JP2009521526A - カンシル酸アムロジピン及びシンバスタチンを含む複合製剤及びその製造方法 - Google Patents
カンシル酸アムロジピン及びシンバスタチンを含む複合製剤及びその製造方法 Download PDFInfo
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- JP2009521526A JP2009521526A JP2008548399A JP2008548399A JP2009521526A JP 2009521526 A JP2009521526 A JP 2009521526A JP 2008548399 A JP2008548399 A JP 2008548399A JP 2008548399 A JP2008548399 A JP 2008548399A JP 2009521526 A JP2009521526 A JP 2009521526A
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- Prior art keywords
- amlodipine
- combined preparation
- simvastatin
- film layer
- cansylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 229960000528 amlodipine Drugs 0.000 title claims abstract description 78
- 238000002360 preparation method Methods 0.000 title claims abstract description 54
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- RYMZZMVNJRMUDD-HGQWONQESA-N simvastatin Chemical compound C([C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@@H]([C@H]12)OC(=O)C(C)(C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1 RYMZZMVNJRMUDD-HGQWONQESA-N 0.000 title claims abstract description 32
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020050130531A KR100742432B1 (ko) | 2005-12-27 | 2005-12-27 | 암로디핀 캠실레이트 및 심바스타틴을 포함하는 복합제제,및 이의 제조방법 |
| PCT/KR2006/005658 WO2007075009A1 (en) | 2005-12-27 | 2006-12-22 | Complex formulation comprising amlodipine camsylate and simvastatin and method for preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009521526A true JP2009521526A (ja) | 2009-06-04 |
| JP2009521526A5 JP2009521526A5 (enExample) | 2009-10-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548399A Withdrawn JP2009521526A (ja) | 2005-12-27 | 2006-12-22 | カンシル酸アムロジピン及びシンバスタチンを含む複合製剤及びその製造方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20090005425A1 (enExample) |
| EP (1) | EP1978956A4 (enExample) |
| JP (1) | JP2009521526A (enExample) |
| KR (1) | KR100742432B1 (enExample) |
| CN (1) | CN101346140A (enExample) |
| AU (1) | AU2006330199A1 (enExample) |
| BR (1) | BRPI0620790A2 (enExample) |
| CA (1) | CA2634639A1 (enExample) |
| IL (1) | IL192148A0 (enExample) |
| RU (1) | RU2008130873A (enExample) |
| WO (1) | WO2007075009A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014501240A (ja) * | 2010-12-17 | 2014-01-20 | ハンミ・サイエンス・カンパニー・リミテッド | ＨＭＧ−ＣｏＡレダクターゼ阻害剤およびアスピリンを含む医薬複合製剤 |
| WO2014058046A1 (ja) * | 2012-10-12 | 2014-04-17 | 味の素株式会社 | カルシウム拮抗薬／アンジオテンシンｉｉ受容体拮抗薬含有医薬製剤 |
| JP2014521738A (ja) * | 2011-08-15 | 2014-08-28 | テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド | コロールおよびスタチンの併用 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY173823A (en) * | 2009-01-23 | 2020-02-24 | Hanmi Science Co Ltd | Solid pharmaceutical composition comprising amlodipine and losartan and process for producing same |
| WO2010107081A1 (ja) * | 2009-03-19 | 2010-09-23 | 第一三共株式会社 | 包装により安定保存された固形製剤 |
| CN101836981B (zh) * | 2009-12-01 | 2011-12-14 | 严洁 | 复方缬沙坦苯磺酸氨氯地平药物组合物及其制备方法 |
| WO2011112993A2 (en) | 2010-03-11 | 2011-09-15 | University Of Louisville Research Foundation, Inc. | Methods of predicting and decreasing the risk of pregnancy loss |
| KR20200009101A (ko) | 2017-10-17 | 2020-01-29 | 한미약품 주식회사 | 암로디핀, 로자탄 및 로수바스타틴을 포함하는 당뇨병을 동반한 심혈관계 질환의 예방 또는 치료용 약학 조성물 및 이를 포함하는 복합제제 |
| KR20190043076A (ko) | 2017-10-17 | 2019-04-25 | 한미약품 주식회사 | 암로디핀, 로자탄 및 로수바스타틴을 포함하는 당뇨병을 동반한 심혈관계 질환의 예방 또는 치료용 약학 조성물 및 이를 포함하는 복합제제 |
| KR102306888B1 (ko) | 2019-11-25 | 2021-09-29 | 성균관대학교산학협력단 | 구멍쇠미역으로부터 분리된 신규 화합물을 유효성분으로 포함하는 동맥경화 예방 및 치료용 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ502283A (en) | 1997-08-29 | 2002-05-31 | Pfizer Prod Inc | Cardiovascular therapy comprising amlodipine and a statin compound in amounts that are synergistically effective |
| US20030092745A1 (en) | 2000-02-25 | 2003-05-15 | Pfizer Inc. | Combination therapy |
| EP1314425A4 (en) | 2000-08-30 | 2004-06-02 | Sankyo Co | MEDICINAL COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF HEART FAILURE |
| DE10224612A1 (de) * | 2002-06-04 | 2003-12-24 | Lohmann Therapie Syst Lts | Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung |
| BRPI0407038A (pt) | 2003-01-27 | 2006-01-17 | Hanmi Pharm Ind Co Ltd | Camsilato de amlodipina amorfo estável, processo para a preparação do mesmo e composição para administração oral deste |
| US7611728B2 (en) | 2003-09-05 | 2009-11-03 | Supernus Pharmaceuticals, Inc. | Osmotic delivery of therapeutic compounds by solubility enhancement |
| WO2006059217A1 (en) * | 2004-12-01 | 2006-06-08 | Ranbaxy Laboratories Limited | Stable solid dosage forms of amlodipine besylate and processes for their preparation |
| KR100582347B1 (ko) * | 2004-12-30 | 2006-05-22 | 한미약품 주식회사 | 3-하이드록시-3-메틸글루타릴 조효소 ａ 환원효소 억제제및 고혈압 치료제의 복합제제 및 그의 제조방법 |
-
2005
- 2005-12-27 KR KR1020050130531A patent/KR100742432B1/ko not_active Expired - Fee Related
-
2006
- 2006-12-22 EP EP06835362A patent/EP1978956A4/en not_active Withdrawn
- 2006-12-22 BR BRPI0620790-1A patent/BRPI0620790A2/pt not_active IP Right Cessation
- 2006-12-22 WO PCT/KR2006/005658 patent/WO2007075009A1/en not_active Ceased
- 2006-12-22 CA CA002634639A patent/CA2634639A1/en not_active Abandoned
- 2006-12-22 US US12/159,418 patent/US20090005425A1/en not_active Abandoned
- 2006-12-22 CN CNA2006800492048A patent/CN101346140A/zh active Pending
- 2006-12-22 RU RU2008130873/15A patent/RU2008130873A/ru not_active Application Discontinuation
- 2006-12-22 JP JP2008548399A patent/JP2009521526A/ja not_active Withdrawn
- 2006-12-22 AU AU2006330199A patent/AU2006330199A1/en not_active Abandoned
-
2008
- 2008-06-12 IL IL192148A patent/IL192148A0/en unknown
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014501240A (ja) * | 2010-12-17 | 2014-01-20 | ハンミ・サイエンス・カンパニー・リミテッド | ＨＭＧ−ＣｏＡレダクターゼ阻害剤およびアスピリンを含む医薬複合製剤 |
| JP2014521738A (ja) * | 2011-08-15 | 2014-08-28 | テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド | コロールおよびスタチンの併用 |
| US9642860B2 (en) | 2011-08-15 | 2017-05-09 | Technion Research & Development Foundation Limited | Combinations of corroles and statins |
| WO2014058046A1 (ja) * | 2012-10-12 | 2014-04-17 | 味の素株式会社 | カルシウム拮抗薬／アンジオテンシンｉｉ受容体拮抗薬含有医薬製剤 |
| JP2015007116A (ja) * | 2012-10-12 | 2015-01-15 | 味の素株式会社 | カルシウム拮抗薬／アンジオテンシンｉｉ受容体拮抗薬含有医薬製剤 |
| JP5854371B2 (ja) * | 2012-10-12 | 2016-02-09 | 味の素株式会社 | カルシウム拮抗薬／アンジオテンシンｉｉ受容体拮抗薬含有医薬製剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006330199A1 (en) | 2007-07-05 |
| CN101346140A (zh) | 2009-01-14 |
| US20090005425A1 (en) | 2009-01-01 |
| BRPI0620790A2 (pt) | 2011-11-22 |
| CA2634639A1 (en) | 2007-07-05 |
| RU2008130873A (ru) | 2010-02-10 |
| EP1978956A1 (en) | 2008-10-15 |
| KR100742432B1 (ko) | 2007-07-24 |
| WO2007075009A1 (en) | 2007-07-05 |
| KR20070068658A (ko) | 2007-07-02 |
| EP1978956A4 (en) | 2009-08-19 |
| IL192148A0 (en) | 2009-08-03 |
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