JP2008524338A5 - - Google Patents
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- Publication number
- JP2008524338A5 JP2008524338A5 JP2007548599A JP2007548599A JP2008524338A5 JP 2008524338 A5 JP2008524338 A5 JP 2008524338A5 JP 2007548599 A JP2007548599 A JP 2007548599A JP 2007548599 A JP2007548599 A JP 2007548599A JP 2008524338 A5 JP2008524338 A5 JP 2008524338A5
- Authority
- JP
- Japan
- Prior art keywords
- reagent
- hydrogen
- poly
- carbon atoms
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63982304P | 2004-12-21 | 2004-12-21 | |
| US60/639,823 | 2004-12-21 | ||
| US70596805P | 2005-08-04 | 2005-08-04 | |
| US60/705,968 | 2005-08-04 | ||
| PCT/US2005/047337 WO2006069388A2 (en) | 2004-12-21 | 2005-12-21 | Stabilized polymeric thiol reagents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008524338A JP2008524338A (ja) | 2008-07-10 |
| JP2008524338A5 true JP2008524338A5 (enExample) | 2009-01-29 |
| JP5243041B2 JP5243041B2 (ja) | 2013-07-24 |
Family
ID=36440883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007548599A Expired - Lifetime JP5243041B2 (ja) | 2004-12-21 | 2005-12-21 | 安定化ポリマーチオール試薬 |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US7851565B2 (enExample) |
| EP (1) | EP1827501B2 (enExample) |
| JP (1) | JP5243041B2 (enExample) |
| KR (1) | KR101320936B1 (enExample) |
| CN (1) | CN101111267B (enExample) |
| AT (1) | ATE494012T1 (enExample) |
| AU (1) | AU2005318984B2 (enExample) |
| CA (1) | CA2591233C (enExample) |
| DE (1) | DE602005025805D1 (enExample) |
| ES (1) | ES2357089T5 (enExample) |
| MX (1) | MX2007007471A (enExample) |
| WO (1) | WO2006069388A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7947261B2 (en) | 2003-05-23 | 2011-05-24 | Nektar Therapeutics | Conjugates formed from polymer derivatives having particular atom arrangements |
| EP1586334A1 (en) * | 2004-04-15 | 2005-10-19 | TRASTEC scpa | G-CSF conjugates with peg |
| CN101111267B (zh) | 2004-12-21 | 2012-12-05 | 尼克塔治疗公司 | 稳定的聚合物巯基试剂 |
| WO2007019331A2 (en) * | 2005-08-04 | 2007-02-15 | Nektar Therapeutics Al, Corporation | Conjugates of a g-csf moiety and a polymer |
| US8034765B2 (en) | 2005-08-31 | 2011-10-11 | Abraxis Bioscience, Llc | Compositions and methods for preparation of poorly water soluble drugs with increased stability |
| HUE042678T2 (hu) | 2005-08-31 | 2019-07-29 | Abraxis Bioscience Llc | Vízben rosszul oldódó gyógyszerhatóanyagok és antimikrobiális szerek |
| KR100819064B1 (ko) | 2006-12-19 | 2008-04-04 | (재)대구경북과학기술연구원 | 생분자 고정화 링커 |
| EP2014256A1 (en) | 2007-07-12 | 2009-01-14 | Straumann Holding AG | Composite bone repair material |
| WO2009025669A1 (en) * | 2007-08-20 | 2009-02-26 | Enzon Pharmaceuticals, Inc. | Polymeric linkers containing pyridyl disulfide moieties |
| US7847019B2 (en) | 2007-10-15 | 2010-12-07 | California Institute Of Technology | Functionalized polymers using protected thiols |
| US8629104B2 (en) * | 2008-02-18 | 2014-01-14 | Jiangsu Hengrui Medicine Co. Ltd. | G-CSF and water-soluble polymer conjugate |
| JP2011520983A (ja) * | 2008-05-23 | 2011-07-21 | エンゾン ファーマシューティカルズ,インコーポレーテッド | オリゴヌクレオチドの送達のための細胞内遊離可能ジスルフィドリンカーを含有するポリマーシステム |
| JP2013501224A (ja) * | 2009-07-31 | 2013-01-10 | エンドサイト,インク. | 葉酸を標的とした診断及び処置 |
| JP2019043961A (ja) * | 2010-04-20 | 2019-03-22 | オクタファルマ・アーゲー | 医薬タンパク質の新規な安定化剤 |
| ES2639641T3 (es) | 2010-04-20 | 2017-10-27 | Octapharma Ag | Nuevo agente estabilizante para proteínas farmacéuticas |
| CN101885841B (zh) * | 2010-07-02 | 2012-05-16 | 清华大学 | 一种可与巯基发生加成反应且成键水解稳定的高分子 |
| WO2012021791A2 (en) * | 2010-08-13 | 2012-02-16 | Scidose Llc | Aqueous formulation with improved stability |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| PT2934568T (pt) | 2012-12-21 | 2018-01-04 | Sanofi Sa | Agonistas duplos de glp1/gip ou trigonais de glp1/gip/glucagina |
| WO2015077303A1 (en) | 2013-11-19 | 2015-05-28 | Purdue Research Foundation | Patient selection method for inflammation |
| TW201609795A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 作為雙重glp-1/gip受體促效劑的艾塞那肽-4(exendin-4)胜肽類似物 |
| TW201609796A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 非醯化之艾塞那肽-4(exendin-4)胜肽類似物 |
| TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/gip受體促效劑 |
| TW201609797A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/升糖素受體促效劑 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物 |
| WO2019040507A1 (en) * | 2017-08-21 | 2019-02-28 | Prevail Therapeutics, Inc. | MODIFIED LYSOSOMIAL ENZYMES |
| AU2019305215A1 (en) * | 2018-07-20 | 2021-02-25 | Hercules Llc | Water soluble or dispersible composition |
| CN115785473B (zh) * | 2022-12-20 | 2023-08-18 | 上海赛翠克环保科技有限公司 | 端异硫脲基三羟甲基丙烷芯树枝状聚合物及其制备方法和缓蚀应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1365481A (en) † | 1968-07-15 | 1974-09-04 | Ciba Geigy Uk Ltd | Process for keratinous fabric |
| DE2138448A1 (de) † | 1968-07-15 | 1972-02-17 | IWS Nominee Co Ltd , London, Ciba Geigy AG, Basel (Schweiz) | Behandlung von keratinhaltigen Materialien |
| GB1379203A (en) | 1970-12-14 | 1975-01-02 | Ciba Geigy Ag | Textile finishing |
| DE2238940A1 (de) | 1972-08-08 | 1974-02-21 | Bayer Ag | Permanent antistatische acrylnitrilpolymerisate |
| GB1435085A (en) † | 1972-09-01 | 1976-05-12 | Ciba Geigy Ag | Keratinous textiles and fibres |
| US3948820A (en) † | 1972-11-02 | 1976-04-06 | Horizons Incorporated | Curable polyphosphazene copolymers and terpolymers |
| CH902673A4 (enExample) † | 1973-06-21 | 1974-12-13 | ||
| DE58909681D1 (de) | 1988-11-23 | 1996-06-20 | Ciba Geigy Ag | Polyoxyalkylendithiole und Polyamine enthaltende härtbare Epoxidharz-Stoffgemische |
| DE59008799D1 (de) | 1989-11-21 | 1995-05-04 | Ciba Geigy Ag | Härtbare Epoxidharz-Stoffgemische enthaltend einen latenten Härter, ein Amin und ein Thiol. |
| US5516703A (en) | 1993-08-20 | 1996-05-14 | The University Of Utah | Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands |
| US5446090A (en) | 1993-11-12 | 1995-08-29 | Shearwater Polymers, Inc. | Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules |
| US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| US5580923A (en) | 1995-03-14 | 1996-12-03 | Collagen Corporation | Anti-adhesion films and compositions for medical use |
| US6306584B1 (en) | 1997-01-21 | 2001-10-23 | President And Fellows Of Harvard College | Electronic-property probing of biological molecules at surfaces |
| JPH1138544A (ja) * | 1997-07-16 | 1999-02-12 | Konica Corp | ハロゲン化銀写真感光材料及びその処理方法 |
| NZ507456A (en) * | 1998-04-28 | 2003-10-31 | Applied Research Systems | Process and conjugated forms of PEGylated interferon- beta with polyethylene glycol (PEG) wherein the thiol reactive polyol agent is mono-methoxylated |
| TW593427B (en) * | 2000-12-18 | 2004-06-21 | Nektar Therapeutics Al Corp | Synthesis of high molecular weight non-peptidic polymer derivatives |
| US7053150B2 (en) | 2000-12-18 | 2006-05-30 | Nektar Therapeutics Al, Corporation | Segmented polymers and their conjugates |
| MXPA04006855A (es) | 2002-01-18 | 2005-04-19 | Biogen Idec Inc | Compuestos de polimeros de polialquileno y usos de los mismos. |
| CN1511861A (zh) * | 2002-12-26 | 2004-07-14 | 北京键凯科技有限公司 | 聚乙二醇-脂肪酸衍生物及其药物结合物 |
| MXPA05007163A (es) | 2002-12-31 | 2005-09-21 | Nektar Therapeutics Al Corp | Derivados polimericos de acido maleamico y sus bioconjugados. |
| KR101025143B1 (ko) | 2002-12-31 | 2011-04-01 | 넥타르 테라퓨틱스 | 가수분해상으로 안정한 말레이미드-종결 중합체 |
| ATE485331T1 (de) | 2003-01-06 | 2010-11-15 | Nektar Therapeutics | Thiolselektive wasserlösliche polymerderivate |
| JP4109559B2 (ja) † | 2003-02-19 | 2008-07-02 | 独立行政法人科学技術振興機構 | オリゴヌクレオチドとポリエチレンオキシドのコンジュゲート |
| EP1609491B1 (en) * | 2004-06-16 | 2008-02-06 | Straumann Holding AG | Barrier membrane |
| CN101111267B (zh) | 2004-12-21 | 2012-12-05 | 尼克塔治疗公司 | 稳定的聚合物巯基试剂 |
| WO2007019331A2 (en) † | 2005-08-04 | 2007-02-15 | Nektar Therapeutics Al, Corporation | Conjugates of a g-csf moiety and a polymer |
| EP2364735A3 (en) † | 2005-12-16 | 2012-04-11 | Nektar Therapeutics | Branched PEG conjugates of GLP-1 |
| WO2010099533A1 (en) | 2009-02-27 | 2010-09-02 | Openlane, Inc. | Wholesale virtual inventory and retail lead generation |
-
2005
- 2005-12-21 CN CN2005800475071A patent/CN101111267B/zh not_active Expired - Lifetime
- 2005-12-21 CA CA2591233A patent/CA2591233C/en not_active Expired - Lifetime
- 2005-12-21 AU AU2005318984A patent/AU2005318984B2/en not_active Expired
- 2005-12-21 JP JP2007548599A patent/JP5243041B2/ja not_active Expired - Lifetime
- 2005-12-21 AT AT05855832T patent/ATE494012T1/de not_active IP Right Cessation
- 2005-12-21 US US11/316,051 patent/US7851565B2/en active Active
- 2005-12-21 EP EP05855832.1A patent/EP1827501B2/en not_active Expired - Lifetime
- 2005-12-21 KR KR1020077014146A patent/KR101320936B1/ko not_active Expired - Lifetime
- 2005-12-21 DE DE602005025805T patent/DE602005025805D1/de not_active Expired - Lifetime
- 2005-12-21 WO PCT/US2005/047337 patent/WO2006069388A2/en not_active Ceased
- 2005-12-21 ES ES05855832.1T patent/ES2357089T5/es not_active Expired - Lifetime
- 2005-12-21 MX MX2007007471A patent/MX2007007471A/es active IP Right Grant
-
2010
- 2010-11-10 US US12/943,740 patent/US8217123B2/en not_active Expired - Lifetime
-
2012
- 2012-06-20 US US13/528,103 patent/US8492488B2/en not_active Expired - Lifetime
-
2013
- 2013-06-19 US US13/921,889 patent/US8765883B2/en not_active Expired - Lifetime
-
2014
- 2014-05-19 US US14/281,411 patent/US9308274B2/en not_active Expired - Lifetime
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