JP2008502332A5 - - Google Patents

Download PDF

Info

Publication number
JP2008502332A5
JP2008502332A5 JP2007515787A JP2007515787A JP2008502332A5 JP 2008502332 A5 JP2008502332 A5 JP 2008502332A5 JP 2007515787 A JP2007515787 A JP 2007515787A JP 2007515787 A JP2007515787 A JP 2007515787A JP 2008502332 A5 JP2008502332 A5 JP 2008502332A5
Authority
JP
Japan
Prior art keywords
nucleic acid
sample
methylated
acid fragments
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007515787A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008502332A (ja
Filing date
Publication date
Priority claimed from GBGB0413688.3A external-priority patent/GB0413688D0/en
Application filed filed Critical
Publication of JP2008502332A publication Critical patent/JP2008502332A/ja
Publication of JP2008502332A5 publication Critical patent/JP2008502332A5/ja
Pending legal-status Critical Current

Links

JP2007515787A 2004-06-18 2005-03-03 メチル化核酸の分析 Pending JP2008502332A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0413688.3A GB0413688D0 (en) 2004-06-18 2004-06-18 Analysis of methylated nucleic acid
PCT/EP2005/002251 WO2005123942A2 (en) 2004-06-18 2005-03-03 Analysis of methylated nucleic acid

Publications (2)

Publication Number Publication Date
JP2008502332A JP2008502332A (ja) 2008-01-31
JP2008502332A5 true JP2008502332A5 (https=) 2008-04-17

Family

ID=32750180

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007515787A Pending JP2008502332A (ja) 2004-06-18 2005-03-03 メチル化核酸の分析

Country Status (8)

Country Link
US (2) US20090270482A1 (https=)
EP (1) EP1761639B1 (https=)
JP (1) JP2008502332A (https=)
AU (2) AU2005254616A1 (https=)
CA (1) CA2568575A1 (https=)
ES (1) ES2401110T3 (https=)
GB (1) GB0413688D0 (https=)
WO (1) WO2005123942A2 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005034628B4 (de) * 2005-07-19 2007-08-23 Epigenomics Ag Verfahren zur Untersuchung von Cytosin-Methylierungen in DNA
EP1862555A1 (en) * 2006-05-29 2007-12-05 Klinikum der Universität Regensburg Means and methods for diagnosing cancer or a corresponding predisposition
US20120196827A1 (en) * 2006-06-12 2012-08-02 Oncomethylome Sciences S.A. Methylation markers for early detection and prognosis of colon cancers
AU2008316313B2 (en) * 2007-10-23 2015-04-16 Clinical Genomics Pty. Ltd. A method of diagnosing neoplasms - II
JP2009247260A (ja) * 2008-04-04 2009-10-29 Sumitomo Chemical Co Ltd Dnaメチル化測定方法
KR101636596B1 (ko) * 2009-04-17 2016-07-11 내셔널 디펜스 메디컬 센터 검사 표지로서 표적 유전자의 메틸화율을 검출하는 방법
WO2011092592A2 (en) 2010-01-26 2011-08-04 Nipd Genetics Ltd Methods and compositions for noninvasive prenatal diagnosis of fetal aneuploidies
US8278049B2 (en) 2010-04-26 2012-10-02 Ann & Robert H. Lurie Children's Hospital of Chicago Selective enrichment of CpG islands
US20120004132A1 (en) * 2010-07-02 2012-01-05 Affymetrix, Inc. Detection of Nucleic Acids and Proteins
JP5916058B2 (ja) * 2011-08-26 2016-05-11 国立大学法人東北大学 細胞ストレス状態のバイオマーカー
WO2013123481A1 (en) 2012-02-16 2013-08-22 Cornell University Methods and kit for characterizing the modified base status of a transcriptome
EP3037535A4 (en) * 2013-08-21 2017-04-05 Fujirebio Inc. Method for measuring modified nucleic-acid base using absorbent polynucleotide and kit therefor
EP3666902B1 (en) 2015-05-22 2024-07-03 Medicover Public Co Ltd Multiplexed parallel analysis of targeted genomic regions for non-invasive prenatal testing
KR101735415B1 (ko) * 2015-07-31 2017-05-16 한국과학기술연구원 헥산알 노출 특이적 메틸화 마커 유전자 및 이를 이용한 확인 방법
JP6900325B2 (ja) * 2016-01-27 2021-07-07 住友化学株式会社 センサーチップ及びセンシングシステム
SG11201807117WA (en) * 2016-02-23 2018-09-27 Dovetail Genomics Llc Generation of phased read-sets for genome assembly and haplotype phasing
CA3058807A1 (en) 2017-04-03 2018-10-11 Biontech Us Inc. Protein antigens and uses thereof
TW201930340A (zh) 2017-12-18 2019-08-01 美商尼恩醫療公司 新抗原及其用途
MX2020014243A (es) 2018-06-19 2021-05-12 Biontech Us Inc Neoantigenos y usos de los mismos.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654183A (en) * 1992-07-27 1997-08-05 California Institute Of Technology Genetically engineered mammalian neural crest stem cells
US5518901A (en) * 1993-04-19 1996-05-21 Murtagh; James J. Methods for adapting nucleic acid for detection, sequencing, and cloning using exonuclease
US5714325A (en) * 1993-09-24 1998-02-03 New England Medical Center Hospitals Prenatal diagnosis by isolation of fetal granulocytes from maternal blood
US5866323A (en) * 1995-04-07 1999-02-02 Case Western Reserve University Cancer diagnosis prognosis and therapy based on mutation of receptors for transforming growth factor β and homologous growth controlling factors
US6251594B1 (en) * 1997-06-09 2001-06-26 Usc/Norris Comprehensive Cancer Ctr. Cancer diagnostic method based upon DNA methylation differences
US6337392B1 (en) * 1998-05-07 2002-01-08 The Rockefeller University Lens transcriptional control elements and methods of use thereof
US6994971B1 (en) * 1999-10-08 2006-02-07 University Of Utah Research Foundation Particle analysis assay for biomolecular quantification
EP1231937A2 (en) * 1999-11-19 2002-08-21 Thomas V. Tittle Tr3-specific binding agents and methods for their use
EP1339868A2 (en) * 2000-06-23 2003-09-03 The University of Chicago Methods for isolating centromere dna
US20030157481A1 (en) * 2001-12-10 2003-08-21 Benjamin Thomas L. Diagnosing and treating cancer cells using T-HR mutants and their targets
US20020197639A1 (en) * 2001-06-08 2002-12-26 Shia Michael A. Methods and products for analyzing nucleic acids based on methylation status
AU2003206443A1 (en) * 2002-02-20 2003-09-09 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Hedgehog-related prophylaxis, therapy and diagnosis of gi tract carcinogenesis
DK1400589T3 (da) * 2002-09-18 2006-11-27 Sirs Lab Gmbh Fremgangsmåde til påvisning af prokaryotisk DNA
AU2003900368A0 (en) * 2003-01-24 2003-02-13 Human Genetic Signatures Pty Ltd Assay for nucleic acid molecules
JP3854943B2 (ja) * 2003-05-23 2006-12-06 独立行政法人科学技術振興機構 Dnaメチル化率の測定方法
EP1524523A1 (en) * 2003-10-17 2005-04-20 Deutsches Krebsforschungszentrum Stiftung Des Öffentlichen Rechts Use of ADAM 12 for diagnosis and therapy of preeclampsia
DE602005023710D1 (de) * 2004-02-20 2010-11-04 Japan Science & Tech Agency Dna-array zur analyse der dna-methylierung, konstruktionsverfahren dafür sowie verfahren zur analyse der dna-methylierung

Similar Documents

Publication Publication Date Title
JP2008502332A5 (https=)
Reeser et al. Validation of a targeted RNA sequencing assay for kinase fusion detection in solid tumors
CN116157533A (zh) 使用杂交方法捕获遗传靶标
Cresci et al. Heart failure in the era of precision medicine: a scientific statement from the American Heart Association
CN106029900B (zh) 尿生物标志物群、基因表达特征及其使用方法
US11345957B2 (en) Methods of treating glioblastoma in a subject informed by exosomal RNA signatures
CN110760936B (zh) 构建dna甲基化文库的方法及其应用
KR20170131516A (ko) 혈액 샘플 내의 순환 종양 세포의 디지털 분석
CN110257382A (zh) 识别肠癌血清标记物的核酸适配体及其筛选方法和用途
CA3224278A1 (en) Diagnosing inflammatory bowel diseases
CN108130368A (zh) lncRNA在制备诊断或预示青少年特发性脊柱侧凸产品中的应用
CN110806480B (zh) 肿瘤特异性细胞亚群和特征基因及其应用
Jain et al. Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system
TWI500770B (zh) Hoxa9基因作為檢測肝癌生物標記的用途
Kohwi et al. Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression
WO2012019786A1 (en) Method and kit for the diagnosis and/or prognosis of tolerance in liver transplantation
CN114752672B (zh) 基于循环游离DNA突变进行滤泡性淋巴瘤预后评估的检测panel、试剂盒及应用
CN106282361B (zh) 用于捕获血液病相关基因的基因捕获试剂盒
JP2024519082A (ja) 肝細胞がんのdnaメチル化バイオマーカー
CN104651522B (zh) I型胶原α1链的新应用
CN107881228A (zh) 一种与青少年特发性脊柱侧凸相关的分子标记物及其应用
CN104088019A (zh) 一种基于双分子荧光互补技术的肽适配子文库构建方法
WO2025096476A1 (en) Use of multi-nucleotide and structural variants for improved sensitivity and specificity of circulating tumor dna assays
CN108913772B (zh) 基于捕获测序的bMSI检测技术
WO2020163789A1 (en) Single cell/exosome/vesicle protein profiling