JP2008529502A - 細胞及び生物の寿命を延ばし、ストレス耐性を高めるための方法及び組成物 - Google Patents
細胞及び生物の寿命を延ばし、ストレス耐性を高めるための方法及び組成物 Download PDFInfo
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- JP2008529502A JP2008529502A JP2007554337A JP2007554337A JP2008529502A JP 2008529502 A JP2008529502 A JP 2008529502A JP 2007554337 A JP2007554337 A JP 2007554337A JP 2007554337 A JP2007554337 A JP 2007554337A JP 2008529502 A JP2008529502 A JP 2008529502A
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
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- Biomedical Technology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/053,185 US7977049B2 (en) | 2002-08-09 | 2005-02-08 | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| PCT/US2006/004397 WO2006086454A2 (en) | 2005-02-08 | 2006-02-08 | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012104652A Division JP2012176962A (ja) | 2005-02-08 | 2012-05-01 | 細胞及び生物の寿命を延ばし、ストレス耐性を高めるための方法及び組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2008529502A true JP2008529502A (ja) | 2008-08-07 |
Family
ID=36591266
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007554337A Pending JP2008529502A (ja) | 2005-02-08 | 2006-02-08 | 細胞及び生物の寿命を延ばし、ストレス耐性を高めるための方法及び組成物 |
| JP2012104652A Pending JP2012176962A (ja) | 2005-02-08 | 2012-05-01 | 細胞及び生物の寿命を延ばし、ストレス耐性を高めるための方法及び組成物 |
| JP2015098029A Pending JP2015180657A (ja) | 2005-02-08 | 2015-05-13 | 細胞及び生物の寿命を延ばし、ストレス耐性を高めるための方法及び組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012104652A Pending JP2012176962A (ja) | 2005-02-08 | 2012-05-01 | 細胞及び生物の寿命を延ばし、ストレス耐性を高めるための方法及び組成物 |
| JP2015098029A Pending JP2015180657A (ja) | 2005-02-08 | 2015-05-13 | 細胞及び生物の寿命を延ばし、ストレス耐性を高めるための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7977049B2 (https=) |
| EP (1) | EP1851240B1 (https=) |
| JP (3) | JP2008529502A (https=) |
| AU (1) | AU2006212770B2 (https=) |
| CA (1) | CA2595495C (https=) |
| ES (1) | ES2401342T3 (https=) |
| WO (1) | WO2006086454A2 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016538271A (ja) * | 2013-10-30 | 2016-12-08 | クロマデックス, インコーポレイテッドChromaDex, Inc. | 皮膚症状の治療において局所使用されるニコチンアミドリボシド組成物 |
| JP2018515487A (ja) * | 2015-05-01 | 2018-06-14 | ザ プロクター アンド ギャンブル カンパニー | 皮膚の健康を改善する方法及びそのための組成物 |
| JP2022544776A (ja) * | 2019-08-14 | 2022-10-21 | メトロ インターナショナル バイオテック,エルエルシー | ニコチンアミドアデニンジヌクレオチドの差次的モジュレーションのための化合物及び組成物 |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2421269A1 (en) * | 2002-08-09 | 2004-02-09 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| CA2529510A1 (en) | 2003-07-01 | 2005-01-13 | President And Fellows Of Harvard College | Compositions for manipulating the lifespan and stress response of cells and organisms |
| US20060025337A1 (en) * | 2003-07-01 | 2006-02-02 | President And Fellows Of Harvard College | Sirtuin related therapeutics and diagnostics for neurodegenerative diseases |
| EP1708689A2 (en) | 2003-12-29 | 2006-10-11 | The President and Fellows of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
| US8017634B2 (en) | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| US20090117543A1 (en) * | 2004-05-04 | 2009-05-07 | President And Fellows Of Harvard College | Methods and compositions for inducing sirtuins |
| JP2008501343A (ja) * | 2004-06-04 | 2008-01-24 | ワシントン・ユニバーシティ | 神経障害を治療するための方法および組成物 |
| PL1794306T3 (pl) * | 2004-09-24 | 2010-05-31 | Bayer Cropscience Nv | Rośliny oporne na stres |
| JP2008527002A (ja) * | 2005-01-13 | 2008-07-24 | サートリス ファーマシューティカルズ, インコーポレイテッド | 神経変性障害および血液凝固障害を予防および処置するための新規組成物 |
| US20070014833A1 (en) * | 2005-03-30 | 2007-01-18 | Sirtris Pharmaceuticals, Inc. | Treatment of eye disorders with sirtuin modulators |
| US20060229265A1 (en) * | 2005-03-30 | 2006-10-12 | Sirtris Pharmaceuticals, Inc. | Nicotinamide riboside and analogues thereof |
| WO2007084162A2 (en) * | 2005-04-08 | 2007-07-26 | President And Fellows Of Harvard College | Sirtuin inhibiting compounds |
| US20060292099A1 (en) * | 2005-05-25 | 2006-12-28 | Michael Milburn | Treatment of eye disorders with sirtuin modulators |
| WO2006138418A2 (en) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| EP1757284A1 (en) * | 2005-08-25 | 2007-02-28 | Santhera Pharmaceuticals (Schweiz) AG | Use of N-(dibenz(b,f)oxepin-10ylmethyl)-N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of muscular dystrophy |
| EP3369738B1 (en) | 2005-11-18 | 2020-05-20 | Cornell Research Foundation, Inc. | Method for making nicotinoyl ribosides and nicotinamide beta-riboside |
| WO2007101122A2 (en) * | 2006-02-24 | 2007-09-07 | University Of Chicago | Methods and compositions involving slc17a1 |
| US8158856B2 (en) * | 2006-03-21 | 2012-04-17 | Bayer Cropscience Nv | Stress resistant plants |
| WO2007136744A1 (en) * | 2006-05-19 | 2007-11-29 | The Johns Hopkins University | Crystal structure of a substrate complex of nampt/pbef/visfatin |
| AU2008210327B2 (en) * | 2007-01-31 | 2011-06-16 | Methylation Sciences International Srl | Extended release pharmaceutical formulations of S-adenosylmethionine |
| US20090088404A1 (en) * | 2007-01-31 | 2009-04-02 | Methylation Sciences International Srl | Extended Release Pharmaceutical Formulations of S-Adenosylmethionine |
| US20090197824A1 (en) * | 2008-01-31 | 2009-08-06 | Methylation Sciences International Srl | Extended Release Pharmaceutical Formulations of S-Adenosylmethionine |
| WO2008095056A2 (en) * | 2007-02-01 | 2008-08-07 | The Wistar Institute | Method for identifying a compound that modulates sir2 protein activity |
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| EP2222833A4 (en) * | 2007-11-30 | 2011-05-18 | Univ California | Industrial production of organic compounds using recombinant organisms expressing methyl halide transferase |
| JP5570731B2 (ja) * | 2008-02-28 | 2014-08-13 | 旭化成ファーマ株式会社 | ピロリン酸の測定方法 |
| AU2009322474A1 (en) * | 2008-12-01 | 2011-07-21 | Lifespan Extension Llc | Methods and compositions for altering health, wellbeing, and lifespan |
| US9162980B2 (en) | 2009-01-09 | 2015-10-20 | Board Of Regents Of The University Of Texas System | Anti-depression compounds |
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| CA2805041A1 (en) | 2009-07-22 | 2011-01-27 | The Regents Of The University Of California | Cell-based systems for production of methyl formate |
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| GB201007197D0 (en) * | 2010-04-30 | 2010-06-16 | Ge Healthcare Uk Ltd | Methods and kits for determining the toxicity of an agent |
| WO2012068463A2 (en) * | 2010-11-18 | 2012-05-24 | Beth Israel Deaconess Medicall Center, Inc. | Methods of treating obesity by inhibiting nicotinamide n-methyl transferase (nnmt) |
| EP3345901A3 (en) * | 2011-06-29 | 2018-09-12 | President and Fellows of Harvard College | Small molecules as antiaging agents |
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| WO2014059031A2 (en) * | 2012-10-09 | 2014-04-17 | President And Fellows Of Harvard College | Nad biosynthesis and precursors in the prevention and treatment of inflammation |
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| WO2015070234A2 (en) | 2013-11-11 | 2015-05-14 | Board Of Regents Of The University Of Texas System | Neuroprotective compounds and use thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2016538271A (ja) * | 2013-10-30 | 2016-12-08 | クロマデックス, インコーポレイテッドChromaDex, Inc. | 皮膚症状の治療において局所使用されるニコチンアミドリボシド組成物 |
| CN109985056A (zh) * | 2013-10-30 | 2019-07-09 | 可劳迈戴斯有限公司 | 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物 |
| US10688118B2 (en) | 2013-10-30 | 2020-06-23 | ChromaDex Inc. | Nicotinamide riboside compositions for topical use in treating skin conditions |
| US11033568B2 (en) | 2013-10-30 | 2021-06-15 | ChromaDex Inc. | Nicotinamide riboside compositions for topical use in treating skin conditions |
| JP2018515487A (ja) * | 2015-05-01 | 2018-06-14 | ザ プロクター アンド ギャンブル カンパニー | 皮膚の健康を改善する方法及びそのための組成物 |
| JP2022544776A (ja) * | 2019-08-14 | 2022-10-21 | メトロ インターナショナル バイオテック,エルエルシー | ニコチンアミドアデニンジヌクレオチドの差次的モジュレーションのための化合物及び組成物 |
| JP7702934B2 (ja) | 2019-08-14 | 2025-07-04 | メトロ インターナショナル バイオテック,エルエルシー | ニコチンアミドアデニンジヌクレオチドの差次的モジュレーションのための化合物及び組成物 |
Also Published As
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|---|---|
| ES2401342T3 (es) | 2013-04-18 |
| CA2595495C (en) | 2014-12-09 |
| EP1851240B1 (en) | 2012-12-12 |
| AU2006212770B2 (en) | 2013-04-04 |
| US20050267023A1 (en) | 2005-12-01 |
| JP2015180657A (ja) | 2015-10-15 |
| JP2012176962A (ja) | 2012-09-13 |
| WO2006086454A3 (en) | 2007-03-29 |
| WO2006086454A2 (en) | 2006-08-17 |
| AU2006212770A1 (en) | 2006-08-17 |
| CA2595495A1 (en) | 2006-08-17 |
| EP1851240A2 (en) | 2007-11-07 |
| US7977049B2 (en) | 2011-07-12 |
| US20120022013A1 (en) | 2012-01-26 |
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