JP2009521526A5 - - Google Patents
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- Publication number
- JP2009521526A5 JP2009521526A5 JP2008548399A JP2008548399A JP2009521526A5 JP 2009521526 A5 JP2009521526 A5 JP 2009521526A5 JP 2008548399 A JP2008548399 A JP 2008548399A JP 2008548399 A JP2008548399 A JP 2008548399A JP 2009521526 A5 JP2009521526 A5 JP 2009521526A5
- Authority
- JP
- Japan
- Prior art keywords
- polyvinyl alcohol
- group
- hec
- hpc
- hpmc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229920000623 Cellulose acetate phthalate Polymers 0.000 claims 2
- 239000001856 Ethyl cellulose Substances 0.000 claims 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- 229940081734 cellulose acetate phthalate Drugs 0.000 claims 2
- 229920001249 ethyl cellulose Polymers 0.000 claims 2
- 235000019325 ethyl cellulose Nutrition 0.000 claims 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- 229920000609 methyl cellulose Polymers 0.000 claims 2
- 239000001923 methylcellulose Substances 0.000 claims 2
- 235000019739 Dicalciumphosphate Nutrition 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- 229920002845 Poly(methacrylic acid) Polymers 0.000 claims 1
- 239000004698 Polyethylene Substances 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 239000001506 calcium phosphate Substances 0.000 claims 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 claims 1
- 229940038472 dicalcium phosphate Drugs 0.000 claims 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 claims 1
- 229920000578 graft copolymer Polymers 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229920000573 polyethylene Polymers 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 229940079832 sodium starch glycolate Drugs 0.000 claims 1
- 229920003109 sodium starch glycolate Polymers 0.000 claims 1
- 239000008109 sodium starch glycolate Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020050130531A KR100742432B1 (ko) | 2005-12-27 | 2005-12-27 | 암로디핀 캠실레이트 및 심바스타틴을 포함하는 복합제제,및 이의 제조방법 |
| PCT/KR2006/005658 WO2007075009A1 (en) | 2005-12-27 | 2006-12-22 | Complex formulation comprising amlodipine camsylate and simvastatin and method for preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009521526A JP2009521526A (ja) | 2009-06-04 |
| JP2009521526A5 true JP2009521526A5 (enExample) | 2009-10-01 |
Family
ID=38218207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548399A Withdrawn JP2009521526A (ja) | 2005-12-27 | 2006-12-22 | カンシル酸アムロジピン及びシンバスタチンを含む複合製剤及びその製造方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20090005425A1 (enExample) |
| EP (1) | EP1978956A4 (enExample) |
| JP (1) | JP2009521526A (enExample) |
| KR (1) | KR100742432B1 (enExample) |
| CN (1) | CN101346140A (enExample) |
| AU (1) | AU2006330199A1 (enExample) |
| BR (1) | BRPI0620790A2 (enExample) |
| CA (1) | CA2634639A1 (enExample) |
| IL (1) | IL192148A0 (enExample) |
| RU (1) | RU2008130873A (enExample) |
| WO (1) | WO2007075009A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9161933B2 (en) * | 2009-01-23 | 2015-10-20 | Hanmi Science Co., Ltd | Solid pharmaceutical composition comprising amlodipine and losartan and process for producing same |
| JP6081058B2 (ja) * | 2009-03-19 | 2017-02-15 | 第一三共株式会社 | 包装により安定保存された固形製剤 |
| CN101836981B (zh) * | 2009-12-01 | 2011-12-14 | 严洁 | 复方缬沙坦苯磺酸氨氯地平药物组合物及其制备方法 |
| AU2011226687A1 (en) | 2010-03-11 | 2012-10-11 | University Of Louisville Research Foundation, Inc. | Methods of predicting and decreasing the risk of pregnancy loss |
| KR20120068277A (ko) * | 2010-12-17 | 2012-06-27 | 한미사이언스 주식회사 | ＨＭＧ－ＣｏＡ 환원효소 억제제 및 아스피린을 포함하는 약제학적 복합제제 |
| MX2014001823A (es) | 2011-08-15 | 2014-08-21 | Technion Res & Dev Foundation | Combinaciones de corroles y estatinas. |
| TWI586353B (zh) * | 2012-10-12 | 2017-06-11 | Ea Pharma Co Ltd | Pharmaceutical preparations containing calcium antagonists and angiotensin II receptor antagonists |
| KR20190043076A (ko) | 2017-10-17 | 2019-04-25 | 한미약품 주식회사 | 암로디핀, 로자탄 및 로수바스타틴을 포함하는 당뇨병을 동반한 심혈관계 질환의 예방 또는 치료용 약학 조성물 및 이를 포함하는 복합제제 |
| KR20200009101A (ko) | 2017-10-17 | 2020-01-29 | 한미약품 주식회사 | 암로디핀, 로자탄 및 로수바스타틴을 포함하는 당뇨병을 동반한 심혈관계 질환의 예방 또는 치료용 약학 조성물 및 이를 포함하는 복합제제 |
| KR102306888B1 (ko) | 2019-11-25 | 2021-09-29 | 성균관대학교산학협력단 | 구멍쇠미역으로부터 분리된 신규 화합물을 유효성분으로 포함하는 동맥경화 예방 및 치료용 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL133957A0 (en) | 1997-08-29 | 2001-04-30 | Pfizer Prod Inc | Combination therapy comprising amlodipine and a statin compound |
| US20030092745A1 (en) | 2000-02-25 | 2003-05-15 | Pfizer Inc. | Combination therapy |
| AU2001284413A1 (en) | 2000-08-30 | 2002-03-13 | Sankyo Company Limited | Medicinal compositions for preventing or treating heart failure |
| DE10224612A1 (de) * | 2002-06-04 | 2003-12-24 | Lohmann Therapie Syst Lts | Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung |
| MXPA05007876A (es) * | 2003-01-27 | 2005-09-21 | Hanmi Pharm Ind Co Ltd | Camsilato de amlodipino amorfo, estable, proceso para preparar el mismo y composicion para la administracion oral del mismo. |
| US7611728B2 (en) | 2003-09-05 | 2009-11-03 | Supernus Pharmaceuticals, Inc. | Osmotic delivery of therapeutic compounds by solubility enhancement |
| WO2006059217A1 (en) * | 2004-12-01 | 2006-06-08 | Ranbaxy Laboratories Limited | Stable solid dosage forms of amlodipine besylate and processes for their preparation |
| KR100582347B1 (ko) * | 2004-12-30 | 2006-05-22 | 한미약품 주식회사 | 3-하이드록시-3-메틸글루타릴 조효소 ａ 환원효소 억제제및 고혈압 치료제의 복합제제 및 그의 제조방법 |
-
2005
- 2005-12-27 KR KR1020050130531A patent/KR100742432B1/ko not_active Expired - Fee Related
-
2006
- 2006-12-22 AU AU2006330199A patent/AU2006330199A1/en not_active Abandoned
- 2006-12-22 EP EP06835362A patent/EP1978956A4/en not_active Withdrawn
- 2006-12-22 CN CNA2006800492048A patent/CN101346140A/zh active Pending
- 2006-12-22 US US12/159,418 patent/US20090005425A1/en not_active Abandoned
- 2006-12-22 WO PCT/KR2006/005658 patent/WO2007075009A1/en not_active Ceased
- 2006-12-22 CA CA002634639A patent/CA2634639A1/en not_active Abandoned
- 2006-12-22 RU RU2008130873/15A patent/RU2008130873A/ru not_active Application Discontinuation
- 2006-12-22 BR BRPI0620790-1A patent/BRPI0620790A2/pt not_active IP Right Cessation
- 2006-12-22 JP JP2008548399A patent/JP2009521526A/ja not_active Withdrawn
-
2008
- 2008-06-12 IL IL192148A patent/IL192148A0/en unknown