AU2005314431B2 - Cell free biosynthesis of high-quality nucleic acid and uses thereof - Google Patents
Cell free biosynthesis of high-quality nucleic acid and uses thereof Download PDFInfo
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- AU2005314431B2 AU2005314431B2 AU2005314431A AU2005314431A AU2005314431B2 AU 2005314431 B2 AU2005314431 B2 AU 2005314431B2 AU 2005314431 A AU2005314431 A AU 2005314431A AU 2005314431 A AU2005314431 A AU 2005314431A AU 2005314431 B2 AU2005314431 B2 AU 2005314431B2
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- A61P31/18—Antivirals for RNA viruses for HIV
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/101—DNA polymerase
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| US60/680,716 | 2005-05-13 | ||
| US70534805P | 2005-08-04 | 2005-08-04 | |
| US60/705,348 | 2005-08-04 | ||
| PCT/US2005/045028 WO2006063355A2 (en) | 2004-12-11 | 2005-12-12 | Cell free biosynthesis of high-quality nucleic acid and uses thereof |
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| WO2007018744A2 (en) * | 2005-08-03 | 2007-02-15 | Cytogenix, Inc. | Cell-free biosynthesis of nucleic acid |
| GB0614825D0 (en) * | 2006-07-26 | 2006-09-06 | Medical Res Council | Method for amplification of ligation reactions |
| WO2009045344A2 (en) | 2007-09-28 | 2009-04-09 | Pacific Biosciences Of California, Inc. | Error-free amplification of dna for clonal sequencing |
| FR2924440B1 (fr) | 2007-12-04 | 2015-01-09 | Pf Medicament | Nouveau procede de generation et de criblage d'une banque d'anticorps |
| US20100008939A1 (en) * | 2008-07-09 | 2010-01-14 | General Electric Company | Unprocessed rolling circle amplification product |
| US9125845B2 (en) | 2008-07-09 | 2015-09-08 | General Electric Company | DNA vaccines, uses for unprocessed rolling circle amplification product and methods for making the same |
| US8921072B2 (en) * | 2008-09-02 | 2014-12-30 | General Electric Compnay | Methods to generate DNA mini-circles |
| GB0901593D0 (en) | 2009-01-30 | 2009-03-11 | Touchlight Genetics Ltd | Production of closed linear DNA |
| JP2013126953A (ja) * | 2010-03-31 | 2013-06-27 | Terumo Corp | リポソーム製剤の製造方法 |
| GB201013153D0 (en) * | 2010-08-04 | 2010-09-22 | Touchlight Genetics Ltd | Primer for production of closed linear DNA |
| US10077459B2 (en) | 2016-05-04 | 2018-09-18 | General Electric Company | Cell-free protein expression using rolling circle amplification product |
| US11001868B2 (en) * | 2017-08-11 | 2021-05-11 | Global Life Sciences Solutions Operations UK Ltd | Cell-free protein expression using double-stranded concatameric DNA |
| US10350307B2 (en) | 2017-09-18 | 2019-07-16 | General Electric Company | In vivo RNA or protein expression using double-stranded concatemeric DNA including phosphorothioated nucleotides |
| GB201901583D0 (en) * | 2019-02-05 | 2019-03-27 | Ducani Cosimo | Method and products for producing funtionaslised single stranded oligonucleotides |
| CN115066255A (zh) | 2019-09-18 | 2022-09-16 | 星际治疗有限公司 | 合成的dna载体和使用方法 |
| WO2021076648A1 (en) * | 2019-10-18 | 2021-04-22 | Encodia, Inc. | Automated treatment of macromolecules for analysis and related apparatus |
| GB202002547D0 (en) * | 2020-02-24 | 2020-04-08 | Moligo Tech Ab | Method and products for producing single stranded DNA polynucleotides |
| EP4083227A1 (en) * | 2021-04-29 | 2022-11-02 | 4basebio, S.L.U. | Linear dna with enhanced resistance against exonucleases |
| KR20240126447A (ko) * | 2021-09-27 | 2024-08-20 | 인터갈락틱 테라퓨틱스, 인크. | 원형 dna 벡터의 합성 생산 |
| EP4419677A4 (en) | 2021-10-18 | 2025-09-24 | Flagship Pioneering Innovations Vii Llc | DNA COMPOSITIONS AND RELATED METHODS |
| EP4310182A1 (en) * | 2022-07-19 | 2024-01-24 | 4basebio UK Ltd | Protected dna and methods for the production thereof |
| WO2025175112A1 (en) * | 2024-02-16 | 2025-08-21 | University Of Maryland, Baltimore County | Method for generating circular dna using heteroduplex thermostable ligation assembly of precursors produced by rolling circle amplification |
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| US20080305142A1 (en) | 2008-12-11 |
| CA2590933A1 (en) | 2006-06-15 |
| AU2005314431A1 (en) | 2006-06-15 |
| JP2008522628A (ja) | 2008-07-03 |
| EP1819828A2 (en) | 2007-08-22 |
| WO2006063355A2 (en) | 2006-06-15 |
| BRPI0515777A (pt) | 2008-08-05 |
| WO2006063355A3 (en) | 2006-10-19 |
| KR20070093992A (ko) | 2007-09-19 |
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