JP2008535821A5 - - Google Patents
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- Publication number
- JP2008535821A5 JP2008535821A5 JP2008503236A JP2008503236A JP2008535821A5 JP 2008535821 A5 JP2008535821 A5 JP 2008535821A5 JP 2008503236 A JP2008503236 A JP 2008503236A JP 2008503236 A JP2008503236 A JP 2008503236A JP 2008535821 A5 JP2008535821 A5 JP 2008535821A5
- Authority
- JP
- Japan
- Prior art keywords
- antagonist
- met
- exon
- stabilized
- over
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66548205P | 2005-03-25 | 2005-03-25 | |
| PCT/US2006/010850 WO2006104911A2 (en) | 2005-03-25 | 2006-03-24 | Methods and compositions for modulating hyperstabilized c-met |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012116934A Division JP2012232979A (ja) | 2005-03-25 | 2012-05-22 | 過剰に安定化したｃ−ｍｅｔを調節するための方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008535821A JP2008535821A (ja) | 2008-09-04 |
| JP2008535821A5 true JP2008535821A5 (https=) | 2009-04-09 |
Family
ID=37053941
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503236A Pending JP2008535821A (ja) | 2005-03-25 | 2006-03-24 | 過剰に安定化したｃ−ｍｅｔを調節するための方法及び組成物 |
| JP2012116934A Pending JP2012232979A (ja) | 2005-03-25 | 2012-05-22 | 過剰に安定化したｃ−ｍｅｔを調節するための方法及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012116934A Pending JP2012232979A (ja) | 2005-03-25 | 2012-05-22 | 過剰に安定化したｃ−ｍｅｔを調節するための方法及び組成物 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7615529B2 (https=) |
| EP (1) | EP1868648B1 (https=) |
| JP (2) | JP2008535821A (https=) |
| KR (1) | KR20080000613A (https=) |
| CN (1) | CN101184506B (https=) |
| AU (1) | AU2006229989B2 (https=) |
| BR (1) | BRPI0611468A2 (https=) |
| CA (1) | CA2599988A1 (https=) |
| ES (1) | ES2539790T3 (https=) |
| IL (1) | IL185708A (https=) |
| MX (1) | MX2007011652A (https=) |
| NO (1) | NO20075412L (https=) |
| NZ (1) | NZ561211A (https=) |
| RU (1) | RU2404193C2 (https=) |
| SG (1) | SG159547A1 (https=) |
| WO (1) | WO2006104911A2 (https=) |
| ZA (1) | ZA200707953B (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006104911A2 (en) * | 2005-03-25 | 2006-10-05 | Genentech, Inc. | Methods and compositions for modulating hyperstabilized c-met |
| RU2601892C2 (ru) * | 2008-03-06 | 2016-11-10 | Дженентек, Инк. | Комбинированная терапия антагонистами с-мет и egfr |
| NZ591087A (en) * | 2008-10-01 | 2012-08-31 | Micromet Ag | Cross-species-specific pscaxcd3, cd19xcd3, c-metxcd3, endosialinxcd3, epcamxc d3, igf-1rxcd3 or fapalpha xcd3 bispecific single chain antibody |
| PA8849001A1 (es) | 2008-11-21 | 2010-06-28 | Lilly Co Eli | Anticuerpos de c-met |
| BRPI1014449A2 (pt) | 2009-04-07 | 2017-06-27 | Roche Glycart Ag | anticorpos biespecíficos anti-erbb-2/ anti-c-met. |
| MX2011010166A (es) | 2009-04-07 | 2011-10-11 | Roche Glycart Ag | Anticuerpos biespecificos anti-erbb-3/anti-c-met. |
| DK2421898T3 (en) | 2009-04-20 | 2016-05-30 | Oxford Biotherapeutics Ltd | Cadherin-17 SPECIFIC ANTIBODIES |
| KR101671378B1 (ko) * | 2009-10-30 | 2016-11-01 | 삼성전자 주식회사 | ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그의 용도 |
| BR112012010153B1 (pt) | 2009-11-05 | 2022-05-03 | Genentech, Inc | Método de produção de um anticorpo |
| EP3511342B1 (en) | 2010-03-10 | 2024-01-17 | Genmab A/S | Monoclonal antibodies against c-met |
| NZ610091A (en) * | 2010-10-20 | 2015-02-27 | Oxford Biotherapeutics Ltd | Antibodies |
| RU2013155695A (ru) | 2011-06-30 | 2015-08-10 | Дженентек, Инк. | Препараты антител против с-мет |
| EP2748197A2 (en) | 2011-08-26 | 2014-07-02 | Merrimack Pharmaceuticals, Inc. | Tandem fc bispecific antibodies |
| CA2843771A1 (en) | 2011-09-20 | 2013-03-28 | Eli Lilly And Company | Anti-c-met antibodies |
| WO2013049112A1 (en) * | 2011-09-27 | 2013-04-04 | Emory University | Detection of biomarkers using magnetic resonance |
| KR20130036993A (ko) | 2011-10-05 | 2013-04-15 | 삼성전자주식회사 | ｃ-Ｍｅｔ의 ＳＥＭＡ 도메인 내의 에피토프에 특이적으로 결합하는 항체 |
| EP2782932A1 (en) * | 2011-11-21 | 2014-10-01 | F.Hoffmann-La Roche Ag | Purification of anti-c-met antibodies |
| EP2708556B1 (en) | 2012-09-12 | 2018-11-07 | Samsung Electronics Co., Ltd | Pharmaceutical composition for the use in a combination therapy for prevention or treatment of c-met or angiogenesis factor induced diseases |
| CN104837502B (zh) | 2012-10-12 | 2018-08-10 | 麦迪穆有限责任公司 | 吡咯并苯并二氮杂卓及其结合物 |
| US10260089B2 (en) | 2012-10-29 | 2019-04-16 | The Research Foundation Of The State University Of New York | Compositions and methods for recognition of RNA using triple helical peptide nucleic acids |
| US20150259430A1 (en) | 2012-11-05 | 2015-09-17 | Mab Discovery Gmbh | Method for the production of multispecific antibodies |
| EP2727941A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Method for the production of multispecific antibodies |
| TW201444872A (zh) | 2013-03-06 | 2014-12-01 | Merrimack Pharmaceuticals Inc | 抗Ｃ－ＭＥＴ串聯Ｆｃ雙特異性抗體 |
| CA2905181C (en) | 2013-03-13 | 2020-06-02 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof for providing targeted therapy |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| US9567641B2 (en) * | 2013-07-03 | 2017-02-14 | Samsung Electronics Co., Ltd. | Combination therapy for the treatment of cancer using an anti-C-met antibody |
| BR112016010927A2 (pt) | 2013-11-14 | 2017-08-08 | Endocyte Inc | Conjugado de fórmula |
| EP3116999B1 (en) | 2014-03-14 | 2021-09-15 | F. Hoffmann-La Roche AG | Methods and compositions for secretion of heterologous polypeptides |
| EP3122900A1 (en) | 2014-03-24 | 2017-02-01 | F. Hoffmann-La Roche AG | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression |
| JP6531166B2 (ja) | 2014-09-10 | 2019-06-12 | メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ | ピロロベンゾジアゼピン及びそのコンジュゲート |
| US10450376B2 (en) | 2014-09-16 | 2019-10-22 | Symphogen A/S | Anti-MET antibodies and compositions |
| GB201419108D0 (en) * | 2014-10-27 | 2014-12-10 | Glythera Ltd | Materials and methods relating to linkers for use in antibody drug conjugates |
| CN107613974B (zh) | 2015-03-16 | 2021-01-15 | 塞尔德克斯医疗公司 | 抗-met抗体及其使用方法 |
| KR102561356B1 (ko) | 2016-09-14 | 2023-08-03 | 애브비 바이오테라퓨틱스 인크. | 항-pd-1 항체 및 이의 용도 |
| CN109862919A (zh) | 2016-10-11 | 2019-06-07 | 免疫医疗有限公司 | 抗体-药物缀合物联合免疫介导的治疗剂 |
| TWI782930B (zh) | 2016-11-16 | 2022-11-11 | 美商再生元醫藥公司 | 抗ｍｅｔ抗體，結合ｍｅｔ之雙特異性抗原結合分子及其使用方法 |
| US12208102B2 (en) | 2018-04-17 | 2025-01-28 | Endocyte, Inc. | Methods of treating cancer |
| CA3098103A1 (en) | 2018-05-23 | 2019-11-28 | Adc Therapeutics Sa | Molecular adjuvant |
| EA202190267A1 (ru) | 2018-07-15 | 2021-05-17 | Инокиан Байофарма, Инк. | Способы и композиции с использованием рекомбинантных дендритных клеток для терапии рака |
| SG11202108311RA (en) | 2019-02-26 | 2021-09-29 | Janssen Biotech Inc | Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies |
| WO2020230091A1 (en) | 2019-05-14 | 2020-11-19 | Janssen Biotech, Inc. | Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors |
| US11850248B2 (en) | 2019-05-14 | 2023-12-26 | Yuhan Corporation | Therapies with 3rd generation EGFR tyrosine kinase inhibitors |
| CN114096264B (zh) | 2019-05-20 | 2025-03-14 | 因多塞特股份有限公司 | 制备psma缀合物的方法 |
| US11896682B2 (en) | 2019-09-16 | 2024-02-13 | Regeneron Pharmaceuticals, Inc. | Radiolabeled MET binding proteins for immuno-PET imaging and methods of use thereof |
| PH12022552076A1 (en) | 2020-02-12 | 2023-11-29 | Janssen Biotech Inc | TREATMENT OF PATIENTS HAVING c-MET EXON 14 SKIPPING MUTATIONS |
| US20230372528A1 (en) | 2020-10-16 | 2023-11-23 | University Of Georgia Research Foundation, Inc. | Glycoconjugates |
| CN114478788B (zh) | 2020-11-11 | 2025-07-18 | 北京免疫方舟医药科技有限公司 | 一种同时靶向cd3和cd137的融合蛋白及其制备方法和用途 |
| GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
| CN117980327A (zh) | 2021-11-03 | 2024-05-03 | 杭州多禧生物科技有限公司 | 抗体的特异性偶联 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5686292A (en) * | 1995-06-02 | 1997-11-11 | Genentech, Inc. | Hepatocyte growth factor receptor antagonist antibodies and uses thereof |
| JP2000510330A (ja) | 1996-04-05 | 2000-08-15 | トーマス・ジェファーソン・ユニバーシティ | 癌の診断および予後のための方法 |
| IL127558A0 (en) * | 1996-07-03 | 1999-10-28 | Genentech Inc | Hepatocyte growth factor receptor agonists and uses thereof |
| DE19651443A1 (de) * | 1996-12-11 | 1998-06-18 | Hoechst Ag | Selbstverstärkende, pharmakologisch kontrollierbare Expressionssysteme |
| WO2003088808A2 (en) * | 2002-04-16 | 2003-10-30 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| WO2004072117A2 (en) * | 2003-02-13 | 2004-08-26 | Pharmacia Corporation | Antibodies to c-met for the treatment of cancers |
| MXPA05013181A (es) * | 2003-06-06 | 2006-06-23 | Genentech Inc | Metodos y composiciones para modular hgf/met. |
| HN2004000285A (es) * | 2003-08-04 | 2006-04-27 | Pfizer Prod Inc | ANTICUERPOS DIRIGIDOS A c-MET |
| US20050233960A1 (en) * | 2003-12-11 | 2005-10-20 | Genentech, Inc. | Methods and compositions for inhibiting c-met dimerization and activation |
| KR100956913B1 (ko) * | 2003-12-19 | 2010-05-11 | 제넨테크, 인크. | 치료제로서 유용한 일가 항체 단편 |
| AU2006229990A1 (en) | 2005-03-25 | 2006-10-05 | Genentech, Inc. | C-met mutations in lung cancer |
| WO2006104911A2 (en) | 2005-03-25 | 2006-10-05 | Genentech, Inc. | Methods and compositions for modulating hyperstabilized c-met |
-
2006
- 2006-03-24 WO PCT/US2006/010850 patent/WO2006104911A2/en not_active Ceased
- 2006-03-24 KR KR1020077024503A patent/KR20080000613A/ko not_active Ceased
- 2006-03-24 RU RU2007139452/10A patent/RU2404193C2/ru active
- 2006-03-24 AU AU2006229989A patent/AU2006229989B2/en not_active Expired
- 2006-03-24 CA CA002599988A patent/CA2599988A1/en not_active Abandoned
- 2006-03-24 BR BRPI0611468-7A patent/BRPI0611468A2/pt not_active Application Discontinuation
- 2006-03-24 ZA ZA200707953A patent/ZA200707953B/xx unknown
- 2006-03-24 NZ NZ561211A patent/NZ561211A/en not_active IP Right Cessation
- 2006-03-24 EP EP06748671.2A patent/EP1868648B1/en not_active Expired - Lifetime
- 2006-03-24 CN CN2006800183951A patent/CN101184506B/zh not_active Expired - Lifetime
- 2006-03-24 US US11/388,757 patent/US7615529B2/en active Active
- 2006-03-24 JP JP2008503236A patent/JP2008535821A/ja active Pending
- 2006-03-24 MX MX2007011652A patent/MX2007011652A/es active IP Right Grant
- 2006-03-24 ES ES06748671.2T patent/ES2539790T3/es not_active Expired - Lifetime
- 2006-03-24 SG SG201000940-5A patent/SG159547A1/en unknown
-
2007
- 2007-09-04 IL IL185708A patent/IL185708A/en active IP Right Grant
- 2007-10-24 NO NO20075412A patent/NO20075412L/no not_active Application Discontinuation
-
2009
- 2009-09-29 US US12/569,552 patent/US8536118B2/en active Active
-
2012
- 2012-05-22 JP JP2012116934A patent/JP2012232979A/ja active Pending
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