WO2005041922A3 - Composition - Google Patents

Composition Download PDF

Info

Publication number
WO2005041922A3
WO2005041922A3 PCT/GB2004/004511 GB2004004511W WO2005041922A3 WO 2005041922 A3 WO2005041922 A3 WO 2005041922A3 GB 2004004511 W GB2004004511 W GB 2004004511W WO 2005041922 A3 WO2005041922 A3 WO 2005041922A3
Authority
WO
WIPO (PCT)
Prior art keywords
dry powder
composition
inhalation
treatment
pharmaceutical compositions
Prior art date
Application number
PCT/GB2004/004511
Other languages
French (fr)
Other versions
WO2005041922A2 (en
Inventor
Andrew Bruce Brown
Anthony James Taylor
Oort Michiel Mary Van
Original Assignee
Glaxo Group Ltd
Andrew Bruce Brown
Anthony James Taylor
Oort Michiel Mary Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB0324897A priority Critical patent/GB0324897D0/en
Priority to GB0324897.8 priority
Application filed by Glaxo Group Ltd, Andrew Bruce Brown, Anthony James Taylor, Oort Michiel Mary Van filed Critical Glaxo Group Ltd
Publication of WO2005041922A2 publication Critical patent/WO2005041922A2/en
Publication of WO2005041922A3 publication Critical patent/WO2005041922A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043Non-destructive separation of the package, e.g. peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Abstract

Dry powder pharmaceutical compositions having improved storage stability, dry powder inhalers comprising the same and their use in the treatment of respiratory disorders by inhalation.
PCT/GB2004/004511 2003-10-24 2004-10-22 Composition WO2005041922A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB0324897A GB0324897D0 (en) 2003-10-24 2003-10-24 Composition
GB0324897.8 2003-10-24

Publications (2)

Publication Number Publication Date
WO2005041922A2 WO2005041922A2 (en) 2005-05-12
WO2005041922A3 true WO2005041922A3 (en) 2005-09-15

Family

ID=29595798

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2004/004511 WO2005041922A2 (en) 2003-10-24 2004-10-22 Composition

Country Status (2)

Country Link
GB (1) GB0324897D0 (en)
WO (1) WO2005041922A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8992983B2 (en) 2010-08-30 2015-03-31 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
US9061352B2 (en) 2010-08-30 2015-06-23 Pulmatrix, Inc. Dry powder formulations and methods for treating pulmonary diseases
US9433576B2 (en) 2010-09-29 2016-09-06 Pulmatrix, Inc. Cationic dry powders

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008540680A (en) * 2005-05-18 2008-11-20 プルマトリックス インコーポレイテッド Formulations for changing the biophysical properties of the mucosal lining
MX354829B (en) 2009-03-26 2018-03-22 Pulmatrix Operating Company Inc Dry powder formulations and methods for treating pulmonary diseases.
KR101915241B1 (en) 2010-09-29 2018-11-06 풀매트릭스 오퍼레이팅 컴퍼니, 인크 Monovalent metal cation dry powders for inhalation
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
CA2907566A1 (en) 2013-04-01 2014-10-09 Pulmatrix, Inc. Tiotropium dry powders
EP3277265A1 (en) * 2015-04-01 2018-02-07 Lupin Atlantis Holdings SA Process for manufacturing dry powder blends

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143440A (en) * 1966-07-21 1969-02-19 Merck & Co Inc Inhalation aerosol preparation
US4353365A (en) * 1979-12-06 1982-10-12 Glaxo Group Limited Device for dispensing medicaments
US4668218A (en) * 1985-04-12 1987-05-26 Aktiebolaget Draco Indicating means for a dosage dispensing device
US4811731A (en) * 1985-07-30 1989-03-14 Glaxo Group Limited Devices for administering medicaments to patients
WO1993001812A1 (en) * 1991-07-20 1993-02-04 Smithkline Beecham Plc S-(3-(4(5))-imidazolyl)propyl)isothiourea as selective trhistomine h3 receptor antagonist
US5873360A (en) * 1990-03-02 1999-02-23 Glaxo Group Limited Inhalation device
WO2000046147A2 (en) * 1999-02-03 2000-08-10 Biosante Pharmaceuticals, Inc. Therapeutic calcium phosphate particles and methods of manufacture and use
WO2000071419A1 (en) * 1999-05-21 2000-11-30 Glaxo Group Limited Method and apparatus for loading a container with a product
US6250300B1 (en) * 1992-12-11 2001-06-26 Ab Astra System for dispensing pharmaceutically active compounds

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143440A (en) * 1966-07-21 1969-02-19 Merck & Co Inc Inhalation aerosol preparation
US4353365A (en) * 1979-12-06 1982-10-12 Glaxo Group Limited Device for dispensing medicaments
US4668218A (en) * 1985-04-12 1987-05-26 Aktiebolaget Draco Indicating means for a dosage dispensing device
US4811731A (en) * 1985-07-30 1989-03-14 Glaxo Group Limited Devices for administering medicaments to patients
US5873360A (en) * 1990-03-02 1999-02-23 Glaxo Group Limited Inhalation device
WO1993001812A1 (en) * 1991-07-20 1993-02-04 Smithkline Beecham Plc S-(3-(4(5))-imidazolyl)propyl)isothiourea as selective trhistomine h3 receptor antagonist
US6250300B1 (en) * 1992-12-11 2001-06-26 Ab Astra System for dispensing pharmaceutically active compounds
WO2000046147A2 (en) * 1999-02-03 2000-08-10 Biosante Pharmaceuticals, Inc. Therapeutic calcium phosphate particles and methods of manufacture and use
WO2000071419A1 (en) * 1999-05-21 2000-11-30 Glaxo Group Limited Method and apparatus for loading a container with a product

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8992983B2 (en) 2010-08-30 2015-03-31 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
US9061352B2 (en) 2010-08-30 2015-06-23 Pulmatrix, Inc. Dry powder formulations and methods for treating pulmonary diseases
US9233158B2 (en) 2010-08-30 2016-01-12 Pulmatrix, Inc. Dry powder formulations and methods for treating pulmonary diseases
US9433576B2 (en) 2010-09-29 2016-09-06 Pulmatrix, Inc. Cationic dry powders

Also Published As

Publication number Publication date
WO2005041922A2 (en) 2005-05-12
GB0324897D0 (en) 2003-11-26

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