JP2009500427A5 - - Google Patents
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- Publication number
- JP2009500427A5 JP2009500427A5 JP2008520417A JP2008520417A JP2009500427A5 JP 2009500427 A5 JP2009500427 A5 JP 2009500427A5 JP 2008520417 A JP2008520417 A JP 2008520417A JP 2008520417 A JP2008520417 A JP 2008520417A JP 2009500427 A5 JP2009500427 A5 JP 2009500427A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- disease
- treating
- medical condition
- melanocortin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69777905P | 2005-07-08 | 2005-07-08 | |
| US60/697,779 | 2005-07-08 | ||
| US74885005P | 2005-12-09 | 2005-12-09 | |
| US60/748,850 | 2005-12-09 | ||
| PCT/US2006/026586 WO2007008704A2 (en) | 2005-07-08 | 2006-07-10 | Melanocortin receptor ligands |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009263603A Division JP5889513B2 (ja) | 2005-07-08 | 2009-11-19 | メラノコルチン受容体リガンド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009500427A JP2009500427A (ja) | 2009-01-08 |
| JP2009500427A5 true JP2009500427A5 (OSRAM) | 2010-01-21 |
| JP4734411B2 JP4734411B2 (ja) | 2011-07-27 |
Family
ID=37637790
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008520417A Active JP4734411B2 (ja) | 2005-07-08 | 2006-07-10 | メラノコルチン受容体リガンド |
| JP2009263603A Active JP5889513B2 (ja) | 2005-07-08 | 2009-11-19 | メラノコルチン受容体リガンド |
| JP2013165312A Pending JP2013253090A (ja) | 2005-07-08 | 2013-08-08 | メラノコルチン受容体リガンド |
| JP2015140154A Active JP5965520B2 (ja) | 2005-07-08 | 2015-07-14 | メラノコルチン受容体リガンド |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009263603A Active JP5889513B2 (ja) | 2005-07-08 | 2009-11-19 | メラノコルチン受容体リガンド |
| JP2013165312A Pending JP2013253090A (ja) | 2005-07-08 | 2013-08-08 | メラノコルチン受容体リガンド |
| JP2015140154A Active JP5965520B2 (ja) | 2005-07-08 | 2015-07-14 | メラノコルチン受容体リガンド |
Country Status (20)
| Country | Link |
|---|---|
| US (8) | US8039435B2 (OSRAM) |
| EP (6) | EP2548568B1 (OSRAM) |
| JP (4) | JP4734411B2 (OSRAM) |
| KR (2) | KR100997177B1 (OSRAM) |
| CN (5) | CN101257916B (OSRAM) |
| AU (2) | AU2006269261B2 (OSRAM) |
| CA (4) | CA2793119C (OSRAM) |
| DK (4) | DK2236151T3 (OSRAM) |
| ES (4) | ES2663916T3 (OSRAM) |
| FR (1) | FR21C1060I2 (OSRAM) |
| HU (4) | HUE055154T2 (OSRAM) |
| IL (3) | IL188545A (OSRAM) |
| NL (1) | NL301150I2 (OSRAM) |
| NZ (2) | NZ565217A (OSRAM) |
| PL (4) | PL2548568T3 (OSRAM) |
| PT (4) | PT3354273T (OSRAM) |
| RU (2) | RU2439079C2 (OSRAM) |
| SG (1) | SG163585A1 (OSRAM) |
| SI (1) | SI3354273T1 (OSRAM) |
| WO (1) | WO2007008704A2 (OSRAM) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2548568B1 (en) * | 2005-07-08 | 2018-01-10 | Ipsen Pharma | Melanocortin receptor ligands |
| DE102007020152A1 (de) * | 2007-04-26 | 2008-10-30 | Charité - Universitätsmedizin Berlin | Mittel zur antiinfektiven Behandlung eines Patienten |
| TWI364290B (en) | 2007-05-25 | 2012-05-21 | Ipsen Pharma Sas | Melanocortin receptor ligands modifled with hydantoin |
| TW200848424A (en) * | 2007-06-15 | 2008-12-16 | Sod Conseils Rech Applic | Cyclic peptide melanocortin receptor ligands |
| CN103316345B (zh) * | 2007-11-05 | 2016-05-18 | 益普生制药股份有限公司 | 黑皮质素治疗胰岛素敏感的应用 |
| BRPI0912141A2 (pt) | 2008-05-27 | 2016-07-26 | Genzyme Corp | análogos de peptídeo do hormônio alfa-melanócito estimulante |
| EP2300036B1 (en) | 2008-06-09 | 2017-04-05 | Palatin Technologies, Inc. | Melanocortin receptor-specific peptides for treatment of sexual dysfunction |
| NZ596617A (en) * | 2009-06-08 | 2014-04-30 | Palatin Technologies Inc | Melanocortin receptor-specific peptides |
| UY32690A (es) | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
| EP2440572B1 (en) | 2009-06-08 | 2017-04-05 | Palatin Technologies, Inc. | Lactam-bridged melanocortin receptor-specific peptides |
| JP2013501053A (ja) * | 2009-08-05 | 2013-01-10 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | 脂質異常症を治療するためのメラノコルチンの使用 |
| US8541545B2 (en) * | 2009-08-31 | 2013-09-24 | Tensive Controls Inc. | Stabilized melanocortin ligands |
| RU2548753C2 (ru) * | 2009-11-16 | 2015-04-20 | Ипсен Фарма С.А.С. | Фармацевтические композиции лигандов рецепторов меланокортинов |
| US20120226018A1 (en) * | 2009-11-16 | 2012-09-06 | Ipsen Pharma, S.A.S. | Process for the Synthesis of Ac-Arg-Cyclo(Cys-D-Ala-His-D-Phe-Arg-Trp-Cys)-NH2 |
| CA2781405A1 (en) | 2009-11-23 | 2011-05-26 | Palatin Technologies, Inc. | Melanocortin-1 receptor-specific linear peptides |
| NZ599774A (en) | 2009-11-23 | 2014-11-28 | Palatin Technologies Inc | Melanocortin-1 receptor-specific cyclic peptides |
| KR102038677B1 (ko) * | 2011-06-14 | 2019-10-30 | 입센 파마 에스.에이.에스 | 활성 성분으로 멜라노코르틴 수용체 리간드를 함유하는 지속-방출형 조성물 |
| ES2732077T3 (es) | 2011-12-29 | 2019-11-20 | Rhythm Pharmaceuticals Inc | Método para tratar trastornos asociados con el receptor de melanocortina-4 en portadores heterocigotos |
| EP2705835A1 (en) | 2012-06-08 | 2014-03-12 | Ipsen Pharma S.A.S. | Aqueous gelling compositions of soluble active pharmaceutical peptides providing modified release |
| RU2668791C2 (ru) | 2012-10-19 | 2018-10-02 | ТиЭксПи ФАРМА ГМБХ | АНАЛОГИ АЛЬФА- и ГАММА-MSH |
| EP2968475A2 (en) | 2013-03-14 | 2016-01-20 | Questcor Pharmaceuticals, Inc. | Acth for treatment of acute respiratory distress syndrome |
| CN118240012A (zh) * | 2013-03-15 | 2024-06-25 | 节奏制药公司 | 肽组合物 |
| EP2970389B1 (en) | 2013-03-15 | 2020-08-19 | Rhythm Pharmaceuticals, Inc. | Pharmaceutical compositions |
| CN106232623A (zh) | 2014-04-22 | 2016-12-14 | Txp制药股份有限公司 | 具有支链氨基酸探针的肽类似物 |
| ES2985734T3 (es) | 2015-09-30 | 2024-11-07 | Rhythm Pharmaceuticals Inc | Método de tratamiento de trastornos asociados a la vía del receptor de la melanocortina-4 |
| US10653743B2 (en) * | 2015-10-15 | 2020-05-19 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for the treatment of depression and anxiety by a melanocortin 5 receptor antagonist, PG-20N |
| US11542302B2 (en) | 2015-10-15 | 2023-01-03 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Modulators of melanocortin receptors for the treatment of depression and anxiety |
| US20190255142A1 (en) * | 2016-10-17 | 2019-08-22 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Novel modulators of melanocortin receptors for the treatment of depression and anxiety |
| EP3596107A1 (en) * | 2017-03-15 | 2020-01-22 | Novo Nordisk A/S | Bicyclic compounds capable of binding to melanocortin 4 receptor |
| AU2019249255A1 (en) | 2018-04-06 | 2020-11-05 | Alastair GARFIELD | Compositions for treating kidney disease |
| US20210221867A1 (en) * | 2018-05-15 | 2021-07-22 | Novo Nordisk A/S | Compounds Capable of Binding to Melanocortin 4 Receptor |
| WO2019222851A1 (en) * | 2018-05-23 | 2019-11-28 | Provincial Health Services Authority | Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy |
| US11396535B2 (en) | 2019-03-01 | 2022-07-26 | Provincial Health Services Authority | Cyclic peptide analogs of melanocortin and amanitin and methods of making such |
| TW202228760A (zh) * | 2020-09-24 | 2022-08-01 | 美商律森製藥股份有限公司 | 治療黑素皮質素-4受體路徑相關病症之方法 |
| WO2022251650A1 (en) * | 2021-05-27 | 2022-12-01 | The Regents Of The University Of Michigan | Mc3r agonist peptides |
| WO2024083843A1 (en) | 2022-10-18 | 2024-04-25 | Confo Therapeutics N.V. | Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders |
| WO2025123059A1 (en) * | 2023-12-07 | 2025-06-12 | Endevica Bio, Inc. | Non-naturally occurring melanocortin analogs and uses thereof for treating substance use disorders |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US613874A (en) | 1898-11-08 | George e | ||
| US1613874A (en) | 1922-03-29 | 1927-01-11 | Miner Inc W H | Friction draft gear |
| US5652214A (en) | 1989-06-05 | 1997-07-29 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factors and analogs |
| US5672659A (en) | 1993-01-06 | 1997-09-30 | Kinerton Limited | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides |
| US5595760A (en) | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
| US5665702A (en) | 1995-06-06 | 1997-09-09 | Biomeasure Incorporated | Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides |
| US5916883A (en) | 1996-11-01 | 1999-06-29 | Poly-Med, Inc. | Acylated cyclodextrin derivatives |
| SE9700620D0 (sv) | 1997-02-21 | 1997-02-21 | Wapharm Ab | Cykliska peptider med selektivitet för MSH-receptor subtyper |
| WO1999021571A1 (en) | 1997-10-27 | 1999-05-06 | Trega Biosciences, Inc. | Melanocortin receptor ligands and methods of using same |
| US6127381A (en) * | 1998-04-28 | 2000-10-03 | Basu; Amaresh | Isoquinoline compound melanocortin receptor ligands and methods of using same |
| MXPA01001100A (es) * | 1998-07-27 | 2002-08-20 | Univ Iowa State Res Found Inc | Gen del receptor melanocortina-4 y su uso como un marcador genetico para contenido de grasa, ganacia de peso y7o consumo de alimento para animales. |
| AU775289B2 (en) | 1998-08-21 | 2004-07-29 | Children's Medical Center Corporation | Use of melanin for inhibition of angiogenesis and macular degeneration |
| US6603058B1 (en) | 1998-12-09 | 2003-08-05 | Oklahoma Medical Research Foundation | Non-human animal model for obesity and uses thereof |
| US6716810B1 (en) | 1998-12-09 | 2004-04-06 | Eleanor Roosevelt Institute | Composition and method for regulation of body weight and associated conditions |
| CA2368431C (en) * | 1999-03-29 | 2006-01-24 | The Procter & Gamble Company | Melanocortin receptor ligands |
| US6579968B1 (en) * | 1999-06-29 | 2003-06-17 | Palatin Technologies, Inc. | Compositions and methods for treatment of sexual dysfunction |
| US7176279B2 (en) | 2000-06-28 | 2007-02-13 | Palatin Technologies, Inc. | Cyclic peptide compositions and methods for treatment of sexual dysfunction |
| WO2001033954A1 (en) | 1999-11-12 | 2001-05-17 | Merck & Co., Inc. | Melanocortin-3 receptor deficient cells, non-human transgenic animals and methods of selecting compounds which regulate body weight |
| US6600015B2 (en) | 2000-04-04 | 2003-07-29 | Hoffmann-La Roche Inc. | Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity |
| AP2001002196A0 (en) * | 2000-06-28 | 2002-12-21 | Pfizer Prod Inc | Melanocortin receptor ligands. |
| US6720324B2 (en) | 2000-07-05 | 2004-04-13 | Synaptic Pharmaceutical Corporation | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof |
| MXPA03002160A (es) | 2000-09-13 | 2004-05-04 | Eleanor Roosevelt Inst | Metodo para el tratamiento de resistencia a insulina en obesidad y diabetes. |
| US20030113263A1 (en) | 2001-02-13 | 2003-06-19 | Oregon Health And Sciences University, A Non-Profit Organization | Methods and reagents for using mammalian melanocortin receptor antagonists to treat cachexia |
| CA2437594A1 (en) | 2001-03-02 | 2002-09-12 | Graham S. Poindexter | Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same |
| US6770645B2 (en) * | 2001-03-16 | 2004-08-03 | Pfizer Inc. | Pharmaceutically active compounds |
| EP1441750A4 (en) * | 2001-07-11 | 2006-10-18 | Palatin Technologies Inc | LINEAR AND CYCLIC PEPTIDES SPECIFIC TO THE MELANOCORTIN RECEPTOR |
| US7034004B2 (en) * | 2002-05-07 | 2006-04-25 | University Of Florida | Peptides and methods for the control of obesity |
| US20040128136A1 (en) * | 2002-09-20 | 2004-07-01 | Irani Pourang Polad | Internet voice browser |
| JP2006527773A (ja) * | 2003-06-19 | 2006-12-07 | イーライ リリー アンド カンパニー | メラノコルチン受容体4(mc4)作用薬とその用途 |
| US20060293223A1 (en) * | 2003-06-19 | 2006-12-28 | Eli Lilly And Company Patent Division | Uses of melanocortin-3 receptor (mc3r) agonist peptides |
| US7084111B2 (en) | 2003-06-23 | 2006-08-01 | University Of Florida Research Foundation, Inc. | Melanocortin receptor templates, peptides, and use thereof |
| ATE350369T1 (de) | 2003-08-20 | 2007-01-15 | Lilly Co Eli | Verbindungen, verfahren und formulierungen zur oralen verabreichung einer glucagon like peptide (glp)-1-verbindung oder eines am melanocortin-4- rezeptor (mc4) als agonist wirkenden peptids |
| US20070293423A1 (en) | 2003-08-20 | 2007-12-20 | Eli Lilly And Company | Compounds, Methods and Formulations for the Oral Delivery of a Glucagon-Like Peptide (Glp)-1 Compound or a Melanocortin-4 Receptor (Mc4) Agonist Peptide |
| US20050192286A1 (en) * | 2003-10-22 | 2005-09-01 | Neurocrine Biosciences, Inc. | Ligands of melanocortin receptors and compositions and methods related thereto |
| DE10355559A1 (de) | 2003-11-21 | 2005-06-23 | Orthogen Ag | Transskin |
| EP1694348A4 (en) | 2003-12-10 | 2009-07-01 | Merck & Co Inc | INHIBITION OF VOLUNTARY ETHANOL CONSUMPTION WITH SELECTIVE MELANOCORTIN-4-RECEPTOR AGONISTS |
| JP2007530674A (ja) | 2004-03-29 | 2007-11-01 | イーライ リリー アンド カンパニー | 連続注入によって投与されるメラノコルチン−4受容体(mc4r)アゴニストペプチドの使用 |
| WO2006037188A1 (en) | 2004-10-08 | 2006-04-13 | Clinuvel Pharmaceuticals Limited | Compositions and methods for inducing melanogenesis in a subject |
| WO2006073771A2 (en) | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Polyethylene glycol linked mc4r or mc3r agonist peptides |
| WO2006073772A1 (en) | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Polyethylene glycol linked mc4r or mc3r agonist peptides |
| EP2548568B1 (en) * | 2005-07-08 | 2018-01-10 | Ipsen Pharma | Melanocortin receptor ligands |
| US8466104B2 (en) | 2005-08-26 | 2013-06-18 | Abbvie Inc. | Therapeutically active alpha MSH analogues |
-
2006
- 2006-07-10 EP EP12188784.8A patent/EP2548568B1/en active Active
- 2006-07-10 EP EP10182566.9A patent/EP2286825B1/en active Active
- 2006-07-10 DK DK10170694.3T patent/DK2236151T3/da active
- 2006-07-10 HU HUE17202836A patent/HUE055154T2/hu unknown
- 2006-07-10 CN CN2006800324235A patent/CN101257916B/zh active Active
- 2006-07-10 DK DK17202836.7T patent/DK3354273T3/da active
- 2006-07-10 NZ NZ565217A patent/NZ565217A/en unknown
- 2006-07-10 EP EP21163411.8A patent/EP3925614A3/en active Pending
- 2006-07-10 RU RU2009131092/04A patent/RU2439079C2/ru active
- 2006-07-10 JP JP2008520417A patent/JP4734411B2/ja active Active
- 2006-07-10 PL PL12188784T patent/PL2548568T3/pl unknown
- 2006-07-10 US US11/988,533 patent/US8039435B2/en active Active
- 2006-07-10 CN CN201310495024.4A patent/CN103755786B/zh active Active
- 2006-07-10 PL PL10182566T patent/PL2286825T3/pl unknown
- 2006-07-10 CN CN200910174061A patent/CN101676298A/zh active Pending
- 2006-07-10 HU HUE12188784A patent/HUE037147T2/hu unknown
- 2006-07-10 HU HUE10182566A patent/HUE031731T2/en unknown
- 2006-07-10 SG SG201004921-1A patent/SG163585A1/en unknown
- 2006-07-10 PL PL17202836T patent/PL3354273T3/pl unknown
- 2006-07-10 AU AU2006269261A patent/AU2006269261B2/en active Active
- 2006-07-10 KR KR1020087002955A patent/KR100997177B1/ko active Active
- 2006-07-10 EP EP17202836.7A patent/EP3354273B1/en active Active
- 2006-07-10 EP EP06786665A patent/EP1915167A4/en not_active Withdrawn
- 2006-07-10 ES ES12188784.8T patent/ES2663916T3/es active Active
- 2006-07-10 DK DK10182566.9T patent/DK2286825T3/en active
- 2006-07-10 SI SI200632406T patent/SI3354273T1/sl unknown
- 2006-07-10 CA CA2793119A patent/CA2793119C/en active Active
- 2006-07-10 RU RU2008104803/04A patent/RU2380372C2/ru active
- 2006-07-10 CA CA2614615A patent/CA2614615C/en active Active
- 2006-07-10 PT PT172028367T patent/PT3354273T/pt unknown
- 2006-07-10 CA CA3044795A patent/CA3044795A1/en not_active Abandoned
- 2006-07-10 DK DK12188784.8T patent/DK2548568T3/en active
- 2006-07-10 PT PT121887848T patent/PT2548568T/pt unknown
- 2006-07-10 ES ES10182566.9T patent/ES2604328T3/es active Active
- 2006-07-10 PL PL10170694T patent/PL2236151T3/pl unknown
- 2006-07-10 CN CN201610168908.2A patent/CN105837661B/zh active Active
- 2006-07-10 CA CA3228910A patent/CA3228910A1/en active Pending
- 2006-07-10 ES ES17202836T patent/ES2877349T3/es active Active
- 2006-07-10 ES ES10170694T patent/ES2386862T3/es active Active
- 2006-07-10 EP EP10170694A patent/EP2236151B1/en active Active
- 2006-07-10 KR KR1020097022845A patent/KR101232201B1/ko active Active
- 2006-07-10 PT PT101825669T patent/PT2286825T/pt unknown
- 2006-07-10 WO PCT/US2006/026586 patent/WO2007008704A2/en not_active Ceased
- 2006-07-10 PT PT10170694T patent/PT2236151E/pt unknown
- 2006-07-10 NZ NZ580806A patent/NZ580806A/en not_active Application Discontinuation
- 2006-07-10 CN CN202411273113.9A patent/CN119119190A/zh active Pending
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2008
- 2008-01-02 IL IL188545A patent/IL188545A/en active IP Right Grant
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2009
- 2009-10-25 IL IL201732A patent/IL201732A/en active IP Right Grant
- 2009-10-28 AU AU2009230799A patent/AU2009230799B2/en active Active
- 2009-11-19 JP JP2009263603A patent/JP5889513B2/ja active Active
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2011
- 2011-03-29 US US13/074,565 patent/US9458195B2/en active Active
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2013
- 2013-08-08 JP JP2013165312A patent/JP2013253090A/ja active Pending
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2015
- 2015-07-14 JP JP2015140154A patent/JP5965520B2/ja active Active
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2016
- 2016-06-22 IL IL246392A patent/IL246392A/en active IP Right Grant
- 2016-09-07 US US15/257,970 patent/US20160368962A1/en not_active Abandoned
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2017
- 2017-05-05 US US15/587,426 patent/US9850280B2/en active Active
- 2017-12-04 US US15/830,038 patent/US20180105557A1/en not_active Abandoned
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2018
- 2018-07-09 US US16/029,837 patent/US20180305406A1/en not_active Abandoned
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2019
- 2019-12-04 US US16/702,661 patent/US20200095281A1/en not_active Abandoned
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2021
- 2021-12-06 NL NL301150C patent/NL301150I2/nl unknown
- 2021-12-14 FR FR21C1060C patent/FR21C1060I2/fr active Active
- 2021-12-15 HU HUS2100054C patent/HUS2100054I1/hu unknown
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2022
- 2022-01-10 US US17/572,115 patent/US20220127305A1/en not_active Abandoned
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