JP2011507810A5 - - Google Patents
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- Publication number
- JP2011507810A5 JP2011507810A5 JP2010538206A JP2010538206A JP2011507810A5 JP 2011507810 A5 JP2011507810 A5 JP 2011507810A5 JP 2010538206 A JP2010538206 A JP 2010538206A JP 2010538206 A JP2010538206 A JP 2010538206A JP 2011507810 A5 JP2011507810 A5 JP 2011507810A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- fragment
- pag
- seq
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012634 fragment Substances 0.000 claims 14
- 229920001184 polypeptide Polymers 0.000 claims 14
- 108090000765 processed proteins & peptides Proteins 0.000 claims 14
- 102000004196 processed proteins & peptides Human genes 0.000 claims 14
- 230000035935 pregnancy Effects 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 7
- 102000036639 antigens Human genes 0.000 claims 7
- 108091007433 antigens Proteins 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
- 241000283690 Bos taurus Species 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 210000002826 placenta Anatomy 0.000 claims 2
- 238000001262 western blot Methods 0.000 claims 2
- 102000002260 Alkaline Phosphatase Human genes 0.000 claims 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 claims 1
- 238000002965 ELISA Methods 0.000 claims 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 claims 1
- 239000004793 Polystyrene Substances 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 210000004408 hybridoma Anatomy 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 238000001114 immunoprecipitation Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229920002223 polystyrene Polymers 0.000 claims 1
- 238000003118 sandwich ELISA Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1360307P | 2007-12-13 | 2007-12-13 | |
| US61/013,603 | 2007-12-13 | ||
| PCT/US2008/086674 WO2009076632A1 (en) | 2007-12-13 | 2008-12-12 | Compositions and methods for early pregnancy diagnosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011507810A JP2011507810A (ja) | 2011-03-10 |
| JP2011507810A5 true JP2011507810A5 (https=) | 2012-01-26 |
| JP5679818B2 JP5679818B2 (ja) | 2015-03-04 |
Family
ID=40427459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538206A Active JP5679818B2 (ja) | 2007-12-13 | 2008-12-12 | 早期妊娠診断のための組成物および方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8431349B2 (https=) |
| EP (1) | EP2225274B1 (https=) |
| JP (1) | JP5679818B2 (https=) |
| KR (1) | KR101637613B1 (https=) |
| CN (1) | CN101918445B (https=) |
| AU (1) | AU2008334976B2 (https=) |
| BR (1) | BRPI0820885B8 (https=) |
| CA (1) | CA2709305C (https=) |
| CO (1) | CO6280567A2 (https=) |
| DK (1) | DK2225274T3 (https=) |
| ES (1) | ES2623459T3 (https=) |
| HU (1) | HUE034401T2 (https=) |
| NZ (1) | NZ586100A (https=) |
| WO (1) | WO2009076632A1 (https=) |
| ZA (1) | ZA201004487B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8192946B2 (en) | 2008-04-10 | 2012-06-05 | The Curators Of The University Of Missouri | Assays for detecting pregnancy-associated glycoproteins |
| US8541187B2 (en) | 2011-03-01 | 2013-09-24 | Bio Tracking, LLC | Systems and methods for detecting animal pregnancy |
| US9241977B2 (en) * | 2013-03-01 | 2016-01-26 | Arthrex, Inc. | Enhanced anabolic cytokine production and delivery system |
| CN105424937B (zh) * | 2015-10-05 | 2017-11-21 | 华中农业大学 | 一种猴早期妊娠检测的孕酮胶体金免疫层析试纸条 |
| CN107219368B (zh) * | 2017-06-06 | 2019-02-26 | 山西农业大学 | 奶牛pag1检测试纸条及其制备方法 |
| CN107853241A (zh) * | 2017-10-16 | 2018-03-30 | 广西壮族自治区水牛研究所 | 一种提高水牛配种效率的方法 |
| KR102189893B1 (ko) * | 2017-11-15 | 2020-12-11 | (주)에스엘에스바이오 | bPAG1에 특이적으로 결합하는 항체 및 이의 용도 |
| CN108314732A (zh) * | 2018-01-15 | 2018-07-24 | 妊达（北京）生物技术有限公司 | 一种抗牛早孕因子单克隆抗体细胞株单克隆抗体的制备方法 |
| CN109295003B (zh) * | 2018-09-10 | 2022-03-04 | 吉林医药学院 | 产生牛妊娠相关糖蛋白特异性单克隆抗体的小鼠杂交瘤细胞株、单克隆抗体、试剂盒及检测 |
| CN111500583B (zh) * | 2020-03-04 | 2021-09-10 | 新疆农垦科学院 | 特异性识别牛妊娠相关糖蛋白4的核酸适配体及其应用 |
| MX2023007151A (es) * | 2020-12-20 | 2023-06-28 | Regeneron Pharma | Metodos para la identificacion de disulfuros aleatorizados en biomoleculas. |
| CN113960025A (zh) * | 2021-10-12 | 2022-01-21 | 北京农学院 | 一种奶牛早期妊娠的检测方法 |
| KR102917186B1 (ko) * | 2021-11-04 | 2026-01-28 | 주식회사 나노바이오라이프 | 소 임신 진단 항체와 이를 이용한 조기 임신 진단키트 개발 |
| CN114672464B (zh) * | 2022-03-31 | 2024-10-01 | 吴峰 | 一种分泌抗牛妊娠相关糖蛋白单克隆抗体的杂交瘤细胞、单克隆抗体及应用 |
| CN117820434B (zh) * | 2023-12-31 | 2024-11-19 | 武汉优恩生物科技有限公司 | 牛羊妊娠相关糖蛋白的多肽抗原及应用 |
| CN119285785B (zh) * | 2024-09-26 | 2025-04-18 | 武汉奥科博泰生物科技有限公司 | 一种抗d-二聚体单克隆抗体及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4208479A (en) * | 1977-07-14 | 1980-06-17 | Syva Company | Label modified immunoassays |
| US4271140A (en) * | 1978-01-23 | 1981-06-02 | Baxter Travenol Laboratories, Inc. | Method and composition for double receptor, specific binding assays |
| US4755460A (en) | 1984-07-06 | 1988-07-05 | The Regents Of The Univ. Of Minnesota | Bovine antigen glycoprotein, related antibody, and use in detection of pregnancy in cattle |
| US4895804A (en) * | 1984-07-06 | 1990-01-23 | University Of Minnesota | Bovine antigen glycoprotein, related antibody, and use in detection of pregnancy in cattle |
| EP0195406B1 (en) * | 1985-03-18 | 1991-10-23 | Mitsubishi Petrochemical Co., Ltd. | Process for producing highly water-absorbing polymer |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| DE19733505A1 (de) | 1997-08-01 | 1999-02-04 | Knoll Ag | Schnell wirksames Analgeticum |
| CA2319417A1 (en) * | 1998-02-02 | 1999-08-05 | Concepto Diagnostics, Inc. | Method and apparatus for detecting conception in animals |
| WO1999047934A2 (en) * | 1998-03-20 | 1999-09-23 | The Curators Of The University Of Missouri | Early pregnancy diagnosis using pags (pregnancy-associated glycoproteins) |
| NZ529254A (en) * | 2001-06-19 | 2006-01-27 | Idaho Res Foundation | Determination of pregnancy status in an ungulate animal |
| JPWO2003027151A1 (ja) * | 2001-09-25 | 2005-01-06 | 株式会社 免疫生物研究所 | 組換え抗オステオポンチン抗体およびその用途 |
| US7393696B2 (en) * | 2001-09-28 | 2008-07-01 | Aspenbio Pharma, Inc. | Bovine pregnancy test |
| EP1468288A4 (en) * | 2001-11-20 | 2006-03-15 | Univ Missouri | COMPOSITIONS AND METHODS FOR ACCURATE EARLY DIAGNOSIS OF A PREGNANCY |
| WO2006035386A2 (en) * | 2004-09-29 | 2006-04-06 | Koninklijke Philips Electronics N.V. | Smart handbag |
| US8192946B2 (en) * | 2008-04-10 | 2012-06-05 | The Curators Of The University Of Missouri | Assays for detecting pregnancy-associated glycoproteins |
-
2008
- 2008-12-12 WO PCT/US2008/086674 patent/WO2009076632A1/en not_active Ceased
- 2008-12-12 EP EP08860515.9A patent/EP2225274B1/en active Active
- 2008-12-12 BR BRPI0820885A patent/BRPI0820885B8/pt active IP Right Grant
- 2008-12-12 HU HUE08860515A patent/HUE034401T2/en unknown
- 2008-12-12 NZ NZ586100A patent/NZ586100A/en unknown
- 2008-12-12 AU AU2008334976A patent/AU2008334976B2/en active Active
- 2008-12-12 JP JP2010538206A patent/JP5679818B2/ja active Active
- 2008-12-12 US US12/747,514 patent/US8431349B2/en active Active
- 2008-12-12 DK DK08860515.9T patent/DK2225274T3/en active
- 2008-12-12 CA CA2709305A patent/CA2709305C/en active Active
- 2008-12-12 CN CN200880124722.0A patent/CN101918445B/zh active Active
- 2008-12-12 ES ES08860515.9T patent/ES2623459T3/es active Active
- 2008-12-12 KR KR1020107015367A patent/KR101637613B1/ko active Active
-
2010
- 2010-06-24 ZA ZA2010/04487A patent/ZA201004487B/en unknown
- 2010-07-13 CO CO10085345A patent/CO6280567A2/es active IP Right Grant
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