JP2008508885A5 - - Google Patents
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- JP2008508885A5 JP2008508885A5 JP2007525033A JP2007525033A JP2008508885A5 JP 2008508885 A5 JP2008508885 A5 JP 2008508885A5 JP 2007525033 A JP2007525033 A JP 2007525033A JP 2007525033 A JP2007525033 A JP 2007525033A JP 2008508885 A5 JP2008508885 A5 JP 2008508885A5
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- antibody
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- 102000008640 interleukin-21 receptor activity proteins Human genes 0.000 claims 26
- 108040002099 interleukin-21 receptor activity proteins Proteins 0.000 claims 26
- 239000012634 fragment Substances 0.000 claims 23
- 206010052779 Transplant rejections Diseases 0.000 claims 14
- 239000000427 antigen Substances 0.000 claims 13
- 102000036639 antigens Human genes 0.000 claims 12
- 108091007433 antigens Proteins 0.000 claims 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 208000035475 disorder Diseases 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 239000005557 antagonist Substances 0.000 claims 8
- 108020001507 fusion proteins Proteins 0.000 claims 6
- 102000037865 fusion proteins Human genes 0.000 claims 6
- 206010016654 Fibrosis Diseases 0.000 claims 5
- 230000004761 fibrosis Effects 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 208000027866 inflammatory disease Diseases 0.000 claims 4
- 210000000056 organ Anatomy 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 208000012657 Atopic disease Diseases 0.000 claims 3
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 claims 3
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 claims 3
- 230000002917 arthritic effect Effects 0.000 claims 3
- 208000006673 asthma Diseases 0.000 claims 3
- 210000001519 tissue Anatomy 0.000 claims 3
- 201000009961 allergic asthma Diseases 0.000 claims 2
- 208000010668 atopic eczema Diseases 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 208000023504 respiratory system disease Diseases 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 2
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 1
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 206010014954 Eosinophilic fasciitis Diseases 0.000 claims 1
- 208000005577 Gastroenteritis Diseases 0.000 claims 1
- 206010018364 Glomerulonephritis Diseases 0.000 claims 1
- 208000009329 Graft vs Host Disease Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 208000003456 Juvenile Arthritis Diseases 0.000 claims 1
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 208000003782 Raynaud disease Diseases 0.000 claims 1
- 208000012322 Raynaud phenomenon Diseases 0.000 claims 1
- 206010039085 Rhinitis allergic Diseases 0.000 claims 1
- 206010050207 Skin fibrosis Diseases 0.000 claims 1
- 201000009594 Systemic Scleroderma Diseases 0.000 claims 1
- 206010042953 Systemic sclerosis Diseases 0.000 claims 1
- 208000024780 Urticaria Diseases 0.000 claims 1
- 230000000172 allergic effect Effects 0.000 claims 1
- 201000010105 allergic rhinitis Diseases 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000037979 autoimmune inflammatory disease Diseases 0.000 claims 1
- 238000001574 biopsy Methods 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 210000000845 cartilage Anatomy 0.000 claims 1
- 208000019069 chronic childhood arthritis Diseases 0.000 claims 1
- 210000004087 cornea Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 201000001981 dermatomyositis Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000024908 graft versus host disease Diseases 0.000 claims 1
- 210000002216 heart Anatomy 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- 201000002215 juvenile rheumatoid arthritis Diseases 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
- 208000005987 polymyositis Diseases 0.000 claims 1
- 208000015768 polyposis Diseases 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59908604P | 2004-08-05 | 2004-08-05 | |
| US63917604P | 2004-12-23 | 2004-12-23 | |
| PCT/US2005/027912 WO2006135385A2 (en) | 2004-08-05 | 2005-08-05 | Antagonizing interleukin-21 receptor activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008508885A JP2008508885A (ja) | 2008-03-27 |
| JP2008508885A5 true JP2008508885A5 (https=) | 2008-09-04 |
Family
ID=37309615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007525033A Withdrawn JP2008508885A (ja) | 2004-08-05 | 2005-08-05 | インターロイキン−２１受容体活性を中和すること |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20060039902A1 (https=) |
| EP (1) | EP1773394A2 (https=) |
| JP (1) | JP2008508885A (https=) |
| KR (1) | KR20070057789A (https=) |
| AR (1) | AR051071A1 (https=) |
| AU (1) | AU2005332996A1 (https=) |
| BR (1) | BRPI0514138A (https=) |
| CA (1) | CA2574848A1 (https=) |
| CR (1) | CR8891A (https=) |
| EC (1) | ECSP077226A (https=) |
| IL (1) | IL181044A0 (https=) |
| MX (1) | MX2007001509A (https=) |
| NO (1) | NO20070973L (https=) |
| RU (1) | RU2007102287A (https=) |
| TW (1) | TW200608995A (https=) |
| WO (1) | WO2006135385A2 (https=) |
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| CA2596509A1 (en) * | 2005-02-14 | 2006-08-24 | Wyeth | Interleukin-17f antibodies and other il-17f signaling antagonists and uses therefor |
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| CN1688340A (zh) * | 2002-07-15 | 2005-10-26 | 韦思公司 | 调节t辅助(th)细胞发育和功能的方法和组合物 |
| CA2518371A1 (en) * | 2003-03-14 | 2004-09-30 | Wyeth | Antibodies against human il-21 receptor and uses therefor |
| KR20060015482A (ko) * | 2003-03-21 | 2006-02-17 | 와이어쓰 | 인터루킨-21/인터루킨-21 수용체의 작용제를 이용한면역장애의 치료 |
| US20060024268A1 (en) * | 2004-05-19 | 2006-02-02 | Wyeth | Modulation of immunoglobulin production and atopic disorders |
| GT200600148A (es) * | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis |
-
2005
- 2005-08-05 CA CA002574848A patent/CA2574848A1/en not_active Abandoned
- 2005-08-05 BR BRPI0514138-9A patent/BRPI0514138A/pt not_active IP Right Cessation
- 2005-08-05 AR ARP050103287A patent/AR051071A1/es unknown
- 2005-08-05 US US11/197,488 patent/US20060039902A1/en not_active Abandoned
- 2005-08-05 KR KR1020077002877A patent/KR20070057789A/ko not_active Withdrawn
- 2005-08-05 JP JP2007525033A patent/JP2008508885A/ja not_active Withdrawn
- 2005-08-05 AU AU2005332996A patent/AU2005332996A1/en not_active Abandoned
- 2005-08-05 EP EP05857905A patent/EP1773394A2/en not_active Withdrawn
- 2005-08-05 RU RU2007102287/13A patent/RU2007102287A/ru not_active Application Discontinuation
- 2005-08-05 MX MX2007001509A patent/MX2007001509A/es not_active Application Discontinuation
- 2005-08-05 WO PCT/US2005/027912 patent/WO2006135385A2/en not_active Ceased
- 2005-08-08 TW TW094126735A patent/TW200608995A/zh unknown
-
2007
- 2007-01-29 IL IL181044A patent/IL181044A0/en unknown
- 2007-02-01 CR CR8891A patent/CR8891A/es not_active Application Discontinuation
- 2007-02-05 EC EC2007007226A patent/ECSP077226A/es unknown
- 2007-02-21 NO NO20070973A patent/NO20070973L/no not_active Application Discontinuation
- 2007-11-29 US US11/947,425 patent/US20080241098A1/en not_active Abandoned
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