CA2613482A1 - Methods and compositions for diagnosis and treatment of influenza - Google Patents

Methods and compositions for diagnosis and treatment of influenza Download PDF

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Publication number
CA2613482A1
CA2613482A1 CA002613482A CA2613482A CA2613482A1 CA 2613482 A1 CA2613482 A1 CA 2613482A1 CA 002613482 A CA002613482 A CA 002613482A CA 2613482 A CA2613482 A CA 2613482A CA 2613482 A1 CA2613482 A1 CA 2613482A1
Authority
CA
Canada
Prior art keywords
pdz
seq
protein
influenza
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002613482A
Other languages
English (en)
French (fr)
Inventor
Peter S. Lu
Joshua D. Rabinowitz
Michael P. Belmares
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arbor Vita Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2613482A1 publication Critical patent/CA2613482A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1019Tetrapeptides with the first amino acid being basic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1021Tetrapeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/11Orthomyxoviridae, e.g. influenza virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002613482A 2005-07-01 2006-07-03 Methods and compositions for diagnosis and treatment of influenza Abandoned CA2613482A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US69622105P 2005-07-01 2005-07-01
US60/696,221 2005-07-01
US72637705P 2005-10-13 2005-10-13
US60/726,377 2005-10-13
US76529206P 2006-02-02 2006-02-02
US60/765,292 2006-02-02
US79227406P 2006-04-14 2006-04-14
US60/792,274 2006-04-14
PCT/US2006/026155 WO2007018843A2 (en) 2005-07-01 2006-07-03 Methods and compositions for diagnosis and treatment of influenza

Publications (1)

Publication Number Publication Date
CA2613482A1 true CA2613482A1 (en) 2007-02-15

Family

ID=37307088

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002613482A Abandoned CA2613482A1 (en) 2005-07-01 2006-07-03 Methods and compositions for diagnosis and treatment of influenza

Country Status (8)

Country Link
US (2) US7595151B2 (enExample)
EP (1) EP1910837B1 (enExample)
JP (1) JP2009500611A (enExample)
AT (1) ATE549624T1 (enExample)
AU (1) AU2006276813A1 (enExample)
CA (1) CA2613482A1 (enExample)
IL (1) IL188460A (enExample)
WO (1) WO2007018843A2 (enExample)

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US7595297B2 (en) * 1999-06-02 2009-09-29 Michael Tymianski Method of reducing injury to mammalian cells
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
US7595152B2 (en) * 2005-07-01 2009-09-29 Arbor Vita Corporation Detection of influenza virus
EP1910837B1 (en) * 2005-07-01 2012-03-14 Arbor Vita Corporation Methods and compositions for diagnosis and treatment of influenza
EP1790664A1 (en) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
EP2215450B1 (en) * 2006-02-21 2013-07-31 Nexus DX, Inc. Methods and compositions for analyte detection
US20100028855A1 (en) * 2006-10-21 2010-02-04 Arbor Vista Corporation Detection of influenza virus type b
RU2337703C1 (ru) * 2007-03-06 2008-11-10 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Средство профилактики и лечения вирусных заболеваний и способ профилактики и лечения вирусных заболеваний
CA3022666C (en) * 2007-07-17 2022-04-19 Somalogic, Inc. Multiplexed analyses of test samples
US9212205B2 (en) 2007-07-26 2015-12-15 University Of Rochester Nucleic acid binding compounds and methods of use
US8163474B2 (en) * 2008-03-15 2012-04-24 Arbor Vita Corporation NS1-NP diagnostics of influenza virus infection
CN101649356B (zh) * 2009-07-24 2012-09-05 浙江省疾病预防控制中心 甲型h1n1流感病毒荧光定量检测试剂盒及检测方法
KR101341640B1 (ko) * 2010-02-05 2013-12-16 한국전자통신연구원 단백질 미세 구조 분석 방법 및 단백질 미세 구조 분석용 어레이
WO2011146825A2 (en) * 2010-05-20 2011-11-24 The Board Of Trustees Of The University Of Arkansas Avian influenza h5n1 specific aptamers and their use
EP2742057B1 (en) * 2011-08-12 2016-04-20 The Board of Trustees of The Leland Stanford Junior University Compositions and methods for specific regulation of pyruvate dehydrogenase kinase
CA2796520A1 (en) 2011-11-18 2013-05-18 Thelial Technologies S.A. Method for identifying cancer drug candidates in drosophila
US9428550B2 (en) 2012-01-18 2016-08-30 Governing Council Of The University Of Toronto Peptides and methods and uses thereof for preventing retinal disorders
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
KR101471245B1 (ko) * 2012-05-31 2014-12-10 충북대학교 산학협력단 A형 인플루엔자 바이러스 감염 질환의 예방 및 치료용 조성물
US9493542B2 (en) * 2013-02-22 2016-11-15 Augusta University Research Institute, Inc. Methods of using ERBB2 conjugate peptides
US20140329706A1 (en) * 2013-05-01 2014-11-06 California Institute Of Technology Affinity tags, and related affinity ligands, engineered proteins, modified supports, compositions, methods and systems
JP2018128408A (ja) * 2017-02-10 2018-08-16 東ソー株式会社 抗体凝集体形成予測方法
EP3983804B1 (en) * 2019-06-13 2025-08-06 Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca Synthrocyte: erythrocyte-mimicking reagent and fast methods for pathogen characterization and serology testing
US11549114B2 (en) * 2020-03-27 2023-01-10 Apollo Biomedical, LLC Multiple rapid detection kits and methods for various viruses
WO2021188569A1 (en) * 2020-03-17 2021-09-23 Detect, Inc. Rapid diagnostic test with blister pack
CN111410694B (zh) * 2020-03-27 2020-12-22 浙江省人民医院 一种抗胶质瘤的多肽分子及其应用
US11493514B2 (en) * 2020-07-20 2022-11-08 United Arab Emirates University Method and system for virus and protein-antibody interactions detection and monitoring based on optical light intensity and electrical parameters

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Also Published As

Publication number Publication date
WO2007018843A3 (en) 2007-06-28
US20100112547A1 (en) 2010-05-06
IL188460A (en) 2012-02-29
WO2007018843A2 (en) 2007-02-15
EP1910837A2 (en) 2008-04-16
US20070161078A1 (en) 2007-07-12
HK1115192A1 (en) 2008-11-21
JP2009500611A (ja) 2009-01-08
IL188460A0 (en) 2008-04-13
EP1910837B1 (en) 2012-03-14
ATE549624T1 (de) 2012-03-15
US7595151B2 (en) 2009-09-29
AU2006276813A1 (en) 2007-02-15

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Legal Events

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EEER Examination request
FZDE Discontinued

Effective date: 20150616