JP2009500611A - インフルエンザの診断および治療のための方法および組成物 - Google Patents

インフルエンザの診断および治療のための方法および組成物 Download PDF

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JP2009500611A
JP2009500611A JP2008519721A JP2008519721A JP2009500611A JP 2009500611 A JP2009500611 A JP 2009500611A JP 2008519721 A JP2008519721 A JP 2008519721A JP 2008519721 A JP2008519721 A JP 2008519721A JP 2009500611 A JP2009500611 A JP 2009500611A
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pdz
seq
protein
influenza
binding
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JP2009500611A5 (enExample
Inventor
ピーター エス． ルー
ジョシュア ディー． ラビノビッツ
マイケル ピー． ベルマレス
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アルボー ビータ コーポレーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/11—Orthomyxoviridae, e.g. influenza virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2008519721A 2005-07-01 2006-07-03 インフルエンザの診断および治療のための方法および組成物 Pending JP2009500611A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US69622105P 2005-07-01 2005-07-01
US72637705P 2005-10-13 2005-10-13
US76529206P 2006-02-02 2006-02-02
US79227406P 2006-04-14 2006-04-14
PCT/US2006/026155 WO2007018843A2 (en) 2005-07-01 2006-07-03 Methods and compositions for diagnosis and treatment of influenza

Publications (2)

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JP2009500611A true JP2009500611A (ja) 2009-01-08
JP2009500611A5 JP2009500611A5 (enExample) 2009-08-20

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US (2) US7595151B2 (enExample)
EP (1) EP1910837B1 (enExample)
JP (1) JP2009500611A (enExample)
AT (1) ATE549624T1 (enExample)
AU (1) AU2006276813A1 (enExample)
CA (1) CA2613482A1 (enExample)
IL (1) IL188460A (enExample)
WO (1) WO2007018843A2 (enExample)

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JP2018128408A (ja) * 2017-02-10 2018-08-16 東ソー株式会社 抗体凝集体形成予測方法

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US7595152B2 (en) * 2005-07-01 2009-09-29 Arbor Vita Corporation Detection of influenza virus
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US9212205B2 (en) 2007-07-26 2015-12-15 University Of Rochester Nucleic acid binding compounds and methods of use
US8163474B2 (en) * 2008-03-15 2012-04-24 Arbor Vita Corporation NS1-NP diagnostics of influenza virus infection
CN101649356B (zh) * 2009-07-24 2012-09-05 浙江省疾病预防控制中心 甲型h1n1流感病毒荧光定量检测试剂盒及检测方法
KR101341640B1 (ko) * 2010-02-05 2013-12-16 한국전자통신연구원 단백질 미세 구조 분석 방법 및 단백질 미세 구조 분석용 어레이
WO2011146825A2 (en) * 2010-05-20 2011-11-24 The Board Of Trustees Of The University Of Arkansas Avian influenza h5n1 specific aptamers and their use
EP2742057B1 (en) * 2011-08-12 2016-04-20 The Board of Trustees of The Leland Stanford Junior University Compositions and methods for specific regulation of pyruvate dehydrogenase kinase
CA2796520A1 (en) 2011-11-18 2013-05-18 Thelial Technologies S.A. Method for identifying cancer drug candidates in drosophila
US9428550B2 (en) 2012-01-18 2016-08-30 Governing Council Of The University Of Toronto Peptides and methods and uses thereof for preventing retinal disorders
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
KR101471245B1 (ko) * 2012-05-31 2014-12-10 충북대학교 산학협력단 Ａ형 인플루엔자 바이러스 감염 질환의 예방 및 치료용 조성물
US9493542B2 (en) * 2013-02-22 2016-11-15 Augusta University Research Institute, Inc. Methods of using ERBB2 conjugate peptides
US20140329706A1 (en) * 2013-05-01 2014-11-06 California Institute Of Technology Affinity tags, and related affinity ligands, engineered proteins, modified supports, compositions, methods and systems
EP3983804B1 (en) * 2019-06-13 2025-08-06 Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca Synthrocyte: erythrocyte-mimicking reagent and fast methods for pathogen characterization and serology testing
US11549114B2 (en) * 2020-03-27 2023-01-10 Apollo Biomedical, LLC Multiple rapid detection kits and methods for various viruses
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CN111410694B (zh) * 2020-03-27 2020-12-22 浙江省人民医院 一种抗胶质瘤的多肽分子及其应用
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Publication number Publication date
WO2007018843A3 (en) 2007-06-28
US20100112547A1 (en) 2010-05-06
IL188460A (en) 2012-02-29
WO2007018843A2 (en) 2007-02-15
EP1910837A2 (en) 2008-04-16
US20070161078A1 (en) 2007-07-12
HK1115192A1 (en) 2008-11-21
IL188460A0 (en) 2008-04-13
CA2613482A1 (en) 2007-02-15
EP1910837B1 (en) 2012-03-14
ATE549624T1 (de) 2012-03-15
US7595151B2 (en) 2009-09-29
AU2006276813A1 (en) 2007-02-15

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