AU2005319144A1 - Therapeutic adjuncts to enhance the organ protective effects of postconditioning - Google Patents

Therapeutic adjuncts to enhance the organ protective effects of postconditioning Download PDF

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Publication number
AU2005319144A1
AU2005319144A1 AU2005319144A AU2005319144A AU2005319144A1 AU 2005319144 A1 AU2005319144 A1 AU 2005319144A1 AU 2005319144 A AU2005319144 A AU 2005319144A AU 2005319144 A AU2005319144 A AU 2005319144A AU 2005319144 A1 AU2005319144 A1 AU 2005319144A1
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AU
Australia
Prior art keywords
tissue
organ
inhibitors
heart
perfusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2005319144A
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English (en)
Inventor
Jakob-Vinten Johansen
Zhi-Qing Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emory University
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Emory University
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Filing date
Publication date
Application filed by Emory University filed Critical Emory University
Publication of AU2005319144A1 publication Critical patent/AU2005319144A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
  • Materials For Medical Uses (AREA)
AU2005319144A 2004-12-22 2005-12-20 Therapeutic adjuncts to enhance the organ protective effects of postconditioning Abandoned AU2005319144A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63846104P 2004-12-22 2004-12-22
US60/638,461 2004-12-22
PCT/US2005/046417 WO2006069170A2 (en) 2004-12-22 2005-12-20 Therapeutic adjuncts to enhance the organ protective effects of postconditioning

Publications (1)

Publication Number Publication Date
AU2005319144A1 true AU2005319144A1 (en) 2006-06-29

Family

ID=36602296

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005319144A Abandoned AU2005319144A1 (en) 2004-12-22 2005-12-20 Therapeutic adjuncts to enhance the organ protective effects of postconditioning

Country Status (6)

Country Link
US (1) US20080097385A1 (enExample)
EP (1) EP1827298A4 (enExample)
JP (1) JP2008525468A (enExample)
AU (1) AU2005319144A1 (enExample)
CA (1) CA2592142A1 (enExample)
WO (1) WO2006069170A2 (enExample)

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Also Published As

Publication number Publication date
EP1827298A4 (en) 2011-09-28
EP1827298A2 (en) 2007-09-05
US20080097385A1 (en) 2008-04-24
WO2006069170A2 (en) 2006-06-29
JP2008525468A (ja) 2008-07-17
WO2006069170A3 (en) 2007-01-04
CA2592142A1 (en) 2006-06-29

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