JP2008504257A5 - - Google Patents
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- Publication number
- JP2008504257A5 JP2008504257A5 JP2007518098A JP2007518098A JP2008504257A5 JP 2008504257 A5 JP2008504257 A5 JP 2008504257A5 JP 2007518098 A JP2007518098 A JP 2007518098A JP 2007518098 A JP2007518098 A JP 2007518098A JP 2008504257 A5 JP2008504257 A5 JP 2008504257A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- pharmaceutically acceptable
- related macular
- macular degeneration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 14
- 208000011325 dry age related macular degeneration Diseases 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- AKJHMTWEGVYYSE-AIRMAKDCSA-N 4-HPR Chemical compound C=1C=C(O)C=CC=1NC(=O)/C=C(\C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C AKJHMTWEGVYYSE-AIRMAKDCSA-N 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- RYCNUMLMNKHWPZ-SNVBAGLBSA-N 1-acetyl-sn-glycero-3-phosphocholine Chemical compound CC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C RYCNUMLMNKHWPZ-SNVBAGLBSA-N 0.000 claims 1
- 241000208140 Acer Species 0.000 claims 1
- 206010003694 Atrophy Diseases 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 230000037444 atrophy Effects 0.000 claims 1
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000002285 corn oil Substances 0.000 claims 1
- 235000005687 corn oil Nutrition 0.000 claims 1
- 230000007850 degeneration Effects 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 239000008298 dragée Substances 0.000 claims 1
- -1 elixir Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 108091008695 photoreceptors Proteins 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000002002 slurry Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 239000000080 wetting agent Substances 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58229304P | 2004-06-23 | 2004-06-23 | |
| US60/582,293 | 2004-06-23 | ||
| US62969504P | 2004-11-19 | 2004-11-19 | |
| US60/629,695 | 2004-11-19 | ||
| US66090405P | 2005-03-11 | 2005-03-11 | |
| US60/660,904 | 2005-03-11 | ||
| US67240505P | 2005-04-18 | 2005-04-18 | |
| US60/672,405 | 2005-04-18 | ||
| PCT/US2005/020080 WO2006007314A1 (en) | 2004-06-23 | 2005-06-06 | Methods and compositions for treating ophthalmic conditions with retinyl derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008504257A JP2008504257A (ja) | 2008-02-14 |
| JP2008504257A5 true JP2008504257A5 (enExample) | 2008-07-10 |
| JP4855396B2 JP4855396B2 (ja) | 2012-01-18 |
Family
ID=34981643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007518098A Expired - Fee Related JP4855396B2 (ja) | 2004-06-23 | 2005-06-06 | レチナール誘導体で眼科的な状態を処置するための方法および組成物 |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US8314152B2 (enExample) |
| EP (3) | EP1768657B1 (enExample) |
| JP (1) | JP4855396B2 (enExample) |
| KR (1) | KR100862930B1 (enExample) |
| AR (1) | AR049929A1 (enExample) |
| AT (1) | ATE404188T1 (enExample) |
| AU (1) | AU2005262558B8 (enExample) |
| BR (1) | BRPI0512569A (enExample) |
| CA (1) | CA2569691C (enExample) |
| CY (1) | CY1110435T1 (enExample) |
| DE (1) | DE602005008970D1 (enExample) |
| DK (1) | DK1768657T3 (enExample) |
| EA (1) | EA011864B1 (enExample) |
| ES (1) | ES2313368T3 (enExample) |
| GE (1) | GEP20084520B (enExample) |
| IL (1) | IL179872A (enExample) |
| LV (1) | LV13564B (enExample) |
| MX (1) | MXPA06014978A (enExample) |
| NO (1) | NO20070408L (enExample) |
| NZ (1) | NZ551955A (enExample) |
| PL (1) | PL1768657T3 (enExample) |
| PT (1) | PT1768657E (enExample) |
| SG (1) | SG140607A1 (enExample) |
| SI (1) | SI1768657T1 (enExample) |
| TW (1) | TWI396532B (enExample) |
| WO (1) | WO2006007314A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060281821A1 (en) | 2003-03-14 | 2006-12-14 | Krzysztof Palczewski | Retinoid replacements and opsin agonists and methods for the use thereof |
| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| WO2005079774A2 (en) | 2004-02-17 | 2005-09-01 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| JP2007525496A (ja) * | 2004-02-17 | 2007-09-06 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 黄班変性症を含む眼科疾患の管理 |
| AU2005257997B2 (en) | 2004-06-18 | 2012-04-05 | University Of Washington | Retinal derivatives and methods for the use thereof for the treatment of visual disorders |
| KR100862930B1 (ko) | 2004-06-23 | 2008-10-13 | 시리온 테라퓨틱스, 인크. | 레티닐 유도체를 사용하여 안 증상을 치료하기 위한 방법및 조성물 |
| US20060089411A1 (en) * | 2004-08-07 | 2006-04-27 | Gierhart Dennis L | Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin |
| AU2005287343A1 (en) * | 2004-08-18 | 2006-03-30 | Sirion Therapeutics, Inc. | Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders |
| JP5144267B2 (ja) * | 2004-10-28 | 2013-02-13 | アイデックス ラボラトリーズ,インコーポレイティド | 医薬活性化合物を制御して搬送するための組成物 |
| WO2006052860A2 (en) * | 2004-11-04 | 2006-05-18 | Sirion Therapeutics, Inc. | Modulators of retinol-retinol binding protein (rbp)-transthyretin (ttr) complex formation |
| EP1930046A1 (en) * | 2004-12-08 | 2008-06-11 | Sirion Therapeutics, Inc. | Retinol binding protein and transthyretin modulators for treating diabetes |
| UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
| US7754679B2 (en) * | 2005-11-16 | 2010-07-13 | Idexx Laboratories, Inc. | Pharmaceutical compositions for the administration of aptamers |
| US8114440B2 (en) * | 2005-11-16 | 2012-02-14 | Idexx Laboratories Inc. | Pharmaceutical compositions for the administration of aptamers |
| AU2007260872A1 (en) * | 2006-06-22 | 2007-12-27 | Sirion Therapeutics, Inc | Methods and compositions for treating ophthalmic conditions via modulation of megalin activity |
| WO2008013986A2 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for treating or preventing ophthalmic light toxicity |
| EP2069391A4 (en) * | 2006-07-27 | 2009-12-30 | Univ Florida | COMPOSITIONS AND METHODS FOR TREATING AND / OR PREVENTING OPHTHALMOLOGICAL DISEASES |
| AU2007277032A1 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Opsin stabilizing compounds and methods of use |
| US8828960B2 (en) * | 2007-07-17 | 2014-09-09 | Idexx Laboratories, Inc. | Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds |
| US8324270B2 (en) * | 2008-02-11 | 2012-12-04 | University Of Washington | Methods for the treatment and prevention of age-related retinal dysfunction |
| WO2009114136A2 (en) * | 2008-03-12 | 2009-09-17 | Albert Einstein College Of Medicine Of Yeshiva University | Fenretinide derivatives and uses thereof as therapeutic, diagnostic and imaging agents |
| EP2296632A4 (en) * | 2008-07-14 | 2014-11-12 | Otonomy Inc | COMPOSITIONS AND METHODS FOR MODULATING CONTROLLED RELEASE APOPTOSIS FOR THE TREATMENT OF OTIC DISORDERS |
| EP2427052B1 (en) * | 2009-05-04 | 2015-08-26 | Acucela, Inc. | Compositions for use in the treatment of glaucoma or ocular hypertension |
| IN2012DN00352A (enExample) | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
| RU2546005C2 (ru) | 2009-09-15 | 2015-04-10 | Кью Эл Ти ИНК. | Фармацевтические составы, содержащие 9-цис-ретиниловые сложные эфиры в липидном наполнителе |
| WO2011071995A2 (en) | 2009-12-08 | 2011-06-16 | Case Western Reserve University | Compounds and methods of treating ocular disorders |
| SG10201507819VA (en) * | 2010-04-19 | 2015-10-29 | Quadra Logic Tech Inc | Therapeutic Regimen And Methods For Treating Or Ameliorating Visual Disorders Associated With An Endogenous Retinoid Deficiency |
| CA2862807A1 (en) | 2011-11-30 | 2013-06-06 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
| AU2013216861B2 (en) * | 2012-02-10 | 2017-05-18 | Tlc Biopharmaceuticals, Inc | Pharmaceutical compositions to reduce complications of ocular steroid |
| AU2013232697B2 (en) | 2012-03-01 | 2017-10-19 | Eluminex Biosciences (Suzhou) Limited | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
| US9011845B2 (en) | 2012-06-26 | 2015-04-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods for treatment of inflammatory and infectious viral diseases |
| US8877183B2 (en) | 2012-06-26 | 2014-11-04 | National Institutes Of Health (Nih) | Methods for treatment of ocular diseases |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| US10092393B2 (en) | 2013-03-14 | 2018-10-09 | Allotex, Inc. | Corneal implant systems and methods |
| US10471118B2 (en) * | 2014-05-30 | 2019-11-12 | Case Western Reserve University | Retinylamine derivitives for treatment of ocular disorders |
| JP6588027B2 (ja) | 2014-10-24 | 2019-10-09 | 武田薬品工業株式会社 | 複素環化合物 |
| US10327946B2 (en) * | 2014-12-19 | 2019-06-25 | Kemin Industries, Inc. | Intraocular delivery of bioactive molecules using iontophoresis |
| US10449090B2 (en) | 2015-07-31 | 2019-10-22 | Allotex, Inc. | Corneal implant systems and methods |
| RU2718065C2 (ru) * | 2016-02-15 | 2020-03-30 | Кемин Индастриз, Инк. | Положительно заряженные липосомы в качестве липофильных молекул-носителей |
| US11395853B2 (en) * | 2016-06-23 | 2022-07-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomimetic drug delivery of an immunomodulatory agent for the treatment of ocular conditions |
| US11369695B2 (en) | 2016-12-05 | 2022-06-28 | The Jackson Laboratory | Fat droplets in retina and optic nerve as a diagnostic marker for neurodegeneration and glaucoma in humans |
| TW201906635A (zh) * | 2017-07-04 | 2019-02-16 | 日商第一三共股份有限公司 | 伴隨視細胞變性的視網膜變性的疾病用藥 |
| CA3137034A1 (en) * | 2019-05-06 | 2020-11-12 | Howard J. Federoff | Materials and methods for treating age-related macular degeneration |
| FR3105790B1 (fr) * | 2019-12-26 | 2022-01-14 | Biophytis | Composés chimiques ciblant l’œil et leur utilisation dans le traitement de maladies oculaires |
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| WO2005077176A1 (en) | 2004-02-11 | 2005-08-25 | The Trustees Of Columbia University In The City Of New York | Anthocyanin compounds and methods of use thereof |
| WO2005079774A2 (en) * | 2004-02-17 | 2005-09-01 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| CN1964706A (zh) | 2004-03-17 | 2007-05-16 | 拉斯·M·拉森 | 通过抑制视觉周期预防视网膜病 |
| AU2005257997B2 (en) | 2004-06-18 | 2012-04-05 | University Of Washington | Retinal derivatives and methods for the use thereof for the treatment of visual disorders |
| KR100862930B1 (ko) | 2004-06-23 | 2008-10-13 | 시리온 테라퓨틱스, 인크. | 레티닐 유도체를 사용하여 안 증상을 치료하기 위한 방법및 조성물 |
| US7286860B2 (en) | 2004-07-23 | 2007-10-23 | Dyna Llc | Systems and methods for a comfortable wireless communication device |
| AU2005287343A1 (en) | 2004-08-18 | 2006-03-30 | Sirion Therapeutics, Inc. | Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders |
| WO2006052860A2 (en) | 2004-11-04 | 2006-05-18 | Sirion Therapeutics, Inc. | Modulators of retinol-retinol binding protein (rbp)-transthyretin (ttr) complex formation |
| EP1930046A1 (en) | 2004-12-08 | 2008-06-11 | Sirion Therapeutics, Inc. | Retinol binding protein and transthyretin modulators for treating diabetes |
| UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding |
-
2005
- 2005-06-06 KR KR1020077001270A patent/KR100862930B1/ko not_active Expired - Fee Related
- 2005-06-06 JP JP2007518098A patent/JP4855396B2/ja not_active Expired - Fee Related
- 2005-06-06 DK DK05758777T patent/DK1768657T3/da active
- 2005-06-06 CA CA2569691A patent/CA2569691C/en not_active Expired - Fee Related
- 2005-06-06 AT AT05758777T patent/ATE404188T1/de active
- 2005-06-06 WO PCT/US2005/020080 patent/WO2006007314A1/en not_active Ceased
- 2005-06-06 NZ NZ551955A patent/NZ551955A/en not_active IP Right Cessation
- 2005-06-06 EP EP05758777A patent/EP1768657B1/en not_active Expired - Lifetime
- 2005-06-06 PL PL05758777T patent/PL1768657T3/pl unknown
- 2005-06-06 BR BRPI0512569-3A patent/BRPI0512569A/pt not_active IP Right Cessation
- 2005-06-06 GE GEAP20059816A patent/GEP20084520B/en unknown
- 2005-06-06 EA EA200700109A patent/EA011864B1/ru not_active IP Right Cessation
- 2005-06-06 DE DE602005008970T patent/DE602005008970D1/de not_active Expired - Lifetime
- 2005-06-06 EP EP08014275A patent/EP2025336A1/en not_active Withdrawn
- 2005-06-06 SG SG200801546-3A patent/SG140607A1/en unknown
- 2005-06-06 ES ES05758777T patent/ES2313368T3/es not_active Expired - Lifetime
- 2005-06-06 MX MXPA06014978A patent/MXPA06014978A/es active IP Right Grant
- 2005-06-06 EP EP10181656A patent/EP2277516A1/en not_active Withdrawn
- 2005-06-06 SI SI200530415T patent/SI1768657T1/sl unknown
- 2005-06-06 PT PT05758777T patent/PT1768657E/pt unknown
- 2005-06-06 AU AU2005262558A patent/AU2005262558B8/en not_active Ceased
- 2005-06-10 US US11/150,641 patent/US8314152B2/en not_active Expired - Fee Related
- 2005-06-21 AR ARP050102545A patent/AR049929A1/es not_active Application Discontinuation
- 2005-06-22 TW TW094120880A patent/TWI396532B/zh not_active IP Right Cessation
-
2006
- 2006-12-06 IL IL179872A patent/IL179872A/en not_active IP Right Cessation
-
2007
- 2007-01-19 LV LVP-07-05A patent/LV13564B/lv unknown
- 2007-01-22 NO NO20070408A patent/NO20070408L/no not_active Application Discontinuation
-
2008
- 2008-11-12 CY CY20081101287T patent/CY1110435T1/el unknown
-
2010
- 2010-04-21 US US12/764,764 patent/US8410168B2/en not_active Expired - Fee Related
-
2011
- 2011-05-27 US US13/118,330 patent/US20110294891A1/en not_active Abandoned
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