JP2009500611A5 - - Google Patents
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- JP2009500611A5 JP2009500611A5 JP2008519721A JP2008519721A JP2009500611A5 JP 2009500611 A5 JP2009500611 A5 JP 2009500611A5 JP 2008519721 A JP2008519721 A JP 2008519721A JP 2008519721 A JP2008519721 A JP 2008519721A JP 2009500611 A5 JP2009500611 A5 JP 2009500611A5
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- JP
- Japan
- Prior art keywords
- pdz
- agent
- seq
- protein
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000034 method Methods 0.000 claims 40
- 229920001184 polypeptide Polymers 0.000 claims 26
- 102000004196 processed proteins & peptides Human genes 0.000 claims 26
- 108090000765 processed proteins & peptides Proteins 0.000 claims 26
- 101710128560 Initiator protein NS1 Proteins 0.000 claims 24
- 101710144127 Non-structural protein 1 Proteins 0.000 claims 24
- 239000003795 chemical substances by application Substances 0.000 claims 23
- 241000712431 Influenza A virus Species 0.000 claims 16
- 108700019745 Disks Large Homolog 4 Proteins 0.000 claims 15
- 102100022264 Disks large homolog 4 Human genes 0.000 claims 15
- 101150069842 dlg4 gene Proteins 0.000 claims 11
- 239000000523 sample Substances 0.000 claims 10
- 238000001514 detection method Methods 0.000 claims 8
- 230000027455 binding Effects 0.000 claims 7
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 230000009870 specific binding Effects 0.000 claims 7
- 239000003153 chemical reaction reagent Substances 0.000 claims 6
- 102100024099 Disks large homolog 1 Human genes 0.000 claims 4
- 101001053984 Homo sapiens Disks large homolog 1 Proteins 0.000 claims 4
- 101000951365 Homo sapiens Disks large-associated protein 5 Proteins 0.000 claims 4
- 101000599573 Homo sapiens InaD-like protein Proteins 0.000 claims 4
- 102100037978 InaD-like protein Human genes 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- 102100024117 Disks large homolog 2 Human genes 0.000 claims 3
- 101001053980 Homo sapiens Disks large homolog 2 Proteins 0.000 claims 3
- 101000590691 Homo sapiens MAGUK p55 subfamily member 2 Proteins 0.000 claims 3
- 241001500351 Influenzavirus A Species 0.000 claims 3
- 229940024606 amino acid Drugs 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 238000003556 assay Methods 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 3
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- 101100457021 Caenorhabditis elegans mag-1 gene Proteins 0.000 claims 2
- 101001018300 Homo sapiens Microtubule-associated serine/threonine-protein kinase 2 Proteins 0.000 claims 2
- 101150080421 MAGI1 gene Proteins 0.000 claims 2
- 102100033253 Microtubule-associated serine/threonine-protein kinase 2 Human genes 0.000 claims 2
- 101100067996 Mus musculus Gbp1 gene Proteins 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102100026882 Alpha-synuclein Human genes 0.000 claims 1
- 102100036514 Amyloid-beta A4 precursor protein-binding family A member 1 Human genes 0.000 claims 1
- 102100036440 Amyloid-beta A4 precursor protein-binding family A member 3 Human genes 0.000 claims 1
- 101150058381 Apba3 gene Proteins 0.000 claims 1
- 241000271566 Aves Species 0.000 claims 1
- 102100022258 Disks large homolog 5 Human genes 0.000 claims 1
- 241000283086 Equidae Species 0.000 claims 1
- 102100032844 Gamma-1-syntrophin Human genes 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 101000928690 Homo sapiens Amyloid-beta A4 precursor protein-binding family A member 1 Proteins 0.000 claims 1
- 101000902114 Homo sapiens Disks large homolog 5 Proteins 0.000 claims 1
- 101000868448 Homo sapiens Gamma-1-syntrophin Proteins 0.000 claims 1
- 101001005128 Homo sapiens LIM domain kinase 1 Proteins 0.000 claims 1
- 101000969697 Homo sapiens Multiple PDZ domain protein Proteins 0.000 claims 1
- 101000848727 Homo sapiens Rap guanine nucleotide exchange factor 2 Proteins 0.000 claims 1
- 101001087422 Homo sapiens Tyrosine-protein phosphatase non-receptor type 13 Proteins 0.000 claims 1
- 208000002979 Influenza in Birds Diseases 0.000 claims 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
- 102100026023 LIM domain kinase 1 Human genes 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- ZJTJUVIJVLLGSP-UHFFFAOYSA-N Lumichrome Natural products N1C(=O)NC(=O)C2=C1N=C1C=C(C)C(C)=CC1=N2 ZJTJUVIJVLLGSP-UHFFFAOYSA-N 0.000 claims 1
- 101150074715 MAGI3 gene Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 102100021286 Multiple PDZ domain protein Human genes 0.000 claims 1
- 108010008858 Nitric Oxide Synthase Type I Proteins 0.000 claims 1
- 102100022397 Nitric oxide synthase, brain Human genes 0.000 claims 1
- 206010036790 Productive cough Diseases 0.000 claims 1
- 102100034585 Rap guanine nucleotide exchange factor 2 Human genes 0.000 claims 1
- 102100032735 SH3 and multiple ankyrin repeat domains protein 1 Human genes 0.000 claims 1
- 101710101742 SH3 and multiple ankyrin repeat domains protein 1 Proteins 0.000 claims 1
- 102100030680 SH3 and multiple ankyrin repeat domains protein 2 Human genes 0.000 claims 1
- 102100030681 SH3 and multiple ankyrin repeat domains protein 3 Human genes 0.000 claims 1
- 101710101741 SH3 and multiple ankyrin repeat domains protein 3 Proteins 0.000 claims 1
- 101710067890 SHANK2 Proteins 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 241000282887 Suidae Species 0.000 claims 1
- 102100037219 Syntenin-1 Human genes 0.000 claims 1
- 108010083130 Syntenins Proteins 0.000 claims 1
- 102000004402 Syntrophin Human genes 0.000 claims 1
- 108090000916 Syntrophin Proteins 0.000 claims 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- 241000216217 Turkish sheep encephalitis virus Species 0.000 claims 1
- 102100033014 Tyrosine-protein phosphatase non-receptor type 13 Human genes 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 206010064097 avian influenza Diseases 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 210000000416 exudates and transudate Anatomy 0.000 claims 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 1
- 239000010931 gold Substances 0.000 claims 1
- 229910052737 gold Inorganic materials 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- 239000004816 latex Substances 0.000 claims 1
- 229920000126 latex Polymers 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 235000021110 pickles Nutrition 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
- 125000000341 threoninyl group Chemical group [H]OC([H])(C([H])([H])[H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 241000712461 unidentified influenza virus Species 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69622105P | 2005-07-01 | 2005-07-01 | |
| US72637705P | 2005-10-13 | 2005-10-13 | |
| US76529206P | 2006-02-02 | 2006-02-02 | |
| US79227406P | 2006-04-14 | 2006-04-14 | |
| PCT/US2006/026155 WO2007018843A2 (en) | 2005-07-01 | 2006-07-03 | Methods and compositions for diagnosis and treatment of influenza |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009500611A JP2009500611A (ja) | 2009-01-08 |
| JP2009500611A5 true JP2009500611A5 (enExample) | 2009-08-20 |
Family
ID=37307088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008519721A Pending JP2009500611A (ja) | 2005-07-01 | 2006-07-03 | インフルエンザの診断および治療のための方法および組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7595151B2 (enExample) |
| EP (1) | EP1910837B1 (enExample) |
| JP (1) | JP2009500611A (enExample) |
| AT (1) | ATE549624T1 (enExample) |
| AU (1) | AU2006276813A1 (enExample) |
| CA (1) | CA2613482A1 (enExample) |
| IL (1) | IL188460A (enExample) |
| WO (1) | WO2007018843A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7595297B2 (en) * | 1999-06-02 | 2009-09-29 | Michael Tymianski | Method of reducing injury to mammalian cells |
| US7510824B2 (en) * | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| DE10254601A1 (de) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| DE102004024617A1 (de) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| US7595152B2 (en) * | 2005-07-01 | 2009-09-29 | Arbor Vita Corporation | Detection of influenza virus |
| CA2613482A1 (en) * | 2005-07-01 | 2007-02-15 | Arbor Vita Corporation | Methods and compositions for diagnosis and treatment of influenza |
| EP1790664A1 (en) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer |
| EP2215450B1 (en) * | 2006-02-21 | 2013-07-31 | Nexus DX, Inc. | Methods and compositions for analyte detection |
| US20100028855A1 (en) * | 2006-10-21 | 2010-02-04 | Arbor Vista Corporation | Detection of influenza virus type b |
| RU2337703C1 (ru) * | 2007-03-06 | 2008-11-10 | Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) | Средство профилактики и лечения вирусных заболеваний и способ профилактики и лечения вирусных заболеваний |
| MX2010000578A (es) * | 2007-07-17 | 2010-04-30 | Somalogic Inc | Metodo para generar aptameros con constantes de disociacion mejoradas. |
| WO2009015384A1 (en) * | 2007-07-26 | 2009-01-29 | University Of Rochester | Nucleic acid binding compounds and methods of use |
| WO2009117362A1 (en) * | 2008-03-15 | 2009-09-24 | Arbor Vita Corporation | Ns1-np diagnostics of influenza virus infection |
| CN101649356B (zh) * | 2009-07-24 | 2012-09-05 | 浙江省疾病预防控制中心 | 甲型h1n1流感病毒荧光定量检测试剂盒及检测方法 |
| KR101341640B1 (ko) * | 2010-02-05 | 2013-12-16 | 한국전자통신연구원 | 단백질 미세 구조 분석 방법 및 단백질 미세 구조 분석용 어레이 |
| WO2011146825A2 (en) * | 2010-05-20 | 2011-11-24 | The Board Of Trustees Of The University Of Arkansas | Avian influenza h5n1 specific aptamers and their use |
| US9217137B2 (en) * | 2011-08-12 | 2015-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for specific regulation of pyruvate dehydrogenase kinase |
| US9416391B2 (en) | 2011-11-18 | 2016-08-16 | Thelial Technologies S.A. | Method for identifying cancer drug candidates in Drosophila |
| CA2861543C (en) | 2012-01-18 | 2022-05-31 | Governing Council Of The University Of Toronto | Novel peptides and methods and uses thereof for preventing retinal disorders |
| WO2013167153A1 (en) | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
| KR101471245B1 (ko) * | 2012-05-31 | 2014-12-10 | 충북대학교 산학협력단 | Ａ형 인플루엔자 바이러스 감염 질환의 예방 및 치료용 조성물 |
| US9493542B2 (en) * | 2013-02-22 | 2016-11-15 | Augusta University Research Institute, Inc. | Methods of using ERBB2 conjugate peptides |
| US20140329706A1 (en) * | 2013-05-01 | 2014-11-06 | California Institute Of Technology | Affinity tags, and related affinity ligands, engineered proteins, modified supports, compositions, methods and systems |
| JP2018128408A (ja) * | 2017-02-10 | 2018-08-16 | 東ソー株式会社 | 抗体凝集体形成予測方法 |
| US20220236272A1 (en) * | 2019-06-13 | 2022-07-28 | Fundació Hospital Universitari Vall D'hebron - Institut De Recerca | Synthrocyte: erythrocyte-mimicking reagent and fast methods for pathogen characterization and serology testing |
| US11549114B2 (en) * | 2020-03-27 | 2023-01-10 | Apollo Biomedical, LLC | Multiple rapid detection kits and methods for various viruses |
| WO2021188569A1 (en) * | 2020-03-17 | 2021-09-23 | Detect, Inc. | Rapid diagnostic test with blister pack |
| CN111410694B (zh) * | 2020-03-27 | 2020-12-22 | 浙江省人民医院 | 一种抗胶质瘤的多肽分子及其应用 |
| WO2022018622A1 (en) * | 2020-07-20 | 2022-01-27 | United Arab Emirates University | Method and system for virus and protein-antibody interactions detection and monitoring based on optical light intensity and electrical parameters |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO870613L (no) | 1986-03-05 | 1987-09-07 | Molecular Diagnostics Inc | Deteksjon av mikroorganismer i en prve inneholdende nukleinsyre. |
| AU620330B2 (en) | 1987-05-29 | 1992-02-20 | Smithkline Beckman Corporation | Immunodiagnostic assays using chimeric antigens |
| DE68928853T2 (de) | 1988-05-20 | 1999-08-05 | Cetus Corp., Emeryville, Calif. | Befestigung von sequenzspezifischen proben |
| US5856092A (en) | 1989-02-13 | 1999-01-05 | Geneco Pty Ltd | Detection of a nucleic acid sequence or a change therein |
| CA2084307A1 (en) | 1990-06-01 | 1991-12-02 | Cetus Oncology Corporation | Compositions and methods for identifying biologically active molecules |
| US5846710A (en) | 1990-11-02 | 1998-12-08 | St. Louis University | Method for the detection of genetic diseases and gene sequence variations by single nucleotide primer extension |
| US6004744A (en) | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
| US5888819A (en) | 1991-03-05 | 1999-03-30 | Molecular Tool, Inc. | Method for determining nucleotide identity through primer extension |
| GB9502489D0 (en) * | 1995-02-09 | 1995-03-29 | Animal Health Trust | Expression of the non-structural protein NS1 of influenza virus and detection of anti-NS1 antibody in serum |
| WO2002007751A1 (en) | 2000-07-25 | 2002-01-31 | Axcell Biosciences Corporation | Identification and isolation of novel polypeptides having pdz domains and methods of using same |
| US7312041B2 (en) * | 2001-02-16 | 2007-12-25 | Arbor Vita Corporation | Methods of diagnosing cervical cancer |
| JP4426122B2 (ja) * | 2001-01-23 | 2010-03-03 | 株式会社ビーエル | 血中抗原検出方法及び装置 |
| US20030119203A1 (en) * | 2001-12-24 | 2003-06-26 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay devices and methods for conducting assays |
| EP1537415B1 (en) * | 2002-09-09 | 2008-12-17 | Arbor Vita Corporation | Methods of diagnosing cervical cancer |
| JP2004161685A (ja) * | 2002-11-14 | 2004-06-10 | Bl:Kk | 卵黄関連蛋白およびその用途 |
| JP2004166564A (ja) * | 2002-11-19 | 2004-06-17 | Bl:Kk | モノクローナル抗体および結核症診断法 |
| JP4933258B2 (ja) * | 2003-09-22 | 2012-05-16 | クイデル コーポレーション | 試料中の複数分析物の検出装置 |
| JP2006067979A (ja) | 2004-09-06 | 2006-03-16 | Bl:Kk | インフルエンザａ型ウイルスの免疫検出法 |
| US7595152B2 (en) * | 2005-07-01 | 2009-09-29 | Arbor Vita Corporation | Detection of influenza virus |
| CA2613482A1 (en) * | 2005-07-01 | 2007-02-15 | Arbor Vita Corporation | Methods and compositions for diagnosis and treatment of influenza |
| CN101323501B (zh) * | 2007-01-02 | 2015-10-07 | 德雷卡通信技术公司 | 用于石英玻璃沉积管的连续焙烧方法 |
-
2006
- 2006-07-03 CA CA002613482A patent/CA2613482A1/en not_active Abandoned
- 2006-07-03 US US11/481,411 patent/US7595151B2/en active Active - Reinstated
- 2006-07-03 WO PCT/US2006/026155 patent/WO2007018843A2/en not_active Ceased
- 2006-07-03 AT AT06786341T patent/ATE549624T1/de active
- 2006-07-03 JP JP2008519721A patent/JP2009500611A/ja active Pending
- 2006-07-03 AU AU2006276813A patent/AU2006276813A1/en not_active Abandoned
- 2006-07-03 EP EP06786341A patent/EP1910837B1/en not_active Not-in-force
-
2007
- 2007-12-27 IL IL188460A patent/IL188460A/en not_active IP Right Cessation
-
2009
- 2009-08-11 US US12/539,535 patent/US20100112547A1/en not_active Abandoned
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