JP2009515180A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009515180A5 JP2009515180A5 JP2008539439A JP2008539439A JP2009515180A5 JP 2009515180 A5 JP2009515180 A5 JP 2009515180A5 JP 2008539439 A JP2008539439 A JP 2008539439A JP 2008539439 A JP2008539439 A JP 2008539439A JP 2009515180 A5 JP2009515180 A5 JP 2009515180A5
- Authority
- JP
- Japan
- Prior art keywords
- core
- polymer
- particle
- coating
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 claims 20
- 229920000642 polymer Polymers 0.000 claims 12
- 239000011248 coating agent Substances 0.000 claims 9
- 238000000576 coating method Methods 0.000 claims 9
- 230000002209 hydrophobic effect Effects 0.000 claims 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 4
- 239000000538 analytical sample Substances 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 3
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 claims 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical group OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 2
- 239000004215 Carbon black (E152) Substances 0.000 claims 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical group OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 claims 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims 2
- 230000002776 aggregation Effects 0.000 claims 2
- 150000001412 amines Chemical group 0.000 claims 2
- 150000001732 carboxylic acid derivatives Chemical group 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 150000002118 epoxides Chemical group 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 229930195733 hydrocarbon Natural products 0.000 claims 2
- 150000002430 hydrocarbons Chemical class 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 150000003141 primary amines Chemical class 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 150000003335 secondary amines Chemical class 0.000 claims 2
- 150000003384 small molecules Chemical class 0.000 claims 2
- 150000003512 tertiary amines Chemical class 0.000 claims 2
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 claims 1
- 229920000936 Agarose Polymers 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 229920000881 Modified starch Polymers 0.000 claims 1
- 239000004368 Modified starch Substances 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 229920002873 Polyethylenimine Polymers 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical group [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims 1
- 125000005396 acrylic acid ester group Chemical group 0.000 claims 1
- 238000005054 agglomeration Methods 0.000 claims 1
- 238000004220 aggregation Methods 0.000 claims 1
- 229920005603 alternating copolymer Polymers 0.000 claims 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 238000013375 chromatographic separation Methods 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000007720 emulsion polymerization reaction Methods 0.000 claims 1
- 229910002804 graphite Inorganic materials 0.000 claims 1
- 239000010439 graphite Substances 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 125000005397 methacrylic acid ester group Chemical group 0.000 claims 1
- 235000019426 modified starch Nutrition 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920001451 polypropylene glycol Polymers 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 238000012673 precipitation polymerization Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000004627 regenerated cellulose Substances 0.000 claims 1
- 229910000077 silane Inorganic materials 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0502485A SE0502485L (sv) | 2005-11-09 | 2005-11-09 | Partiklar |
| PCT/EP2006/068311 WO2007054548A2 (en) | 2005-11-09 | 2006-11-09 | Particles for use in a mobile solid chromatography phase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009515180A JP2009515180A (ja) | 2009-04-09 |
| JP2009515180A5 true JP2009515180A5 (https=) | 2009-12-17 |
Family
ID=38015424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008539439A Pending JP2009515180A (ja) | 2005-11-09 | 2006-11-09 | 粒子 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090236519A1 (https=) |
| EP (1) | EP1963005B1 (https=) |
| JP (1) | JP2009515180A (https=) |
| CN (1) | CN101336133A (https=) |
| AT (1) | ATE509697T1 (https=) |
| SE (1) | SE0502485L (https=) |
| WO (1) | WO2007054548A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794837B2 (en) | 2007-08-06 | 2010-09-14 | The United States of America as represented by the Secretary of Commerce, the National Institute of Standards and Technology | Covalently immobilized fluorinated carboxylic acid stationary phase for liquid chromatography |
| WO2009131526A1 (en) * | 2008-04-22 | 2009-10-29 | Ge Healthcare Bio-Sciences Ab | Chromatography medium |
| CN102958602A (zh) * | 2010-07-09 | 2013-03-06 | 通用电气健康护理生物科学股份公司 | 层析方法及为此使用的介质 |
| CN102847514B (zh) * | 2012-09-26 | 2015-06-17 | 复旦大学 | 可用作毛细管电色谱准固定相的纳米介孔材料及其制备方法 |
| US10018635B2 (en) | 2014-07-30 | 2018-07-10 | Novilytic, LLC | Method for analyzing samples of a biological fluid |
| JP6409528B2 (ja) * | 2014-11-27 | 2018-10-24 | Jnc株式会社 | アミノ基を含むイオン交換基とブチル基を含む疎水性基とを有する多孔性セルロース粒子及びそれを含むクロマトグラフィー担体ならびにｂ型肝炎ウィルスのウィルス様粒子の精製方法 |
| CN104741090B (zh) * | 2015-03-19 | 2017-08-29 | 深圳职业技术学院 | 一种扩张床吸附(eba)介质和其制备方法 |
| JP7725953B2 (ja) * | 2021-09-06 | 2025-08-20 | Jnc株式会社 | 多孔質粒子とその製造方法、およびこれを用いたクロマトグラフィー用充填剤 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4029583A (en) * | 1975-02-28 | 1977-06-14 | Purdue Research Foundation | Chromatographic supports and methods and apparatus for preparing the same |
| SE8205908D0 (sv) * | 1982-10-18 | 1982-10-18 | Pharmacia Diagnostics Ab | Sett att bilda polymerskikt |
| US5240602A (en) * | 1987-06-08 | 1993-08-31 | Chromatochem, Inc. | Chromatographic material |
| JP2761881B2 (ja) * | 1988-03-10 | 1998-06-04 | チッソ株式会社 | 抗体を固定化したアフイニテイクロマトグラフイ用担体 |
| US5043062A (en) * | 1989-02-21 | 1991-08-27 | Eastman Kodak Company | High performance affinity chromatography column comprising non-porous, nondisperse polymeric packing material |
| US5030352A (en) * | 1990-01-25 | 1991-07-09 | Purdue Research Foundation | Coated media for chromatography |
| US6039876A (en) * | 1992-07-24 | 2000-03-21 | Yang; Yan-Bo | Hydrophilic polystrene divinylbenzene based matrixes for chromatography |
| US5653875A (en) * | 1994-02-04 | 1997-08-05 | Supelco, Inc. | Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices |
| US20010018179A1 (en) * | 1998-01-06 | 2001-08-30 | Derek J. Hei | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use |
| SE9700769D0 (sv) * | 1997-03-04 | 1997-03-04 | Pharmacia Biotech Ab | Matriser för separation och separation som utnyttjar matriserna |
| US20020104801A1 (en) * | 1998-04-06 | 2002-08-08 | Nicolas Voute | Small dense microporous solid support materials, their preparation,and use for purification of large macromolecules and bioparticles |
| SE9803838D0 (sv) * | 1998-11-09 | 1998-11-09 | Knut Irgum | A chromatography method and a column material useful in said method |
| ATE464118T1 (de) * | 1999-02-05 | 2010-04-15 | Waters Technologies Corp | Poröse hybridpartikel zur chromatographischen trennung |
| SE9904272D0 (sv) * | 1999-11-25 | 1999-11-25 | Amersham Pharm Biotech Ab | A method for selective removal of a substance from samples containing compounds having nucleic acid structure |
| DE19958390A1 (de) * | 1999-12-03 | 2001-06-07 | Bayer Ag | Verfahren zur Herstellung monodisperser Adsorberharze und deren Verwendung |
| US6531523B1 (en) * | 2000-10-10 | 2003-03-11 | Renal Tech International, Llc | Method of making biocompatible polymeric adsorbing material for purification of physiological fluids of organism |
| DE60235206D1 (de) * | 2001-06-01 | 2010-03-11 | Upfront Chromatography As Kope | Fraktionierung von proteinhaltigen Mischungen |
| US20030125656A1 (en) * | 2001-12-31 | 2003-07-03 | Vadim Davankov | Hemo-and biocompatible beaded polymeric material for purification of physiological fluids of organism, method of producing the material, as well as method of and device for purification of physiological fluids of organism with use of the material |
| SE525599C2 (sv) | 2002-04-11 | 2005-03-15 | Staffan Nilsson | Analys och separation av provkomponenter |
| FR2838655B1 (fr) * | 2002-04-23 | 2004-06-25 | Centre Nat Rech Scient | Capsules composites complexantes |
| JP2004099433A (ja) * | 2002-08-22 | 2004-04-02 | Japan Science & Technology Agency | 金属イオンで一部置換または表面担持されたリン酸カルシウム多孔質球形粒子とリン酸カルシウム多孔質多層球形粒子 |
| SE0202551D0 (sv) * | 2002-08-27 | 2002-08-27 | Amersham Biosciences Ab | Chromatographic two-layer particles |
| US6909091B2 (en) | 2003-05-30 | 2005-06-21 | Nanosep Ab | Separation and analysis of sample components |
| CN100434357C (zh) * | 2003-08-22 | 2008-11-19 | 独立行政法人物质·材料研究机构 | 用金属离子部分取代或表面担载金属离子的磷酸钙多孔质多层球形粒子 |
| US8137548B2 (en) * | 2003-10-17 | 2012-03-20 | Zirchrom Separations, Inc. | Chelator-modified inorganic oxide particles |
| SE0302911D0 (sv) * | 2003-10-31 | 2003-10-31 | Amersham Biosciences Ab | Novel separation matrix |
| JP4300104B2 (ja) * | 2003-12-16 | 2009-07-22 | 大日本住友製薬株式会社 | （１−ヒドロキシエチリデン）ビス−フォスフォネートの分析方法 |
| WO2005073711A2 (en) * | 2004-01-20 | 2005-08-11 | Pall Corporation | Chromatographic material for the absorption of proteins at physiological ionic strength |
| CN100422230C (zh) * | 2004-01-28 | 2008-10-01 | 大日本油墨化学工业株式会社 | 芯-壳型高吸液性树脂粒子的制造方法 |
| US20050181378A1 (en) * | 2004-02-18 | 2005-08-18 | Applera Corporation | Polyelectrolyte-coated size-exclusion ion-exchange particles |
| JP3809177B2 (ja) * | 2004-05-24 | 2006-08-16 | 株式会社資生堂 | アフィニティー粒子及びアフィニティー分離方法 |
-
2005
- 2005-11-09 SE SE0502485A patent/SE0502485L/xx not_active Application Discontinuation
-
2006
- 2006-11-09 WO PCT/EP2006/068311 patent/WO2007054548A2/en not_active Ceased
- 2006-11-09 US US12/093,085 patent/US20090236519A1/en not_active Abandoned
- 2006-11-09 EP EP06829967A patent/EP1963005B1/en not_active Not-in-force
- 2006-11-09 CN CNA200680048662XA patent/CN101336133A/zh active Pending
- 2006-11-09 AT AT06829967T patent/ATE509697T1/de not_active IP Right Cessation
- 2006-11-09 JP JP2008539439A patent/JP2009515180A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110520216B (zh) | 蛋白质分离用的多峰色谱介质 | |
| Huang et al. | Surface-initiated radical polymerization on porous silica | |
| Lin et al. | Facile preparation of zwitterionic organic-silica hybrid monolithic capillary column with an improved “one-pot” approach for hydrophilic-interaction liquid chromatography (HILIC) | |
| Pérez et al. | Surface imprinting of cholesterol on submicrometer core− shell emulsion particles | |
| Jain et al. | Applications of polymer brushes in protein analysis and purification | |
| Kempe et al. | Development and evaluation of spherical molecularly imprinted polymer beads | |
| Nagase et al. | Monolithic silica rods grafted with thermoresponsive anionic polymer brushes for high-speed separation of basic biomolecules and peptides | |
| Unsal et al. | Preparation of an ion-exchange chromatographic support by a “grafting from” strategy based on atom transfer radical polymerization | |
| Li et al. | Surface protein imprinted core–shell particles for high selective lysozyme recognition prepared by reversible addition–fragmentation chain transfer strategy | |
| Hemström et al. | Atom-transfer radical graft polymerization initiated directly from silica applied to functionalization of stationary phases for high-performance liquid chromatography in the hydrophilic interaction chromatography mode | |
| CA2942134C (en) | Robust antibody purification | |
| US20080152939A1 (en) | Magnetic Beads | |
| JP2009515180A5 (https=) | ||
| CN106256434B (zh) | 离子交换色谱柱、方法及其系统 | |
| JP2002210377A (ja) | アニオン交換体、その製造方法及びそれを用いた用途 | |
| Bi et al. | Construction of a biomimetic surface on microfluidic chips for biofouling resistance | |
| JP2009530629A (ja) | 乱用薬物の結合 | |
| US20170146528A1 (en) | Solid support, ligand-bound solid support, detection or separation method for target substance, solid support production method, and ligand-bound solid support production method | |
| Tominaga et al. | Effective recognition on the surface of a polymer prepared by molecular imprinting using ionic complex | |
| Ongkudon et al. | Anion exchange chromatography of 4.2 kbp plasmid based vaccine (pcDNA3F) from alkaline lysed E. coli lysate using amino functionalised polymethacrylate conical monolith | |
| JP4984025B2 (ja) | 有機ポリマー粒子およびその製造方法、ならびにプローブ結合粒子 | |
| US20090236519A1 (en) | Particles | |
| US9758542B2 (en) | Protein chromatography matrices with hydrophilic copolymer coatings | |
| JP2007170907A (ja) | アルコキシアルキルアクリレートがグラフト重合した充填剤 | |
| JP2002055093A (ja) | 生体試料中の薬物の分離方法及びそれに用いる分離剤 |