DE602005008970D1 - Verfahren und zusammensetzungen zur behandlung von augenerkrankungen mit retinyl-derivaten - Google Patents
Verfahren und zusammensetzungen zur behandlung von augenerkrankungen mit retinyl-derivatenInfo
- Publication number
- DE602005008970D1 DE602005008970D1 DE602005008970T DE602005008970T DE602005008970D1 DE 602005008970 D1 DE602005008970 D1 DE 602005008970D1 DE 602005008970 T DE602005008970 T DE 602005008970T DE 602005008970 T DE602005008970 T DE 602005008970T DE 602005008970 D1 DE602005008970 D1 DE 602005008970D1
- Authority
- DE
- Germany
- Prior art keywords
- compositions
- eye diseases
- treating eye
- retinyl derivatives
- retinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/16—Ophthalmology
- G01N2800/164—Retinal disorders, e.g. retinopathy
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58229304P | 2004-06-23 | 2004-06-23 | |
US62969504P | 2004-11-19 | 2004-11-19 | |
US66090405P | 2005-03-11 | 2005-03-11 | |
US67240505P | 2005-04-18 | 2005-04-18 | |
PCT/US2005/020080 WO2006007314A1 (en) | 2004-06-23 | 2005-06-06 | Methods and compositions for treating ophthalmic conditions with retinyl derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005008970D1 true DE602005008970D1 (de) | 2008-09-25 |
Family
ID=34981643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005008970T Active DE602005008970D1 (de) | 2004-06-23 | 2005-06-06 | Verfahren und zusammensetzungen zur behandlung von augenerkrankungen mit retinyl-derivaten |
Country Status (27)
Country | Link |
---|---|
US (3) | US8314152B2 (de) |
EP (3) | EP2277516A1 (de) |
JP (1) | JP4855396B2 (de) |
KR (1) | KR100862930B1 (de) |
AR (1) | AR049929A1 (de) |
AT (1) | ATE404188T1 (de) |
AU (1) | AU2005262558B8 (de) |
BR (1) | BRPI0512569A (de) |
CA (1) | CA2569691C (de) |
CY (1) | CY1110435T1 (de) |
DE (1) | DE602005008970D1 (de) |
DK (1) | DK1768657T3 (de) |
EA (1) | EA011864B1 (de) |
ES (1) | ES2313368T3 (de) |
GE (1) | GEP20084520B (de) |
HK (1) | HK1107671A1 (de) |
IL (1) | IL179872A (de) |
LV (1) | LV13564B (de) |
MX (1) | MXPA06014978A (de) |
NO (1) | NO20070408L (de) |
NZ (1) | NZ551955A (de) |
PL (1) | PL1768657T3 (de) |
PT (1) | PT1768657E (de) |
SG (1) | SG140607A1 (de) |
SI (1) | SI1768657T1 (de) |
TW (1) | TWI396532B (de) |
WO (1) | WO2006007314A1 (de) |
Families Citing this family (44)
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EP1610772A4 (de) | 2003-03-14 | 2008-06-18 | Univ Washington | Retinoid-ersatz und opsin-agonisten und anwendungsverfahren dafür |
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US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
BRPI0507807A (pt) | 2004-02-17 | 2007-07-31 | Harvard College | gerenciamento de distúrbios oftalmológicos, incluindo degeneração macular |
KR101337321B1 (ko) | 2004-06-18 | 2013-12-06 | 유니버시티 오브 워싱톤 | 시각 이상 치료를 위한 레티날 유도체 및 이를 이용하기위한 방법 |
AU2005262558B8 (en) | 2004-06-23 | 2008-04-10 | Revision Therapeutics, Inc. | Methods and compositions for treating ophthalmic conditions with retinyl derivatives |
US20060089411A1 (en) * | 2004-08-07 | 2006-04-27 | Gierhart Dennis L | Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin |
JP2008515778A (ja) * | 2004-08-18 | 2008-05-15 | シリオン セラピューティクス, インコーポレイテッド | 眼の状態を13−シス−レチニル誘導体で処置するための組み合わせ方法、組成物および治療 |
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EP1807103A4 (de) * | 2004-11-04 | 2009-02-11 | Sirion Therapeutics Inc | Modulatoren einer komplexen retinol-retinol-bindenden protein-transthyretin-formation |
EA011154B1 (ru) * | 2004-12-08 | 2009-02-27 | Сирион Терапьютикс, Инк. | Композиции для лечения ретинол-ассоциированных заболеваний |
UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
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AU2007277033A1 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for treating or preventing ophthalmic disease |
WO2008013983A2 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Opsin stabilizing compounds and methods of use |
WO2008013986A2 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for treating or preventing ophthalmic light toxicity |
US8828960B2 (en) * | 2007-07-17 | 2014-09-09 | Idexx Laboratories, Inc. | Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds |
KR101810381B1 (ko) * | 2008-02-11 | 2017-12-19 | 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 | 연령-관련 망막 기능장애의 치료 및 예방 방법 |
US8460635B2 (en) * | 2008-03-12 | 2013-06-11 | Albert Einstein College Of Medicine Of Yeshiva University | Fenretinide derivatives and uses thereof as therapeutic, diagnostic and imaging agents |
AU2009271129B2 (en) * | 2008-07-14 | 2013-10-10 | Otonomy, Inc. | Controlled-release apoptosis modulating compositions and methods for the treatment of otic disorders |
EP2427052B1 (de) * | 2009-05-04 | 2015-08-26 | Acucela, Inc. | Zusammensetzungen zur verwendung in der behandlung von glaukom oder augenhochdruck |
IN2012DN00352A (de) | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
RU2546005C2 (ru) | 2009-09-15 | 2015-04-10 | Кью Эл Ти ИНК. | Фармацевтические составы, содержащие 9-цис-ретиниловые сложные эфиры в липидном наполнителе |
WO2011071995A2 (en) | 2009-12-08 | 2011-06-16 | Case Western Reserve University | Compounds and methods of treating ocular disorders |
JP6250389B2 (ja) | 2010-04-19 | 2017-12-20 | ノベリオン セラピューティクス インコーポレイテッド | 内因性レチノイド欠損に関連する視覚障害を治療する又は改善する治療計画及び治療方法 |
JP6126118B2 (ja) | 2011-11-30 | 2017-05-10 | ビカム ファーマスーティカルス,インコーポレイテッド | オプシン結合性リガンド、組成物、及び使用方法 |
TWI620578B (zh) * | 2012-02-10 | 2018-04-11 | 台灣微脂體股份有限公司 | 用以減少眼用類固醇的倂發症之藥學組成物 |
KR102133608B1 (ko) | 2012-03-01 | 2020-07-13 | 레티나제닉스, 엘엘씨 | 내인성 레티노이드 결핍증과 관련된 시각 장애에서 시각 기능의 개선을 위한 치료 요법 및 방법 |
US9011845B2 (en) | 2012-06-26 | 2015-04-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods for treatment of inflammatory and infectious viral diseases |
WO2014003850A2 (en) | 2012-06-26 | 2014-01-03 | Timothy Paul Foster | Methods for treatment of ocular diseases |
US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
US10092393B2 (en) | 2013-03-14 | 2018-10-09 | Allotex, Inc. | Corneal implant systems and methods |
WO2015184453A1 (en) * | 2014-05-30 | 2015-12-03 | Case Western Reserve University | Retinylamine derivitives for treatment of ocular disorders |
MY183209A (en) | 2014-10-24 | 2021-02-18 | Takeda Pharmaceuticals Co | Heterocyclic compound |
CN107249678B (zh) * | 2014-12-19 | 2021-02-19 | 凯敏工业公司 | 使用离子电渗法进行生物活性分子的眼内递送 |
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PT3416622T (pt) * | 2016-02-15 | 2023-08-28 | Kemin Ind Inc | Lipossomas com carga positiva como transportadores de moléculas lipofílicas |
US11395853B2 (en) * | 2016-06-23 | 2022-07-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomimetic drug delivery of an immunomodulatory agent for the treatment of ocular conditions |
US11369695B2 (en) | 2016-12-05 | 2022-06-28 | The Jackson Laboratory | Fat droplets in retina and optic nerve as a diagnostic marker for neurodegeneration and glaucoma in humans |
TW201906635A (zh) * | 2017-07-04 | 2019-02-16 | 日商第一三共股份有限公司 | 伴隨視細胞變性的視網膜變性的疾病用藥 |
BR112021022270A2 (pt) * | 2019-05-06 | 2022-01-11 | Univ California | Materiais e métodos para tratar degeneração macular relacionada à idade |
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-
2005
- 2005-06-06 AU AU2005262558A patent/AU2005262558B8/en not_active Ceased
- 2005-06-06 NZ NZ551955A patent/NZ551955A/en not_active IP Right Cessation
- 2005-06-06 EA EA200700109A patent/EA011864B1/ru not_active IP Right Cessation
- 2005-06-06 ES ES05758777T patent/ES2313368T3/es active Active
- 2005-06-06 CA CA2569691A patent/CA2569691C/en not_active Expired - Fee Related
- 2005-06-06 BR BRPI0512569-3A patent/BRPI0512569A/pt not_active IP Right Cessation
- 2005-06-06 PL PL05758777T patent/PL1768657T3/pl unknown
- 2005-06-06 DK DK05758777T patent/DK1768657T3/da active
- 2005-06-06 EP EP10181656A patent/EP2277516A1/de not_active Withdrawn
- 2005-06-06 PT PT05758777T patent/PT1768657E/pt unknown
- 2005-06-06 DE DE602005008970T patent/DE602005008970D1/de active Active
- 2005-06-06 AT AT05758777T patent/ATE404188T1/de active
- 2005-06-06 JP JP2007518098A patent/JP4855396B2/ja not_active Expired - Fee Related
- 2005-06-06 SG SG200801546-3A patent/SG140607A1/en unknown
- 2005-06-06 EP EP05758777A patent/EP1768657B1/de not_active Not-in-force
- 2005-06-06 GE GEAP20059816A patent/GEP20084520B/en unknown
- 2005-06-06 EP EP08014275A patent/EP2025336A1/de not_active Withdrawn
- 2005-06-06 KR KR1020077001270A patent/KR100862930B1/ko not_active IP Right Cessation
- 2005-06-06 SI SI200530415T patent/SI1768657T1/sl unknown
- 2005-06-06 WO PCT/US2005/020080 patent/WO2006007314A1/en active Application Filing
- 2005-06-06 MX MXPA06014978A patent/MXPA06014978A/es active IP Right Grant
- 2005-06-10 US US11/150,641 patent/US8314152B2/en not_active Expired - Fee Related
- 2005-06-21 AR ARP050102545A patent/AR049929A1/es not_active Application Discontinuation
- 2005-06-22 TW TW094120880A patent/TWI396532B/zh not_active IP Right Cessation
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2006
- 2006-12-06 IL IL179872A patent/IL179872A/en not_active IP Right Cessation
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2007
- 2007-01-19 LV LVP-07-05A patent/LV13564B/lv unknown
- 2007-01-22 NO NO20070408A patent/NO20070408L/no not_active Application Discontinuation
- 2007-12-06 HK HK07113340.3A patent/HK1107671A1/xx not_active IP Right Cessation
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2008
- 2008-11-12 CY CY20081101287T patent/CY1110435T1/el unknown
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2010
- 2010-04-21 US US12/764,764 patent/US8410168B2/en not_active Expired - Fee Related
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2011
- 2011-05-27 US US13/118,330 patent/US20110294891A1/en not_active Abandoned
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