JP2008526893A5 - - Google Patents

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Publication number
JP2008526893A5
JP2008526893A5 JP2007550575A JP2007550575A JP2008526893A5 JP 2008526893 A5 JP2008526893 A5 JP 2008526893A5 JP 2007550575 A JP2007550575 A JP 2007550575A JP 2007550575 A JP2007550575 A JP 2007550575A JP 2008526893 A5 JP2008526893 A5 JP 2008526893A5
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JP
Japan
Prior art keywords
pharmaceutical composition
inhalable
inhalable pharmaceutical
patient
insulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007550575A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008526893A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/000910 external-priority patent/WO2006086107A2/en
Publication of JP2008526893A publication Critical patent/JP2008526893A/ja
Publication of JP2008526893A5 publication Critical patent/JP2008526893A5/ja
Withdrawn legal-status Critical Current

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JP2007550575A 2005-01-10 2006-01-10 肺における吸入可能なインスリンの自然増加を最少化するための方法及び組成物 Withdrawn JP2008526893A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64305405P 2005-01-10 2005-01-10
PCT/US2006/000910 WO2006086107A2 (en) 2005-01-10 2006-01-10 Methods and compositions for minimizing accrual of inhalable insulin in the lungs

Publications (2)

Publication Number Publication Date
JP2008526893A JP2008526893A (ja) 2008-07-24
JP2008526893A5 true JP2008526893A5 (enExample) 2009-03-05

Family

ID=36793549

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007550575A Withdrawn JP2008526893A (ja) 2005-01-10 2006-01-10 肺における吸入可能なインスリンの自然増加を最少化するための方法及び組成物

Country Status (7)

Country Link
US (1) US20060153778A1 (enExample)
EP (1) EP1858486A2 (enExample)
JP (1) JP2008526893A (enExample)
AU (1) AU2006213084A1 (enExample)
CA (1) CA2592776A1 (enExample)
MX (1) MX2007008379A (enExample)
WO (1) WO2006086107A2 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2280004B1 (en) 1999-06-29 2016-04-20 MannKind Corporation Pharmaceutical formulations comprising insulin complexed with a diketopiperazine
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
EP1494732B1 (en) 2002-03-20 2008-01-30 MannKind Corporation Inhalation apparatus
US20070027063A1 (en) * 2004-01-12 2007-02-01 Mannkind Corporation Method of preserving the function of insulin-producing cells
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
AU2014271222B2 (en) * 2005-09-14 2016-04-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
AU2006290227B2 (en) 2005-09-14 2012-08-02 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
KR101736502B1 (ko) * 2007-10-24 2017-05-16 맨카인드 코포레이션 Glp-1에 의한 유해 효과의 예방 방법
SG10201507036TA (en) 2008-06-13 2015-10-29 Mannkind Corp A dry powder inhaler and system for drug delivery
US20190262557A1 (en) * 2010-03-04 2019-08-29 Mannkind Corporation Dry powder drug delivery system
US8485180B2 (en) * 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
US11110151B2 (en) * 2008-08-11 2021-09-07 Mannkind Corporation Composition and method for reducing hypoglycemia events in diabetes treatment
TWI614024B (zh) * 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
MX2011007371A (es) * 2009-01-08 2011-09-06 Mannkind Corp Metodo para tratar la hiperglucemia con la molecula.
MX2011009251A (es) * 2009-03-04 2011-11-18 Mannkind Corp Sistema mejorado de suministro de farmaco en polvo seco.
AU2014200960B2 (en) * 2009-03-04 2016-02-11 Mannkind Corporation An improved dry powder drug delivery system
MX2011009512A (es) 2009-03-11 2011-11-29 Mannkind Corp Aparato, sistema y metodo para medir la resistencia de un inhalador.
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
MY172858A (en) * 2009-06-12 2019-12-12 Mannkind Corp Diketopiperazine microparticles with defined isomer contents
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1200318A1 (en) 2011-10-24 2015-08-07 曼金德公司 Methods and compositions for treating pain
EP2872205B1 (en) 2012-07-12 2017-02-08 MannKind Corporation Dry powder drug delivery systems
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2000301A (en) * 1932-04-02 1935-05-07 Norman Confections Inc Progressive container
US5352461A (en) * 1992-03-11 1994-10-04 Pharmaceutical Discovery Corporation Self assembling diketopiperazine drug delivery system
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5547929A (en) * 1994-09-12 1996-08-20 Eli Lilly And Company Insulin analog formulations
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
EP2280004B1 (en) * 1999-06-29 2016-04-20 MannKind Corporation Pharmaceutical formulations comprising insulin complexed with a diketopiperazine
AU2005204378B2 (en) * 2004-01-12 2009-01-22 Mannkind Corporation A method of reducing serum proinsulin levels in type 2 diabetics

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