JP2008522628A - 高品質核酸のセルフリー生合成及びその使用 - Google Patents

高品質核酸のセルフリー生合成及びその使用 Download PDF

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JP2008522628A
JP2008522628A JP2007545717A JP2007545717A JP2008522628A JP 2008522628 A JP2008522628 A JP 2008522628A JP 2007545717 A JP2007545717 A JP 2007545717A JP 2007545717 A JP2007545717 A JP 2007545717A JP 2008522628 A JP2008522628 A JP 2008522628A
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dna
amplification
nucleic acid
reaction
template
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JP2008522628A5 (enExample
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イェン チェン，
フレデリック ケンダーギ，
フランク ヴァスケス，
マルコム スコルニック，
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サイトジェニックス， インコーポレイテッド
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/10—Nucleotidyl transfering
    • C12Q2521/101—DNA polymerase

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  • Virology (AREA)
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  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2007545717A 2004-12-11 2005-12-12 高品質核酸のセルフリー生合成及びその使用 Pending JP2008522628A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US63541804P 2004-12-11 2004-12-11
US68071605P 2005-05-13 2005-05-13
US70534805P 2005-08-04 2005-08-04
PCT/US2005/045028 WO2006063355A2 (en) 2004-12-11 2005-12-12 Cell free biosynthesis of high-quality nucleic acid and uses thereof

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JP2008522628A true JP2008522628A (ja) 2008-07-03
JP2008522628A5 JP2008522628A5 (enExample) 2008-11-20

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US (1) US20080305142A1 (enExample)
EP (1) EP1819828A2 (enExample)
JP (1) JP2008522628A (enExample)
KR (1) KR20070093992A (enExample)
AU (1) AU2005314431B2 (enExample)
BR (1) BRPI0515777A (enExample)
CA (1) CA2590933A1 (enExample)
IL (1) IL183778A0 (enExample)
WO (1) WO2006063355A2 (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011125848A1 (ja) * 2010-03-31 2011-10-13 テルモ株式会社 リポソーム製剤の製造方法
JP2013535210A (ja) * 2010-08-04 2013-09-12 タッチライト ジェネティックス リミテッド パリンドローム配列を用いた閉鎖型直鎖状ｄｎａの生成
JP2015091236A (ja) * 2008-09-02 2015-05-14 ゼネラル・エレクトリック・カンパニイ Ｄｎａミニサークルおよびその使用
JP2016047049A (ja) * 2009-01-30 2016-04-07 タッチライト ジェネティクス リミテッド 閉鎖型直鎖状ｄｎａの製造
JP2019516368A (ja) * 2016-05-04 2019-06-20 ゼネラル・エレクトリック・カンパニイ ローリングサークル増幅産物を使用した無細胞タンパク質発現
JP2020533964A (ja) * 2017-08-11 2020-11-26 ゼネラル・エレクトリック・カンパニイ 二本鎖コンカテマーｄｎａを使用したセルフリータンパク質発現
JP2023514422A (ja) * 2020-02-24 2023-04-05 モリゴ・テクノロジーズ・アクチエボラグ 一本鎖ｄｎａポリヌクレオチドを生成するための方法および生成物

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AU2008307617B2 (en) * 2007-09-28 2013-05-23 Pacific Biosciences Of California, Inc. Error-free amplification of DNA for clonal sequencing
FR2924440B1 (fr) * 2007-12-04 2015-01-09 Pf Medicament Nouveau procede de generation et de criblage d'une banque d'anticorps
US9125845B2 (en) 2008-07-09 2015-09-08 General Electric Company DNA vaccines, uses for unprocessed rolling circle amplification product and methods for making the same
US20100008939A1 (en) * 2008-07-09 2010-01-14 General Electric Company Unprocessed rolling circle amplification product
US10350307B2 (en) 2017-09-18 2019-07-16 General Electric Company In vivo RNA or protein expression using double-stranded concatemeric DNA including phosphorothioated nucleotides
GB201901583D0 (en) * 2019-02-05 2019-03-27 Ducani Cosimo Method and products for producing funtionaslised single stranded oligonucleotides
JP2022549138A (ja) 2019-09-18 2022-11-24 インターガラクティック セラピューティクス インコーポレイテッド 合成ｄｎａベクターおよびその使用法
CN115175998A (zh) * 2019-10-18 2022-10-11 Encodia 公司 分析用大分子的自动化处理及相关设备
EP4083227A1 (en) * 2021-04-29 2022-11-02 4basebio, S.L.U. Linear dna with enhanced resistance against exonucleases
US20240409975A1 (en) * 2021-09-27 2024-12-12 Intergalactic Therapeutics, Inc. Synthetic production of circular dna vectors
EP4419677A4 (en) 2021-10-18 2025-09-24 Flagship Pioneering Innovations Vii Llc DNA COMPOSITIONS AND RELATED METHODS
EP4310182A1 (en) * 2022-07-19 2024-01-24 4basebio UK Ltd Protected dna and methods for the production thereof
WO2025175112A1 (en) * 2024-02-16 2025-08-21 University Of Maryland, Baltimore County Method for generating circular dna using heteroduplex thermostable ligation assembly of precursors produced by rolling circle amplification

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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015091236A (ja) * 2008-09-02 2015-05-14 ゼネラル・エレクトリック・カンパニイ Ｄｎａミニサークルおよびその使用
JP2016047049A (ja) * 2009-01-30 2016-04-07 タッチライト ジェネティクス リミテッド 閉鎖型直鎖状ｄｎａの製造
WO2011125848A1 (ja) * 2010-03-31 2011-10-13 テルモ株式会社 リポソーム製剤の製造方法
JP2013535210A (ja) * 2010-08-04 2013-09-12 タッチライト ジェネティックス リミテッド パリンドローム配列を用いた閉鎖型直鎖状ｄｎａの生成
JP2017035102A (ja) * 2010-08-04 2017-02-16 タッチライト ジェネティックス リミテッド パリンドローム配列を用いた閉鎖型直鎖状ｄｎａの生成
JP7058839B2 (ja) 2016-05-04 2022-04-25 グローバル・ライフ・サイエンシズ・ソリューションズ・オペレーションズ・ユーケー・リミテッド ローリングサークル増幅産物を使用した無細胞タンパク質発現
JP2019516368A (ja) * 2016-05-04 2019-06-20 ゼネラル・エレクトリック・カンパニイ ローリングサークル増幅産物を使用した無細胞タンパク質発現
JP2022037230A (ja) * 2016-05-04 2022-03-08 グローバル・ライフ・サイエンシズ・ソリューションズ・オペレーションズ・ユーケー・リミテッド ローリングサークル増幅産物を使用した無細胞タンパク質発現
JP2020533964A (ja) * 2017-08-11 2020-11-26 ゼネラル・エレクトリック・カンパニイ 二本鎖コンカテマーｄｎａを使用したセルフリータンパク質発現
JP2023052556A (ja) * 2017-08-11 2023-04-11 グローバル・ライフ・サイエンシズ・ソリューションズ・オペレーションズ・ユーケー・リミテッド 二本鎖コンカテマーｄｎａを使用したセルフリータンパク質発現
JP7258361B2 (ja) 2017-08-11 2023-04-17 グローバル・ライフ・サイエンシズ・ソリューションズ・オペレーションズ・ユーケー・リミテッド 二本鎖コンカテマーｄｎａを使用したセルフリータンパク質発現
JP2023514422A (ja) * 2020-02-24 2023-04-05 モリゴ・テクノロジーズ・アクチエボラグ 一本鎖ｄｎａポリヌクレオチドを生成するための方法および生成物
JP7699390B2 (ja) 2020-02-24 2025-06-27 モリゴ・テクノロジーズ・アクチエボラグ 一本鎖ｄｎａポリヌクレオチドを生成するための方法および生成物

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AU2005314431A1 (en) 2006-06-15
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US20080305142A1 (en) 2008-12-11
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