CN101282965A - 基于烷氧基吲哚酮的蛋白激酶抑制剂 - Google Patents
基于烷氧基吲哚酮的蛋白激酶抑制剂 Download PDFInfo
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- CN101282965A CN101282965A CNA2006800352235A CN200680035223A CN101282965A CN 101282965 A CN101282965 A CN 101282965A CN A2006800352235 A CNA2006800352235 A CN A2006800352235A CN 200680035223 A CN200680035223 A CN 200680035223A CN 101282965 A CN101282965 A CN 101282965A
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71947405P | 2005-09-22 | 2005-09-22 | |
| US60/719,474 | 2005-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101282965A true CN101282965A (zh) | 2008-10-08 |
Family
ID=37900093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006800352235A Pending CN101282965A (zh) | 2005-09-22 | 2006-09-21 | 基于烷氧基吲哚酮的蛋白激酶抑制剂 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090305382A1 (https=) |
| EP (1) | EP1926725A4 (https=) |
| JP (1) | JP2009508971A (https=) |
| KR (1) | KR20080046701A (https=) |
| CN (1) | CN101282965A (https=) |
| AU (1) | AU2006294600A1 (https=) |
| BR (1) | BRPI0616378A2 (https=) |
| CA (1) | CA2621809A1 (https=) |
| RU (1) | RU2008110083A (https=) |
| WO (1) | WO2007038251A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110016052A (zh) * | 2018-01-08 | 2019-07-16 | 四川海思科制药有限公司 | N-去乙基舒尼替尼的磷酰胺衍生物及其制备方法 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009508971A (ja) * | 2005-09-22 | 2009-03-05 | ザ スクリプス リサーチ インスティテュート | アルコキシインドリノン系プロテインキナーゼ阻害剤 |
| JP2010502741A (ja) * | 2006-09-11 | 2010-01-28 | キュリス，インコーポレイテッド | Ｐｔｋインヒビターとしての亜鉛結合部分を含む置換２−インドリノン |
| ES2565683T3 (es) * | 2006-09-15 | 2016-04-06 | Xcovery, Inc. | Compuestos inhibidores de quinasa |
| IN2014MN02105A (https=) | 2012-04-20 | 2015-09-11 | Annji Pharm Co Ltd | |
| AU2015226206B2 (en) | 2014-03-07 | 2017-03-16 | F. Hoffmann-La Roche Ag | Novel 6-fused heteroaryldihydropyrimidines for the treatment and prophylaxis of Hepatitis B virus infection |
| CA2979490C (en) | 2015-03-16 | 2023-07-18 | F. Hoffmann-La Roche Ag | Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor |
| EP3512556B1 (en) | 2016-09-13 | 2021-08-18 | F. Hoffmann-La Roche AG | Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor |
| JP2022525522A (ja) | 2019-03-25 | 2022-05-17 | エフ．ホフマン－ラ ロシュ アーゲー | Ｈｂｖコアタンパク質アロステリック修飾剤の化合物の固体形態 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US72934A (en) * | 1867-12-31 | Improvement in marking-gauge fob sswim-mgohines | ||
| AR042586A1 (es) * | 2001-02-15 | 2005-06-29 | Sugen Inc | 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa |
| TWI259081B (en) * | 2001-10-26 | 2006-08-01 | Sugen Inc | Treatment of acute myeloid leukemia with indolinone compounds |
| MXPA06006049A (es) * | 2003-11-26 | 2007-05-24 | Scripps Research Inst | Inhibidores de proteina quinasa avanzados a base de indolinona. |
| JP2009508971A (ja) * | 2005-09-22 | 2009-03-05 | ザ スクリプス リサーチ インスティテュート | アルコキシインドリノン系プロテインキナーゼ阻害剤 |
-
2006
- 2006-09-21 JP JP2008532411A patent/JP2009508971A/ja not_active Withdrawn
- 2006-09-21 CA CA002621809A patent/CA2621809A1/en not_active Abandoned
- 2006-09-21 CN CNA2006800352235A patent/CN101282965A/zh active Pending
- 2006-09-21 EP EP06815164A patent/EP1926725A4/en not_active Withdrawn
- 2006-09-21 WO PCT/US2006/036946 patent/WO2007038251A1/en not_active Ceased
- 2006-09-21 RU RU2008110083/04A patent/RU2008110083A/ru not_active Application Discontinuation
- 2006-09-21 BR BRPI0616378-5A patent/BRPI0616378A2/pt not_active IP Right Cessation
- 2006-09-21 US US11/991,971 patent/US20090305382A1/en not_active Abandoned
- 2006-09-21 KR KR1020087008492A patent/KR20080046701A/ko not_active Withdrawn
- 2006-09-21 AU AU2006294600A patent/AU2006294600A1/en not_active Abandoned
- 2006-09-21 US US11/525,291 patent/US7629339B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110016052A (zh) * | 2018-01-08 | 2019-07-16 | 四川海思科制药有限公司 | N-去乙基舒尼替尼的磷酰胺衍生物及其制备方法 |
| CN110016052B (zh) * | 2018-01-08 | 2021-09-28 | 四川海思科制药有限公司 | N-去乙基舒尼替尼的磷酰胺衍生物及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006294600A1 (en) | 2007-04-05 |
| WO2007038251A1 (en) | 2007-04-05 |
| BRPI0616378A2 (pt) | 2011-06-21 |
| CA2621809A1 (en) | 2007-04-05 |
| EP1926725A4 (en) | 2010-10-06 |
| EP1926725A1 (en) | 2008-06-04 |
| US7629339B2 (en) | 2009-12-08 |
| US20070072934A1 (en) | 2007-03-29 |
| JP2009508971A (ja) | 2009-03-05 |
| KR20080046701A (ko) | 2008-05-27 |
| US20090305382A1 (en) | 2009-12-10 |
| RU2008110083A (ru) | 2009-10-27 |
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Open date: 20081008 |