008545095A JP2008545095A JP2009523411A5 JP 2009523411 A5 JP2009523411 A5 JP 2009523411A5 JP 2008545095 A JP2008545095 A JP 2008545095A JP 2008545095 A JP2008545095 A JP 2008545095A JP 2009523411 A5 JP2009523411 A5 JP 2009523411A5
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JP
Japan
Prior art keywords
flg
mutation
repeat
gene
filaggrin
Prior art date
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Granted
Application number
JP2008545095A
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English (en)
Japanese (ja)
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JP2009523411A (ja
JP5305921B2 (ja
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Publication date
Priority claimed from GBGB0525492.5A external-priority patent/GB0525492D0/en
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Publication of JP2009523411A publication Critical patent/JP2009523411A/ja
Publication of JP2009523411A5 publication Critical patent/JP2009523411A5/ja
Application granted granted Critical
Publication of JP5305921B2 publication Critical patent/JP5305921B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008545095A 2005-12-15 2006-12-15 フィラグリン Expired - Fee Related JP5305921B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0525492.5A GB0525492D0 (en) 2005-12-15 2005-12-15 Filaggrin
GB0525492.5 2005-12-15
PCT/GB2006/004707 WO2007068946A2 (en) 2005-12-15 2006-12-15 Identification of loss-of-function mutations in filaggrin causing ichthyosis vulgaris and predisposing to other diseases

Publications (3)

Publication Number Publication Date
JP2009523411A JP2009523411A (ja) 2009-06-25
JP2009523411A5 true JP2009523411A5 (enExample) 2010-02-12
JP5305921B2 JP5305921B2 (ja) 2013-10-02

Family

ID=35736147

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008545095A Expired - Fee Related JP5305921B2 (ja) 2005-12-15 2006-12-15 フィラグリン

Country Status (5)

Country Link
US (1) US8999635B2 (enExample)
EP (1) EP1960539B1 (enExample)
JP (1) JP5305921B2 (enExample)
GB (2) GB0525492D0 (enExample)
WO (1) WO2007068946A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0600948D0 (en) 2006-01-18 2006-02-22 Univ Dundee Prevention/Treatment Of Ichthyosis Vulgaris, Atopy And Other Disorders
JP5451607B2 (ja) * 2007-06-28 2014-03-26 リバー ダイアグノスティックス ベー．フェー． 突然変異の可能性を判定する方法
EP2322656A1 (en) * 2009-11-17 2011-05-18 Centre National de la Recherche Scientifique (C.N.R.S) Methods for diagnosing skin diseases
EP2504357B1 (en) 2009-11-23 2017-08-02 Research Development Foundation Recombinant filaggrin polypeptides for cell importation
JP5771123B2 (ja) * 2011-11-09 2015-08-26 株式会社 資生堂 プロフィラグリンｃ末端ドメイン特異的抗体及びその用途
GB201222881D0 (en) * 2012-12-19 2013-01-30 Univ Dundee Animal model
JP5943945B2 (ja) * 2014-01-29 2016-07-05 株式会社 資生堂 プロフィラグリンｃ末端ドメイン特異的抗体及びその用途
JP6803113B2 (ja) * 2016-07-01 2020-12-23 共栄化学工業株式会社 評価方法及び皮膚外用剤
RU2673804C1 (ru) * 2018-01-25 2018-11-30 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ НАУЧНОЕ УЧРЕЖДЕНИЕ "ФЕДЕРАЛЬНЫЙ ИССЛЕДОВАТЕЛЬСКИЙ ЦЕНТР ИНСТИТУТ ЦИТОЛОГИИ И ГЕНЕТИКИ СИБИРСКОГО ОТДЕЛЕНИЯ РОССИЙСКОЙ АКАДЕМИИ НАУК" (ИЦиГ СО РАН) Способ выявления мутаций 2282del4, R501X, R2447X в гене филаггрина (FLG) при вульгарном ихтиозе и атопическом дерматите
CN112236153B (zh) * 2018-04-05 2025-04-29 阿兹特拉公司 用重组微生物治疗皮肤疾病的方法和组合物
US20210355192A1 (en) * 2018-10-08 2021-11-18 Yale University Selective Binding and Aggregation of Human Keratin in the Skin Barrier Using Human Filaggrin Subdomains SD67 and SD150
CN113092768A (zh) * 2019-12-23 2021-07-09 首都医科大学附属北京世纪坛医院 尿液角蛋白,ii型细胞骨架1及其多肽片段在过敏性疾病中的应用
CN116874576B (zh) * 2023-06-28 2024-03-12 胡荣洋 一种重组人源化丝聚蛋白及其制备方法和应用
CN118460707B (zh) * 2024-07-15 2024-09-17 山东大学 检测寻常鱼鳞病相关flg基因突变的引物组、试剂盒及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2309534A1 (en) * 1997-11-28 1999-06-10 Innogenetics N.V. Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
US6143502A (en) * 1999-03-31 2000-11-07 University Of Utah Research Foundation Dual-luciferase reporter system
US6458538B1 (en) 1999-12-14 2002-10-01 Ptc Therapeutics, Inc. Methods of assaying for compounds that inhibit premature translation termination and nonsense-mediated RNA decay
GB0111324D0 (en) * 2001-05-09 2001-07-04 Unilever Plc Ambient stable beverage
IL159311A0 (en) * 2001-06-13 2004-06-01 Remedies for diseases caused by nonsense mutation
AU2003252136A1 (en) 2002-07-24 2004-02-09 Ptc Therapeutics, Inc. METHODS FOR IDENTIFYING SMALL MOLEDULES THAT MODULATE PREMATURE TRANSLATION TERMINATION AND NONSENSE MEDIATED mRNA DECAY
FI20031927A0 (fi) 2003-12-31 2003-12-31 Faron Pharmaceuticals Oy Terapeuttisesti vaikuttavia aineita ja niiden käyttö
GB0600948D0 (en) 2006-01-18 2006-02-22 Univ Dundee Prevention/Treatment Of Ichthyosis Vulgaris, Atopy And Other Disorders

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