JP2008511654A5 - - Google Patents
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- Publication number
- JP2008511654A5 JP2008511654A5 JP2007530269A JP2007530269A JP2008511654A5 JP 2008511654 A5 JP2008511654 A5 JP 2008511654A5 JP 2007530269 A JP2007530269 A JP 2007530269A JP 2007530269 A JP2007530269 A JP 2007530269A JP 2008511654 A5 JP2008511654 A5 JP 2008511654A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- optionally substituted
- propyl
- trihydropurine
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60667504P | 2004-09-01 | 2004-09-01 | |
| US60/606,675 | 2004-09-01 | ||
| PCT/US2005/030838 WO2006028810A2 (en) | 2004-09-01 | 2005-08-30 | Method of wound healing using a2b adenosine receptor antagonists |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011195497A Division JP2011246492A (ja) | 2004-09-01 | 2011-09-07 | Ａ２ｂアデノシンレセプターアンタゴニストを使用する創傷治癒の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008511654A JP2008511654A (ja) | 2008-04-17 |
| JP2008511654A5 true JP2008511654A5 (enExample) | 2008-09-18 |
| JP4929173B2 JP4929173B2 (ja) | 2012-05-09 |
Family
ID=35695744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007530269A Expired - Lifetime JP4929173B2 (ja) | 2004-09-01 | 2005-08-30 | Ａ２ｂアデノシンレセプターアンタゴニストを使用する創傷治癒の方法 |
| JP2011195497A Withdrawn JP2011246492A (ja) | 2004-09-01 | 2011-09-07 | Ａ２ｂアデノシンレセプターアンタゴニストを使用する創傷治癒の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011195497A Withdrawn JP2011246492A (ja) | 2004-09-01 | 2011-09-07 | Ａ２ｂアデノシンレセプターアンタゴニストを使用する創傷治癒の方法 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20060058322A1 (enExample) |
| EP (1) | EP1789053B1 (enExample) |
| JP (2) | JP4929173B2 (enExample) |
| KR (1) | KR101247528B1 (enExample) |
| CN (1) | CN101043889B (enExample) |
| AU (1) | AU2005282860B2 (enExample) |
| CA (1) | CA2578702A1 (enExample) |
| DK (1) | DK1789053T3 (enExample) |
| ES (1) | ES2387653T3 (enExample) |
| HR (1) | HRP20120712T1 (enExample) |
| IL (1) | IL181634A (enExample) |
| MX (1) | MX2007002437A (enExample) |
| NO (1) | NO20071718L (enExample) |
| NZ (1) | NZ553487A (enExample) |
| PL (1) | PL1789053T3 (enExample) |
| PT (1) | PT1789053E (enExample) |
| RS (1) | RS52455B (enExample) |
| RU (1) | RU2385322C2 (enExample) |
| SI (1) | SI1789053T1 (enExample) |
| WO (1) | WO2006028810A2 (enExample) |
| ZA (1) | ZA200701777B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4769721B2 (ja) * | 2003-08-25 | 2011-09-07 | トロヴィス ファーマシューティカルズ リミテッド ライアビリティ カンパニー | 置換８−ヘテロアリールキサンチン |
| RU2391103C2 (ru) | 2004-10-15 | 2010-06-10 | Си Ви Терапьютикс, Инк. | Способ предупреждения и лечения ремоделирования дыхательных путей и воспаления легких с применением антагонистов аденозиновых рецепторов a2b |
| WO2006091936A2 (en) | 2005-02-25 | 2006-08-31 | Adenosine Therapeutics, Llc | Methods for the synthesis of unsymmetrical cycloalkyl substituted xanthines |
| WO2006091898A2 (en) * | 2005-02-25 | 2006-08-31 | Adenosine Therapeutics, Llc | Pyrazolyl substituted xanthines |
| US7579348B2 (en) * | 2005-02-25 | 2009-08-25 | Pgxhealth, Llc | Derivatives of 8-substituted xanthines |
| RU2415858C2 (ru) * | 2005-06-16 | 2011-04-10 | Си Ви Терапьютикс, Инк. | Пролекарства антагонистов a2b рецептора аденозина |
| US7884100B2 (en) * | 2006-06-16 | 2011-02-08 | Pgxhealth, Llc | Substituted 8-[6-amino-3-pyridyl]xanthines |
| US7767685B2 (en) * | 2006-06-29 | 2010-08-03 | King Pharmaceuticals Research And Development, Inc. | Adenosine A2B receptor antagonists |
| BRPI0909157A2 (pt) * | 2008-03-26 | 2015-11-24 | Advinus Therapeutics Private Ltd | compostos heterocíclicos como antagonistas de receptores de adenosina |
| US20210040097A1 (en) * | 2018-03-05 | 2021-02-11 | Teon Therapeutics, Inc. | Adenosine receptor antagonists and uses thereof |
| CN108864114B (zh) * | 2018-06-04 | 2020-11-06 | 应世生物科技(南京)有限公司 | 选择性a2a受体拮抗剂 |
| JP2023540740A (ja) * | 2020-09-04 | 2023-09-26 | テオン セラピューティクス，インク． | アデノシンａ２ｂ受容体アンタゴニストの共結晶 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4452788A (en) * | 1982-04-21 | 1984-06-05 | Warner-Lambert Company | Substituted 8-phenylxanthines |
| US4593095A (en) * | 1983-02-18 | 1986-06-03 | The Johns Hopkins University | Xanthine derivatives |
| US4558051A (en) * | 1983-10-11 | 1985-12-10 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same |
| GB8510758D0 (en) * | 1985-04-27 | 1985-06-05 | Wellcome Found | Compounds |
| DE3843117A1 (de) * | 1988-12-22 | 1990-06-28 | Boehringer Ingelheim Kg | Neue xanthinderivate mit adenosin-antagonistischer wirkung |
| DE4019892A1 (de) * | 1990-06-22 | 1992-01-02 | Boehringer Ingelheim Kg | Neue xanthinderivate |
| AU6516494A (en) * | 1993-04-15 | 1994-11-08 | New York University | Adenosine receptor agonists for the promotion of wound healing |
| US5446046A (en) * | 1993-10-28 | 1995-08-29 | University Of Florida Research Foundation | A1 adenosine receptor agonists and antagonists as diuretics |
| GB9415529D0 (en) * | 1994-08-01 | 1994-09-21 | Wellcome Found | Phenyl xanthine derivatives |
| DE19535504A1 (de) * | 1995-09-25 | 1997-03-27 | Bayer Ag | Substituierte Xanthine |
| GB9703044D0 (en) * | 1997-02-14 | 1997-04-02 | Glaxo Group Ltd | Phenyl xanthine esters and amides |
| US6117878A (en) * | 1998-02-24 | 2000-09-12 | University Of Virginia | 8-phenyl- or 8-cycloalkyl xanthine antagonists of A2B human adenosine receptors |
| US6060481A (en) * | 1998-05-28 | 2000-05-09 | The Penn State Research Foundation | Method for improving insulin sensitivity using an adenosine receptor antagonist |
| US6545002B1 (en) * | 1999-06-01 | 2003-04-08 | University Of Virginia Patent Foundation | Substituted 8-phenylxanthines useful as antagonists of A2B adenosine receptors |
| JP2003535818A (ja) * | 2000-02-17 | 2003-12-02 | スィーヴィー セラピューティクス インコーポレイテッド | 哺乳動物細胞増殖を媒介するａ２ｂアデノシンリセプタ拮抗剤の同定および使用方法 |
| US20020065286A1 (en) * | 2000-08-21 | 2002-05-30 | Davies Michael John | Treatment of wounds |
| US7490726B2 (en) * | 2001-09-06 | 2009-02-17 | Alexander Virvo | Soft toy holder |
| US6437154B1 (en) * | 2001-09-28 | 2002-08-20 | Council Of Scientific And Industrial Research | Process for the preparation of 10-deacetylbaccatin III |
| US7317017B2 (en) * | 2002-11-08 | 2008-01-08 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| PT1444233E (pt) * | 2001-11-09 | 2011-09-29 | Gilead Palo Alto Inc | Antagonistas de receptor de adenosina a2b |
| US6977300B2 (en) | 2001-11-09 | 2005-12-20 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| JP4051481B2 (ja) * | 2002-11-29 | 2008-02-27 | ヤマハマリン株式会社 | 船外機 |
| CA2528385C (en) * | 2003-06-06 | 2011-03-15 | Endacea, Inc. | A1 adenosine receptor antogonists |
| DE602004018808D1 (de) * | 2003-10-31 | 2009-02-12 | Cv Therapeutics Inc | Antagonisten des a2b-adenosinrezeptors |
-
2005
- 2005-08-30 JP JP2007530269A patent/JP4929173B2/ja not_active Expired - Lifetime
- 2005-08-30 PL PL05811901T patent/PL1789053T3/pl unknown
- 2005-08-30 CA CA002578702A patent/CA2578702A1/en not_active Abandoned
- 2005-08-30 NZ NZ553487A patent/NZ553487A/en not_active IP Right Cessation
- 2005-08-30 PT PT05811901T patent/PT1789053E/pt unknown
- 2005-08-30 RU RU2007107605/04A patent/RU2385322C2/ru active
- 2005-08-30 KR KR1020077004993A patent/KR101247528B1/ko not_active Expired - Lifetime
- 2005-08-30 SI SI200531557T patent/SI1789053T1/sl unknown
- 2005-08-30 AU AU2005282860A patent/AU2005282860B2/en not_active Expired
- 2005-08-30 CN CN2005800355648A patent/CN101043889B/zh not_active Expired - Lifetime
- 2005-08-30 EP EP05811901A patent/EP1789053B1/en not_active Expired - Lifetime
- 2005-08-30 DK DK05811901.7T patent/DK1789053T3/da active
- 2005-08-30 RS RS20120390A patent/RS52455B/sr unknown
- 2005-08-30 US US11/216,506 patent/US20060058322A1/en not_active Abandoned
- 2005-08-30 MX MX2007002437A patent/MX2007002437A/es active IP Right Grant
- 2005-08-30 ES ES05811901T patent/ES2387653T3/es not_active Expired - Lifetime
- 2005-08-30 WO PCT/US2005/030838 patent/WO2006028810A2/en not_active Ceased
- 2005-08-30 HR HRP20120712TT patent/HRP20120712T1/hr unknown
-
2007
- 2007-02-28 IL IL181634A patent/IL181634A/en active IP Right Grant
- 2007-02-28 ZA ZA200701777A patent/ZA200701777B/xx unknown
- 2007-03-30 NO NO20071718A patent/NO20071718L/no not_active Application Discontinuation
-
2011
- 2011-09-07 JP JP2011195497A patent/JP2011246492A/ja not_active Withdrawn
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