JP2006006329A5 - - Google Patents

Download PDF

Info

Publication number
JP2006006329A5
JP2006006329A5 JP2005180188A JP2005180188A JP2006006329A5 JP 2006006329 A5 JP2006006329 A5 JP 2006006329A5 JP 2005180188 A JP2005180188 A JP 2005180188A JP 2005180188 A JP2005180188 A JP 2005180188A JP 2006006329 A5 JP2006006329 A5 JP 2006006329A5
Authority
JP
Japan
Prior art keywords
agonist
antagonist
admixture
seq
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2005180188A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006006329A (ja
JP4358159B2 (ja
Filing date
Publication date
Priority claimed from PCT/US1998/025108 external-priority patent/WO1999028462A2/en
Priority claimed from PCT/US1999/005028 external-priority patent/WO1999046281A2/en
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/en
Priority claimed from PCT/US1999/020111 external-priority patent/WO2000012708A2/en
Priority claimed from PCT/US1999/020594 external-priority patent/WO2000015666A2/en
Priority claimed from PCT/US1999/020944 external-priority patent/WO2000015792A2/en
Priority claimed from PCT/US1999/021090 external-priority patent/WO2000015796A2/en
Priority claimed from PCT/US1999/021547 external-priority patent/WO2000015797A2/en
Priority claimed from PCT/US1999/023089 external-priority patent/WO2000021996A2/en
Application filed filed Critical
Publication of JP2006006329A publication Critical patent/JP2006006329A/ja
Publication of JP2006006329A5 publication Critical patent/JP2006006329A5/ja
Publication of JP4358159B2 publication Critical patent/JP4358159B2/ja
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2005180188A 1998-12-01 2005-06-21 血管形成及び心臓血管新生の促進又は阻害 Expired - Lifetime JP4358159B2 (ja)

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
PCT/US1998/025108 WO1999028462A2 (en) 1997-12-03 1998-12-01 Polypeptides and nucleic acids encoding the same
US11285098P 1998-12-16 1998-12-16
US11555499P 1999-01-12 1999-01-12
PCT/US1999/005028 WO1999046281A2 (en) 1998-03-10 1999-03-08 Novel polypeptides and nucleic acids encoding the same
US12395799P 1999-03-12 1999-03-12
US13144599P 1999-04-28 1999-04-28
US13428799P 1999-05-14 1999-05-14
PCT/US1999/012252 WO1999063088A2 (en) 1998-06-02 1999-06-02 Membrane-bound proteins and nucleic acids encoding the same
US14103799P 1999-06-23 1999-06-23
US14475899P 1999-07-20 1999-07-20
US14569899P 1999-07-26 1999-07-26
PCT/US1999/020111 WO2000012708A2 (en) 1998-09-01 1999-09-01 Further pro polypeptides and sequences thereof
PCT/US1999/020594 WO2000015666A2 (en) 1998-09-10 1999-09-08 Compositions and methods for the treatment of tumors
PCT/US1999/020944 WO2000015792A2 (en) 1998-09-14 1999-09-13 Promotion or inhibition of angiogenesis and cardiovascularization
PCT/US1999/021547 WO2000015797A2 (en) 1998-09-17 1999-09-15 Compositions and methods for the treatment of immune related diseases
PCT/US1999/021090 WO2000015796A2 (en) 1998-09-16 1999-09-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US1999/023089 WO2000021996A2 (en) 1998-10-13 1999-10-05 Methods and compositions for inhibiting neoplastic cell growth
US16250699P 1999-10-29 1999-10-29

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2004212340A Division JP3803681B2 (ja) 1998-12-01 2004-07-20 血管形成及び心臓血管新生の促進又は阻害

Publications (3)

Publication Number Publication Date
JP2006006329A JP2006006329A (ja) 2006-01-12
JP2006006329A5 true JP2006006329A5 (enExample) 2007-01-18
JP4358159B2 JP4358159B2 (ja) 2009-11-04

Family

ID=37398593

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000584912A Expired - Fee Related JP3695642B2 (ja) 1998-12-01 1999-11-30 血管形成及び心臓血管新生の促進又は阻害
JP2004212340A Expired - Lifetime JP3803681B2 (ja) 1998-12-01 2004-07-20 血管形成及び心臓血管新生の促進又は阻害
JP2005180188A Expired - Lifetime JP4358159B2 (ja) 1998-12-01 2005-06-21 血管形成及び心臓血管新生の促進又は阻害

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2000584912A Expired - Fee Related JP3695642B2 (ja) 1998-12-01 1999-11-30 血管形成及び心臓血管新生の促進又は阻害
JP2004212340A Expired - Lifetime JP3803681B2 (ja) 1998-12-01 2004-07-20 血管形成及び心臓血管新生の促進又は阻害

Country Status (9)

Country Link
EP (1) EP1135485B1 (enExample)
JP (3) JP3695642B2 (enExample)
KR (1) KR100529270B1 (enExample)
AT (1) ATE458050T1 (enExample)
AU (1) AU771751C (enExample)
CA (1) CA2347835A1 (enExample)
IL (1) IL202176A0 (enExample)
MX (1) MXPA01005169A (enExample)
WO (1) WO2000032221A2 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001019991A1 (en) * 1999-09-15 2001-03-22 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
DE69837996T2 (de) 1997-01-14 2008-02-28 Human Genome Sciences, Inc. Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
US7285267B2 (en) 1997-01-14 2007-10-23 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6α & 6β
US20020132252A1 (en) * 1997-06-16 2002-09-19 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO1999014330A1 (en) 1997-09-18 1999-03-25 Genentech, Inc. DcR3 POLYPEPTIDE, A TNFR HOMOLOG
US6689607B2 (en) 1997-10-21 2004-02-10 Human Genome Sciences, Inc. Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
US6503184B1 (en) 1997-10-21 2003-01-07 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
EP1064382B1 (en) 1998-03-17 2008-08-20 Genentech, Inc. Polypeptides homologous to vegf and bmp1
US6949339B1 (en) 1998-05-21 2005-09-27 Diadexus, Inc. Method of diagnosing, monitoring, and staging colon cancer
CA2331154A1 (en) 1998-06-16 1999-12-23 Human Genome Sciences, Inc. Polypeptides having sequence identity with acid labile subunit of insulin-like growth factor
US7014996B1 (en) 1998-10-02 2006-03-21 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating gynecologic cancers
EP1131430B1 (en) 1998-11-10 2007-01-17 Emory University Mitogenic regulators
US6432673B1 (en) 1998-12-07 2002-08-13 Zymogenetics, Inc. Growth factor homolog ZVEGF3
CA2354610A1 (en) * 1998-12-09 2000-06-15 Shionogi & Co., Ltd. Human secretory phospholipase a2
EP1710299A3 (en) * 1998-12-30 2007-01-10 Millennium Pharmaceuticals, Inc. Secreted proteins and nucleic acids encoding them
JP2003531811A (ja) * 1999-03-08 2003-10-28 ジェネンテック・インコーポレーテッド 血管形成及び心臓血管新生の促進又は阻害
CA2366087A1 (en) * 1999-03-11 2000-09-14 Mount Sinai Hospital Sialic acid-binding ig-like lectin (siglec) gene; ob-binding protein like (ob-bpl)
AU3737500A (en) * 1999-03-12 2000-09-28 Genentech Inc. Method of preventing the death of retinal neurons and treating ocular diseases
ATE376837T1 (de) * 1999-07-12 2007-11-15 Genentech Inc Stimulierung oder hemmung von angiogenese und herzvaskularisierung mit tumor nekrose faktor ligand/rezeptor homologen
ATE368110T1 (de) * 1999-07-20 2007-08-15 Genentech Inc Zusammensetzung und verfahren zur behandlung von immunverwandten krankheiten
HUP0203408A3 (en) * 1999-12-09 2005-01-28 Sankyo Co Method of testing remedy or preventive for hyperlipemia
US7119165B2 (en) 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
HUP0203863A3 (en) * 2000-01-12 2008-03-28 Univ Yale Nogo receptor-mediated blockade of axonal growth
WO2001064856A2 (en) * 2000-02-28 2001-09-07 The Government Of The United States Of America, A S Represented By The Secretary, Department Of Hea Lth And Human Services Regulators of type-1 tumor necrosis factor receptor and other cytokine receptor shedding
AU4880901A (en) 2000-04-21 2001-11-07 Takeda Chemical Industries Ltd Novel insulin/igf/relaxin family polypeptides and dnas thereof
CA2416538A1 (en) * 2000-07-20 2002-01-31 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
ES2341608T3 (es) 2000-10-06 2010-06-23 Yale University Homologos del receptor de nogo.
US20020111302A1 (en) * 2000-11-30 2002-08-15 Y. Tom Tang Novel nucleic acids and polypeptides
JPWO2002057448A1 (ja) * 2000-12-27 2004-05-20 第一ファインケミカル株式会社 新規ペプチド及びその活性
EP1573024A4 (en) 2001-04-10 2007-08-29 Agensys Inc NUCLEIC ACIDS AND SUITABLE PROTEINS SUITABLE FOR THE TREATMENT AND EVIDENCE OF VARIOUS CANCER DISEASES
WO2003006687A2 (en) * 2001-07-10 2003-01-23 Medigene Ag Novel target genes for diseases of the heart
WO2003053334A2 (en) * 2001-12-19 2003-07-03 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
JP2006501812A (ja) * 2002-03-01 2006-01-19 ブラッド センター リサーチ フオンデーシヨン Ｋｕ−７０由来のｂａｘ抑制ペプチド類および損傷細胞を保護するためのその使用
CA2480419A1 (en) * 2002-03-28 2003-10-09 Yamanouchi Pharmaceutical Co., Ltd. Antiopoietin-related growth factor
WO2004002515A1 (ja) * 2002-06-28 2004-01-08 Takeda Chemical Industries, Ltd. 呼吸器疾患の診断・予防・治療剤
ATE469913T1 (de) 2002-08-10 2010-06-15 Univ Yale Antagonisten des nogo-rezeptors
WO2005068497A1 (en) * 2004-01-06 2005-07-28 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Iis: a novel ifn-gamma-inducible protein, member of the secretoglobin family, that modulates cellular invasion and migration
EP1904091A4 (en) 2005-07-07 2009-12-23 Univ Yale COMPOSITIONS AND METHODS FOR SUPPRESSING THE INHIBITION OF AXON GROWTH
PL3151921T3 (pl) 2014-06-06 2020-02-28 Bristol-Myers Squibb Company Przeciwciała przeciwko receptorowi indukowanego glukokortykoidami czynnika martwicy nowotworu (gitr) i ich zastosowania
EP3304079B1 (en) 2015-06-03 2020-06-03 Bristol-Myers Squibb Company Anti-gitr antibodies for cancer diagnostics
MX2018006072A (es) 2015-11-19 2018-08-01 Squibb Bristol Myers Co Anticuerpos contra receptor de factor de necrosis de tumor inducido por glucocorticoides (gitr) y usos de los mismos.
WO2018213297A1 (en) 2017-05-16 2018-11-22 Bristol-Myers Squibb Company Treatment of cancer with anti-gitr agonist antibodies
CN109136275B (zh) * 2017-06-19 2021-03-16 百奥赛图(北京)医药科技股份有限公司 人源化gitr基因改造动物模型的制备方法及应用
CN114507677B (zh) * 2022-02-16 2023-09-05 中国人民解放军空军军医大学 Ndufs1基因在治疗心梗后心衰中的应用和相关产品
EP4484444A1 (en) * 2023-06-28 2025-01-01 Centre National de la Recherche Scientifique Protein and fragments thereof, and their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900673A (en) * 1988-03-28 1990-02-13 President And Fellows Of Harvard College Mutant human angiogenin (angiogenesis factor with superior angiogenin activity) genes therefor and methods of expression
EP0646178A1 (en) 1992-06-04 1995-04-05 The Regents Of The University Of California expression cassette with regularoty regions functional in the mammmlian host
CN1636594B (zh) * 1994-04-26 2012-08-29 儿童医学中心公司 血管生成抑制素和用于抑制血管生成的方法
US5681746A (en) 1994-12-30 1997-10-28 Chiron Viagene, Inc. Retroviral delivery of full length factor VIII
EP0861894B1 (en) * 1995-11-17 2006-03-08 Asahi Kasei Kabushiki Kaisha Differentiation-suppressive polypeptide

Similar Documents

Publication Publication Date Title
ZA200706030B (en) GLP-1 agonists, compositions, methods and uses
DE602005010109D1 (de) 1,1a,5,5a-tetrahydro-3-thia-cyclopropaäaüpentaleneptor-agonisten
JP2008514563A5 (enExample)
IL199680A0 (en) Piperidine gpcr agonists, compositions comprising the same, processes for producing ths same and uses thereof
JP2003292804A5 (enExample)
IL195580A (en) L – fkbp polypeptides, preparations containing them, methods of preparation and use
IL188799A0 (en) Substituted tetrahydro-1h-pyrido[4,3,b]indoles as serotonin receptor agonists and antagonists
JP2007508034A5 (enExample)
JP2007525988A5 (enExample)
EP2003091A4 (en) SUBSTRATE WITH MICROFINES MOUNTED ON THE SURFACE METAL LUBRICATION
IL185926A (en) Annals of 2 - (3,1-Dihydro-H2-Benzimidazole-2-Illiden) -1-Alkylamidinosulfonylphenyl-3 - (Phenyl or Thienyl) -Propane-3,1
ATE362488T1 (de) Agonisten des corticotropin-freisetzenden faktor rezeptors 2
CL2007003198A1 (es) Compuestos diarilicos opcionalmente nitrogenados, antagonistas de los receptores opioides; composicion farmaceutica; y uso en el tratamiento de la obesidad.
FR2891314B1 (fr) Bras d'injecteur anti-cokefaction.
JP2010510994A5 (enExample)
JP2004529205A5 (enExample)
NZ592670A (en) Corticotrophin releasing hormone receptor 2 peptide agonists and uses thereof
EP1848731A4 (en) ANTIBIOTIC 107891, THEIR FACTORS A1 AND A2, PHARMACEUTICALLY SALTS AND COMPOSITIONS, AND THE APPLICATION THEREOF
JP2009155218A5 (enExample)
JP2005531640A5 (enExample)
DE602006018617D1 (de) Pharmazeutische zusammensetzung mit 2,3-dihydro-6-nitroimidazoä2,1-büoxazolderivaten
LV The gray correlative analysis on environmental factors affecting mortality of tilapia during wintering
RU2004132147A (ru) Адаптоген
SI1855705T1 (sl) Antibiotik njegovi faktorji farmacevtskosprejemljive soli in sestavi in njihova uporaba
ITRM20040242A1 (it) "7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine.