JP2004532839A5 - - Google Patents

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Publication number
JP2004532839A5
JP2004532839A5 JP2002577925A JP2002577925A JP2004532839A5 JP 2004532839 A5 JP2004532839 A5 JP 2004532839A5 JP 2002577925 A JP2002577925 A JP 2002577925A JP 2002577925 A JP2002577925 A JP 2002577925A JP 2004532839 A5 JP2004532839 A5 JP 2004532839A5
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JP
Japan
Prior art keywords
mif
polypeptide
mammal
fragment
antagonist
Prior art date
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Application number
JP2002577925A
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English (en)
Japanese (ja)
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JP2004532839A (ja
JP4202763B2 (ja
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Priority claimed from PCT/US2002/009580 external-priority patent/WO2002079517A1/en
Publication of JP2004532839A publication Critical patent/JP2004532839A/ja
Publication of JP2004532839A5 publication Critical patent/JP2004532839A5/ja
Application granted granted Critical
Publication of JP4202763B2 publication Critical patent/JP4202763B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002577925A 2001-03-29 2002-03-29 マクロファージ遊走阻止因子レセプターとしてのｍｈｃクラスｉｉ不変鎖ポリペプチド使用のための方法及び組成物 Expired - Fee Related JP4202763B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27943501P 2001-03-29 2001-03-29
PCT/US2002/009580 WO2002079517A1 (en) 2001-03-29 2002-03-29 Methods and compositions for using mhc class ii invariant chain polypeptide as a receptor for macrophage migration inhibitory factor

Publications (3)

Publication Number Publication Date
JP2004532839A JP2004532839A (ja) 2004-10-28
JP2004532839A5 true JP2004532839A5 (https=) 2005-12-22
JP4202763B2 JP4202763B2 (ja) 2008-12-24

Family

ID=23068959

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002577925A Expired - Fee Related JP4202763B2 (ja) 2001-03-29 2002-03-29 マクロファージ遊走阻止因子レセプターとしてのｍｈｃクラスｉｉ不変鎖ポリペプチド使用のための方法及び組成物

Country Status (10)

Country Link
US (10) US20030013122A1 (https=)
EP (1) EP1383919B1 (https=)
JP (1) JP4202763B2 (https=)
AT (1) ATE473294T1 (https=)
AU (1) AU2002255961B2 (https=)
CA (1) CA2455915C (https=)
DE (1) DE60236921D1 (https=)
DK (1) DK1383919T3 (https=)
ES (1) ES2352228T3 (https=)
WO (1) WO2002079517A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7312318B2 (en) * 2002-03-01 2007-12-25 Immunomedics, Inc. Internalizing anti-CD74 antibodies and methods of use
DK1383919T3 (da) * 2001-03-29 2010-11-08 Cytokine Pharmasciences Inc Fremgangsmåder og sammensætninger til anvendelse af MHC klasse II-invariant kædepolypeptid som en receptor for makrofag migrationsinhiberede faktor
UY27304A1 (es) 2001-05-24 2002-12-31 Avanir Pharmaceuticals Inhibidores del factor inhibidor de la migración de los macrófagos y métodos para su identificación
US20160279239A1 (en) 2011-05-02 2016-09-29 Immunomedics, Inc. Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
EP1500402A4 (en) 2002-04-26 2009-12-30 Takeda Pharmaceutical INHIBITOR OF CELL DEATH
US20050208010A1 (en) * 2002-07-10 2005-09-22 L'oreal Genes from Chromosome 3, 5 and 11 involved in premature canities
TW200418829A (en) 2003-02-14 2004-10-01 Avanir Pharmaceutics Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
US20050202010A1 (en) * 2003-08-29 2005-09-15 Giroir Brett P. Method of treatment and bioassay involving macrophage migration inhibitory factor (MIF) as cardiac-derived myocardial depressant factor
US20160355591A1 (en) 2011-05-02 2016-12-08 Immunomedics, Inc. Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
WO2006102191A1 (en) 2005-03-24 2006-09-28 Avanir Pharmaceuticals Thienopyridinone derivatives as macrophage migration inhibitory factor inhibitors
WO2007044622A1 (en) 2005-10-07 2007-04-19 Yale University Use of mif and mif pathway agonists
WO2013010955A1 (en) 2011-07-15 2013-01-24 Morphosys Ag Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt)
WO2013012894A1 (en) 2011-07-18 2013-01-24 The Ohio State University Fty720 increases cd74 expression and sensitizes cancer cells to anti-cd74 antibody-mediated cell death
US9958456B2 (en) 2011-10-07 2018-05-01 Baxalta Incorporated OxMIF as a diagnostic marker
CA2898472C (en) 2013-02-15 2023-03-07 Immunomedics, Inc. Chimeric and humanized anti-histone antibodies
EP3052526A4 (en) 2013-10-03 2017-04-19 Oregon Health & Science University Recombinant polypeptides comprising mhc class ii 1 domains
EP2944310B1 (en) 2014-05-16 2018-03-21 Mifcare MIF inhibitors for the acute or chronic treatment of pulmonary hypertension
EP3160504B1 (en) 2014-06-24 2020-09-16 Immunomedics, Inc. Anti-histone therapy for vascular necrosis in severe glomerulonephritis
US10351621B2 (en) 2014-06-24 2019-07-16 Immunomedics, Inc. Anti-histone therapy in acute kidney injury
US11397182B2 (en) 2014-10-07 2022-07-26 Cornell University Methods for prognosing and preventing metastatic liver disease
WO2017070569A1 (en) * 2015-10-23 2017-04-27 Oregon Health & Science University Compounds that bind macrophage migration inhibitory factor
US10799597B2 (en) 2017-04-03 2020-10-13 Immunomedics, Inc. Subcutaneous administration of antibody-drug conjugates for cancer therapy
CN114668832A (zh) * 2022-04-27 2022-06-28 西安市第一医院 Mif及其受体cd74制备调控细胞功能和分裂增殖药物中的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02124759A (ja) * 1988-07-15 1990-05-14 Sumitomo Electric Ind Ltd 超電導材料の製造方法
WO1990011301A1 (en) * 1989-03-17 1990-10-04 Genetics Institute, Inc. Human macrophage migration inhibitory factor
JP4708510B2 (ja) * 1993-05-17 2011-06-22 サイトカイン ファーマサイエンシズ，インコーポレーテッド サイトカイン媒介毒性に関係する疾患の治療における遊走阻止因子の抑制
US6645493B1 (en) * 1993-05-17 2003-11-11 The Picower Institute For Medical Research Composition containing anti-MIF antibody
US6774227B1 (en) * 1993-05-17 2004-08-10 Cytokine Pharmasciences, Inc. Therapeutic uses of factors which inhibit or neutralize MIF activity
US5559028A (en) * 1993-05-19 1996-09-24 Antigen Express, Inc. Methods of enhancing or antigen presentation to T cells inhibiting
US5586694A (en) 1994-12-14 1996-12-24 Fragrance Systems International, Inc. Perfume applicator with replaceable cartridges
WO1997025344A1 (en) * 1996-01-03 1997-07-17 The Australian National University Clip analogues and autoimmune disease
US6420188B1 (en) * 1996-02-16 2002-07-16 The Picower Institute For Medical Research Screening assay for the identification of inhibitors for macrophage migration inhibitory factor
US6492428B1 (en) * 2000-07-26 2002-12-10 The Picower Institute For Medical Research Compounds having MIF antagonist activity
US5726020A (en) * 1996-06-11 1998-03-10 University Of Massachusetts Inhibition of II synthesis
US6326465B1 (en) * 1997-02-24 2001-12-04 The Johns Hopkins University Immunomodulatory polypeptides derived from the invariant chain of MHC class II
JP3835827B2 (ja) * 1997-05-02 2006-10-18 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ，アズ リプレゼンティッド バイ ザ セクレタリーオブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 悪性細胞に対する、ｏｎｃタンパク質を含む、免疫毒素
CA2205680A1 (en) * 1997-05-16 1998-11-16 The University Of Western Ontario Clip immunomodulatory peptide
DE60042785D1 (de) * 1999-06-09 2009-10-01 Immunomedics Inc Immuntherapie von autoimmunerkrankungen durch die verwendung von b-zell spezifischen antikörpern
CA2389229A1 (en) * 1999-10-29 2001-05-10 The Picower Institute For Medical Research Compounds having mif antagonist activity
DK1383919T3 (da) * 2001-03-29 2010-11-08 Cytokine Pharmasciences Inc Fremgangsmåder og sammensætninger til anvendelse af MHC klasse II-invariant kædepolypeptid som en receptor for makrofag migrationsinhiberede faktor
UY27304A1 (es) * 2001-05-24 2002-12-31 Avanir Pharmaceuticals Inhibidores del factor inhibidor de la migración de los macrófagos y métodos para su identificación
US9540322B2 (en) * 2008-08-18 2017-01-10 Yale University MIF modulators
US9643922B2 (en) * 2008-08-18 2017-05-09 Yale University MIF modulators

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