JP2009508971A5 - - Google Patents
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- Publication number
- JP2009508971A5 JP2009508971A5 JP2008532411A JP2008532411A JP2009508971A5 JP 2009508971 A5 JP2009508971 A5 JP 2009508971A5 JP 2008532411 A JP2008532411 A JP 2008532411A JP 2008532411 A JP2008532411 A JP 2008532411A JP 2009508971 A5 JP2009508971 A5 JP 2009508971A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- tautomer
- salt
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CC(C(C[C@](C(C(C(C)=C1C=C(C(C)=O)C2=CC(F)=CCC2C(C)=N)=C(C)CC1=N)O)N)OC)(N1CC*CC1)O Chemical compound CC(C(C[C@](C(C(C(C)=C1C=C(C(C)=O)C2=CC(F)=CCC2C(C)=N)=C(C)CC1=N)O)N)OC)(N1CC*CC1)O 0.000 description 4
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71947405P | 2005-09-22 | 2005-09-22 | |
| PCT/US2006/036946 WO2007038251A1 (en) | 2005-09-22 | 2006-09-21 | Alkoxy indolinone based protein kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009508971A JP2009508971A (ja) | 2009-03-05 |
| JP2009508971A5 true JP2009508971A5 (https=) | 2009-11-12 |
Family
ID=37900093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008532411A Withdrawn JP2009508971A (ja) | 2005-09-22 | 2006-09-21 | アルコキシインドリノン系プロテインキナーゼ阻害剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090305382A1 (https=) |
| EP (1) | EP1926725A4 (https=) |
| JP (1) | JP2009508971A (https=) |
| KR (1) | KR20080046701A (https=) |
| CN (1) | CN101282965A (https=) |
| AU (1) | AU2006294600A1 (https=) |
| BR (1) | BRPI0616378A2 (https=) |
| CA (1) | CA2621809A1 (https=) |
| RU (1) | RU2008110083A (https=) |
| WO (1) | WO2007038251A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009508971A (ja) * | 2005-09-22 | 2009-03-05 | ザ スクリプス リサーチ インスティテュート | アルコキシインドリノン系プロテインキナーゼ阻害剤 |
| JP2010502741A (ja) * | 2006-09-11 | 2010-01-28 | キュリス，インコーポレイテッド | Ｐｔｋインヒビターとしての亜鉛結合部分を含む置換２−インドリノン |
| ES2565683T3 (es) * | 2006-09-15 | 2016-04-06 | Xcovery, Inc. | Compuestos inhibidores de quinasa |
| IN2014MN02105A (https=) | 2012-04-20 | 2015-09-11 | Annji Pharm Co Ltd | |
| AU2015226206B2 (en) | 2014-03-07 | 2017-03-16 | F. Hoffmann-La Roche Ag | Novel 6-fused heteroaryldihydropyrimidines for the treatment and prophylaxis of Hepatitis B virus infection |
| CA2979490C (en) | 2015-03-16 | 2023-07-18 | F. Hoffmann-La Roche Ag | Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor |
| EP3512556B1 (en) | 2016-09-13 | 2021-08-18 | F. Hoffmann-La Roche AG | Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor |
| CN110016052B (zh) * | 2018-01-08 | 2021-09-28 | 四川海思科制药有限公司 | N-去乙基舒尼替尼的磷酰胺衍生物及其制备方法 |
| JP2022525522A (ja) | 2019-03-25 | 2022-05-17 | エフ．ホフマン－ラ ロシュ アーゲー | Ｈｂｖコアタンパク質アロステリック修飾剤の化合物の固体形態 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US72934A (en) * | 1867-12-31 | Improvement in marking-gauge fob sswim-mgohines | ||
| AR042586A1 (es) * | 2001-02-15 | 2005-06-29 | Sugen Inc | 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa |
| TWI259081B (en) * | 2001-10-26 | 2006-08-01 | Sugen Inc | Treatment of acute myeloid leukemia with indolinone compounds |
| MXPA06006049A (es) * | 2003-11-26 | 2007-05-24 | Scripps Research Inst | Inhibidores de proteina quinasa avanzados a base de indolinona. |
| JP2009508971A (ja) * | 2005-09-22 | 2009-03-05 | ザ スクリプス リサーチ インスティテュート | アルコキシインドリノン系プロテインキナーゼ阻害剤 |
-
2006
- 2006-09-21 JP JP2008532411A patent/JP2009508971A/ja not_active Withdrawn
- 2006-09-21 CA CA002621809A patent/CA2621809A1/en not_active Abandoned
- 2006-09-21 CN CNA2006800352235A patent/CN101282965A/zh active Pending
- 2006-09-21 EP EP06815164A patent/EP1926725A4/en not_active Withdrawn
- 2006-09-21 WO PCT/US2006/036946 patent/WO2007038251A1/en not_active Ceased
- 2006-09-21 RU RU2008110083/04A patent/RU2008110083A/ru not_active Application Discontinuation
- 2006-09-21 BR BRPI0616378-5A patent/BRPI0616378A2/pt not_active IP Right Cessation
- 2006-09-21 US US11/991,971 patent/US20090305382A1/en not_active Abandoned
- 2006-09-21 KR KR1020087008492A patent/KR20080046701A/ko not_active Withdrawn
- 2006-09-21 AU AU2006294600A patent/AU2006294600A1/en not_active Abandoned
- 2006-09-21 US US11/525,291 patent/US7629339B2/en not_active Expired - Fee Related
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