IT1302365B1 - Uso di carnitine e resveratrolo per produrre una composizione per laprevenzione o il trattamento terapeutico di alterazioni cerebrali - Google Patents

Uso di carnitine e resveratrolo per produrre una composizione per laprevenzione o il trattamento terapeutico di alterazioni cerebrali

Info

Publication number
IT1302365B1
IT1302365B1 IT1998RM000636A ITRM980636A IT1302365B1 IT 1302365 B1 IT1302365 B1 IT 1302365B1 IT 1998RM000636 A IT1998RM000636 A IT 1998RM000636A IT RM980636 A ITRM980636 A IT RM980636A IT 1302365 B1 IT1302365 B1 IT 1302365B1
Authority
IT
Italy
Prior art keywords
resveratrol
carnitine
prevention
produce
composition
Prior art date
Application number
IT1998RM000636A
Other languages
English (en)
Inventor
Claudio Cavazza
Original Assignee
Sigma Tau Healthscience Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Healthscience Spa filed Critical Sigma Tau Healthscience Spa
Priority to IT1998RM000636A priority Critical patent/IT1302365B1/it
Priority to TNTNSN99186A priority patent/TNSN99186A1/fr
Priority to EEP200100205A priority patent/EE200100205A/xx
Priority to HU0104021A priority patent/HU229364B1/hu
Priority to AU61213/99A priority patent/AU767492B2/en
Priority to CA002344893A priority patent/CA2344893C/en
Priority to TR2001/00947T priority patent/TR200100947T2/xx
Priority to BR9915918-0A priority patent/BR9915918A/pt
Priority to CZ2001920A priority patent/CZ2001920A3/cs
Priority to AT99947853T priority patent/ATE249823T1/de
Priority to US09/806,454 priority patent/US6515020B1/en
Priority to PT99947853T priority patent/PT1117394E/pt
Priority to EP99947853A priority patent/EP1117394B1/en
Priority to IL14204699A priority patent/IL142046A0/xx
Priority to DK99947853T priority patent/DK1117394T3/da
Priority to KR1020017004267A priority patent/KR20010079981A/ko
Priority to SK378-2001A priority patent/SK3782001A3/sk
Priority to PCT/IT1999/000311 priority patent/WO2000021526A1/en
Priority to DE69911441T priority patent/DE69911441T2/de
Priority to ES99947853T priority patent/ES2207287T3/es
Priority to JP2000575502A priority patent/JP4166951B2/ja
Priority to CN99811952A priority patent/CN1323205A/zh
Priority to PL347209A priority patent/PL197342B1/pl
Priority to ARP990105115A priority patent/AR020762A1/es
Publication of ITRM980636A1 publication Critical patent/ITRM980636A1/it
Application granted granted Critical
Publication of IT1302365B1 publication Critical patent/IT1302365B1/it
Priority to IS5896A priority patent/IS5896A/is
Priority to NO20011693A priority patent/NO20011693D0/no
Priority to HK02102885.2A priority patent/HK1040935A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
IT1998RM000636A 1998-10-09 1998-10-09 Uso di carnitine e resveratrolo per produrre una composizione per laprevenzione o il trattamento terapeutico di alterazioni cerebrali IT1302365B1 (it)

Priority Applications (27)

Application Number Priority Date Filing Date Title
IT1998RM000636A IT1302365B1 (it) 1998-10-09 1998-10-09 Uso di carnitine e resveratrolo per produrre una composizione per laprevenzione o il trattamento terapeutico di alterazioni cerebrali
TNTNSN99186A TNSN99186A1 (fr) 1998-10-09 1999-10-05 Utilisation des carnitines et du resveratrol pour produire une composition pour la prevention ou le traitement therapeutique des troubles cerebraux dus au vieillissements et a l'utilisation des substances neurotoxiques
KR1020017004267A KR20010079981A (ko) 1998-10-09 1999-10-06 대뇌 및 노화 질환의 예방 또는 치료를 위한 카르니틴과레스베라트롤의 복합물
AU61213/99A AU767492B2 (en) 1998-10-09 1999-10-06 Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
CA002344893A CA2344893C (en) 1998-10-09 1999-10-06 Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
TR2001/00947T TR200100947T2 (tr) 1998-10-09 1999-10-06 Karnitinler ve resveratrol kombinasyonu.
BR9915918-0A BR9915918A (pt) 1998-10-09 1999-10-06 Combinação de carnitinas e resveratrol para prevenção ou tratamento de distúrbios cerebrais ou de envelhecimento
CZ2001920A CZ2001920A3 (cs) 1998-10-09 1999-10-06 Kombinace karnitinů a resveratrolu k prevenci nebo léčbě poruch mozku a poruch spojených se stárnutím
AT99947853T ATE249823T1 (de) 1998-10-09 1999-10-06 Verwendung von carnitinen und resveratrol zur herstellung einer zusammensetzung zur verhinderung oder behandlung von zerebralenerkrankungen verursacht durch alterung und verwendung neurotoxischer mittel
US09/806,454 US6515020B1 (en) 1998-10-09 1999-10-06 Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
PT99947853T PT1117394E (pt) 1998-10-09 1999-10-06 Utilizacao de carnitinas e resveratrol para produzir uma composicao para a prevencao ou tratamento terapeutico de desordens cerebrais provocadas por envelhecimento e uso de drogas neurotoxicas
EP99947853A EP1117394B1 (en) 1998-10-09 1999-10-06 Use of carnitines and resveratrol to produce a composition for the prevention or therapeutic treatment of cerebral disorders brought about by ageing and use of neurotoxic drugs
EEP200100205A EE200100205A (et) 1998-10-09 1999-10-06 Karnitiinide ning resveratrooli kombinatsioon tserebraalsete ning vananemisest tingitud haiguste ennetamiseks või raviks
DK99947853T DK1117394T3 (da) 1998-10-09 1999-10-06 Anvendelse af carnitiner og resveratrol til fremstilling af et præparat til forebyggelse eller terapeutisk behandling af cerabrale lidelser forårsaget af aldring og anvendelse af neurotoksiske medikamenter
HU0104021A HU229364B1 (en) 1998-10-09 1999-10-06 Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
SK378-2001A SK3782001A3 (en) 1998-10-09 1999-10-06 Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
PCT/IT1999/000311 WO2000021526A1 (en) 1998-10-09 1999-10-06 Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
DE69911441T DE69911441T2 (de) 1998-10-09 1999-10-06 Verwendung von carnitinen und resveratrol zur herstellung einer zusammensetzung zur verhinderung oder behandlung von zerebralenerkrankungen verursacht durch alterung und verwendung neurotoxischer mittel
ES99947853T ES2207287T3 (es) 1998-10-09 1999-10-06 Uso de carnitinas y resveratrol para producir una composicion para la prevencion o tratamiento terapeutico de trastornos cerebrales producidos por el envejecimiento y uso de farmacos neurotoxicos.
JP2000575502A JP4166951B2 (ja) 1998-10-09 1999-10-06 脳性および加齢性疾患の予防または治療のためのカルニチンおよびレスベラトロールの組み合わせ
CN99811952A CN1323205A (zh) 1998-10-09 1999-10-06 预防或治疗大脑和老化疾病的肉毒碱和白藜芦醇的复方
PL347209A PL197342B1 (pl) 1998-10-09 1999-10-06 Zastosowanie L-karnityny lub alkanoilo-L-karnityny oraz trihydroksystylbenu lub tetrahydroksystylbenu
IL14204699A IL142046A0 (en) 1998-10-09 1999-10-06 Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
ARP990105115A AR020762A1 (es) 1998-10-09 1999-10-08 El uso de carnitina y resveratrol para producir una composicion para la prevencion o el tratamiento terapeutico de los trastornos cerebrales provocados porel envejecimiento y el uso de drogas neurotoxicas
IS5896A IS5896A (is) 1998-10-09 2001-03-16 Karnitín og resveratról samsetning til hindrnar eða meðhöndlunar á heila- og öldrunarkvillum
NO20011693A NO20011693D0 (no) 1998-10-09 2001-04-04 Kombinasjon av karnitiner og resveratrol for forebygging eller behandling av cerebrale og aldringsforstyrrelser
HK02102885.2A HK1040935A1 (zh) 1998-10-09 2002-04-17 預防或治療大腦和老化疾病的肉毒碱和白藜蘆醇的複方

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998RM000636A IT1302365B1 (it) 1998-10-09 1998-10-09 Uso di carnitine e resveratrolo per produrre una composizione per laprevenzione o il trattamento terapeutico di alterazioni cerebrali

Publications (2)

Publication Number Publication Date
ITRM980636A1 ITRM980636A1 (it) 2000-04-10
IT1302365B1 true IT1302365B1 (it) 2000-09-05

Family

ID=11406160

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998RM000636A IT1302365B1 (it) 1998-10-09 1998-10-09 Uso di carnitine e resveratrolo per produrre una composizione per laprevenzione o il trattamento terapeutico di alterazioni cerebrali

Country Status (27)

Country Link
US (1) US6515020B1 (it)
EP (1) EP1117394B1 (it)
JP (1) JP4166951B2 (it)
KR (1) KR20010079981A (it)
CN (1) CN1323205A (it)
AR (1) AR020762A1 (it)
AT (1) ATE249823T1 (it)
AU (1) AU767492B2 (it)
BR (1) BR9915918A (it)
CA (1) CA2344893C (it)
CZ (1) CZ2001920A3 (it)
DE (1) DE69911441T2 (it)
DK (1) DK1117394T3 (it)
EE (1) EE200100205A (it)
ES (1) ES2207287T3 (it)
HK (1) HK1040935A1 (it)
HU (1) HU229364B1 (it)
IL (1) IL142046A0 (it)
IS (1) IS5896A (it)
IT (1) IT1302365B1 (it)
NO (1) NO20011693D0 (it)
PL (1) PL197342B1 (it)
PT (1) PT1117394E (it)
SK (1) SK3782001A3 (it)
TN (1) TNSN99186A1 (it)
TR (1) TR200100947T2 (it)
WO (1) WO2000021526A1 (it)

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JP2002047193A (ja) * 2000-07-31 2002-02-12 Sunstar Inc アレルギー性皮膚炎予防または治療用組成物
US20020173511A1 (en) * 2000-11-08 2002-11-21 Wurtman Richard J. Serotonergic compositions and methods for treatment of mild cognitive impairment
BRPI0106382B1 (pt) * 2001-03-13 2017-07-11 Universidade Do Estado Do Rio De Janeiro - Uerj Process for obtaining decocts from vitis labrusca and vitis vinifera casts, process for obtaining the hydro-alcoholic extract, process for obtaining the hydro-alcoholic extract-ethyl acetate and pharmaceutical compositions
ATE342044T1 (de) * 2001-08-18 2006-11-15 Cognis Ip Man Gmbh Wirkstoffmischungen
US20070218151A1 (en) * 2002-03-12 2007-09-20 Universidade Do Estado Do Rio De Janeiro Process for obtention of decoctions of Vitis labrusca and Vitis vinifera skins
US7977049B2 (en) * 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
KR100574392B1 (ko) * 2003-02-07 2006-05-02 재단법인서울대학교산학협력재단 신경보호활성을 갖는 신규 페닐환 유도체 및 이를함유하는 약학 조성물
WO2005002672A2 (en) * 2003-07-01 2005-01-13 President And Fellows Of Harvard College Sirt1 modulators for manipulating cells/organism lifespan/stress response
US20060025337A1 (en) * 2003-07-01 2006-02-02 President And Fellows Of Harvard College Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
KR100543056B1 (ko) * 2003-11-07 2006-01-20 (주)네추럴에프앤피 신경세포 보호 활성이 있는 포도씨 추출물을 포함하는뇌질환 예방 및 치료용 조성물
AU2004312072B2 (en) 2003-12-29 2011-06-23 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
ES2245609B1 (es) * 2004-06-18 2007-08-16 Universidad De Barcelona Nuevo agente terapeutico para el tratamiento de la infertilidad y/o subfertilidad masculina en mamiferos.
WO2006004722A2 (en) * 2004-06-30 2006-01-12 Biomol Research Laboratories, Inc. Compositions and methods for selectively activating human sirtuins
US20060121137A1 (en) * 2004-12-07 2006-06-08 Hartle Diane K Muscadine grape pomace in the treatment of intestinal inflammation
JP2008527002A (ja) * 2005-01-13 2008-07-24 サートリス ファーマシューティカルズ， インコーポレイテッド 神経変性障害および血液凝固障害を予防および処置するための新規組成物
WO2006138418A2 (en) * 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
EP2322158B1 (en) 2005-10-26 2020-06-10 Kao Corporation Resveratrol and/or grape leaf extract for energy metabolism activation
FR2898493B1 (fr) * 2006-03-16 2008-08-08 Af Consulting Compositions cosmetiques, pharmaceutiques, alimentaires et veterinaires dont l'action d'activation de genes de type sirtuin permet de retarder le vieillissement des mammiferes et ses effets nefastes
US20120016037A1 (en) * 2006-07-24 2012-01-19 Frank Toppo Method for prevention and treatment of Alzheimers
CA2676609A1 (en) * 2007-01-26 2008-07-31 Washington University Methods and compositions for treating neuropathies
AT506014A1 (de) * 2007-10-24 2009-05-15 Karl Mag Dr Zehethofer Functional drink
JP2013530170A (ja) * 2010-06-16 2013-07-25 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 神経組織における神経発生を増大させるための方法における使用のためのアセチル−カルニチン
KR101327936B1 (ko) * 2011-07-06 2013-11-13 한국식품연구원 옥시레스베라트롤 이민 유도체를 유효성분으로 함유하는 뇌신경보호 효과를 가지는 조성물
CN102919943A (zh) * 2012-10-26 2013-02-13 郑全辉 保健饮品-葡藤素
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Also Published As

Publication number Publication date
DE69911441D1 (de) 2003-10-23
EP1117394A1 (en) 2001-07-25
JP2002527389A (ja) 2002-08-27
HUP0104021A3 (en) 2003-12-29
TNSN99186A1 (fr) 2005-11-10
EP1117394B1 (en) 2003-09-17
CA2344893A1 (en) 2000-04-20
CN1323205A (zh) 2001-11-21
HU229364B1 (en) 2013-11-28
NO20011693L (no) 2001-04-04
JP4166951B2 (ja) 2008-10-15
DE69911441T2 (de) 2004-07-01
KR20010079981A (ko) 2001-08-22
AU767492B2 (en) 2003-11-13
US6515020B1 (en) 2003-02-04
EE200100205A (et) 2002-06-17
HK1040935A1 (zh) 2002-06-28
SK3782001A3 (en) 2001-10-08
AR020762A1 (es) 2002-05-29
ES2207287T3 (es) 2004-05-16
CA2344893C (en) 2008-07-29
CZ2001920A3 (cs) 2001-08-15
ATE249823T1 (de) 2003-10-15
PL347209A1 (en) 2002-03-25
WO2000021526A1 (en) 2000-04-20
NO20011693D0 (no) 2001-04-04
HUP0104021A2 (hu) 2002-02-28
ITRM980636A1 (it) 2000-04-10
IS5896A (is) 2001-03-16
PT1117394E (pt) 2004-02-27
PL197342B1 (pl) 2008-03-31
TR200100947T2 (tr) 2001-07-23
DK1117394T3 (da) 2004-01-26
AU6121399A (en) 2000-05-01
IL142046A0 (en) 2002-03-10
BR9915918A (pt) 2001-08-21

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