|
US4321378A
(en)
*
|
1979-01-16 |
1982-03-23 |
Delalande S.A. |
8-(5-Pyrimidinecarboxamide)nor-tropane derivatives
|
|
US4937247A
(en)
*
|
1985-04-27 |
1990-06-26 |
Beecham Group P.L.C. |
1-acyl indazoles
|
|
GB8527052D0
(en)
*
|
1985-11-02 |
1985-12-04 |
Beecham Group Plc |
Compounds
|
|
US4772706A
(en)
*
|
1986-01-13 |
1988-09-20 |
Warner-Lambert Company |
Process for quinoline-3-carboxylic acid antibacterial agents
|
|
HU202108B
(en)
*
|
1986-07-30 |
1991-02-28 |
Sandoz Ag |
Process for producing pharmaceutical compositions containing serotonine antqgonistic derivatives of indol-carboxylic acid or imidazolyl-methyl-carbazol
|
|
DE3777805D1
(de)
*
|
1986-11-21 |
1992-04-30 |
Glaxo Group Ltd |
Arzneimittel zur behandlung oder vorbeugung des entzugssyndromes.
|
|
GB8701022D0
(en)
*
|
1987-01-19 |
1987-02-18 |
Beecham Group Plc |
Treatment
|
|
US5223511A
(en)
*
|
1987-09-23 |
1993-06-29 |
Boehringer Ingelheim Italia S.P.A. |
Benzimidazoline-2-oxo-1-carboxylic acid compounds useful as 5-HT receptor antagonists
|
|
IT1231413B
(it)
|
1987-09-23 |
1991-12-04 |
Angeli Inst Spa |
Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht
|
|
IT1226389B
(it)
*
|
1988-07-12 |
1991-01-15 |
Angeli Inst Spa |
Nuovi derivati ammidinici e guanidinici
|
|
NZ230068A
(en)
*
|
1988-07-29 |
1991-07-26 |
Dainippon Pharmaceutical Co |
Indazole-3-carboxylic acid esters and amides of diaza compounds having 6,7, or 8 ring members: preparatory processes and pharmaceutical compositions
|
|
EP0410509A1
(en)
*
|
1989-07-25 |
1991-01-30 |
Duphar International Research B.V |
New substituted 1H-indazole-3-carboxamides
|
|
GB2236751B
(en)
*
|
1989-10-14 |
1993-04-28 |
Wyeth John & Brother Ltd |
Heterocyclic compounds
|
|
JPH045289A
(ja)
|
1990-04-24 |
1992-01-09 |
Hokuriku Seiyaku Co Ltd |
アミド化合物
|
|
JP3122671B2
(ja)
*
|
1990-05-23 |
2001-01-09 |
協和醗酵工業株式会社 |
複素環式化合物
|
|
HU211081B
(en)
*
|
1990-12-18 |
1995-10-30 |
Sandoz Ag |
Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
|
|
CA2097815C
(en)
*
|
1990-12-28 |
2001-04-17 |
Fumio Suzuki |
Quinoline derivative
|
|
US5096410A
(en)
*
|
1991-02-19 |
1992-03-17 |
Demetre Loulourgas |
Water jacketed sprue bushing
|
|
PT100785A
(pt)
|
1991-08-20 |
1994-04-29 |
Smithkline Beecham Plc |
Utilizacao de compostos, por exemplo indole-3-carboxilatos, para a producao de medicamentos, compostos ai utilizados e composicoes farmaceuticas que os contem.
|
|
CA2118798A1
(en)
*
|
1991-09-12 |
1993-03-18 |
Francis D. King |
Azabicyclic compounds as 5-ht4 receptor antagonists
|
|
MX9305947A
(es)
*
|
1992-09-29 |
1994-06-30 |
Smithkline Beecham Plc |
Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
|
|
EP0670319A4
(en)
*
|
1992-11-20 |
1996-01-17 |
Thaisho Pharmaceutical Co Ltd |
HETEROCYCLIC COMPOUNDS.
|
|
TW251287B
(enExample)
|
1993-04-30 |
1995-07-11 |
Nissei Co Ltd |
|
|
GB9310582D0
(en)
*
|
1993-05-22 |
1993-07-07 |
Smithkline Beecham Plc |
Pharmaceuticals
|
|
WO1995023147A1
(en)
*
|
1994-02-28 |
1995-08-31 |
Taisho Pharmaceutical Co., Ltd. |
Heterocyclic compound
|
|
US5864039A
(en)
*
|
1994-03-30 |
1999-01-26 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Benzoic acid compounds and use thereof as medicaments
|
|
GB9406857D0
(en)
*
|
1994-04-07 |
1994-06-01 |
Sandoz Ltd |
Improvements in or relating to organic compounds
|
|
JP3829879B2
(ja)
*
|
1994-05-18 |
2006-10-04 |
大正製薬株式会社 |
キノリンカルボン酸誘導体
|
|
CA2160420A1
(en)
*
|
1994-10-20 |
1996-04-21 |
Haruhiko Kikuchi |
5-ht4 receptor agonists
|
|
JP3829880B2
(ja)
|
1994-12-27 |
2006-10-04 |
大正製薬株式会社 |
化学中間体
|
|
JP3888393B2
(ja)
*
|
1995-03-10 |
2007-02-28 |
大正製薬株式会社 |
キノロン誘導体
|
|
IT1275903B1
(it)
*
|
1995-03-14 |
1997-10-24 |
Boehringer Ingelheim Italia |
Esteri e ammidi della 1,4-piperidina disostituita
|
|
US5654320A
(en)
*
|
1995-03-16 |
1997-08-05 |
Eli Lilly And Company |
Indazolecarboxamides
|
|
WO1996038420A1
(en)
*
|
1995-05-31 |
1996-12-05 |
Nisshin Flour Milling Co., Ltd. |
Indazole derivatives having monocyclic amino group
|
|
JPH09194374A
(ja)
*
|
1995-11-14 |
1997-07-29 |
Taisho Pharmaceut Co Ltd |
消化器疾患治療剤
|
|
ES2109190B1
(es)
|
1996-03-22 |
1998-07-01 |
Univ Madrid Complutense |
Nuevos derivados de bencimidazol con afinidad por los receptores serotoninergicos 5-ht /5-ht
|
|
IT1291569B1
(it)
*
|
1997-04-15 |
1999-01-11 |
Angelini Ricerche Spa |
Indazolammidi come agenti serotoninergici
|
|
TW402591B
(en)
*
|
1997-07-11 |
2000-08-21 |
Janssen Pharmaceutica Nv |
Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
|
|
US6069152A
(en)
*
|
1997-10-07 |
2000-05-30 |
Eli Lilly And Company |
5-HT4 agonists and antagonists
|
|
US5914405A
(en)
*
|
1997-10-07 |
1999-06-22 |
Eli Lilly And Company |
Process for preparing 3-substituted indazoles
|
|
FR2769915B1
(fr)
|
1997-10-21 |
2000-10-13 |
Synthelabo |
Derives d'indazole tricycliques, leur preparation et leur application en therapeutique
|
|
IT1298271B1
(it)
|
1998-02-18 |
1999-12-20 |
Boehringer Ingelheim Italia |
Esteri ed ammidi dell'acido 2-oxo-2,3-diidro-benzimidazol-1- carbossilico
|
|
EP1076055B1
(en)
*
|
1998-04-28 |
2004-11-24 |
Dainippon Pharmaceutical Co., Ltd. |
1- (1-substituted-4-piperidinyl)methyl]-4-piperidine derivatives, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
|
|
KR100413150B1
(ko)
*
|
1998-09-10 |
2003-12-31 |
에프. 호프만-라 로슈 아게 |
5-에이치티4 수용체 길항제로서의 디하이드로벤조디옥신 카복스아미드 및 케톤 유도체
|
|
TW570920B
(en)
*
|
1998-12-22 |
2004-01-11 |
Janssen Pharmaceutica Nv |
4-(aminomethyl)-piperidine benzamides for treating gastrointestinal disorders
|
|
FR2792318B1
(fr)
|
1999-04-16 |
2001-06-15 |
Synthelabo |
Derives d'indazole, leur preparation et leur application en therapeutique
|
|
EP1173168A2
(en)
*
|
1999-04-28 |
2002-01-23 |
Respiratorius AB |
Compound for use as a medicament for treatment of disorders involving bronchocontraction
|
|
ES2154605B1
(es)
|
1999-09-14 |
2001-11-16 |
Univ Madrid Complutense |
Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3
|
|
IT1313625B1
(it)
*
|
1999-09-22 |
2002-09-09 |
Boehringer Ingelheim Italia |
Derivati benzimidazolonici aventi affinita' mista per i recettori diserotonina e dopamina.
|
|
IT1313660B1
(it)
|
1999-10-01 |
2002-09-09 |
Dompe Spa |
Procedimento stereoselettivo per la preparazione di endo-3-amminoazabicicloalcani.
|
|
WO2002036113A1
(en)
|
2000-11-01 |
2002-05-10 |
Respiratorius Ab |
Composition comprising: serotonin receptor antagonists (5ht-2, 5ht-3) and agonist (5ht-4)
|
|
US6624162B2
(en)
*
|
2001-10-22 |
2003-09-23 |
Pfizer Inc. |
Imidazopyridine compounds as 5-HT4 receptor modulators
|
|
MXPA03000145A
(es)
*
|
2002-01-07 |
2003-07-15 |
Pfizer |
Compuestos de oxo u oxi-piridina como moduladores de receptores 5-ht4.
|
|
US6696468B2
(en)
*
|
2002-05-16 |
2004-02-24 |
Dainippon Pharmaceutical Co., Ltd. |
(s)-4-amino-5-chloro-2-methoxy-n-[1-[1-(2-tetrahydrofuryl-carbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor
|
|
DOP2003000703A
(es)
*
|
2002-09-20 |
2004-03-31 |
Pfizer |
Compuestos de imidazopiradina como agonistas del receptor 5-ht4
|
|
JP2006502180A
(ja)
*
|
2002-09-20 |
2006-01-19 |
ファイザー株式会社 |
５−ｈｔ４レセプターモジュレーターとしてのｎ−置換されたピペリジニル−イミダゾピリジン化合物
|
|
BRPI0409592A
(pt)
*
|
2003-04-21 |
2006-05-02 |
Pfizer |
compostos imidazopiridina tendo atividade agonìstica do receptor 5-ht4 e atividade antagonìstica do receptor 5-ht3
|
|
US7652040B2
(en)
|
2003-06-19 |
2010-01-26 |
Janssen Pharmaceutica N.V. |
Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists
|
|
JO2478B1
(en)
|
2003-06-19 |
2009-01-20 |
جانسين فارماسوتيكا ان. في. |
(Aminomethyl) -biperidine benzamides as 5 HT4 antagonists
|
|
DK1664036T3
(da)
|
2003-09-03 |
2012-02-13 |
Pfizer |
Benzimidazolonforbindelser med 5-HT4-receptoragonistisk virkning
|
|
WO2005049608A1
(en)
|
2003-11-24 |
2005-06-02 |
Pfizer Japan, Inc. |
Quinolonecarboxylic acid compounds having 5-ht4 receptor agonistic activity
|
|
EP1713797B1
(en)
|
2004-01-29 |
2008-03-05 |
Pfizer, Inc. |
1-isopropyl-2-oxo-1,2-dihydropyridine-3-carboxamide derivatives having 5-ht4 receptor agonistic activity
|
|
TW200533348A
(en)
*
|
2004-02-18 |
2005-10-16 |
Theravance Inc |
Indazole-carboxamide compounds as 5-ht4 receptor agonists
|
|
WO2005092882A1
(en)
|
2004-03-01 |
2005-10-06 |
Pfizer Japan, Inc. |
4-amino-5-halogeno-benzamide derivatives as 5-ht4 receptor agonists for the treatment of gastrointestinal, cns, neurological and cardiovascular disorders
|
|
US7728006B2
(en)
|
2004-04-07 |
2010-06-01 |
Theravance, Inc. |
Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
|
|
TWI351282B
(en)
*
|
2004-04-07 |
2011-11-01 |
Theravance Inc |
Quinolinone-carboxamide compounds as 5-ht4 recepto
|
|
US7737163B2
(en)
*
|
2004-06-15 |
2010-06-15 |
Pfizer Inc. |
Benzimidazolone carboxylic acid derivatives
|
|
MXPA06014486A
(es)
*
|
2004-06-15 |
2007-03-01 |
Pfizer |
Derivados de acido carboxilico de bencimidazolona.
|
|
ATE431824T1
(de)
|
2004-11-05 |
2009-06-15 |
Theravance Inc |
Chinolinon-carboxamid-verbindungen
|
|
ATE441646T1
(de)
*
|
2004-11-05 |
2009-09-15 |
Theravance Inc |
5-ht4-rezeptoragonistenverbindungen
|
|
WO2006069125A1
(en)
*
|
2004-12-22 |
2006-06-29 |
Theravance, Inc. |
Indazole-carboxamide compounds
|
|
TWI377206B
(en)
|
2005-04-06 |
2012-11-21 |
Theravance Inc |
Crystalline form of a quinolinone-carboxamide compound
|
|
ATE495171T1
(de)
|
2005-06-07 |
2011-01-15 |
Theravance Inc |
Benzimidazoloncarbonsäureamidverbindungen als agonisten des 5-ht4-rezeptors
|