JP2008525468A - ポストコンディショニング臓器保護作用を増強する治療補助薬 - Google Patents

ポストコンディショニング臓器保護作用を増強する治療補助薬 Download PDF

Info

Publication number
JP2008525468A
JP2008525468A JP2007548436A JP2007548436A JP2008525468A JP 2008525468 A JP2008525468 A JP 2008525468A JP 2007548436 A JP2007548436 A JP 2007548436A JP 2007548436 A JP2007548436 A JP 2007548436A JP 2008525468 A JP2008525468 A JP 2008525468A
Authority
JP
Japan
Prior art keywords
tissue
inhibitor
organ
perfusion
reperfusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007548436A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008525468A5 (enExample
Inventor
ジェイコブ−ビンテン・ジョハンセン
チ−キン・チャオ
Original Assignee
エモリー・ユニバーシティ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エモリー・ユニバーシティ filed Critical エモリー・ユニバーシティ
Publication of JP2008525468A publication Critical patent/JP2008525468A/ja
Publication of JP2008525468A5 publication Critical patent/JP2008525468A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
  • Materials For Medical Uses (AREA)
JP2007548436A 2004-12-22 2005-12-20 ポストコンディショニング臓器保護作用を増強する治療補助薬 Withdrawn JP2008525468A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63846104P 2004-12-22 2004-12-22
PCT/US2005/046417 WO2006069170A2 (en) 2004-12-22 2005-12-20 Therapeutic adjuncts to enhance the organ protective effects of postconditioning

Publications (2)

Publication Number Publication Date
JP2008525468A true JP2008525468A (ja) 2008-07-17
JP2008525468A5 JP2008525468A5 (enExample) 2009-01-29

Family

ID=36602296

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007548436A Withdrawn JP2008525468A (ja) 2004-12-22 2005-12-20 ポストコンディショニング臓器保護作用を増強する治療補助薬

Country Status (6)

Country Link
US (1) US20080097385A1 (enExample)
EP (1) EP1827298A4 (enExample)
JP (1) JP2008525468A (enExample)
AU (1) AU2005319144A1 (enExample)
CA (1) CA2592142A1 (enExample)
WO (1) WO2006069170A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012210361A (ja) * 2011-03-31 2012-11-01 Terumo Corp 肢部圧迫装置
JP2013510832A (ja) * 2009-11-16 2013-03-28 アンスティテュ ナシオナル ドゥ ラ ルシェルシュ アグロノミック A型インフルエンザウイルス感染症の治療または予防用のpar−1アンタゴニスト
JP2013523240A (ja) * 2010-03-31 2013-06-17 ザ・ホスピタル・フォー・シック・チルドレン 心筋梗塞後の結果を改善するための遠隔虚血コンディショニングの使用

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020001797A (ko) 1999-03-23 2002-01-09 제임스 쿡 유니버시티 신체 기관의 정지, 보호 및 보존
ATE411058T1 (de) 2001-10-25 2008-10-15 Univ Emory Katheter für modifizierte perfusion
EP3064242A1 (en) 2003-04-28 2016-09-07 Advanced Circulatory Systems Inc. Ventilator and methods for treating head trauma and low blood circulation
KR101425579B1 (ko) 2006-05-29 2014-08-13 하이버네이션 테라퓨틱스 리미티드 개선된 조직 유지법
ES2539762T3 (es) 2006-07-25 2015-07-03 Hibernation Therapeutics, A Kf Llc Tratamiento de traumatismos
US7717855B2 (en) 2006-12-06 2010-05-18 The Hospital For Sick Children System for performing remote ischemic preconditioning
CA2717162A1 (en) 2007-03-02 2008-09-12 Hibernation Therapeutics Limited Transplants
US20110046039A1 (en) * 2007-03-09 2011-02-24 George Mason Intellectual Properties Inc. Post-exposure prophylaxis and treatment of infections
US9352111B2 (en) 2007-04-19 2016-05-31 Advanced Circulatory Systems, Inc. Systems and methods to increase survival with favorable neurological function after cardiac arrest
US8151790B2 (en) 2007-04-19 2012-04-10 Advanced Circulatory Systems, Inc. Volume exchanger valve system and method to increase circulation during CPR
CA2731398A1 (en) * 2007-07-25 2009-01-29 Hibernation Therapeutics Limited Improved organ protection, preservation and recovery
US20110190727A1 (en) * 2010-02-02 2011-08-04 Boston Scientific Scimed, Inc. Intervascular catheter, system and method
US9724266B2 (en) 2010-02-12 2017-08-08 Zoll Medical Corporation Enhanced guided active compression decompression cardiopulmonary resuscitation systems and methods
US12016820B2 (en) 2010-02-12 2024-06-25 Zoll Medical Corporation Enhanced guided active compression decompression cardiopulmonary resuscitation systems and methods
US20120330199A1 (en) * 2010-07-02 2012-12-27 ResQSystems, Inc. Methods and systems for reperfusion injury protection after cardiac arrest
KR20130040878A (ko) 2010-04-08 2013-04-24 더 호스피탈 포 식 칠드런 외상성 손상을 위한 원격 허혈 처치의 사용
EP2563446A1 (en) 2010-04-30 2013-03-06 Abbott Cardiovascular Systems Inc. Improved balloon catheter exhibiting rapid inflation and deflation
US8480650B2 (en) 2010-04-30 2013-07-09 Abbott Cardiovascular Systems Inc. Method for increased uptake of beneficial agent and ejection fraction by postconditioning procedures
US8821438B2 (en) 2010-04-30 2014-09-02 Abbott Cardiovascular Systems, Inc. Catheter system having a fluid circuit
US8708996B2 (en) 2010-04-30 2014-04-29 Abbott Cardiovascular Systems, Inc. Methods and device for synergistic mitigation of reperfusion injury after an ischemic event
US8540669B2 (en) 2010-04-30 2013-09-24 Abbott Cardiovascular Systems Inc. Catheter system providing step reduction for postconditioning
US9168361B2 (en) 2010-04-30 2015-10-27 Abbott Cardiovascular Systems Inc. Balloon catheter exhibiting rapid inflation and deflation
US9533124B2 (en) 2011-04-14 2017-01-03 Abbott Cardiovascular Systems Inc. Reperfusion injury devices
JP2014533697A (ja) * 2011-11-18 2014-12-15 アポテックス テクノロジーズ インコーポレイテッドApotex Technologies Inc. デフェリプロンを用いた処置方法
WO2013096495A1 (en) 2011-12-19 2013-06-27 ResQSystems, Inc. Systems and methods for therapeutic intrathoracic pressure regulation
WO2014199239A2 (en) 2013-03-15 2014-12-18 The Hospital For Sick Children Methods relating to the use of remote ischemic conditioning
US10098779B2 (en) 2013-03-15 2018-10-16 The Hospital For Sick Children Treatment of erectile dysfunction using remote ischemic conditioning
WO2014167423A2 (en) 2013-03-15 2014-10-16 The Hospital For Sick Children Methods for modulating autophagy using remote ischemic conditioning
US9811634B2 (en) 2013-04-25 2017-11-07 Zoll Medical Corporation Systems and methods to predict the chances of neurologically intact survival while performing CPR
US20140358047A1 (en) 2013-05-30 2014-12-04 ResQSystems, Inc. End-tidal carbon dioxide and amplitude spectral area as non-invasive markers of coronary perfusion pressure and arterial pressure
BR112016000804A2 (pt) 2013-07-17 2017-08-22 Hibernation Therapeuitics A Kf Llc Método para tratar hemorragia, choque e lesão cerebral
US10265495B2 (en) 2013-11-22 2019-04-23 Zoll Medical Corporation Pressure actuated valve systems and methods
US10092591B2 (en) * 2014-02-27 2018-10-09 University Of Alaska Fairbanks Methods and compositions for the treatment of ischemic injury to tissue using therapeutic hypothermia
KR102667251B1 (ko) * 2018-01-10 2024-05-21 터프츠 메디컬 센터, 인크 심근 경색 치료시 좌심실 언로딩 시스템 및 방법

Family Cites Families (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4781677A (en) * 1985-07-17 1988-11-01 Wilcox Gilbert M Method of treatment utilizing a double balloon nasobiliary occlusion catheter
US4691708A (en) * 1986-03-10 1987-09-08 Cordis Corporation Optical pressure sensor for measuring blood pressure
US4769010A (en) * 1987-02-11 1988-09-06 Strato Medical Corporation Catheter needle assembly with adjustable height support
US4901731A (en) * 1988-04-27 1990-02-20 Millar Instruments, Inc. Single sensor pressure differential device
US4929236A (en) * 1988-05-26 1990-05-29 Shiley Infusaid, Inc. Snap-lock fitting catheter for an implantable device
US5011469A (en) * 1988-08-29 1991-04-30 Shiley, Inc. Peripheral cardiopulmonary bypass and coronary reperfusion system
US4943277A (en) * 1989-03-24 1990-07-24 Bolling Steven F Retrograde coronary sinus cardioplegia cannula and method for using same in heart surgery
US5129891A (en) * 1989-05-19 1992-07-14 Strato Medical Corporation Catheter attachment device
DE4003425A1 (de) * 1990-02-06 1991-08-08 Beyersdorf Friedhelm Dr Med Reperfusionsvorrichtung
US5108369A (en) * 1990-03-15 1992-04-28 Diagnostic Devices Group, Limited Dual-diameter multifunction catheter
US5190520A (en) * 1990-10-10 1993-03-02 Strato Medical Corporation Reinforced multiple lumen catheter
US5178612A (en) * 1990-10-10 1993-01-12 Strato Medical Corporation Compressible split cylinder bayonet locking device for attachment of a catheter to a fluid transfer device
US5156600A (en) * 1990-10-10 1992-10-20 Strato Medical Corporation Bidirectional check valve catheter
US6309639B1 (en) * 1991-02-05 2001-10-30 The Board Of Regents Of The University Of Oklahoma Method for inhibiting an inflammatory response using antibodies to P-selectin glycoprotein ligand
US5112301A (en) * 1991-06-19 1992-05-12 Strato Medical Corporation Bidirectional check valve catheter
US5584803A (en) * 1991-07-16 1996-12-17 Heartport, Inc. System for cardiac procedures
US5879499A (en) * 1996-06-17 1999-03-09 Heartport, Inc. Method of manufacture of a multi-lumen catheter
US5769812A (en) * 1991-07-16 1998-06-23 Heartport, Inc. System for cardiac procedures
US5195942A (en) * 1991-08-12 1993-03-23 Institute Of Critical Care Medicine Cardiac arrest treatment
US6224619B1 (en) * 1991-12-17 2001-05-01 Heartport, Inc. Blood vessel occlusion trocar having size and shape varying insertion body
US5224938A (en) * 1992-03-18 1993-07-06 Strato Medical Corporation Valved catheter
US6325067B1 (en) * 1992-12-03 2001-12-04 Wesley D. Sterman Methods and systems for performing thoracoscopic coronary bypass and other procedures
US6283127B1 (en) * 1992-12-03 2001-09-04 Wesley D. Sterman Devices and methods for intracardiac procedures
US5573502A (en) * 1993-05-26 1996-11-12 Quest Medical, Inc. Display panel and controls for blood mixture delivery system
CN1102851C (zh) * 1993-06-04 2003-03-12 生物时间公司 类血浆溶液
US5759170A (en) * 1993-11-30 1998-06-02 Heartport, Inc. Method for intraluminally inducing cardioplegic arrest and catheter for use therein
US5478309A (en) * 1994-05-27 1995-12-26 William P. Sweezer, Jr. Catheter system and method for providing cardiopulmonary bypass pump support during heart surgery
US5695457A (en) * 1994-07-28 1997-12-09 Heartport, Inc. Cardioplegia catheter system
US6607698B1 (en) * 1997-08-15 2003-08-19 Therox, Inc. Method for generalized extracorporeal support
US5868776A (en) * 1996-09-03 1999-02-09 Ideas For Medicine, Inc. Overlay dual balloon catheter and method for use thereof
US5993382A (en) * 1996-11-27 1999-11-30 Horizon Medical Products, Inc. Lighted catheter device and method for use and manufacture thereof
DE19702402A1 (de) * 1997-01-24 1998-07-30 Beyersdorf Friedhelm Univ Prof Verfahren und Reperfusionsvorrichtung
US5957879A (en) * 1997-01-24 1999-09-28 Heartport, Inc. Methods and devices for maintaining cardiopulmonary bypass and arresting a patient's heart
US5755687A (en) * 1997-04-01 1998-05-26 Heartport, Inc. Methods and devices for occluding a patient's ascending aorta
DE19741635A1 (de) * 1997-09-22 1999-03-25 Hoechst Marion Roussel De Gmbh Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament
US6991645B2 (en) * 1998-01-23 2006-01-31 Innercool Therapies, Inc. Patient temperature regulation method and apparatus
US6295990B1 (en) * 1998-02-03 2001-10-02 Salient Interventional Systems, Inc. Methods and systems for treating ischemia
US6736790B2 (en) * 1998-02-25 2004-05-18 Denise R. Barbut Method and system for selective or isolated integrate cerebral perfusion and cooling
US6235714B1 (en) * 1998-03-23 2001-05-22 Sudhir Paul Methods for identifying inducers and inhibitors of proteolytic antibodies, compositions and their uses
US6602467B1 (en) * 1998-07-24 2003-08-05 Therox, Inc. Apparatus and method for blood oxygenation
US7914564B2 (en) * 1999-02-09 2011-03-29 Innercool Therapies, Inc. System and method for patient temperature control employing temperature projection algorithm
US6830581B2 (en) * 1999-02-09 2004-12-14 Innercool Therspies, Inc. Method and device for patient temperature control employing optimized rewarming
US6315768B1 (en) * 1999-06-08 2001-11-13 Richard K. Wallace Perfusion procedure and apparatus for preventing necrosis following failed balloon angioplasty
US6576191B1 (en) * 1999-09-30 2003-06-10 Therox, Inc. Apparatus for blood oxygenation
US6387324B1 (en) * 1999-09-30 2002-05-14 Therox, Inc. Apparatus and method for blood oxygenation
AU4710401A (en) * 1999-12-02 2001-06-18 University Of South Florida Method and composition for treatment of ischemic neuronal reperfusion injury
US20030040531A1 (en) * 2000-01-25 2003-02-27 Kazuyuki Fujishima Remedies for reperfusion injury containing integrin alphanubeta 3 antagonist
US6534651B2 (en) * 2000-04-06 2003-03-18 Inotek Pharmaceuticals Corp. 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof
US6900178B2 (en) * 2000-09-12 2005-05-31 University Of Kentucky Research Foundation Protection against ischemia and reperfusion injury
US6645938B2 (en) * 2000-10-10 2003-11-11 Zymogenetics, Inc. Protection against ischemia and reperfusion injury
US6585675B1 (en) * 2000-11-02 2003-07-01 Chf Solutions, Inc. Method and apparatus for blood withdrawal and infusion using a pressure controller
US6423705B1 (en) * 2001-01-25 2002-07-23 Pfizer Inc. Combination therapy
US20030216582A1 (en) * 2001-02-08 2003-11-20 Nicholas Nikolaides 2-carboxamide-benzimidazoles useful in the treatment and prevention of ischemic reperfusion injury
WO2002092124A1 (en) * 2001-05-11 2002-11-21 Wyeth Methods for diagnosing and treating ischemia and reperfusion injury and compositions thereof
US20040131607A1 (en) * 2001-06-08 2004-07-08 Carroll Michael C. Methods and compositions for inhibiting immunoglobulin-mediated reperfusion injury
US6827701B2 (en) * 2001-07-17 2004-12-07 Kerberos Proximal Solutions Fluid exchange system for controlled and localized irrigation and aspiration
JP2003096308A (ja) * 2001-09-25 2003-04-03 Asahi Glass Co Ltd 撥水撥油性組成物およびその造形品
WO2003059266A2 (en) * 2001-12-21 2003-07-24 Emory University Post-conditioning for the reduction of ischemic-reperfusion injury in the heart and other organs
AU2002352519A1 (en) * 2001-11-09 2003-05-26 The General Hospital Corporation Methods for treating ischemic reperfusion injury using ikb kinase-beta inhibitors
US6544950B1 (en) * 2001-12-06 2003-04-08 University Of Kentucky Research Foundation Seventeen amino acid peptide (Peptide P) for treating ischemia and reperfusion injury
US6844361B2 (en) * 2002-02-04 2005-01-18 Aventis Pharma Deutschland Gmbh Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor
US20030220383A1 (en) * 2002-02-14 2003-11-27 Aventis Pharma Deutschland Gmbh Use of inhibitors of the sodium-dependent chloride/bicarbonate exchanger for the treatment of thrombotic and inflammatory disorders
AU2003236509A1 (en) * 2002-06-12 2003-12-31 Biogen Idec Ma Inc. Method of treating ischemia reperfusion injury using adenosine receptor antagonists
EP2011489A3 (en) * 2002-07-09 2009-04-22 Roberta Gottlieb Method to inhibit ischemia and reperfusion injury
US20050143475A1 (en) * 2002-07-29 2005-06-30 Lockwood Samuel F. Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury
BRPI0313155B8 (pt) * 2002-07-29 2021-05-25 Cardax Pharmaceuticals Inc composto químico derivado ou análogo de carotenóide, composição farmacêutica, e, uso do composto
US20040111079A1 (en) * 2002-12-03 2004-06-10 Richard Hayes Targeted sanguinous drug solution delivery to a targeted organ
US7004961B2 (en) * 2003-01-09 2006-02-28 Edward Wong Medical device and method for temperature control and treatment of the brain and spinal cord
WO2004075837A2 (en) * 2003-02-21 2004-09-10 Tanox, Inc. Methods for preventing and treating tissue damage associated with ischemia-reperfusion injury
PL1608400T3 (pl) * 2003-03-28 2010-11-30 Faron Pharmaceuticals Oy Podwyższanie poziomu adenozyny przez indukowaną przez cytokiny ekspresję CD73
US20060051407A1 (en) * 2003-06-27 2006-03-09 Yoram Richter Method of treating ischemia-reperfusion injury
US20050187221A1 (en) * 2003-09-08 2005-08-25 Japan Tobacco Inc. Method of treating ischemia reperfusion injury
US20060029589A1 (en) * 2004-06-01 2006-02-09 Hartmut Weiler Induction of heterozygous FV Leiden carrier status to reduce mortality in sepsis and to prevent organ damage caused by inflammation and/or ischemia-reperfusion injury
US7304073B2 (en) * 2004-08-20 2007-12-04 Wyeth Method of treating myocardial ischemia-reperfusion injury using NF-kB inhibitors
US20060136023A1 (en) * 2004-08-26 2006-06-22 Dobak John D Iii Method and apparatus for patient temperature control employing administration of anti-shivering agents
US7332159B2 (en) * 2004-09-30 2008-02-19 Board Of Regents Of The University Of Nebraska Method and composition for inhibiting reperfusion injury in the brain

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013510832A (ja) * 2009-11-16 2013-03-28 アンスティテュ ナシオナル ドゥ ラ ルシェルシュ アグロノミック A型インフルエンザウイルス感染症の治療または予防用のpar−1アンタゴニスト
JP2013523240A (ja) * 2010-03-31 2013-06-17 ザ・ホスピタル・フォー・シック・チルドレン 心筋梗塞後の結果を改善するための遠隔虚血コンディショニングの使用
JP2016052600A (ja) * 2010-03-31 2016-04-14 ザ・ホスピタル・フォー・シック・チルドレンThe Hospital For Sick Children 心筋梗塞後の結果を改善するための遠隔虚血コンディショニングの使用
JP2012210361A (ja) * 2011-03-31 2012-11-01 Terumo Corp 肢部圧迫装置

Also Published As

Publication number Publication date
EP1827298A4 (en) 2011-09-28
EP1827298A2 (en) 2007-09-05
US20080097385A1 (en) 2008-04-24
WO2006069170A2 (en) 2006-06-29
WO2006069170A3 (en) 2007-01-04
CA2592142A1 (en) 2006-06-29
AU2005319144A1 (en) 2006-06-29

Similar Documents

Publication Publication Date Title
JP2008525468A (ja) ポストコンディショニング臓器保護作用を増強する治療補助薬
JP4514838B2 (ja) 過増殖性の血管疾患を予防するための医薬組成物
US5453436A (en) Treatment of athereosclerosis using, carbazolyl-(4)-oxypropanolamine compounds
JP2009172394A (ja) 心臓および他の器官における虚血−再灌流傷害の軽減のための事後調節
EP4114466B1 (en) Treatment of pain and vasoconstriction
EP1258250B1 (en) Nerve protective drugs
ES2349244T3 (es) Procedimientos para reducir la angiogénesis.
Colson et al. Mechanisms of renal hemodynamic impairment during infrarenal aortic cross-clamping
Velasco et al. Myocardial reperfusion injury in the canine model after 40 minutes of ischemia: effect of intracoronary adenosine
Scriabine et al. Nimodipine: Pharmacological and clinical results in cerebral ischemia
Rahn How should we treat a hypertensive emergency?
US20220273754A1 (en) Ss-31 for the prevention and/or treatment of aneurysm
EP1190714A2 (en) Method for the treatment of thromboembolic disorders in patients with aspirin resistance
Kenyon New Drug Approvals: Clevidipine: An Ultra Short-Acting Calcium Channel Antagonist for Acute Hypertension
KR20190072011A (ko) 나토키나제와 항염증제를 유효성분으로 포함하는 혈소판 응집 억제용 또는 혈전용해용 의약 조성물
Kawabata et al. Experience with calcium antagonists nitrendipine, diltiazem, and verapamil and β2‐agonist salbutamol in salvaging ischemic skin flaps in rabbits
EP3085371A1 (en) Parthenolide and its derivatives for use in the treatment of axonal damage
US20240252457A1 (en) Treatment or Prevention of Ischaemia Reperfusion Injury
WO2008062040A1 (en) Anticonvulsive pharmaceutical compositions
WO2014152864A1 (en) Treatment for chemotherapy-induced cognitive impairment
HUT76834A (en) Use of (s)-adenosyl-l-methionine (same) and its physiologically compatible salts for preparing pharmaceutical compositions for treating reperfusion damage triggered by temporary focal ischemia
EP1582213A1 (en) Use of adenosine for treating surgery related ischemia
JP2000229854A (ja) 虚血性神経細胞死治療・予防用脳室内投与剤、血管性痴呆症治療・予防用脳室内投与剤、並びに脳内手術時投与剤
JPH0826994A (ja) 脳血管攣縮治療剤
JPWO2006041061A1 (ja) 脳梗塞抑制剤

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20081205

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20081205

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20110817