JP2009515180A - 粒子 - Google Patents

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Publication number
JP2009515180A
JP2009515180A JP2008539439A JP2008539439A JP2009515180A JP 2009515180 A JP2009515180 A JP 2009515180A JP 2008539439 A JP2008539439 A JP 2008539439A JP 2008539439 A JP2008539439 A JP 2008539439A JP 2009515180 A JP2009515180 A JP 2009515180A
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JP
Japan
Prior art keywords
particles
particle
core
sample
separation
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Pending
Application number
JP2008539439A
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English (en)
Japanese (ja)
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JP2009515180A5 (https=
Inventor
ビベルイ，ペテル
スペーゲル，ペテル
Original Assignee
ナノセプ アクティエボラーグ
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Publication of JP2009515180A publication Critical patent/JP2009515180A/ja
Publication of JP2009515180A5 publication Critical patent/JP2009515180A5/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/58—Conditioning of the sorbent material or stationary liquid the sorbent moving as a whole
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/102—Process control, e.g. determination or optimization of process parameters; Programmable logic control [PLC]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1801—Radial flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1892—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds or centrifugal chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1894—Liquid-liquid chromatography, e.g. centrifugal partition chromatography or extraction chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1896—Membrane chromatography or membrane adsorbers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/206—Packing or coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6073—Construction of the column body in open tubular form
    • G01N30/6078—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G01N30/7266—Nebulising, aerosol formation or ionisation by electric field, e.g. electrospray

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP2008539439A 2005-11-09 2006-11-09 粒子 Pending JP2009515180A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0502485A SE0502485L (sv) 2005-11-09 2005-11-09 Partiklar
PCT/EP2006/068311 WO2007054548A2 (en) 2005-11-09 2006-11-09 Particles for use in a mobile solid chromatography phase

Publications (2)

Publication Number Publication Date
JP2009515180A true JP2009515180A (ja) 2009-04-09
JP2009515180A5 JP2009515180A5 (https=) 2009-12-17

Family

ID=38015424

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008539439A Pending JP2009515180A (ja) 2005-11-09 2006-11-09 粒子

Country Status (7)

Country Link
US (1) US20090236519A1 (https=)
EP (1) EP1963005B1 (https=)
JP (1) JP2009515180A (https=)
CN (1) CN101336133A (https=)
AT (1) ATE509697T1 (https=)
SE (1) SE0502485L (https=)
WO (1) WO2007054548A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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US7794837B2 (en) 2007-08-06 2010-09-14 The United States of America as represented by the Secretary of Commerce, the National Institute of Standards and Technology Covalently immobilized fluorinated carboxylic acid stationary phase for liquid chromatography
WO2009131526A1 (en) * 2008-04-22 2009-10-29 Ge Healthcare Bio-Sciences Ab Chromatography medium
CN102958602A (zh) * 2010-07-09 2013-03-06 通用电气健康护理生物科学股份公司 层析方法及为此使用的介质
CN102847514B (zh) * 2012-09-26 2015-06-17 复旦大学 可用作毛细管电色谱准固定相的纳米介孔材料及其制备方法
US10018635B2 (en) 2014-07-30 2018-07-10 Novilytic, LLC Method for analyzing samples of a biological fluid
JP6409528B2 (ja) * 2014-11-27 2018-10-24 Jnc株式会社 アミノ基を含むイオン交換基とブチル基を含む疎水性基とを有する多孔性セルロース粒子及びそれを含むクロマトグラフィー担体ならびにｂ型肝炎ウィルスのウィルス様粒子の精製方法
CN104741090B (zh) * 2015-03-19 2017-08-29 深圳职业技术学院 一种扩张床吸附(eba)介质和其制备方法
JP7725953B2 (ja) * 2021-09-06 2025-08-20 Jnc株式会社 多孔質粒子とその製造方法、およびこれを用いたクロマトグラフィー用充填剤

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001514745A (ja) * 1997-03-04 2001-09-11 アメルシャム・ファルマシア・バイオテック・アクチボラグ 分離用マトリックスおよび該マトリックスを利用した分離法
JP2002529714A (ja) * 1998-11-09 2002-09-10 イルガム ナット クロマトグラフィー分離法および選択吸着体
JP2004099433A (ja) * 2002-08-22 2004-04-02 Japan Science & Technology Agency 金属イオンで一部置換または表面担持されたリン酸カルシウム多孔質球形粒子とリン酸カルシウム多孔質多層球形粒子
JP2005180938A (ja) * 2003-12-16 2005-07-07 Sumitomo Pharmaceut Co Ltd （１−ヒドロキシエチリデン）ビス−フォスフォネートの分析方法
JP2007510153A (ja) * 2003-10-31 2007-04-19 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 新規分離マトリックス
JP2007522444A (ja) * 2004-01-20 2007-08-09 ポール・コーポレーション 生理的イオン強度でタンパク質を吸着させるためのクロマトグラフィー材料

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Publication number Priority date Publication date Assignee Title
JP2001514745A (ja) * 1997-03-04 2001-09-11 アメルシャム・ファルマシア・バイオテック・アクチボラグ 分離用マトリックスおよび該マトリックスを利用した分離法
JP2002529714A (ja) * 1998-11-09 2002-09-10 イルガム ナット クロマトグラフィー分離法および選択吸着体
JP2004099433A (ja) * 2002-08-22 2004-04-02 Japan Science & Technology Agency 金属イオンで一部置換または表面担持されたリン酸カルシウム多孔質球形粒子とリン酸カルシウム多孔質多層球形粒子
JP2007510153A (ja) * 2003-10-31 2007-04-19 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 新規分離マトリックス
JP2005180938A (ja) * 2003-12-16 2005-07-07 Sumitomo Pharmaceut Co Ltd （１−ヒドロキシエチリデン）ビス−フォスフォネートの分析方法
JP2007522444A (ja) * 2004-01-20 2007-08-09 ポール・コーポレーション 生理的イオン強度でタンパク質を吸着させるためのクロマトグラフィー材料

Also Published As

Publication number Publication date
SE0502485L (sv) 2007-05-10
ATE509697T1 (de) 2011-06-15
WO2007054548A3 (en) 2007-09-20
US20090236519A1 (en) 2009-09-24
CN101336133A (zh) 2008-12-31
WO2007054548A2 (en) 2007-05-18
EP1963005A2 (en) 2008-09-03
EP1963005B1 (en) 2011-05-18

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