JP2009502800A5 - - Google Patents

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Publication number
JP2009502800A5
JP2009502800A5 JP2008522947A JP2008522947A JP2009502800A5 JP 2009502800 A5 JP2009502800 A5 JP 2009502800A5 JP 2008522947 A JP2008522947 A JP 2008522947A JP 2008522947 A JP2008522947 A JP 2008522947A JP 2009502800 A5 JP2009502800 A5 JP 2009502800A5
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JP
Japan
Prior art keywords
pharmaceutical composition
polyethylene glycol
polypeptide
seq
encoded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008522947A
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English (en)
Japanese (ja)
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JP4987001B2 (ja
JP2009502800A (ja
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Publication date
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Priority claimed from PCT/US2006/028106 external-priority patent/WO2007013944A2/en
Publication of JP2009502800A publication Critical patent/JP2009502800A/ja
Publication of JP2009502800A5 publication Critical patent/JP2009502800A5/ja
Application granted granted Critical
Publication of JP4987001B2 publication Critical patent/JP4987001B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008522947A 2005-07-20 2006-07-20 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 Active JP4987001B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US70095105P 2005-07-20 2005-07-20
US60/700,951 2005-07-20
US77126006P 2006-02-08 2006-02-08
US60/771,260 2006-02-08
PCT/US2006/028106 WO2007013944A2 (en) 2005-07-20 2006-07-20 Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders

Publications (3)

Publication Number Publication Date
JP2009502800A JP2009502800A (ja) 2009-01-29
JP2009502800A5 true JP2009502800A5 (enExample) 2009-09-03
JP4987001B2 JP4987001B2 (ja) 2012-07-25

Family

ID=37683787

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008522947A Active JP4987001B2 (ja) 2005-07-20 2006-07-20 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法

Country Status (7)

Country Link
US (5) US20070020227A1 (enExample)
EP (1) EP1909821A2 (enExample)
JP (1) JP4987001B2 (enExample)
AU (1) AU2006272937A1 (enExample)
CA (1) CA2616004A1 (enExample)
IL (1) IL188357A0 (enExample)
WO (1) WO2007013944A2 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
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AU2001271786A1 (en) * 2000-06-30 2002-01-14 Zymogenetics Inc. Interferon-like protein zcyto21
US7038032B2 (en) 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
EP2251353B1 (en) * 2003-08-07 2013-03-06 ZymoGenetics, Inc. Homogeneous preparations of IL-29
EP1912668A2 (en) * 2005-07-20 2008-04-23 ZymoGenetics, Inc. Il28 and il29 truncated cysteine mutants and antiviral methods of using same
AU2006272937A1 (en) * 2005-07-20 2007-02-01 Bristol-Myers Squibb Company Use of truncated cysteine IL28 and IL29 mutants to treat cancers and autoimmune disorders
EP1931704B1 (en) 2005-10-04 2010-12-15 ZymoGenetics, L.L.C. Production and purification of il-29
JP2009115776A (ja) * 2007-07-11 2009-05-28 Ngk Spark Plug Co Ltd アンモニアガスセンサ
JP5083898B2 (ja) * 2007-07-11 2012-11-28 日本特殊陶業株式会社 アンモニアガスセンサ
RU2496514C2 (ru) * 2008-06-05 2013-10-27 Займоджинетикс, Инк. Применение пэгилированных интерферонов типа iii для лечения гепатита с
US20100316608A1 (en) * 2009-06-15 2010-12-16 Vijayaprakash Suppiah Method of Determining A Response To Treatment With Immunomodulatory Composition
FR2975185A1 (fr) * 2011-05-12 2012-11-16 Univ Claude Bernard Lyon Procede de determination in vitro de la presence d'une sclerose en plaques
CN104045704B (zh) * 2013-03-11 2016-08-10 中国医学科学院基础医学研究所 PEG化重组人IFN-λ1、其制备方法和用途
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
CN103923209B (zh) * 2014-05-13 2016-06-22 北京凯因科技股份有限公司 一种Lambda干扰素突变体及聚乙二醇衍生物
CN105085658B (zh) * 2014-05-14 2019-12-24 杭州先为达生物科技有限公司 一种白细胞介素29突变体及聚乙二醇衍生物
DE102015001902A1 (de) * 2015-02-18 2016-08-18 Continental Reifen Deutschland Gmbh Verfahren zur Verbesserung der Haftung zwischen einem Verstärkungselement und einem elastomeren Matrixmaterial
CN107530338B (zh) 2015-04-21 2020-12-01 艾格尔峰生物制药有限公司 包含洛那法尼和利托那韦的药物组合物
KR20180110127A (ko) 2016-02-19 2018-10-08 아이거 바이오파마슈티컬스 인코포레이티드 인터페론 람다를 이용한 델타 간염 바이러스 감염의 치료
JP2019531729A (ja) * 2016-09-30 2019-11-07 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 変異体iii型インターフェロン及びシンセカイン
US20220378878A1 (en) * 2019-12-20 2022-12-01 The Council Of The Queensland Institute Of Medical Research Treatment of gastrointestinal disease
KR102226826B1 (ko) * 2020-08-06 2021-03-11 주식회사 휴벳바이오 버피 코트 시료에 사용하기 위한 췌장암 진단용 조성물

Family Cites Families (20)

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FI86558C (fi) 1980-01-08 1992-09-10 Biogen Inc Dna- sekvenser, rekombinant-dna- molekyler och foerfaranden foer framstaellning av humant interferon av -typ och val av dna-sekvensen.
US4853332A (en) * 1982-10-19 1989-08-01 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of biologically active proteins
US5206344A (en) * 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US6468776B1 (en) * 2000-03-03 2002-10-22 Zymogenetics, Inc. Human serine protease
AU2001271589A1 (en) * 2000-06-30 2002-01-14 Zymogenetics Inc. Mammalian secreted proteins
AU2001271786A1 (en) * 2000-06-30 2002-01-14 Zymogenetics Inc. Interferon-like protein zcyto21
EP2298789B1 (en) 2000-09-08 2012-03-14 Schering Corporation Mammalian genes; related reagents and methods
US7038032B2 (en) * 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
CN100482684C (zh) * 2001-04-20 2009-04-29 津莫吉尼蒂克斯公司 细胞因子蛋白质家族
PL373008A1 (en) * 2001-05-10 2005-08-08 Immunex Corporation Cytokine polypeptides
WO2003066002A2 (en) * 2002-02-08 2003-08-14 University Of Medicine And Dentistry Of New Jersey IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION
BR0309401A (pt) * 2002-04-19 2007-02-21 Zymogenetics Inc polinucleotìdeo isolado, vetor de expressão, célula cultivada, método para produzir polipeptìdeos, e um anticorpo para um polipeptìdeo, e, anticorpo
EP1575609A4 (en) 2002-10-23 2010-12-15 Zymogenetics L L C METHOD FOR THE TREATMENT OF VIRUS INFECTIONS USING IL-28 AND IL-29
EP2251353B1 (en) * 2003-08-07 2013-03-06 ZymoGenetics, Inc. Homogeneous preparations of IL-29
CA2558829C (en) 2004-04-02 2014-03-11 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29 cysteine mutants
AU2005266892B2 (en) * 2004-07-29 2011-03-03 Bristol-Myers Squibb Company Use of IL-28 and IL-29 to treat cancer and autoimmune disorders
CN1305902C (zh) 2004-11-25 2007-03-21 汕头大学医学院 一种人白细胞介素29的生产方法及重组il-29工程菌
AU2006272937A1 (en) * 2005-07-20 2007-02-01 Bristol-Myers Squibb Company Use of truncated cysteine IL28 and IL29 mutants to treat cancers and autoimmune disorders
EP1912668A2 (en) * 2005-07-20 2008-04-23 ZymoGenetics, Inc. Il28 and il29 truncated cysteine mutants and antiviral methods of using same
EP1931704B1 (en) * 2005-10-04 2010-12-15 ZymoGenetics, L.L.C. Production and purification of il-29

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