JP2008526760A - 種々の腫瘍関連抗原を含む組成物の抗癌ワクチンとしての使用 - Google Patents

種々の腫瘍関連抗原を含む組成物の抗癌ワクチンとしての使用 Download PDF

Info

Publication number
JP2008526760A
JP2008526760A JP2007549637A JP2007549637A JP2008526760A JP 2008526760 A JP2008526760 A JP 2008526760A JP 2007549637 A JP2007549637 A JP 2007549637A JP 2007549637 A JP2007549637 A JP 2007549637A JP 2008526760 A JP2008526760 A JP 2008526760A
Authority
JP
Japan
Prior art keywords
cancer
antigen
tumor
inducing
immune response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007549637A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008526760A5 (https=
Inventor
チャン,チー−シェン
ジェイ.エル. シマード,ジョン
シー. ダイアモンド,デイビッド
イオン ボット,アドリアン
リウ,シピン
Original Assignee
マンカインド コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マンカインド コーポレイション filed Critical マンカインド コーポレイション
Publication of JP2008526760A publication Critical patent/JP2008526760A/ja
Publication of JP2008526760A5 publication Critical patent/JP2008526760A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001154Enzymes
    • A61K39/001156Tyrosinase and tyrosinase related proteinases [TRP-1 or TRP-2]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001184Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001184Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001186MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001184Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001188NY-ESO
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001184Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001189PRAME
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/00119Melanoma antigens
    • A61K39/001191Melan-A/MART
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001193Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
    • A61K39/001195Prostate specific membrane antigen [PSMA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP2007549637A 2004-12-29 2005-12-29 種々の腫瘍関連抗原を含む組成物の抗癌ワクチンとしての使用 Pending JP2008526760A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64059804P 2004-12-29 2004-12-29
PCT/US2005/047407 WO2006071983A2 (en) 2004-12-29 2005-12-29 Use of compositions comprising various tumor-associated antigens as anti-cancer vaccines

Publications (2)

Publication Number Publication Date
JP2008526760A true JP2008526760A (ja) 2008-07-24
JP2008526760A5 JP2008526760A5 (https=) 2009-02-26

Family

ID=36499393

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007549637A Pending JP2008526760A (ja) 2004-12-29 2005-12-29 種々の腫瘍関連抗原を含む組成物の抗癌ワクチンとしての使用

Country Status (8)

Country Link
US (1) US20060159694A1 (https=)
EP (1) EP1833506B1 (https=)
JP (1) JP2008526760A (https=)
AU (1) AU2005321898B2 (https=)
CA (1) CA2592968A1 (https=)
IL (1) IL184277A (https=)
PL (1) PL1833506T3 (https=)
WO (1) WO2006071983A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013513659A (ja) * 2009-12-15 2013-04-22 セラヴァック ファーマスウティカルズ エイ ビー 腫瘍治療における有効なツールとしての腫瘍血管をターゲティングする新規なワクチン
KR101807162B1 (ko) * 2011-04-21 2017-12-11 주식회사 보령바이젠셀 폴로-유사 키나아제 1의 종양항원 단백질 또는 유전자

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6977074B2 (en) 1997-07-10 2005-12-20 Mannkind Corporation Method of inducing a CTL response
US7178491B2 (en) * 2003-06-05 2007-02-20 Caterpillar Inc Control system and method for engine valve actuator
US8202841B2 (en) * 2004-06-17 2012-06-19 Mannkind Corporation SSX-2 peptide analogs
US20060165711A1 (en) * 2004-12-29 2006-07-27 Bot Adrian I Methods to elicit, enhance and sustain immune responses against MHC class I-restricted epitopes, for prophylactic or therapeutic purposes
EP1838342A2 (en) * 2004-12-29 2007-10-03 Mannkind Corporation Methods to bypass cd+4 cells in the induction of an immune response
EP1838338A2 (en) * 2004-12-29 2007-10-03 Mannkind Corporation Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
CN101355965A (zh) 2005-06-08 2009-01-28 达纳-法伯癌症研究院 通过抑制程序性细胞死亡1(pd-1)途经治疗持续性感染和癌症的方法及组合物
CN101687020A (zh) * 2005-06-17 2010-03-31 曼康公司 用于癌症的多价引发-和-增强免疫治疗剂
NZ564359A (en) * 2005-06-17 2011-09-30 Mannkind Corp Analogs of pepetides corresponding to class I MHC-restricted T cell epitopes
MX2007015933A (es) 2005-06-17 2008-04-21 Mannkind Corp Metodos y composiciones para generar respuestas inmunes multivalentes contra espitopes dominantes y subdominantes, expresados en celulas cancerigenas y estromas tumorales.
US7700567B2 (en) 2005-09-29 2010-04-20 Supergen, Inc. Oligonucleotide analogues incorporating 5-aza-cytosine therein
WO2008008541A2 (en) * 2006-07-14 2008-01-17 Mannkind Corporation Methods to elicit, enhance and sustain immune responses against mhc class-i restricted epitopes, for prophylactic or therapeutic purposes
EP2129389B1 (en) 2007-02-15 2014-10-08 MannKind Corporation A method for enhancing t cell response
WO2009127046A1 (en) * 2008-04-14 2009-10-22 Proscan Rx Pharma Inc. Prostate specific membrane antigen antibodies and antigen binding fragments
AU2010310468A1 (en) 2009-10-23 2012-05-24 Mannkind Corporation Cancer immunotherapy and method of treatment
CN103403187A (zh) * 2011-01-18 2013-11-20 艾沃锐斯特基因有限公司 结肠直肠癌复发的预后特征
KR20120116518A (ko) * 2011-04-11 2012-10-23 한국생명공학연구원 폐암 조기 진단용 XAGE-1a 마커 및 이의 용도
EP2750768B1 (en) 2011-08-30 2018-10-03 Astex Pharmaceuticals, Inc. Decitabine derivative formulations
SI2961388T1 (sl) 2013-03-01 2019-10-30 Astex Pharmaceuticals Inc Kombinacije zdravil
AU2016287585B2 (en) 2015-07-02 2020-12-17 Otsuka Pharmaceutical Co., Ltd. Lyophilized pharmaceutical compositions
KR20200035438A (ko) 2017-08-03 2020-04-03 오쓰까 세이야꾸 가부시키가이샤 약물 화합물 및 이의 정제 방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001085932A2 (en) * 2000-05-10 2001-11-15 Aventis Pasteur Limited Immunogenic polypeptides encoded by mage minigenes and uses thereof
JP2003512335A (ja) * 1999-10-18 2003-04-02 セント ビンセンツ ホスピタル アンド メディカル センター オブ ニューヨーク メラノーマワクチン並びにその製造方法及び使用方法
WO2003034903A2 (en) * 2001-10-23 2003-05-01 Psma Development Company, L.L.C. Psma antibodies and protein multimers
JP2003535824A (ja) * 2000-04-28 2003-12-02 シーティーエル イムノセラピーズ コーポレーション 抗原提示細胞におけるエピトープ同調
US20030228634A1 (en) * 2001-11-07 2003-12-11 Simard John J.L. Expression vectors encoding epitopes of target-associated antigens and methods for their design

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US568388A (en) 1896-09-29 Antirefilling bottle
US5804381A (en) 1996-10-03 1998-09-08 Cornell Research Foundation Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5342774A (en) 1991-05-23 1994-08-30 Ludwig Institute For Cancer Research Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
ES2276390T3 (es) 1992-11-05 2007-06-16 Sloan-Kettering Institute For Cancer Research Antigeno de membrana especifico de la prostata.
US5747271A (en) * 1992-12-22 1998-05-05 Ludwig Institute For Cancer Research Method for identifying individuals suffering from a cellular abnormality some of whose abnormal cells present complexes of HLA-A2/tyrosinase derived peptides, and methods for treating said individuals
US5620886A (en) * 1993-03-18 1997-04-15 Ludwig Institute For Cancer Research Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2
US5571711A (en) * 1993-06-17 1996-11-05 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for BAGE tumor rejection antigen precursors
US5648226A (en) * 1993-07-22 1997-07-15 Ludwig Institute For Cancer Research Isolated peptides derived from tumor rejection antigens, and their use
US5858689A (en) * 1993-07-22 1999-01-12 Ludwig Institute For Cancer Research Isolated peptides derived from the gage tumor rejection antigen precursor and uses thereof
US6013481A (en) * 1993-07-22 2000-01-11 Ludwig Institute For Cancer Research Isolated, nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof
US5610013A (en) 1993-07-22 1997-03-11 Ludwig Institute For Cancer Research Method for diagnosing a disorder by determining expression of gage tumor rejection antigen precursors
US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5935818A (en) * 1995-02-24 1999-08-10 Sloan-Kettering Institute For Cancer Research Isolated nucleic acid molecule encoding alternatively spliced prostate-specific membrane antigen and uses thereof
US5874560A (en) 1994-04-22 1999-02-23 The United States Of America As Represented By The Department Of Health And Human Services Melanoma antigens and their use in diagnostic and therapeutic methods
US5830753A (en) 1994-09-30 1998-11-03 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof.
US6025191A (en) * 1995-06-07 2000-02-15 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode a melanoma specific antigen and uses thereof
US5856136A (en) 1996-07-03 1999-01-05 Incyte Pharmaceuticals, Inc. Human stem cell antigens
EP2286831A1 (en) 1997-07-10 2011-02-23 Mannkind Corporation A method of inducing a CTL response
US6994851B1 (en) 1997-07-10 2006-02-07 Mannkind Corporation Method of inducing a CTL response
US6977074B2 (en) 1997-07-10 2005-12-20 Mannkind Corporation Method of inducing a CTL response
US6709844B1 (en) * 2000-11-16 2004-03-23 Mannkind Corporation Avoidance of undesirable replication intermediates in plasmid propagation
US20030138808A1 (en) 1998-02-19 2003-07-24 Simard John J.L. Expression vectors encoding epitopes of target-associated antigens
GB9804121D0 (en) 1998-02-26 1998-04-22 Cancer Res Campaign Tech Anti-angiogenic vaccines: materials and methods relating thereto
EP1179541B1 (en) * 1999-04-28 2004-06-16 Board Of Regents, The University Of Texas System Compositions and methods for cancer treatment by selectively inhibiting VEGF
US6861234B1 (en) 2000-04-28 2005-03-01 Mannkind Corporation Method of epitope discovery
US20030215425A1 (en) 2001-12-07 2003-11-20 Simard John J. L. Epitope synchronization in antigen presenting cells
JP2005505242A (ja) * 2001-03-07 2005-02-24 マンカインド コーポレイション 癌用抗新生血管系調製物
EP1595548A3 (en) * 2001-03-07 2006-02-22 Mannkind Corporation Anti-neovasculature preparations for treating cancer
WO2003008537A2 (en) * 2001-04-06 2003-01-30 Mannkind Corporation Epitope sequences
WO2004022709A2 (en) 2002-09-06 2004-03-18 Mannkind Corporation Epitope sequences
AU2004249254B2 (en) * 2003-06-17 2010-07-08 Mannkind Corporation Combinations of tumor-associated antigens for the treatment of various types of cancers
DE602004028468D1 (de) 2003-06-17 2010-09-16 Mannkind Corp Haltung von immunantworten gegen mhc-klasse-i-beschränkte epitope, für prophylaktische oder therapeutische zwecke
EP1773402A2 (en) 2004-06-17 2007-04-18 Mannkind Corporation Improved efficacy of immunotherapy by integrating diagnostic with therapeutic methods
US8202841B2 (en) * 2004-06-17 2012-06-19 Mannkind Corporation SSX-2 peptide analogs
JP2008503498A (ja) * 2004-06-17 2008-02-07 マンカインド コーポレイション 癌の診断及び免疫療法における腫瘍関連抗原プロファイル
US20060159689A1 (en) * 2004-06-17 2006-07-20 Chih-Sheng Chiang Combinations of tumor-associated antigens in diagnostics for various types of cancers
US20060008468A1 (en) * 2004-06-17 2006-01-12 Chih-Sheng Chiang Combinations of tumor-associated antigens in diagnostics for various types of cancers
US20080206270A1 (en) * 2004-07-08 2008-08-28 Minev Boris R Enhancing Class I Antigen Presentation With Synthetic Sequences
EP1838338A2 (en) * 2004-12-29 2007-10-03 Mannkind Corporation Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
US20060165711A1 (en) * 2004-12-29 2006-07-27 Bot Adrian I Methods to elicit, enhance and sustain immune responses against MHC class I-restricted epitopes, for prophylactic or therapeutic purposes
NZ564359A (en) * 2005-06-17 2011-09-30 Mannkind Corp Analogs of pepetides corresponding to class I MHC-restricted T cell epitopes
MX2007015933A (es) * 2005-06-17 2008-04-21 Mannkind Corp Metodos y composiciones para generar respuestas inmunes multivalentes contra espitopes dominantes y subdominantes, expresados en celulas cancerigenas y estromas tumorales.
CN101687020A (zh) * 2005-06-17 2010-03-31 曼康公司 用于癌症的多价引发-和-增强免疫治疗剂

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003512335A (ja) * 1999-10-18 2003-04-02 セント ビンセンツ ホスピタル アンド メディカル センター オブ ニューヨーク メラノーマワクチン並びにその製造方法及び使用方法
JP2003535824A (ja) * 2000-04-28 2003-12-02 シーティーエル イムノセラピーズ コーポレーション 抗原提示細胞におけるエピトープ同調
WO2001085932A2 (en) * 2000-05-10 2001-11-15 Aventis Pasteur Limited Immunogenic polypeptides encoded by mage minigenes and uses thereof
WO2003034903A2 (en) * 2001-10-23 2003-05-01 Psma Development Company, L.L.C. Psma antibodies and protein multimers
US20030228634A1 (en) * 2001-11-07 2003-12-11 Simard John J.L. Expression vectors encoding epitopes of target-associated antigens and methods for their design
US20040132088A1 (en) * 2001-11-07 2004-07-08 Simard John J.L. Expression vectors encoding epitopes of target-associated antigens and methods for their design

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
JPN6011036730; REYNOLDS,S.R. et al: 'Identification of HLA-A*03, A*11 and B*07-restricted melanoma-associated peptides that are immunogen' J Immunol Methods Vol.244, No.1-2, 2000, p.59-67 *
JPN6011036732; SMITH,S.G. et al: 'Human dendritic cells genetically engineered to express a melanoma polyepitope DNA vaccine induce mu' Clin Cancer Res Vol.7, No.12, 2001, p.4253-61 *
JPN6011036734; CHANG,S.S. et al: 'Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in' Cancer Res Vol.59, No.13, 1999, p.3192-8 *
JPN6011036736; CHANG,S.S. et al: 'Prostate-specific membrane antigen is produced in tumor-associated neovasculature' Clin Cancer Res Vol.5, No.10, 1999, p.2674-81 *
JPN6011036740; KESSLER,J.H. et al: 'Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the wide' J Exp Med Vol.193, No.1, 2001, p.73-88 *
JPN6011036742; MOINGEON,P.: 'Cancer vaccines' Vaccine Vol.19, No.11-12, 2001, p.1305-26 *
JPN6011036746; MATSUSHITA,M. et al: 'Preferentially expressed antigen of melanoma (PRAME) in the development of diagnostic and therapeuti' Leuk Lymphoma Vol.44, No.3, 2003, p.439-44 *
JPN6012031857; CHANG,S.S.: 'Monoclonal antibodies and prostate-specific membrane antigen' Curr Opin Investig Drugs Vol.5, No.6, 2004, p.611-5 *
JPN6012031859; 池田英之ら: 'PRAME蛋白を標的とした抗白血病免疫療法の可能性' 今日の移植 Vol.15, No.1, 2002, 27-32 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013513659A (ja) * 2009-12-15 2013-04-22 セラヴァック ファーマスウティカルズ エイ ビー 腫瘍治療における有効なツールとしての腫瘍血管をターゲティングする新規なワクチン
KR101807162B1 (ko) * 2011-04-21 2017-12-11 주식회사 보령바이젠셀 폴로-유사 키나아제 1의 종양항원 단백질 또는 유전자

Also Published As

Publication number Publication date
EP1833506B1 (en) 2015-08-26
WO2006071983A9 (en) 2007-04-19
AU2005321898A1 (en) 2006-07-06
IL184277A0 (en) 2007-10-31
WO2006071983A3 (en) 2007-03-08
EP1833506A2 (en) 2007-09-19
IL184277A (en) 2013-02-28
CA2592968A1 (en) 2006-07-06
AU2005321898B2 (en) 2012-07-19
WO2006071983A2 (en) 2006-07-06
US20060159694A1 (en) 2006-07-20
PL1833506T3 (pl) 2016-01-29

Similar Documents

Publication Publication Date Title
JP5283335B2 (ja) 各種癌の治療を目的とした腫瘍関連抗原の組合せ
JP2008526760A (ja) 種々の腫瘍関連抗原を含む組成物の抗癌ワクチンとしての使用
JP2008546687A (ja) 種々の型の癌の診断における腫瘍関連抗原の組合せ
ES2351995T3 (es) Perfiles de antígenos asociados a tumores en el diagnóstico de cáncer e inmunoterapia.
US20110274723A1 (en) Cancer immunotherapy and method of treatment
Mukherjee et al. Mucin 1-specific immunotherapy in a mouse model of spontaneous breast cancer
US20060159689A1 (en) Combinations of tumor-associated antigens in diagnostics for various types of cancers
JP2003535824A (ja) 抗原提示細胞におけるエピトープ同調
JP2001509490A (ja) Ctl応答を誘導する方法
JP2021038225A (ja) ネコ用がんワクチン
Kelly et al. Targeting the immune system in non–small-cell lung cancer: bridging the gap between promising concept and therapeutic reality
AU2007272785A1 (en) Methods to elicit, enhance and sustain immune responses against MHC class-I restricted epitopes, for prophylactic or therapeutic purposes
Lollini et al. Preclinical vaccines against mammary carcinoma
Stan et al. DNA vaccines against cancer
Renner et al. Clinical approaches to vaccination in oncology
Hersey et al. Melanoma vaccines
Dai et al. Development of an Escherichia coli expressing listeriolysin-O vaccine against Wilms tumor gene 1-expressing tumors
Bavafa et al. Nanoliposome-encapsulated MAGE peptides: A promising melanoma vaccine to activate human dendritic cells
Slovin Prostate-specific membrane antigen vaccines: naked DNA and protein approaches
Masucci Will modern cancer vaccines reach clinical practice?

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090105

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090105

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110719

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20111018

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20111025

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120118

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120626

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20121120