JP2008507379A5 - - Google Patents
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- Publication number
- JP2008507379A5 JP2008507379A5 JP2007523701A JP2007523701A JP2008507379A5 JP 2008507379 A5 JP2008507379 A5 JP 2008507379A5 JP 2007523701 A JP2007523701 A JP 2007523701A JP 2007523701 A JP2007523701 A JP 2007523701A JP 2008507379 A5 JP2008507379 A5 JP 2008507379A5
- Authority
- JP
- Japan
- Prior art keywords
- calcium
- phosphate
- reactant
- particle size
- particulate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000376 reactant Substances 0.000 claims 32
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 21
- 229910052791 calcium Inorganic materials 0.000 claims 21
- 239000011575 calcium Substances 0.000 claims 21
- 239000001506 calcium phosphate Substances 0.000 claims 21
- 229910019142 PO4 Inorganic materials 0.000 claims 20
- 238000000034 method Methods 0.000 claims 20
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 20
- 239000010452 phosphate Substances 0.000 claims 20
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 17
- 235000011010 calcium phosphates Nutrition 0.000 claims 17
- 239000000203 mixture Substances 0.000 claims 15
- 239000002245 particle Substances 0.000 claims 15
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 12
- -1 calcium phosphate compound Chemical class 0.000 claims 9
- 239000012530 fluid Substances 0.000 claims 9
- 230000009969 flowable effect Effects 0.000 claims 6
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims 4
- 229910000391 tricalcium phosphate Inorganic materials 0.000 claims 4
- 235000019731 tricalcium phosphate Nutrition 0.000 claims 4
- 229940078499 tricalcium phosphate Drugs 0.000 claims 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- 239000004927 clay Substances 0.000 claims 2
- 230000007547 defect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/900,029 | 2004-07-26 | ||
| US10/900,029 US7175858B2 (en) | 2004-07-26 | 2004-07-26 | Calcium phosphate cements and methods for using the same |
| PCT/US2005/026369 WO2006014886A2 (en) | 2004-07-26 | 2005-07-25 | Calcium phosphate cements and methods for using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012150927A Division JP2012192212A (ja) | 2004-07-26 | 2012-07-04 | リン酸カルシウムセメントおよびそれを使用する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008507379A JP2008507379A (ja) | 2008-03-13 |
| JP2008507379A5 true JP2008507379A5 (enExample) | 2008-07-31 |
| JP5753336B2 JP5753336B2 (ja) | 2015-07-22 |
Family
ID=35657474
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007523701A Expired - Fee Related JP5753336B2 (ja) | 2004-07-26 | 2005-07-25 | リン酸カルシウムセメントおよびそれを使用する方法 |
| JP2012150927A Pending JP2012192212A (ja) | 2004-07-26 | 2012-07-04 | リン酸カルシウムセメントおよびそれを使用する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012150927A Pending JP2012192212A (ja) | 2004-07-26 | 2012-07-04 | リン酸カルシウムセメントおよびそれを使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7175858B2 (enExample) |
| EP (1) | EP1771184B1 (enExample) |
| JP (2) | JP5753336B2 (enExample) |
| KR (1) | KR20070051845A (enExample) |
| AU (1) | AU2005269514B2 (enExample) |
| CA (1) | CA2574952C (enExample) |
| WO (1) | WO2006014886A2 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040081704A1 (en) | 1998-02-13 | 2004-04-29 | Centerpulse Biologics Inc. | Implantable putty material |
| US7820191B2 (en) * | 2000-04-28 | 2010-10-26 | Skeletal Kinetics, Llc | Calcium phosphate cements prepared from silicate solutions |
| US20020114795A1 (en) * | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
| US7166133B2 (en) * | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
| EP1615596B1 (en) * | 2003-04-11 | 2016-11-02 | Etex Corporation | Osteoinductive bone material |
| KR101218454B1 (ko) * | 2004-04-15 | 2013-01-04 | 에텍스 코포레이션 | 세팅 지연 칼슘 포스페이트 페이스트 |
| US8852240B2 (en) | 2004-10-25 | 2014-10-07 | Kieran Murphy, Llc | Methods and compositions for fostering and preserving bone growth |
| ES2402651T3 (es) | 2005-09-09 | 2013-05-07 | Agnovos Healthcare, Llc | Cemento sustituto de injerto óseo de material compuesto y artículos producidos del mismo |
| US8147860B2 (en) | 2005-12-06 | 2012-04-03 | Etex Corporation | Porous calcium phosphate bone material |
| US7718616B2 (en) * | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
| US7658940B2 (en) * | 2007-03-30 | 2010-02-09 | Skeletal Kinetics, Llc | Calcium phosphate cements comprising autologous bone |
| EP2139507A4 (en) * | 2007-04-27 | 2012-06-06 | Unigene Lab Inc | METHODS AND COMPOSITIONS FOR PROMOTING AND CONSERVING BONE GROWTH |
| US9764057B2 (en) | 2007-06-06 | 2017-09-19 | Innotere Gmbh | Hydraulic cement-based implant material and use thereof |
| JP5404407B2 (ja) * | 2007-09-20 | 2014-01-29 | 国立大学法人九州大学 | 硬化性組成物 |
| EP2358651A2 (en) | 2008-11-12 | 2011-08-24 | Engqvist, Håkan | Hydraulic cements, methods and products |
| US8409538B2 (en) | 2008-12-04 | 2013-04-02 | Skeletal Kinetics Llc | Tricalcium phosphate coarse particle compositions and methods for making the same |
| US8673364B2 (en) * | 2009-09-28 | 2014-03-18 | Skeletal Kinetics, Llc | Rapid setting high strength calcium phosphate cements comprising cyclodextrins |
| WO2010065780A1 (en) | 2008-12-04 | 2010-06-10 | Skeletal Kinetics, Llc | Tricalcium phosphate coarse particle compositions and methods for making the same |
| JP5871822B2 (ja) | 2010-03-10 | 2016-03-01 | オスディーサイン アーベー | 組織欠損を補正するためのインプラントおよび方法 |
| US20110243913A1 (en) * | 2010-04-06 | 2011-10-06 | Orthovita, Inc. | Biomaterial Compositions and Methods of Use |
| US9295695B2 (en) | 2010-04-30 | 2016-03-29 | Skeletal Kinetics, Llc | Temperature-insensitive calcium phosphate cements |
| WO2012045013A2 (en) * | 2010-10-01 | 2012-04-05 | Skeletal Kinetics, Llc | Porogen containing calcium phosphate cement compositions |
| ES2714701T3 (es) | 2010-11-10 | 2019-05-29 | Stryker European Holdings I Llc | Proceso para la preparación de una espuma ósea polimérica |
| WO2012068135A1 (en) | 2010-11-15 | 2012-05-24 | Zimmer Orthobiologics, Inc. | Bone void fillers |
| US9463046B2 (en) | 2011-08-22 | 2016-10-11 | Ossdsign Ab | Implants and methods for using such implants to fill holes in bone tissue |
| US8591645B2 (en) | 2011-09-09 | 2013-11-26 | Ossdsign Ab | Hydraulic cements with optimized grain size distribution, methods, articles and kits |
| US20130066327A1 (en) | 2011-09-09 | 2013-03-14 | Håkan Engqvist | Hydraulic cement compositions with low ph methods, articles and kits |
| US10207027B2 (en) | 2012-06-11 | 2019-02-19 | Globus Medical, Inc. | Bioactive bone graft substitutes |
| EP2931325B1 (en) | 2012-12-14 | 2020-02-19 | OssDsign AB | Cement-forming compositions, monetite cements, implants and methods for correcting bone defects |
| HK1217632A1 (zh) | 2013-02-12 | 2017-01-20 | Ossdsign Ab | 镶嵌型植人物、试剂盒和用於矫正骨缺损的方法 |
| US9220597B2 (en) | 2013-02-12 | 2015-12-29 | Ossdsign Ab | Mosaic implants, kits and methods for correcting bone defects |
| US9539286B2 (en) | 2013-10-18 | 2017-01-10 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
| US9486483B2 (en) | 2013-10-18 | 2016-11-08 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
| US9579421B2 (en) | 2014-02-07 | 2017-02-28 | Globus Medical Inc. | Bone grafts and methods of making and using bone grafts |
| US9463264B2 (en) | 2014-02-11 | 2016-10-11 | Globus Medical, Inc. | Bone grafts and methods of making and using bone grafts |
| KR20170043110A (ko) | 2014-08-14 | 2017-04-20 | 오에스에스디자인 아베 | 뼈 결함 교정을 위한 뼈 이식 |
| US11426489B2 (en) | 2015-06-10 | 2022-08-30 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
| US10016529B2 (en) | 2015-06-10 | 2018-07-10 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
| CN112969422B (zh) | 2018-10-16 | 2024-07-12 | 奥斯设计公司 | 用于填充骨中钻孔的植入物和用于填充骨中钻孔的方法 |
| US11896736B2 (en) | 2020-07-13 | 2024-02-13 | Globus Medical, Inc | Biomaterial implants and methods of making the same |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5370097A (en) | 1976-12-03 | 1978-06-22 | Central Glass Co Ltd | Purifying method for crude sodium silicofluoride |
| JPS5395196A (en) | 1977-02-01 | 1978-08-19 | Central Glass Co Ltd | Production of purified sodium silicofluoride |
| JPS5654841A (en) | 1979-10-08 | 1981-05-15 | Mitsubishi Mining & Cement Co | Bone broken portion and filler for void portion and method of treating bone of animal using said filler |
| US4718910A (en) * | 1985-07-16 | 1988-01-12 | Klaus Draenert | Bone cement and process for preparing the same |
| US5962028A (en) | 1988-04-20 | 1999-10-05 | Norian Corporation | Carbonated hydroxyapatite compositions and uses |
| US6005162A (en) | 1988-04-20 | 1999-12-21 | Norian Corporation | Methods of repairing bone |
| US4990163A (en) | 1989-02-06 | 1991-02-05 | Trustees Of The University Of Pennsylvania | Method of depositing calcium phosphate cermamics for bone tissue calcification enhancement |
| US5281265A (en) | 1992-02-03 | 1994-01-25 | Liu Sung Tsuen | Resorbable surgical cements |
| ATE140723T1 (de) * | 1992-12-11 | 1996-08-15 | Quest Int | Demethyl-cyclohexanecarbonsäureestern in der parfümerie |
| US5522893A (en) | 1993-03-12 | 1996-06-04 | American Dental Association Health Foundation | Calcium phosphate hydroxyapatite precursor and methods for making and using the same |
| EP0710267A4 (en) | 1993-07-22 | 1996-07-10 | Norian Corp | PARTIALLY NEUTRALIZED ACID COMPOSITIONS STABLE DURING STORAGE AND USES THEREOF |
| US5525148A (en) | 1993-09-24 | 1996-06-11 | American Dental Association Health Foundation | Self-setting calcium phosphate cements and methods for preparing and using them |
| CA2143733A1 (en) | 1994-03-02 | 1995-09-03 | Yoshikazu Umezu | Alpha-tricalcium phosphate ceramic and production method thereof |
| US6586006B2 (en) * | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
| US5496399A (en) | 1994-08-23 | 1996-03-05 | Norian Corporation | Storage stable calcium phosphate cements |
| US5569442A (en) * | 1994-11-04 | 1996-10-29 | Norian Corporation | Reactive tricalcium phosphate compositions and uses |
| US6027742A (en) | 1995-05-19 | 2000-02-22 | Etex Corporation | Bioresorbable ceramic composites |
| US6132463A (en) | 1995-05-19 | 2000-10-17 | Etex Corporation | Cell seeding of ceramic compositions |
| US5795922A (en) * | 1995-06-06 | 1998-08-18 | Clemson University | Bone cement composistion containing microencapsulated radiopacifier and method of making same |
| ZA9711732B (en) * | 1996-12-31 | 1998-12-28 | Quadrant Holdings Cambridge | Methods and compositions for improvement bioavailability of bioactive agents for mucosal delivery |
| US20020009464A1 (en) * | 1997-07-03 | 2002-01-24 | Camilo Colaco | Modified glycosides, compositions comprised thereof and methods of use thereof |
| JP2001518359A (ja) * | 1997-10-07 | 2001-10-16 | ドクトル．ハー．ツェー．ロベルト マシーズ スティフツング | 外科用水硬セメント |
| US6352722B1 (en) * | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
| DE19812713A1 (de) * | 1998-03-24 | 1999-09-30 | Merck Patent Gmbh | Verfahren zur Herstellung von mineralisierten Kollagenfibrillen und deren Verwendung als Knochenersatzwerkstoff |
| US6730322B1 (en) * | 1998-04-30 | 2004-05-04 | Acusphere, Inc. | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
| US5968253A (en) | 1998-07-31 | 1999-10-19 | Norian Corporation | Calcium phosphate cements comprising antimicrobial agents |
| JP2001106638A (ja) * | 1999-08-05 | 2001-04-17 | Takeda Chem Ind Ltd | 骨形成促進物質徐放性ペースト |
| ATE245456T1 (de) * | 1999-12-09 | 2003-08-15 | Robert Mathys Stiftung | Mit einem magnesiumsalz stabilisierter hydraulischer brushitzement |
| FR2805747B1 (fr) * | 2000-03-01 | 2003-03-14 | Teknimed | Procede de preparation d'un materiau pateux phosphocalcique injectable en vue de former un biomateriau apatitique et application chirurgicale ou dentaire |
| US6375935B1 (en) | 2000-04-28 | 2002-04-23 | Brent R. Constantz | Calcium phosphate cements prepared from silicate solutions |
| US6547866B1 (en) | 2000-10-30 | 2003-04-15 | Howmedica Osteonics Corp. | Porous calcium phosphate cement |
| US6840961B2 (en) | 2001-12-21 | 2005-01-11 | Etex Corporation | Machinable preformed calcium phosphate bone substitute material implants |
| CA2609772A1 (en) | 2005-06-07 | 2006-12-14 | The Lutheran University Association, Inc, D/B/A Valparaiso University | Quantum-dot cellular automata methods and devices |
-
2004
- 2004-07-26 US US10/900,029 patent/US7175858B2/en not_active Expired - Lifetime
-
2005
- 2005-07-25 AU AU2005269514A patent/AU2005269514B2/en not_active Ceased
- 2005-07-25 KR KR1020077002081A patent/KR20070051845A/ko not_active Abandoned
- 2005-07-25 CA CA2574952A patent/CA2574952C/en not_active Expired - Fee Related
- 2005-07-25 EP EP05781881.7A patent/EP1771184B1/en not_active Expired - Lifetime
- 2005-07-25 US US11/189,555 patent/US8419803B2/en not_active Expired - Fee Related
- 2005-07-25 JP JP2007523701A patent/JP5753336B2/ja not_active Expired - Fee Related
- 2005-07-25 WO PCT/US2005/026369 patent/WO2006014886A2/en not_active Ceased
-
2012
- 2012-07-04 JP JP2012150927A patent/JP2012192212A/ja active Pending
-
2013
- 2013-03-13 US US13/800,694 patent/US10022471B2/en active Active
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