JP4987001B2 - 癌および自己免疫障害を処置するためのｉｌ２８およびｉｌ２９の短縮型システイン変異体の使用法 - Google Patents

癌および自己免疫障害を処置するためのｉｌ２８およびｉｌ２９の短縮型システイン変異体の使用法 Download PDF

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JP4987001B2
JP4987001B2 JP2008522947A JP2008522947A JP4987001B2 JP 4987001 B2 JP4987001 B2 JP 4987001B2 JP 2008522947 A JP2008522947 A JP 2008522947A JP 2008522947 A JP2008522947 A JP 2008522947A JP 4987001 B2 JP4987001 B2 JP 4987001B2
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ポール オー． シェパード
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ザイモジェネティクス リミテッド ライアビリティ カンパニー
ブリストル−マイヤーズ スクウィブ カンパニー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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  • Animal Behavior & Ethology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
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  • Toxicology (AREA)
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  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2008522947A 2005-07-20 2006-07-20 癌および自己免疫障害を処置するためのｉｌ２８およびｉｌ２９の短縮型システイン変異体の使用法 Expired - Lifetime JP4987001B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US70095105P 2005-07-20 2005-07-20
US60/700,951 2005-07-20
US77126006P 2006-02-08 2006-02-08
US60/771,260 2006-02-08
PCT/US2006/028106 WO2007013944A2 (en) 2005-07-20 2006-07-20 Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders

Publications (3)

Publication Number Publication Date
JP2009502800A JP2009502800A (ja) 2009-01-29
JP2009502800A5 JP2009502800A5 (enExample) 2009-09-03
JP4987001B2 true JP4987001B2 (ja) 2012-07-25

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JP2008522947A Expired - Lifetime JP4987001B2 (ja) 2005-07-20 2006-07-20 癌および自己免疫障害を処置するためのｉｌ２８およびｉｌ２９の短縮型システイン変異体の使用法

Country Status (7)

Country Link
US (5) US20070020227A1 (enExample)
EP (1) EP1909821A2 (enExample)
JP (1) JP4987001B2 (enExample)
AU (1) AU2006272937A1 (enExample)
CA (1) CA2616004A1 (enExample)
IL (1) IL188357A0 (enExample)
WO (1) WO2007013944A2 (enExample)

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ES2286128T3 (es) * 2000-06-30 2007-12-01 Zymogenetics, Inc. Proteina zcyto21 tipo interferon.
US7038032B2 (en) 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
JP4808157B2 (ja) 2003-08-07 2011-11-02 ザイモジェネティクス リミテッド ライアビリティ カンパニー Ｉｌ−２８およびｉｌ−２９の均一な調製物
EP1909821A2 (en) * 2005-07-20 2008-04-16 ZymoGenetics, Inc. Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders
JP2009502803A (ja) * 2005-07-20 2009-01-29 ザイモジェネティクス， インコーポレイテッド Ｉｌ−２８およびｉｌ−２９のシステイン欠失変異体、ならびにそれを用いる抗ウイルス法
JP5364375B2 (ja) * 2005-10-04 2013-12-11 ザイモジェネティクス リミテッド ライアビリティ カンパニー Ｉｌ−２９の生産および精製の方法
JP5083898B2 (ja) * 2007-07-11 2012-11-28 日本特殊陶業株式会社 アンモニアガスセンサ
JP2009115776A (ja) * 2007-07-11 2009-05-28 Ngk Spark Plug Co Ltd アンモニアガスセンサ
RU2496514C2 (ru) * 2008-06-05 2013-10-27 Займоджинетикс, Инк. Применение пэгилированных интерферонов типа iii для лечения гепатита с
US20100316608A1 (en) * 2009-06-15 2010-12-16 Vijayaprakash Suppiah Method of Determining A Response To Treatment With Immunomodulatory Composition
FR2975185A1 (fr) * 2011-05-12 2012-11-16 Univ Claude Bernard Lyon Procede de determination in vitro de la presence d'une sclerose en plaques
CN104045704B (zh) * 2013-03-11 2016-08-10 中国医学科学院基础医学研究所 PEG化重组人IFN-λ1、其制备方法和用途
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
CN103923209B (zh) * 2014-05-13 2016-06-22 北京凯因科技股份有限公司 一种Lambda干扰素突变体及聚乙二醇衍生物
CN105085658B (zh) * 2014-05-14 2019-12-24 杭州先为达生物科技有限公司 一种白细胞介素29突变体及聚乙二醇衍生物
DE102015001902A1 (de) * 2015-02-18 2016-08-18 Continental Reifen Deutschland Gmbh Verfahren zur Verbesserung der Haftung zwischen einem Verstärkungselement und einem elastomeren Matrixmaterial
HUE054068T2 (hu) 2015-04-21 2021-08-30 Eiger Biopharmaceuticals Inc Lonafarnibot és Ritonavirt tartalmazó gyógyszerkészítmények
RS61944B1 (sr) 2016-02-19 2021-07-30 Eiger Biopharmaceuticals Inc Lečenje infekcije hepatitis delta virusom sa interferonom lambda
US11198717B2 (en) * 2016-09-30 2021-12-14 The Board Of Trustees Of The Leland Stanford Junior University Variant type III interferons and synthekines
WO2021119749A1 (en) * 2019-12-20 2021-06-24 The Council Of The Queensland Institute Of Medical Research Treatment of gastrointestinal disease
GB202003595D0 (en) * 2020-03-12 2020-04-29 Ilc Therapeutics Ltd Compositions and methods relating to the treatment of diseases
KR102226826B1 (ko) * 2020-08-06 2021-03-11 주식회사 휴벳바이오 버피 코트 시료에 사용하기 위한 췌장암 진단용 조성물

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JP2009502803A (ja) * 2005-07-20 2009-01-29 ザイモジェネティクス， インコーポレイテッド Ｉｌ−２８およびｉｌ−２９のシステイン欠失変異体、ならびにそれを用いる抗ウイルス法
JP5364375B2 (ja) * 2005-10-04 2013-12-11 ザイモジェネティクス リミテッド ライアビリティ カンパニー Ｉｌ−２９の生産および精製の方法

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Publication number Publication date
EP1909821A2 (en) 2008-04-16
US20140044676A1 (en) 2014-02-13
IL188357A0 (en) 2008-04-13
US8313739B2 (en) 2012-11-20
WO2007013944A3 (en) 2007-05-18
JP2009502800A (ja) 2009-01-29
WO2007013944A2 (en) 2007-02-01
US20070020227A1 (en) 2007-01-25
US20110177024A1 (en) 2011-07-21
US20120251488A1 (en) 2012-10-04
AU2006272937A1 (en) 2007-02-01
US20100298230A1 (en) 2010-11-25
CA2616004A1 (en) 2007-02-01
AU2006272937A8 (en) 2008-02-28

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