FR2911874B1 - Derives d'urees de tropane, leur preparation et leur application en therapeutique - Google Patents

Derives d'urees de tropane, leur preparation et leur application en therapeutique

Info

Publication number
FR2911874B1
FR2911874B1 FR0700507A FR0700507A FR2911874B1 FR 2911874 B1 FR2911874 B1 FR 2911874B1 FR 0700507 A FR0700507 A FR 0700507A FR 0700507 A FR0700507 A FR 0700507A FR 2911874 B1 FR2911874 B1 FR 2911874B1
Authority
FR
France
Prior art keywords
urees
tropane
derivatives
preparation
therapeutic application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0700507A
Other languages
English (en)
Other versions
FR2911874A1 (fr
Inventor
Michel Aletru
Alain Jean Braun
Stefan Gussregen
Patrick Mougenot
Claudie Suzanne Yvette Namane
Eric Nicolai
Christophe Philippo
Olivier Claude George Venier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to FR0700507A priority Critical patent/FR2911874B1/fr
Priority to TW096122891A priority patent/TW200811170A/zh
Priority to PE2007000811A priority patent/PE20080344A1/es
Priority to KR1020087031631A priority patent/KR20090021193A/ko
Priority to SI200730258T priority patent/SI2046791T1/sl
Priority to AU2007264792A priority patent/AU2007264792A1/en
Priority to DK07803782.7T priority patent/DK2046791T3/da
Priority to AT07803782T priority patent/ATE461930T1/de
Priority to PT07803782T priority patent/PT2046791E/pt
Priority to EP07803782A priority patent/EP2046791B1/fr
Priority to CA002648769A priority patent/CA2648769A1/fr
Priority to DE602007005487T priority patent/DE602007005487D1/de
Priority to MX2008016492A priority patent/MX277822B/es
Priority to ARP070102821A priority patent/AR061642A1/es
Priority to PL07803782T priority patent/PL2046791T3/pl
Priority to RU2009102535/04A priority patent/RU2009102535A/ru
Priority to PCT/FR2007/001070 priority patent/WO2008000951A2/fr
Priority to JP2009517319A priority patent/JP2009541464A/ja
Priority to ES07803782T priority patent/ES2342793T3/es
Priority to CL2007001885A priority patent/CL2007001885A1/es
Priority to UY30447A priority patent/UY30447A1/es
Publication of FR2911874A1 publication Critical patent/FR2911874A1/fr
Priority to IL195510A priority patent/IL195510A0/en
Priority to US12/332,547 priority patent/US7897773B2/en
Application granted granted Critical
Publication of FR2911874B1 publication Critical patent/FR2911874B1/fr
Priority to CY20101100571T priority patent/CY1110132T1/el
Priority to US12/871,403 priority patent/US20100324084A1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0700507A 2006-06-27 2007-01-25 Derives d'urees de tropane, leur preparation et leur application en therapeutique Expired - Fee Related FR2911874B1 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR0700507A FR2911874B1 (fr) 2007-01-25 2007-01-25 Derives d'urees de tropane, leur preparation et leur application en therapeutique
PE2007000811A PE20080344A1 (es) 2006-06-27 2007-06-25 Compuestos 8-azabiciclo[3.2.1]oct-8-il-1,2,3,4-tetrahidroquinolina sustituidos como inhibidores 11b-hsd1
TW096122891A TW200811170A (en) 2006-06-27 2007-06-25 Urea derivatives of tropane, their preparation and their therapeutic application
PCT/FR2007/001070 WO2008000951A2 (fr) 2006-06-27 2007-06-26 Dérivés d'urees de tropane, leur préparation et leur application en thérapeutique
AU2007264792A AU2007264792A1 (en) 2006-06-27 2007-06-26 Urea derivatives of tropane, their preparation and their therapeutic application
DK07803782.7T DK2046791T3 (da) 2006-06-27 2007-06-26 Ureaderivater af tropan, fremstilling deraf og terepeutisk anvendelse deraf
AT07803782T ATE461930T1 (de) 2006-06-27 2007-06-26 Harnstoffderivate von tropan, ihre herstellung und ihre therapeutische anwendung
PT07803782T PT2046791E (pt) 2006-06-27 2007-06-26 Derivados de ureias de tropano, sua preparação e sua aplicação em terapêutica
EP07803782A EP2046791B1 (fr) 2006-06-27 2007-06-26 Dérivés d'urees de tropane, leur préparation et leur application en thérapeutique
CA002648769A CA2648769A1 (fr) 2006-06-27 2007-06-26 Derives d'urees de tropane, leur preparation et leur application en therapeutique
DE602007005487T DE602007005487D1 (de) 2006-06-27 2007-06-26 Harnstoffderivate von tropan, ihre herstellung und ihre therapeutische anwendung
MX2008016492A MX277822B (es) 2006-06-27 2007-06-26 Derivados de urea de tropano, su preparacion y su aplicacion terapeutica.
KR1020087031631A KR20090021193A (ko) 2006-06-27 2007-06-26 트로판의 우레아 유도체, 그의 제법 및 그의 치료 용도
PL07803782T PL2046791T3 (pl) 2006-06-27 2007-06-26 Mocznikowe pochodne tropanu, ich wytwarzanie i ich zastosowanie w lecznictwie
RU2009102535/04A RU2009102535A (ru) 2006-06-27 2007-06-26 Производные карбамидов тропана, их получение и их применение в терапии
SI200730258T SI2046791T1 (sl) 2006-06-27 2007-06-26 Sečninski derivati tropana, njihova priprava in njihova terapevtska uporaba
JP2009517319A JP2009541464A (ja) 2006-06-27 2007-06-26 トロパンの尿素誘導体、その調製およびその治療用途
ES07803782T ES2342793T3 (es) 2006-06-27 2007-06-26 Derivados de ureas de tropano, su preparacion y su aplicacion en terapeutica.
CL2007001885A CL2007001885A1 (es) 2006-06-27 2007-06-26 Compuestos derivados de urea de tropano, moduladores de la actividad de la 11betahsd1; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento de enfermedades tales como obesidad, diabetes, hipertension, aterosclerosis, demencia y osteoporosis.
ARP070102821A AR061642A1 (es) 2006-06-27 2007-06-26 Derivados de ureas de tropano, su preparacion y su aplicacion en terapeu-tica, procesos de obtencion y composiciones farmaceuticas
UY30447A UY30447A1 (es) 2006-06-27 2007-06-27 Derivados de ureas de tropano, su preparacion y su aplicacion en terapéutica
IL195510A IL195510A0 (en) 2006-06-27 2008-11-25 Urea derivatives of tropane, their preparation and their therapeutic application
US12/332,547 US7897773B2 (en) 2006-06-27 2008-12-11 Urea derivatives of tropane, their preparation and their therapeutic application
CY20101100571T CY1110132T1 (el) 2006-06-27 2010-06-21 Παραγωγα ουριας τροπανιου, η παρασκευη τους και οι εφαρμογες τους στη θεραπευτικη
US12/871,403 US20100324084A1 (en) 2006-06-27 2010-08-30 Urea derivatives of tropane, their preparation and their therapeutic application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0700507A FR2911874B1 (fr) 2007-01-25 2007-01-25 Derives d'urees de tropane, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2911874A1 FR2911874A1 (fr) 2008-08-01
FR2911874B1 true FR2911874B1 (fr) 2009-03-06

Family

ID=38283192

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0700507A Expired - Fee Related FR2911874B1 (fr) 2006-06-27 2007-01-25 Derives d'urees de tropane, leur preparation et leur application en therapeutique

Country Status (1)

Country Link
FR (1) FR2911874B1 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1263758A2 (fr) * 2000-03-03 2002-12-11 Ortho-McNeil Pharmaceutical, Inc. Derives de 3-(diarylmethylene)-8-azabicyclo 3.2.1]octane
JP2006521359A (ja) * 2003-03-26 2006-09-21 メルク　エンド　カムパニー　インコーポレーテッド メラノコルチン−４受容体作働薬としての二環式ピペリジン誘導体
JP2008515972A (ja) * 2004-10-13 2008-05-15 ニューロジェン・コーポレーション メラニン濃縮ホルモン受容体のリガンドとしてのアリール置換８−アザビシクロ［３．２．１］オクタン化合物
WO2006052889A2 (fr) * 2004-11-05 2006-05-18 Theravance, Inc. Composes de quinolinone-carboxamide

Also Published As

Publication number Publication date
FR2911874A1 (fr) 2008-08-01

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Effective date: 20160930