|
US4521210A
(en)
|
1982-12-27 |
1985-06-04 |
Wong Vernon G |
Eye implant for relieving glaucoma, and device and method for use therewith
|
|
US4997652A
(en)
|
1987-12-22 |
1991-03-05 |
Visionex |
Biodegradable ocular implants
|
|
US4853224A
(en)
|
1987-12-22 |
1989-08-01 |
Visionex |
Biodegradable ocular implants
|
|
US5164188A
(en)
|
1989-11-22 |
1992-11-17 |
Visionex, Inc. |
Biodegradable ocular implants
|
|
JPH0874B2
(ja)
|
1990-07-27 |
1996-01-10 |
アイシス・ファーマシューティカルス・インコーポレーテッド |
遺伝子発現を検出および変調するヌクレアーゼ耐性、ピリミジン修飾オリゴヌクレオチド
|
|
KR0185215B1
(ko)
|
1990-11-30 |
1999-05-01 |
요시다 쇼오지 |
서방성 안구삽입용 약제
|
|
JP3131222B2
(ja)
|
1991-12-24 |
2001-01-31 |
アイシス・ファーマシューティカルス・インコーポレーテッド |
ギャップを有する２′修飾オリゴヌクレオチド
|
|
US5874082A
(en)
*
|
1992-07-09 |
1999-02-23 |
Chiron Corporation |
Humanized anti-CD40 monoclonal antibodies and fragments capable of blocking B cell proliferation
|
|
ATE299509T1
(de)
|
1992-07-23 |
2005-07-15 |
Isis Pharmaceuticals Inc |
Neue 2'-o-alkyl-nukleoside und -phosphoramidite, verfahren zu ihrer herstellung und ihre verwendungen
|
|
WO1994019023A1
(en)
|
1993-02-19 |
1994-09-01 |
Isis Pharmaceuticals, Inc. |
Cyclobutyl antisense oligonucleotides, methods of making and use thereof
|
|
WO1995003009A1
(en)
|
1993-07-22 |
1995-02-02 |
Oculex Pharmaceuticals, Inc. |
Method of treatment of macular degeneration
|
|
US5443505A
(en)
|
1993-11-15 |
1995-08-22 |
Oculex Pharmaceuticals, Inc. |
Biocompatible ocular implants
|
|
US5869079A
(en)
|
1995-06-02 |
1999-02-09 |
Oculex Pharmaceuticals, Inc. |
Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
|
|
US6369116B1
(en)
|
1995-06-02 |
2002-04-09 |
Oculex Pharmaceuticals, Inc. |
Composition and method for treating glaucoma
|
|
US6506770B1
(en)
|
1996-06-06 |
2003-01-14 |
Anormed, Inc. |
Antiviral compounds
|
|
US5994515A
(en)
|
1996-06-25 |
1999-11-30 |
Trustees Of The University Of Pennsylvania |
Antibodies directed against cellular coreceptors for human immunodeficiency virus and methods of using the same
|
|
JP2001513369A
(ja)
|
1997-08-11 |
2001-09-04 |
アラーガン・セイルズ・インコーポレイテッド |
改善された生物適合性を有する無菌の生物侵食性の移植デバイスおよび方法
|
|
AU763325B2
(en)
|
1998-01-15 |
2003-07-17 |
King's College London |
Ribozymal nucleic acids cleaving CCR5 or CXCR4
|
|
CA2245224A1
(en)
|
1998-08-14 |
2000-02-14 |
Jiang-Hong Giong |
Chemokine receptor antagonists and chemotherapeutics
|
|
CA2305787A1
(en)
|
2000-05-09 |
2001-11-09 |
The University Of British Columbia |
Cxcr4 antagonist treatment of hematopoietic cells
|
|
JP2002506830A
(ja)
*
|
1998-03-13 |
2002-03-05 |
ザ ユニバーシティ オブ ブリティッシュ コロンビア |
治療的ケモカイン受容体アンタゴニスト
|
|
AU2855399A
(en)
|
1998-03-24 |
1999-10-18 |
Chugai Seiyaku Kabushiki Kaisha |
Vascularization inhibitors
|
|
WO1999062535A2
(en)
|
1998-06-01 |
1999-12-09 |
University Of Maryland Biotechnology Institute |
Receptor ligand antagonist complexes and their use in treating or preventing receptor mediated diseases
|
|
US20050202005A1
(en)
|
1998-07-31 |
2005-09-15 |
The Trustees Of Columbia University In The City Of New York |
Uses of inhibitors for the activation of CXCR4 receptor by SDF-1 in treating rheumatoid arthritis
|
|
WO2000006086A2
(en)
|
1998-07-31 |
2000-02-10 |
The Trustees Of Columbia University In The City Of New York |
Use of inhibitors of the activation of cxcr4 receptor by sdf-1 in treating rheumatoid arthritis
|
|
US20030099645A1
(en)
|
2000-10-10 |
2003-05-29 |
Lobo Peter Isaac |
Naturally occuring IgM antibodies that bind to membrane receptors on lymphocytes
|
|
US6610834B1
(en)
|
1998-11-18 |
2003-08-26 |
Peter I. Lobo |
Human IgM antibodies to chemokine receptors
|
|
US20050220787A1
(en)
|
2002-11-07 |
2005-10-06 |
Lobo Peter I |
Naturally occuring IgM antibodies that bind to lymphocytes
|
|
US6429308B1
(en)
|
1998-11-24 |
2002-08-06 |
Hisamitsu Pharmaceutical Co., Inc. |
HIV infection inhibitors
|
|
CA2704600C
(en)
|
1999-04-09 |
2016-10-25 |
Kyowa Kirin Co., Ltd. |
A method for producing antibodies with increased adcc activity
|
|
US6331313B1
(en)
|
1999-10-22 |
2001-12-18 |
Oculex Pharmaceticals, Inc. |
Controlled-release biocompatible ocular drug delivery implant devices and methods
|
|
US6949243B1
(en)
|
1999-11-24 |
2005-09-27 |
Schering Corporation |
Methods of inhibiting metastasis
|
|
AU2334301A
(en)
|
1999-12-17 |
2001-06-25 |
Anormed Inc. |
Chemokine receptor binding heterocyclic compounds
|
|
US20030220482A1
(en)
|
2000-02-03 |
2003-11-27 |
Ziwei Huang |
Novel peptide antagonist of CXCR4 derived from the N-terminus of the viral chemokine vMIP-II
|
|
CA2399032A1
(en)
|
2000-02-04 |
2001-08-09 |
The Government Of The United States Of America |
Ligands for fpr class receptors that induce a host immune response to a pathogen or inhibit hiv infection
|
|
US6726918B1
(en)
|
2000-07-05 |
2004-04-27 |
Oculex Pharmaceuticals, Inc. |
Methods for treating inflammation-mediated conditions of the eye
|
|
DE60137435D1
(de)
|
2000-09-15 |
2009-03-05 |
Anormed Inc |
Chemokin rezeptor bindenden heterozyklische verbindungen
|
|
US20030165988A1
(en)
|
2002-02-08 |
2003-09-04 |
Shaobing Hua |
High throughput generation of human monoclonal antibody against peptide fragments derived from membrane proteins
|
|
EP1339438B1
(en)
|
2000-11-29 |
2005-10-19 |
Allergan Inc. |
Preventing transplant rejection in the eye
|
|
US20060019917A1
(en)
|
2001-05-18 |
2006-01-26 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of stromal cell-derived factor-1 (SDF-1) gene expression using short interfering nucleic acid (siNA)
|
|
US20050124569A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)
|
|
US20040157818A1
(en)
|
2001-05-24 |
2004-08-12 |
Mikiro Yanaka |
Cxcr4-antagonistic drugs composed of nitrogen-containing compound
|
|
US20040254221A1
(en)
|
2001-09-28 |
2004-12-16 |
Toru Yamazaki |
Novel Nitrogenous Compound and use thereof
|
|
PL369856A1
(en)
|
2001-12-21 |
2005-05-02 |
Anormed Inc. |
Chemokine receptor binding heterocyclic compounds with enhanced efficacy
|
|
US7354932B2
(en)
|
2001-12-21 |
2008-04-08 |
Anormed, Inc. |
Chemokine receptor binding heterocyclic compounds with enhanced efficacy
|
|
AU2002356400A1
(en)
|
2001-12-31 |
2003-07-30 |
Consejo Superior De Investigaciones Cientificas |
Functional inactivation of cxcr4-mediated responses in growth hormone transgenic mice through socs3 upregulation
|
|
AU2003228667A1
(en)
*
|
2002-04-22 |
2003-12-19 |
Sirna Therapeutics Inc. |
Nucleic acid mediated disruption of hiv fusogenic peptide interactions
|
|
WO2003097854A2
(en)
|
2002-05-17 |
2003-11-27 |
Sugen, Inc. |
Novel biomarkers of tyrosine kinase inhibitor exposure and activity in mammals
|
|
US7148342B2
(en)
*
|
2002-07-24 |
2006-12-12 |
The Trustees Of The University Of Pennyslvania |
Compositions and methods for sirna inhibition of angiogenesis
|
|
US20050002939A1
(en)
|
2002-12-23 |
2005-01-06 |
Albert Zlotnik |
Tumor killing/tumor regression using CXCR4 antagonists
|
|
JP2006524242A
(ja)
*
|
2003-03-27 |
2006-10-26 |
エモリー ユニバーシティー |
Ｃｘｃｒ４アンタゴニストおよびそれらの使用方法
|
|
WO2004091518A2
(en)
|
2003-04-11 |
2004-10-28 |
Anormed Inc. |
Cxcr4 chemokine receptor binding compounds
|
|
WO2005002522A2
(en)
|
2003-06-30 |
2005-01-13 |
Caritas St. Elizabeth's Medical Center Of Boston, Inc. |
Compositions and methods for treating tissue ischemia
|
|
US20050266009A1
(en)
|
2003-06-30 |
2005-12-01 |
Savient Pharmaceuticals, Inc. |
Antibodies and uses thereof
|
|
US20050019927A1
(en)
|
2003-07-13 |
2005-01-27 |
Markus Hildinger |
DECREASING GENE EXPRESSION IN A MAMMALIAN SUBJECT IN VIVO VIA AAV-MEDIATED RNAi EXPRESSION CASSETTE TRANSFER
|
|
WO2005080410A1
(en)
|
2004-02-20 |
2005-09-01 |
Genesis Research And Development Corporation Limited |
Targeted delivery of rna interference molecules for the treatment of ige-mediated disorders
|
|
JP4939396B2
(ja)
|
2004-03-26 |
2012-05-23 |
ノヴァレメッド リミテッド |
Ａｉｄｓ及び他のウイルス性疾患及びｈｉｖ関連感染症の改善又はその治療用化合物及びそのような化合物を含む組成物、そのような疾患及び感染症の治療方法及びそのような化合物及び組成物の製造方法
|
|
US20080096859A1
(en)
*
|
2004-10-01 |
2008-04-24 |
Sullivan Kathleen A |
Compositions and Methods for Treating Ophthalmic Diseases
|
|
MX2007006214A
(es)
|
2004-11-24 |
2008-04-16 |
Therakine Ltd |
Un implante para suministro de farmaco intraocular.
|
|
EP1838320B1
(en)
*
|
2005-01-07 |
2014-07-16 |
Emory University |
Cxcr4 antagonists for the treatment of medical disorders
|
|
AU2006203826A1
(en)
*
|
2005-01-07 |
2006-07-13 |
Emory University |
CXCR4 antagonists for the treatment of HIV infection
|
|
WO2006090853A1
(ja)
|
2005-02-25 |
2006-08-31 |
Ono Pharmaceutical Co., Ltd. |
含窒素複素環化合物およびその医薬用途
|
|
US20060257359A1
(en)
*
|
2005-02-28 |
2006-11-16 |
Cedric Francois |
Modifying macrophage phenotype for treatment of disease
|
|
JP2008537551A
(ja)
*
|
2005-03-31 |
2008-09-18 |
カランド ファーマシューティカルズ， インコーポレイテッド |
リボヌクレオチドレダクターゼサブユニット２の阻害剤およびその使用
|