JP2009521921A5 - - Google Patents
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- JP2009521921A5 JP2009521921A5 JP2008548463A JP2008548463A JP2009521921A5 JP 2009521921 A5 JP2009521921 A5 JP 2009521921A5 JP 2008548463 A JP2008548463 A JP 2008548463A JP 2008548463 A JP2008548463 A JP 2008548463A JP 2009521921 A5 JP2009521921 A5 JP 2009521921A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- protein
- acid residues
- seq
- fusion protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0502932-7 | 2005-12-30 | ||
| SE0502932 | 2005-12-30 | ||
| PCT/SE2006/001505 WO2007078239A2 (en) | 2005-12-30 | 2006-12-28 | Spider silk proteins and methods for producing spider silk proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009521921A JP2009521921A (ja) | 2009-06-11 |
| JP2009521921A5 true JP2009521921A5 (https=) | 2010-03-04 |
| JP5192391B2 JP5192391B2 (ja) | 2013-05-08 |
Family
ID=37836847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548463A Active JP5192391B2 (ja) | 2005-12-30 | 2006-12-28 | クモ糸タンパク質およびクモ糸タンパク質の生産方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US8173772B2 (https=) |
| EP (2) | EP1976868B1 (https=) |
| JP (1) | JP5192391B2 (https=) |
| CN (1) | CN101395178B (https=) |
| AU (1) | AU2006333611B2 (https=) |
| CA (1) | CA2635660C (https=) |
| DK (1) | DK1976868T3 (https=) |
| ES (1) | ES2533555T3 (https=) |
| RU (1) | RU2444527C2 (https=) |
| WO (1) | WO2007078239A2 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008154547A2 (en) * | 2007-06-11 | 2008-12-18 | The Regents Of The University Of California | Spider silk dragline polynucleotides, polypeptides and methods of use thereof |
| EP2243792A1 (en) | 2009-04-22 | 2010-10-27 | Spiber Technologies AB | Methods of producing polymers of spider silk proteins |
| EP2421890B1 (en) * | 2009-04-22 | 2015-08-26 | Spiber Technologies AB | Method of producing polymers of spider silk proteins |
| CN101724920B (zh) * | 2009-11-13 | 2011-04-27 | 东华大学 | 干纺制备再生蚕丝纤维的方法 |
| US9233067B2 (en) | 2009-11-30 | 2016-01-12 | Amsilk Gmbh | Silk particles for controlled and sustained delivery of compounds |
| WO2011113446A1 (en) * | 2010-03-17 | 2011-09-22 | Amsilk Gmbh | Method for production of polypeptide containing fibres |
| JP5726282B2 (ja) | 2010-03-18 | 2015-05-27 | スパイバー テクノロジーズ アーベーSpiber Technologies Ab | タンパク質及びポリペプチドの産生 |
| CA2795541C (en) * | 2010-04-12 | 2020-05-26 | Spiber Technologies Ab | Spider silk protein scaffolds for eukaryotic cell culture |
| RU2624036C2 (ru) * | 2010-10-27 | 2017-06-30 | Спибер Текнолоджиз Аб | Структуры слитого белка шелка пауков для связывания с органической мишенью |
| RU2451023C1 (ru) * | 2010-11-25 | 2012-05-20 | Владимир Григорьевич Богуш | Способ получения рекомбинантного белка паутины, слитый белок, рекомбинантная днк, вектор экспрессии, клетка-хозяин и штаммы-продуценты |
| US9617315B2 (en) | 2011-06-01 | 2017-04-11 | Spiber Inc. | Artificial polypeptide fiber and method for producing the same |
| EP2774934B1 (en) | 2011-11-02 | 2017-11-29 | Spiber Inc. | Polypeptide solution, artificial polypeptide fiber production method using same, and polypeptide refining method |
| WO2013065651A1 (ja) * | 2011-11-02 | 2013-05-10 | スパイバー株式会社 | タンパク質溶液及びこれを用いたタンパク質繊維の製造方法 |
| EP2844360B1 (en) | 2012-05-02 | 2018-12-19 | Spiber Technologies AB | Spider silk fusion protein structures without repetitive fragment for binding to an organic target |
| US9856308B2 (en) | 2012-05-02 | 2018-01-02 | Spiber Technologies Ab | Spider silk fusion protein structures incorporating immunoglobulin fragments as affinity ligands |
| WO2014002605A1 (ja) | 2012-06-28 | 2014-01-03 | スパイバー株式会社 | 原着タンパク質繊維及びその製造方法 |
| WO2014052975A1 (en) * | 2012-09-28 | 2014-04-03 | Utah State University | Expression systems and methods of producing spider silk proteins |
| US10899803B2 (en) | 2012-10-17 | 2021-01-26 | Nanyang Technological University | Compounds and methods for the production of suckerin and uses thereof |
| CA2924343C (en) | 2013-09-17 | 2025-09-16 | Bolt Threads, Inc. | PROCESSES AND COMPOSITIONS FOR SYNTHESIZING IMPROVED SILK FIBERS |
| EP3281948B1 (en) | 2015-04-09 | 2020-06-10 | Spiber Inc. | Polar solvent solution and production method thereof |
| EP3281949A4 (en) | 2015-04-09 | 2018-08-22 | Spiber Inc. | Polar solvent solution and production method thereof |
| EP3307765B1 (en) * | 2015-06-11 | 2024-04-10 | Bolt Threads, Inc. | Recombinant protein fiber yarns with improved properties |
| CN105031723B (zh) * | 2015-06-23 | 2017-05-24 | 上海交通大学 | 基于蜘蛛丝蛋白的温敏性水凝胶 |
| JP6863976B2 (ja) * | 2015-06-26 | 2021-04-21 | スピベル テクノロジーズ アクティエボラーグ | 環状rgd細胞結合モチーフ及びその使用 |
| KR102751752B1 (ko) * | 2015-08-10 | 2025-01-09 | 시비스 머테리얼 사이언스 리미티드 | 합성 드래그라인 거미 명주를 제조하기 위한 조성물 및 방법 |
| JP2018159137A (ja) | 2015-08-20 | 2018-10-11 | 国立研究開発法人理化学研究所 | クモ糸様構造を有するポリペプチド繊維の製造方法 |
| WO2017138002A1 (en) | 2016-02-11 | 2017-08-17 | Seevix Material Sciences Ltd. | Composite materials comprising synthetic dragline spider silk |
| US11484624B2 (en) | 2016-05-16 | 2022-11-01 | Spiber Technologies Ab | Spider silk coating of solid surfaces |
| EP3246051A1 (en) | 2016-05-16 | 2017-11-22 | Spiber Technologies AB | Spider silk coating of solid surfaces |
| EP3263593A1 (en) | 2016-07-01 | 2018-01-03 | Anna Rising | Engineered spider silk proteins and uses thereof |
| KR20190046993A (ko) | 2016-09-14 | 2019-05-07 | 볼트 쓰레즈, 인크. | 긴 균일한 재조합 단백질 섬유 |
| JP2020097796A (ja) * | 2017-03-10 | 2020-06-25 | Spiber株式会社 | 人造フィブロイン繊維 |
| JP6337252B1 (ja) * | 2017-03-10 | 2018-06-06 | Spiber株式会社 | 高収縮人造フィブロイン繊維及びその製造方法、並びに人造フィブロイン繊維の収縮方法 |
| WO2018229341A1 (en) | 2017-06-13 | 2018-12-20 | Aalto University Foundation Sr. | Method for producing a condensed adhesive phase of silk fusion proteins |
| JP6713635B2 (ja) * | 2017-07-04 | 2020-06-24 | 内浜化成株式会社 | 複合材および複合材の製造方法 |
| EP3688017A1 (en) | 2017-09-26 | 2020-08-05 | Spiber Technologies AB | Structuring of surface-active macromolecules |
| JP7367977B2 (ja) * | 2018-01-31 | 2023-10-24 | Spiber株式会社 | タンパク質捲縮ステープルの製造方法 |
| CN108985298B (zh) * | 2018-06-19 | 2022-02-18 | 浙江大学 | 一种基于语义一致性的人体衣物分割方法 |
| US12319718B2 (en) | 2019-01-09 | 2025-06-03 | Spiber Inc. | Modified fibroin |
| CN109912720B (zh) * | 2019-03-14 | 2021-12-07 | 天津大学 | 一种蛛丝蛋白的设计合成方法和纺丝 |
| CN115698049A (zh) | 2020-04-23 | 2023-02-03 | 赛威克斯材料科学公司 | 包括牵引蛛丝的化妆品组合物 |
| WO2022048733A1 (en) | 2020-09-01 | 2022-03-10 | Spiber Technologies Ab | Method for producing macroporous scaffolds composed of silk and calcium phosphate |
| CN112080493B (zh) * | 2020-09-07 | 2021-12-28 | 中国科学院天津工业生物技术研究所 | 制备串联重复dna的方法及相关生物材料与应用 |
| WO2022211939A2 (en) * | 2021-02-25 | 2022-10-06 | Washington University | Microbial production of polymeric amyloid fibers having gigapascal tensile strength |
| MX2023012063A (es) | 2021-04-12 | 2024-02-01 | Biocrine Ab | Organoides de islotes pancreáticos como fábricas de proteínas. |
| US12391912B2 (en) | 2021-10-26 | 2025-08-19 | Rensselaer Polytechnic Institute | Systems and methods for increased production of recombinant biopolymers via genome engineering and downregulation of basal expression |
| CN114907467B (zh) * | 2022-05-13 | 2023-09-15 | 四川轻化工大学 | 一种融合碳端的重组蛛丝蛋白及其制备方法与基于重组蛛丝蛋白的载药微球 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0452925B1 (en) | 1990-04-20 | 2000-02-09 | The University Of Wyoming | Isolated DNA coding for spider silk protein, a replicable vector and a transformed cell containing the isolated DNA, and products thereof |
| TW336938B (en) * | 1992-05-21 | 1998-07-21 | Pfizer | Calcium channel blocking polypeptides from filistata hibernalis |
| EP1413585A3 (en) | 1993-06-15 | 2004-08-04 | E.I. Du Pont De Nemours And Company | Novel, recombinantly produced spider silk analogs |
| US5733771A (en) * | 1994-03-14 | 1998-03-31 | University Of Wyoming | cDNAs encoding minor ampullate spider silk proteins |
| IL123398A0 (en) | 1995-08-22 | 1998-09-24 | Agricola Tech Inc | Cloning methods for high strength spider silk proteins |
| US5994099A (en) * | 1997-12-31 | 1999-11-30 | The University Of Wyoming | Extremely elastic spider silk protein and DNA coding therefor |
| US6620917B1 (en) | 2000-01-20 | 2003-09-16 | The United States Of America As Represented By The Secretary Of The Army | Method for the purification and aqueous fiber spinning of spider silks and other structural proteins |
| US6608242B1 (en) | 2000-05-25 | 2003-08-19 | E. I. Du Pont De Nemours And Company | Production of silk-like proteins in plants |
| DE10113781A1 (de) | 2000-06-09 | 2001-12-13 | Ipk Inst Fuer Pflanzengenetik | Synthetische Spinnenseidenproteine und deren Expression in transgenen Pflanzen |
| WO2002099082A2 (en) * | 2001-06-06 | 2002-12-12 | University Of Wyoming | Expression of spider silk proteins in higher plants |
| JP2005502347A (ja) * | 2001-08-29 | 2005-01-27 | ユニバーシティ オブ ワイオミング | クモ糸タンパク質をコードする核酸、ポリペプチド、抗体とそれらの使用方法 |
| AU2003201513A1 (en) | 2002-01-11 | 2003-07-24 | Nexia Biotechnologies, Inc. | Methods of producing silk polypeptides and products thereof |
| WO2003060099A2 (en) | 2002-01-11 | 2003-07-24 | Nexia Biotechnologies, Inc. | Methods and apparatus for spinning spider silk protein |
| AU2003202330A1 (en) | 2002-01-11 | 2003-07-24 | Nexia Biotechnologies, Inc. | Recovery of biofilament proteins from biological fluids |
| GB0218977D0 (en) | 2002-08-15 | 2002-09-25 | Univ York | Polypeptide |
| US20040132978A1 (en) | 2002-11-12 | 2004-07-08 | Fahnestock Stephen R. | Method for purifying and recovering silk proteins in soluble form and uses thereof |
| US7060260B2 (en) | 2003-02-20 | 2006-06-13 | E.I. Du Pont De Nemours And Company | Water-soluble silk proteins in compositions for skin care, hair care or hair coloring |
| FR2871822B1 (fr) | 2004-06-17 | 2007-10-05 | Icopal Sas Soc Par Actions Sim | Isolant mince reflechissant pour sous-toiture |
| EP1609801A1 (en) * | 2004-06-25 | 2005-12-28 | Technische Universität München | Proteins of natural origin and materials made therefrom |
| CN101018806B (zh) | 2004-07-22 | 2014-05-07 | Am丝绸有限责任公司 | 重组蜘蛛丝蛋白 |
| WO2006083514A2 (en) | 2005-01-14 | 2006-08-10 | The Florida International University Board Of Trustees | Transgenic production of spider silk |
| AU2006286753B2 (en) | 2005-08-29 | 2011-08-18 | Amsilk Gmbh | Modified spider silk proteins |
| EP1852470A1 (en) | 2006-05-03 | 2007-11-07 | Technische Universität München | Multilayer Silk Protein Films |
-
2006
- 2006-12-28 DK DK06835913T patent/DK1976868T3/da active
- 2006-12-28 CN CN2006800535908A patent/CN101395178B/zh active Active
- 2006-12-28 AU AU2006333611A patent/AU2006333611B2/en not_active Ceased
- 2006-12-28 EP EP06835913.2A patent/EP1976868B1/en active Active
- 2006-12-28 ES ES06835913.2T patent/ES2533555T3/es active Active
- 2006-12-28 CA CA2635660A patent/CA2635660C/en not_active Expired - Fee Related
- 2006-12-28 RU RU2008131298/10A patent/RU2444527C2/ru active
- 2006-12-28 EP EP15155476.3A patent/EP2899204B1/en active Active
- 2006-12-28 US US12/087,289 patent/US8173772B2/en active Active
- 2006-12-28 JP JP2008548463A patent/JP5192391B2/ja active Active
- 2006-12-28 WO PCT/SE2006/001505 patent/WO2007078239A2/en not_active Ceased
-
2012
- 2012-04-06 US US13/441,118 patent/US8278416B1/en active Active
- 2012-08-29 US US13/598,119 patent/US8618255B2/en active Active
-
2013
- 2013-11-21 US US14/086,244 patent/US8729235B2/en active Active
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