JP2008542403A5 - - Google Patents
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- Publication number
- JP2008542403A5 JP2008542403A5 JP2008515000A JP2008515000A JP2008542403A5 JP 2008542403 A5 JP2008542403 A5 JP 2008542403A5 JP 2008515000 A JP2008515000 A JP 2008515000A JP 2008515000 A JP2008515000 A JP 2008515000A JP 2008542403 A5 JP2008542403 A5 JP 2008542403A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- tooth surface
- subsurface
- amorphous calcium
- acfp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 21
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 108010001441 Phosphopeptides Proteins 0.000 claims 3
- 239000007844 bleaching agent Substances 0.000 claims 3
- 235000018102 proteins Nutrition 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 210000003298 Dental Enamel Anatomy 0.000 claims 2
- 102000035443 Peptidases Human genes 0.000 claims 2
- 108091005771 Peptidases Proteins 0.000 claims 2
- 239000004365 Protease Substances 0.000 claims 2
- QORWJWZARLRLPR-UHFFFAOYSA-H Tricalcium phosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 2
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 2
- 239000001506 calcium phosphate Substances 0.000 claims 2
- 235000011010 calcium phosphates Nutrition 0.000 claims 2
- GFIKIVSYJDVOOZ-UHFFFAOYSA-L calcium;fluoro-dioxido-oxo-$l^{5}-phosphane Chemical compound [Ca+2].[O-]P([O-])(F)=O GFIKIVSYJDVOOZ-UHFFFAOYSA-L 0.000 claims 2
- 230000003902 lesions Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- AQLJVWUFPCUVLO-UHFFFAOYSA-N Hydrogen peroxide - urea Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 claims 1
- SUKJFIGYRHOWBL-UHFFFAOYSA-N Sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims 1
- 239000005708 Sodium hypochlorite Substances 0.000 claims 1
- 229940078916 carbamide peroxide Drugs 0.000 claims 1
- 239000005018 casein Substances 0.000 claims 1
- 235000021240 caseins Nutrition 0.000 claims 1
- 230000003196 chaotropic Effects 0.000 claims 1
- 230000003628 erosive Effects 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
Claims (9)
- 歯表面または表面下を石灰化するための組成物であって、該組成物は、タンパク質破壊剤を含む第1組成物及び安定化アモルファスリン酸カルシウム(ACP)または安定化アモルファスフッ化リン酸カルシウム(ACFP)を含む第2組成物を含み、該第1組成物が該第2組成物の前に該歯表面または表面下に塗布されることにより特徴付けられる、組成物。
- 該歯表面が歯エナメル質である、請求項1に記載の組成物。
- 該歯表面が歯エナメル質における病変である、請求項1に記載の組成物。
- 該病変が虫歯、歯の浸食またはフッ素沈着により生じる、請求項3に記載の組成物。
- 該ACP及び/またはACFPが、ホスホペプチドで安定化されている、請求項1に記載の組成物。
- 該ホスホペプチドがカゼインホスホペプチドである、請求項5に記載の組成物。
- 該タンパク質破壊剤が、漂白剤、界面活性剤、カオトロピック剤、プロテアーゼ、及びプロテアーゼの混合物からなる群の1つ以上から選択される、請求項1に記載の組成物。
- 該漂白剤が次亜塩素酸ナトリウムまたは過酸化カルバミド漂白剤である、請求項7に記載の組成物。
- 第1組成物の製造におけるタンパク質破壊剤の使用、及び第2組成物の製造における安定化アモルファスリン酸カルシウム(ACP)または安定化アモルファスフッ化リン酸カルシウム(ACFP)の使用であって、該第1組成物及び該第2組成物は、歯表面または表面下を石灰化するために使用され、ここで、該第1組成物は、該第2組成物の前に該歯表面または表面下に塗布される、使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2005902961A AU2005902961A0 (en) | 2005-06-07 | Dental mineralisation | |
AU2005902961 | 2005-06-07 | ||
PCT/AU2006/000785 WO2006130913A1 (en) | 2005-06-07 | 2006-06-07 | Dental mineralization |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2008542403A JP2008542403A (ja) | 2008-11-27 |
JP2008542403A5 true JP2008542403A5 (ja) | 2009-07-23 |
JP5539648B2 JP5539648B2 (ja) | 2014-07-02 |
Family
ID=37498029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008515000A Active JP5539648B2 (ja) | 2005-06-07 | 2006-06-07 | 歯の石灰化 |
Country Status (15)
Country | Link |
---|---|
US (2) | US8673363B2 (ja) |
EP (1) | EP1888014B1 (ja) |
JP (1) | JP5539648B2 (ja) |
CN (2) | CN104013963A (ja) |
AR (1) | AR057353A1 (ja) |
AU (1) | AU2006255486B2 (ja) |
BR (1) | BRPI0610885B1 (ja) |
CA (1) | CA2611077C (ja) |
DK (1) | DK1888014T3 (ja) |
ES (1) | ES2399345T3 (ja) |
MX (1) | MX2007015496A (ja) |
NZ (1) | NZ563944A (ja) |
PT (1) | PT1888014E (ja) |
RU (1) | RU2413498C2 (ja) |
WO (1) | WO2006130913A1 (ja) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101098675B (zh) | 2004-11-25 | 2013-04-10 | 墨尔本大学 | 稳定的磷酸钙复合物 |
DK1888014T3 (da) | 2005-06-07 | 2013-02-18 | Univ Melbourne | Tandmineralisering |
AU2006261597B2 (en) | 2005-06-24 | 2011-06-23 | The University Of Melbourne | Ionic complexes |
WO2007090242A1 (en) * | 2006-02-09 | 2007-08-16 | The University Of Melbourne | Fluoride composition and methods for dental mineralization |
JP2009532065A (ja) * | 2006-04-05 | 2009-09-10 | キャドバリー アダムス ユーエスエー エルエルシー | 酸含有チューインガム中のリン酸カルシウム錯体 |
EA012038B1 (ru) * | 2007-05-11 | 2009-06-30 | Людмила Николаевна Дедова | Способ минерализации тканей корня зуба |
GB0807224D0 (en) | 2008-04-21 | 2008-05-28 | Univ Dundee | Remineralisation of calcified tissue |
BRPI0917321A2 (pt) | 2008-08-29 | 2015-11-17 | Oral Health Australia Pty Ltd | prevenção, tratamento e diagnóstico de infecção por p. gingivalis |
IT1392394B1 (it) * | 2008-12-22 | 2012-03-02 | Vittoria | Materiale composito dotato di proprietà di autoriparazione e di rilascio di principi attivi, per applicazioni biomediche |
US8741268B2 (en) * | 2009-09-10 | 2014-06-03 | Preventive Technologies, Inc. | Dental prophylactic paste |
JP5653638B2 (ja) * | 2010-03-02 | 2015-01-14 | 学校法人昭和大学 | エナメル質石灰化促進材セット |
US8715625B1 (en) | 2010-05-10 | 2014-05-06 | The Clorox Company | Natural oral care compositions |
KR102221531B1 (ko) | 2013-07-23 | 2021-03-02 | 더 유니버시티 오브 멜버른 | 치아 광화를 위한 조성물 및 방법 |
RU2541054C1 (ru) * | 2013-09-03 | 2015-02-10 | Евгений Андреевич Лавренюк | Способ лечения эрозии зубов |
WO2015095932A1 (en) | 2013-12-24 | 2015-07-02 | The University Of Melbourne | Stabilized stannous compositions |
JP2016102069A (ja) * | 2014-11-27 | 2016-06-02 | 株式会社ジーシー | 歯面清掃方法、歯面清掃用組成物、及びその使用方法 |
GB2535989A (en) * | 2015-02-26 | 2016-09-07 | Dr Heff's Products Ltd | Dental product, use of a dental product and methods of use of a dental product |
WO2017072104A1 (en) | 2015-10-26 | 2017-05-04 | Basf Se | Oral care products and methods comprising antifreeze proteins |
EA201991933A1 (ru) | 2017-03-14 | 2020-03-05 | Де Юниверсити Оф Мельбурн | Лечение гингивита |
EP3897524A4 (en) * | 2018-12-18 | 2023-04-26 | International Flavors & Fragrances Inc. | PROTEIN MICROCAPSULES AND THEIR PREPARATION METHOD |
BR112021018034A2 (pt) * | 2019-03-13 | 2021-11-23 | Univ Melbourne | Encobrimento de lesões hipomineralizadas |
EP3937882A4 (en) * | 2019-03-13 | 2023-04-12 | The University of Melbourne | COMPOSITIONS AND METHODS FOR PROMOTING MINERALIZATION |
CN111249178A (zh) * | 2020-03-20 | 2020-06-09 | 成都爱睿康乐医疗器械有限公司 | 一种儿童防龋牙膏 |
EP4252861A1 (en) * | 2020-11-24 | 2023-10-04 | Nishio Co., Ltd. | Tooth strengthening method and tooth whitening method |
WO2024042191A1 (en) | 2022-08-26 | 2024-02-29 | Blissandmore Gmbh | Oral care compositions |
WO2024089262A1 (en) | 2022-10-28 | 2024-05-02 | Queen Mary University Of London | Toothpaste composition |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4522805A (en) | 1983-06-08 | 1985-06-11 | Norman Gordon | Tooth and gum dentifrice |
CA1315480C (en) | 1986-06-12 | 1993-03-30 | Eric Charles Reynolds | Phosphopeptides |
US5015628A (en) | 1986-06-12 | 1991-05-14 | The University Of Melbourne | Anticariogenic phosphopeptides |
US6056930A (en) | 1989-05-24 | 2000-05-02 | American Dental Association Health Foundation | Methods and compositions for mineralizing and fluoridating calcified tissues |
US5227154A (en) | 1991-08-22 | 1993-07-13 | The University Of Melbourne | Phosphopeptides for the treatment of dental calculus |
KR100238551B1 (ko) | 1992-06-29 | 2000-02-01 | 도우글라스 웨이르 | 민감성 치아 치료 |
JP3340265B2 (ja) * | 1994-11-21 | 2002-11-05 | 一枝 山岸 | 歯の漂白剤 |
JP4040705B2 (ja) | 1996-01-24 | 2008-01-30 | 株式会社サンギ | 口腔組成物 |
JP2975337B2 (ja) | 1997-02-20 | 1999-11-10 | 雪印乳業株式会社 | カルシウム複合体 |
AUPO566297A0 (en) * | 1997-03-13 | 1997-04-10 | University Of Melbourne, The | Calcium phosphopeptide complexes |
FR2791573B1 (fr) | 1999-03-30 | 2003-04-11 | Pf Medicament | Utilisation d'un extrait de serenoa repens pour la fabrication d'un medicament destine au traitement du cancer de la prostate |
US6521215B2 (en) | 1999-05-28 | 2003-02-18 | Devin Okay | Compositions and methods for tooth treatment |
US6685920B2 (en) | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
GB9929919D0 (en) | 1999-12-17 | 2000-02-09 | Hannah Research Inst The | Calcium phosphate nanoclusters and their applications |
JP2002338447A (ja) * | 2001-05-15 | 2002-11-27 | Kuraray Co Ltd | 歯科用組成物 |
AUPR517701A0 (en) | 2001-05-21 | 2001-06-14 | University Of Melbourne, The | Dental restorative materials |
MXPA04006541A (es) | 2002-01-03 | 2004-10-04 | Procter & Gamble | Composiciones bucales estables que contienen complejos de fosfopeptido de caseina y fluoruro. |
MXPA04006542A (es) | 2002-01-03 | 2004-10-04 | Procter & Gamble | Composiciones bucales estables que contienen complejos de fosfopeptido de caseina y fluooruro. |
NZ522071A (en) | 2002-10-18 | 2005-07-29 | Patrick Joseph Silcock | Hydrolysed casein phosphoprotein preparations for bioactive metal ion delivery and teeth remineralisation |
JP4340069B2 (ja) | 2003-01-10 | 2009-10-07 | 雪印乳業株式会社 | カルシウム複合体の製造法 |
US20050089481A1 (en) | 2003-10-23 | 2005-04-28 | Gc Corporation | Composition for caries prevention |
US20060183081A1 (en) * | 2004-09-27 | 2006-08-17 | Al Bevilacqua | Tooth bleaching system and method |
DK1888014T3 (da) | 2005-06-07 | 2013-02-18 | Univ Melbourne | Tandmineralisering |
-
2006
- 2006-06-07 DK DK06741201.5T patent/DK1888014T3/da active
- 2006-06-07 US US11/916,831 patent/US8673363B2/en active Active
- 2006-06-07 BR BRPI0610885-7A patent/BRPI0610885B1/pt active IP Right Grant
- 2006-06-07 RU RU2007149555/15A patent/RU2413498C2/ru active
- 2006-06-07 PT PT67412015T patent/PT1888014E/pt unknown
- 2006-06-07 EP EP06741201A patent/EP1888014B1/en active Active
- 2006-06-07 WO PCT/AU2006/000785 patent/WO2006130913A1/en active Application Filing
- 2006-06-07 NZ NZ563944A patent/NZ563944A/en unknown
- 2006-06-07 CN CN201410200554.6A patent/CN104013963A/zh active Pending
- 2006-06-07 MX MX2007015496A patent/MX2007015496A/es active IP Right Grant
- 2006-06-07 AU AU2006255486A patent/AU2006255486B2/en active Active
- 2006-06-07 CA CA2611077A patent/CA2611077C/en active Active
- 2006-06-07 CN CNA2006800249338A patent/CN101217932A/zh active Pending
- 2006-06-07 JP JP2008515000A patent/JP5539648B2/ja active Active
- 2006-06-07 ES ES06741201T patent/ES2399345T3/es active Active
- 2006-06-07 AR ARP060102378A patent/AR057353A1/es unknown
-
2014
- 2014-01-29 US US14/167,493 patent/US20140147512A1/en not_active Abandoned
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