JP2008500275A - Ｎ末端の遊離チオールを有する新規な組み換えタンパク質 - Google Patents
Ｎ末端の遊離チオールを有する新規な組み換えタンパク質 Download PDFInfo
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- JP2008500275A JP2008500275A JP2006547297A JP2006547297A JP2008500275A JP 2008500275 A JP2008500275 A JP 2008500275A JP 2006547297 A JP2006547297 A JP 2006547297A JP 2006547297 A JP2006547297 A JP 2006547297A JP 2008500275 A JP2008500275 A JP 2008500275A
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- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
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- Health & Medical Sciences (AREA)
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- Molecular Biology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
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| US53361703P | 2003-12-31 | 2003-12-31 | |
| PCT/US2004/043081 WO2005065239A2 (en) | 2003-12-31 | 2004-12-23 | Novel recombinant proteins with n-terminal free thiol |
Publications (2)
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| JP2008500275A true JP2008500275A (ja) | 2008-01-10 |
| JP2008500275A5 JP2008500275A5 (https=) | 2008-02-21 |
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| EP (1) | EP1699920A4 (https=) |
| JP (1) | JP2008500275A (https=) |
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| AU (1) | AU2004311796A1 (https=) |
| CA (1) | CA2551131A1 (https=) |
| WO (1) | WO2005065239A2 (https=) |
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| JP2021517471A (ja) * | 2018-03-02 | 2021-07-26 | エリシオ セラピューティクス， インク．Ｅｌｉｃｉｏ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
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| TW201307390A (zh) | 2007-02-02 | 2013-02-16 | Amgen Inc | 海帕西啶（ｈｅｐｃｉｄｉｎ）、海帕西啶拮抗劑及使用方法 |
| EP2205280B1 (en) * | 2007-09-27 | 2019-09-04 | Amgen Inc. | Pharmaceutical formulations |
| EP2219602A1 (en) | 2007-11-15 | 2010-08-25 | Amgen, Inc | Aqueous formulation of erythropoiesis stimulating protein stablised by antioxidants for parenteral administration |
| ES2500066T3 (es) | 2008-01-25 | 2014-09-30 | Amgen, Inc | Anticuerpos frente a ferroportina y métodos de uso |
| CA2722600C (en) | 2008-05-01 | 2014-01-21 | Amgen Inc. | Anti-hepcidin antibodies and methods of use |
| JP6018753B2 (ja) | 2008-11-13 | 2016-11-02 | ザ・ジェネラル・ホスピタル・コーポレイションＴｈｅ Ｇｅｎｅｒａｌ Ｈｏｓｐｉｔａｌ Ｃｏｒｐｏｒａｔｉｏｎ | Ｂｍｐ−６の調節によって鉄の恒常性を制御するための方法および組成物 |
| MX344382B (es) | 2009-10-23 | 2016-12-14 | Amgen Inc * | Adaptador de vial y sistema. |
| WO2011156373A1 (en) | 2010-06-07 | 2011-12-15 | Amgen Inc. | Drug delivery device |
| CA2831100C (en) | 2011-03-31 | 2020-02-18 | Mark Dominis Holt | Vial adapter and system |
| EP2699293B8 (en) | 2011-04-20 | 2022-07-20 | Amgen Inc. | Autoinjector apparatus |
| EA018116B1 (ru) * | 2011-06-06 | 2013-05-30 | Общество С Ограниченной Ответственностью "Форт" (Ооо "Форт") | Способ получения ковалентного конъюгата полиэтиленгликоля с эритропоэтином |
| ES2675035T3 (es) | 2011-10-14 | 2018-07-05 | Amgen, Inc | Inyector y método de ensamblaje |
| EP3656426B1 (en) | 2012-11-21 | 2023-05-17 | Amgen Inc. | Drug delivery device |
| US9657098B2 (en) | 2013-03-15 | 2017-05-23 | Intrinsic Lifesciences, Llc | Anti-hepcidin antibodies and uses thereof |
| SG11201507417RA (en) | 2013-03-15 | 2015-10-29 | Amgen Inc | Body contour adaptable autoinjector device |
| EP2968760B1 (en) | 2013-03-15 | 2024-01-03 | Amgen Inc. | Drug cassette, autoinjector, and autoinjector system |
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Also Published As
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| US20090239790A1 (en) | 2009-09-24 |
| WO2005065239A2 (en) | 2005-07-21 |
| WO2005065239A3 (en) | 2005-11-24 |
| EP1699920A2 (en) | 2006-09-13 |
| US20050170457A1 (en) | 2005-08-04 |
| WO2005065239A8 (en) | 2006-08-17 |
| EP1699920A4 (en) | 2008-05-28 |
| CN1902311A (zh) | 2007-01-24 |
| CA2551131A1 (en) | 2005-07-21 |
| AU2004311796A1 (en) | 2005-07-21 |
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