JP2009517009A - エリスロポエチンポリペプチド及びそれらの使用 - Google Patents

エリスロポエチンポリペプチド及びそれらの使用 Download PDF

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Publication number
JP2009517009A
JP2009517009A JP2008541750A JP2008541750A JP2009517009A JP 2009517009 A JP2009517009 A JP 2009517009A JP 2008541750 A JP2008541750 A JP 2008541750A JP 2008541750 A JP2008541750 A JP 2008541750A JP 2009517009 A JP2009517009 A JP 2009517009A
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Prior art keywords
polypeptide
seq
amino acid
amino acids
epo
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JP2008541750A
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Japanese (ja)
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JP2009517009A5 (enExample
Inventor
アブデルラヒーム、ハーディ
プリマス、グエナエル
クヴァトクコ、ヨランドゥ
マウンドレル、キンゼー
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ラボラトワ セローノ エス.エイ.
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Publication of JP2009517009A publication Critical patent/JP2009517009A/ja
Publication of JP2009517009A5 publication Critical patent/JP2009517009A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008541750A 2005-11-24 2006-11-23 エリスロポエチンポリペプチド及びそれらの使用 Pending JP2009517009A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP05111262 2005-11-24
EP05111265 2005-11-24
US75370605P 2005-12-22 2005-12-22
US75366805P 2005-12-22 2005-12-22
PCT/EP2006/068859 WO2007060213A2 (en) 2005-11-24 2006-11-23 Erythropoietin polypeptides and uses thereof

Publications (2)

Publication Number Publication Date
JP2009517009A true JP2009517009A (ja) 2009-04-30
JP2009517009A5 JP2009517009A5 (enExample) 2010-02-04

Family

ID=37807876

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008541750A Pending JP2009517009A (ja) 2005-11-24 2006-11-23 エリスロポエチンポリペプチド及びそれらの使用

Country Status (7)

Country Link
US (1) US20080260746A1 (enExample)
EP (1) EP1966237A2 (enExample)
JP (1) JP2009517009A (enExample)
AU (1) AU2006316450A1 (enExample)
CA (1) CA2621705A1 (enExample)
IL (1) IL191426A (enExample)
WO (1) WO2007060213A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4484115B2 (ja) * 2004-02-09 2010-06-16 パイオニア株式会社 光学素子、光ピックアップ及び情報記録再生装置
US7625564B2 (en) 2006-01-27 2009-12-01 Novagen Holding Corporation Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
WO2008074851A2 (en) * 2006-12-19 2008-06-26 Nokad Method for inhibiting the expression of endogenous erythropoietin (epo)
AU2008261212A1 (en) * 2007-06-15 2008-12-18 University Of Zurich Treatment for Alzheimer' s disease
WO2009012600A1 (en) * 2007-07-26 2009-01-29 Novagen Holding Corporation Fusion proteins
US9732132B2 (en) * 2011-01-14 2017-08-15 Vanderbilt University Therapeutic compositions and methods for disorders associated with neuronal degeneration
CN102816853A (zh) * 2012-08-30 2012-12-12 山东百福基因科技有限公司 运动机能相关基因epo荧光检测试剂盒及检测方法
LT2928921T (lt) 2012-12-05 2021-04-26 Novartis Ag Kompozicijos ir būdai, skirti antikūnams nukreipti į epo
US20210340241A1 (en) * 2014-06-12 2021-11-04 Andremacon S.R.L. Use of negative functional modulators of erythropoietin for therapy
WO2017025928A2 (en) 2015-08-12 2017-02-16 Novartis Ag Methods of treating ophthalmic disorders
WO2018155997A1 (ko) * 2017-02-27 2018-08-30 재단법인 대구경북과학기술원 에리스로포이에틴 유래 펩티드의 세포손상방지에 효과를 통한 활용
WO2022159414A1 (en) 2021-01-22 2022-07-28 University Of Rochester Erythropoietin for gastroinfestinal dysfunction

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60500558A (ja) * 1983-02-04 1985-04-25 キリン−アムジェン、インコ−ポレ−テッド Atcc hb8209 及びそのエリスロポエチンに対するモノクロ−ナル抗体
JPH10101574A (ja) * 1996-08-06 1998-04-21 Snow Brand Milk Prod Co Ltd 増殖性臓器疾患治療・改善剤
WO2004003176A2 (en) * 2002-07-01 2004-01-08 The Kenneth S. Warren Institute, Inc. Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
DE3923963A1 (de) * 1989-07-20 1991-01-31 Behringwerke Ag Muteine des menschlichen erythropoetins, ihre herstellung und ihre verwendung
CA2268001A1 (en) * 1996-10-25 1998-05-07 G.D. Searle & Co. Circularly permuted erythropoietin receptor agonists
US7033774B2 (en) * 1997-04-21 2006-04-25 Glycozyme, Inc. Determination of recombinant glycosylated proteins and peptides in biological fluids
US20040229779A1 (en) * 1999-05-14 2004-11-18 Ramesh Kekuda Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US6974684B2 (en) * 2001-08-08 2005-12-13 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use
EP2261250B1 (en) * 2001-12-21 2015-07-01 Human Genome Sciences, Inc. GCSF-Albumin fusion proteins
WO2004089282A2 (en) * 2002-08-09 2004-10-21 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US7846466B2 (en) * 2004-06-10 2010-12-07 Northwestern University Biodegradable scaffolds and uses thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60500558A (ja) * 1983-02-04 1985-04-25 キリン−アムジェン、インコ−ポレ−テッド Atcc hb8209 及びそのエリスロポエチンに対するモノクロ−ナル抗体
JPH10101574A (ja) * 1996-08-06 1998-04-21 Snow Brand Milk Prod Co Ltd 増殖性臓器疾患治療・改善剤
WO2004003176A2 (en) * 2002-07-01 2004-01-08 The Kenneth S. Warren Institute, Inc. Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012011068; Science (2004) vol.305, no.5681, p.239-242 *
JPN6012011069; J. Biol. Chem. (1993) vol.268, no.21, p.15983-15993 *
JPN6012011070; Nat. Rev. Neurosci. (Jun 2005) vol.6, no.6, p.484-494 *

Also Published As

Publication number Publication date
WO2007060213A3 (en) 2008-08-14
CA2621705A1 (en) 2007-05-31
AU2006316450A1 (en) 2007-05-31
US20080260746A1 (en) 2008-10-23
IL191426A (en) 2012-05-31
EP1966237A2 (en) 2008-09-10
WO2007060213A2 (en) 2007-05-31

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