JP2012510502A5 - - Google Patents
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- Publication number
- JP2012510502A5 JP2012510502A5 JP2011538999A JP2011538999A JP2012510502A5 JP 2012510502 A5 JP2012510502 A5 JP 2012510502A5 JP 2011538999 A JP2011538999 A JP 2011538999A JP 2011538999 A JP2011538999 A JP 2011538999A JP 2012510502 A5 JP2012510502 A5 JP 2012510502A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- pyrrolidine
- compound represented
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08170435.5 | 2008-12-02 | ||
| EP08170435A EP2194048A1 (en) | 2008-12-02 | 2008-12-02 | Nitrate esters for the treatment of vascular and metabolic diseases |
| PCT/EP2009/066159 WO2010063724A1 (en) | 2008-12-02 | 2009-12-01 | Nitrate derivatives of cilostazol for the treatment of vascular and metabolic diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012510502A JP2012510502A (ja) | 2012-05-10 |
| JP2012510502A5 true JP2012510502A5 (https=) | 2013-01-24 |
Family
ID=40456966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011538999A Ceased JP2012510502A (ja) | 2008-12-02 | 2009-12-01 | 血管性及び代謝性疾患の処置のためのシロスタゾールの硝酸エステル誘導体 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8426597B2 (https=) |
| EP (2) | EP2194048A1 (https=) |
| JP (1) | JP2012510502A (https=) |
| KR (1) | KR20110088598A (https=) |
| CN (1) | CN102245583A (https=) |
| AU (1) | AU2009324123A1 (https=) |
| BR (1) | BRPI0923300A2 (https=) |
| CA (1) | CA2745252A1 (https=) |
| IL (1) | IL213214A0 (https=) |
| MX (1) | MX2011005744A (https=) |
| RU (1) | RU2011126607A (https=) |
| SG (1) | SG171423A1 (https=) |
| WO (1) | WO2010063724A1 (https=) |
| ZA (1) | ZA201104011B (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011131613A1 (en) | 2010-04-19 | 2011-10-27 | Cardiolynx Ag | Valsartan derivatives carrying nitrogen oxide donors for the treatment of vascular and metabolic diseases |
| AR081268A1 (es) | 2010-06-02 | 2012-07-18 | Cardiolynx Ag | Derivados de nitrato de pioglitazona |
| ES2691092T3 (es) | 2012-08-21 | 2018-11-23 | Janssen Pharmaceutica Nv | Anticuerpos contra la risperidona y uso de los mismos |
| CN104837838A (zh) | 2012-08-21 | 2015-08-12 | 詹森药业有限公司 | 帕潘立酮半抗原 |
| PL2888592T3 (pl) | 2012-08-21 | 2018-03-30 | Janssen Pharmaceutica Nv | Przeciwciała względem kwetiapiny i ich zastosowania |
| CA2882596C (en) | 2012-08-21 | 2019-05-14 | Ortho-Clinical Diagnostics, Inc. | Antibodies to olanzapine and use thereof |
| WO2014031656A1 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc | Antibodies to olanzapine haptens and use thereof |
| JP6131414B2 (ja) | 2012-08-21 | 2017-05-24 | ヤンセン ファーマシューティカ エヌ．ベー． | アリピプラゾールのハプテン及びイムノアッセイにおけるそれらの使用 |
| CA2882562C (en) | 2012-08-21 | 2019-08-27 | Eric Hryhorenko | Antibodies to aripiprazole and use thereof |
| JP2015527365A (ja) | 2012-08-21 | 2015-09-17 | オルソ−クリニカル ダイアグノスティクス，インコーポレイティド | パリペリドンに対する抗体及びその使用 |
| ES2669565T3 (es) | 2012-08-21 | 2018-05-28 | Janssen Pharmaceutica Nv | Haptenos de risperidona y paliperidona |
| PL2888257T3 (pl) | 2012-08-21 | 2018-02-28 | Janssen Pharmaceutica Nv | Hapteny kwetiapiny do zastosowania w testach immunologicznych |
| JP2015529199A (ja) | 2012-08-21 | 2015-10-05 | オルソ−クリニカル ダイアグノスティクス，インコーポレイティド | パリペリドンハプテンに対する抗体及びその使用 |
| CN104854110B (zh) | 2012-08-21 | 2016-12-28 | 詹森药业有限公司 | 奥氮平半抗原 |
| EP2888284B1 (en) | 2012-08-21 | 2022-07-06 | Janssen Pharmaceutica NV | Antibodies to risperidone haptens and use thereof |
| JP6389176B2 (ja) | 2012-08-21 | 2018-09-12 | ヤンセン ファーマシューティカ エヌ．ベー． | アリピプラゾールハプテンに対する抗体及びその使用 |
| JP6450314B2 (ja) | 2012-08-21 | 2019-01-09 | ヤンセン ファーマシューティカ エヌ．ベー． | クエチアピンハプテンに対する抗体及びその使用 |
| EP3390449A1 (en) | 2015-12-17 | 2018-10-24 | Janssen Pharmaceutica N.V. | Antibodies to risperidone and use thereof |
| US10435478B2 (en) | 2015-12-17 | 2019-10-08 | Janssen Pharmaceutica Nv | Antibodies to quetiapine and use thereof |
| CN114044766B (zh) * | 2021-10-09 | 2022-12-27 | 张北北九食品检验技术有限公司 | 放射性同位素碳-14标记的呋虫胺和中间体及其制备方法和应用 |
| CN120441542B (zh) * | 2025-05-08 | 2025-09-30 | 安徽益普克医药科技发展有限公司 | 一种西洛他唑衍生物及其制备方法与用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535019A (en) | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| DE122007000050I1 (de) | 1990-02-19 | 2007-11-08 | Novartis Ag | Acylverbindungen |
| US6148496A (en) | 1999-04-09 | 2000-11-21 | The Procter & Gamble Company | Method for making a seamless apertured metal belt |
| IT1311924B1 (it) | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| PL379420A1 (pl) | 2003-07-31 | 2006-09-04 | Nicox S.A. | Pochodne blokerów receptora angiotensyny II |
| WO2006079610A1 (en) * | 2005-01-31 | 2006-08-03 | Nicox S.A. | Nitrooxy sartan derivatives as angiotensin ii receptor blockers for the treatment of cardiovascular and inflammatory diseases |
| EP1922069A2 (en) * | 2005-08-08 | 2008-05-21 | Nitromed, Inc. | Nitric oxide enhancing angiotensin ii antagonist compounds, compositions and methods of use |
-
2008
- 2008-12-02 EP EP08170435A patent/EP2194048A1/en not_active Withdrawn
-
2009
- 2009-12-01 BR BRPI0923300A patent/BRPI0923300A2/pt not_active Application Discontinuation
- 2009-12-01 EP EP09793498A patent/EP2367803A1/en not_active Withdrawn
- 2009-12-01 MX MX2011005744A patent/MX2011005744A/es not_active Application Discontinuation
- 2009-12-01 KR KR1020117015258A patent/KR20110088598A/ko not_active Withdrawn
- 2009-12-01 RU RU2011126607/04A patent/RU2011126607A/ru unknown
- 2009-12-01 US US13/131,722 patent/US8426597B2/en not_active Expired - Fee Related
- 2009-12-01 WO PCT/EP2009/066159 patent/WO2010063724A1/en not_active Ceased
- 2009-12-01 CA CA2745252A patent/CA2745252A1/en not_active Abandoned
- 2009-12-01 JP JP2011538999A patent/JP2012510502A/ja not_active Ceased
- 2009-12-01 SG SG2011038213A patent/SG171423A1/en unknown
- 2009-12-01 CN CN200980149072XA patent/CN102245583A/zh active Pending
- 2009-12-01 AU AU2009324123A patent/AU2009324123A1/en not_active Abandoned
-
2011
- 2011-05-30 IL IL213214A patent/IL213214A0/en unknown
- 2011-05-31 ZA ZA2011/04011A patent/ZA201104011B/en unknown
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