JP2008297310A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008297310A5 JP2008297310A5 JP2008191184A JP2008191184A JP2008297310A5 JP 2008297310 A5 JP2008297310 A5 JP 2008297310A5 JP 2008191184 A JP2008191184 A JP 2008191184A JP 2008191184 A JP2008191184 A JP 2008191184A JP 2008297310 A5 JP2008297310 A5 JP 2008297310A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- vitamin
- composition according
- mpa
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 24
- -1 (3- (2-hydroxy-2-propyl) phenyl) methoxy Chemical group 0.000 claims 11
- 229930003316 Vitamin D Natural products 0.000 claims 6
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims 6
- 239000011710 vitamin D Substances 0.000 claims 6
- 235000019166 vitamin D Nutrition 0.000 claims 6
- 150000003710 vitamin D derivatives Chemical class 0.000 claims 6
- 229940046008 vitamin d Drugs 0.000 claims 6
- 239000003246 corticosteroid Substances 0.000 claims 4
- QWOJMRHUQHTCJG-UHFFFAOYSA-N CC([CH2-])=O Chemical class CC([CH2-])=O QWOJMRHUQHTCJG-UHFFFAOYSA-N 0.000 claims 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 3
- 201000004681 Psoriasis Diseases 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 3
- 229960002882 calcipotriol Drugs 0.000 claims 3
- LWQQLNNNIPYSNX-UROSTWAQSA-N calcipotriol Chemical compound C1([C@H](O)/C=C/[C@@H](C)[C@@H]2[C@]3(CCCC(/[C@@H]3CC2)=C\C=C\2C([C@@H](O)C[C@H](O)C/2)=C)C)CC1 LWQQLNNNIPYSNX-UROSTWAQSA-N 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- DTXXSJZBSTYZKE-ZDQKKZTESA-N Maxacalcitol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](OCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C DTXXSJZBSTYZKE-ZDQKKZTESA-N 0.000 claims 2
- 125000005907 alkyl ester group Chemical group 0.000 claims 2
- 229960005084 calcitriol Drugs 0.000 claims 2
- 239000011612 calcitriol Substances 0.000 claims 2
- 235000020964 calcitriol Nutrition 0.000 claims 2
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 239000003349 gelling agent Substances 0.000 claims 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229950006319 maxacalcitol Drugs 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 2
- 239000008252 pharmaceutical gel Substances 0.000 claims 2
- 210000004761 scalp Anatomy 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 229960004907 tacalcitol Drugs 0.000 claims 2
- BJYLYJCXYAMOFT-RSFVBTMBSA-N tacalcitol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CC[C@@H](O)C(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C BJYLYJCXYAMOFT-RSFVBTMBSA-N 0.000 claims 2
- 230000009974 thixotropic effect Effects 0.000 claims 2
- ODZFJAXAEXQSKL-WRJREGAQSA-N (1r,3s,5z)-5-[(2e)-2-[(1r,3as,7ar)-1-[(e,2r,5s)-5-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@@](C)(O)C(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C ODZFJAXAEXQSKL-WRJREGAQSA-N 0.000 claims 1
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 claims 1
- FFJCNSLCJOQHKM-CLFAGFIQSA-N (z)-1-[(z)-octadec-9-enoxy]octadec-9-ene Chemical compound CCCCCCCC\C=C/CCCCCCCCOCCCCCCCC\C=C/CCCCCCCC FFJCNSLCJOQHKM-CLFAGFIQSA-N 0.000 claims 1
- OCAPBUJLXMYKEJ-UHFFFAOYSA-N 1-[biphenyl-4-yl(phenyl)methyl]imidazole Chemical compound C1=NC=CN1C(C=1C=CC(=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 OCAPBUJLXMYKEJ-UHFFFAOYSA-N 0.000 claims 1
- FDCJDKXCCYFOCV-UHFFFAOYSA-N 1-hexadecoxyhexadecane Chemical compound CCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCC FDCJDKXCCYFOCV-UHFFFAOYSA-N 0.000 claims 1
- LEZWWPYKPKIXLL-UHFFFAOYSA-N 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole Chemical compound C1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 LEZWWPYKPKIXLL-UHFFFAOYSA-N 0.000 claims 1
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 1
- WJOHZNCJWYWUJD-IUGZLZTKSA-N Fluocinonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)COC(=O)C)[C@@]2(C)C[C@@H]1O WJOHZNCJWYWUJD-IUGZLZTKSA-N 0.000 claims 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 1
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims 1
- 150000005215 alkyl ethers Chemical class 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229940121375 antifungal agent Drugs 0.000 claims 1
- 239000003429 antifungal agent Substances 0.000 claims 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 claims 1
- 229960002537 betamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims 1
- 229960002206 bifonazole Drugs 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 235000019438 castor oil Nutrition 0.000 claims 1
- 229960003749 ciclopirox Drugs 0.000 claims 1
- SCKYRAXSEDYPSA-UHFFFAOYSA-N ciclopirox Chemical compound ON1C(=O)C=C(C)C=C1C1CCCCC1 SCKYRAXSEDYPSA-UHFFFAOYSA-N 0.000 claims 1
- 229960002842 clobetasol Drugs 0.000 claims 1
- CBGUOGMQLZIXBE-XGQKBEPLSA-N clobetasol propionate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]1(C)C[C@@H]2O CBGUOGMQLZIXBE-XGQKBEPLSA-N 0.000 claims 1
- 229960001146 clobetasone Drugs 0.000 claims 1
- XXIFVOHLGBURIG-OZCCCYNHSA-N clobetasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)CC2=O XXIFVOHLGBURIG-OZCCCYNHSA-N 0.000 claims 1
- 229960004022 clotrimazole Drugs 0.000 claims 1
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 claims 1
- 229960003913 econazole Drugs 0.000 claims 1
- XPYGGHVSFMUHLH-UUSULHAXSA-N falecalcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(O)(C(F)(F)F)C(F)(F)F)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C XPYGGHVSFMUHLH-UUSULHAXSA-N 0.000 claims 1
- 229950007545 falecalcitriol Drugs 0.000 claims 1
- 229960004884 fluconazole Drugs 0.000 claims 1
- RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 claims 1
- 229960003469 flumetasone Drugs 0.000 claims 1
- WXURHACBFYSXBI-GQKYHHCASA-N flumethasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]2(C)C[C@@H]1O WXURHACBFYSXBI-GQKYHHCASA-N 0.000 claims 1
- 229940043075 fluocinolone Drugs 0.000 claims 1
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 1
- 229960000785 fluocinonide Drugs 0.000 claims 1
- 229960003238 fluprednidene Drugs 0.000 claims 1
- YVHXHNGGPURVOS-SBTDHBFYSA-N fluprednidene Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@](C(=C)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 YVHXHNGGPURVOS-SBTDHBFYSA-N 0.000 claims 1
- 229960002714 fluticasone Drugs 0.000 claims 1
- MGNNYOODZCAHBA-GQKYHHCASA-N fluticasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(O)[C@@]2(C)C[C@@H]1O MGNNYOODZCAHBA-GQKYHHCASA-N 0.000 claims 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 1
- 229960000890 hydrocortisone Drugs 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 229960004125 ketoconazole Drugs 0.000 claims 1
- 229960002509 miconazole Drugs 0.000 claims 1
- 229960001664 mometasone Drugs 0.000 claims 1
- QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 claims 1
- 229960000988 nystatin Drugs 0.000 claims 1
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 claims 1
- 229960000987 paricalcitol Drugs 0.000 claims 1
- BPKAHTKRCLCHEA-UBFJEZKGSA-N paricalcitol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](\C=C\[C@H](C)C(C)(C)O)C)=C\C=C1C[C@@H](O)C[C@H](O)C1 BPKAHTKRCLCHEA-UBFJEZKGSA-N 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229920000259 polyoxyethylene lauryl ether Polymers 0.000 claims 1
- 229960002722 terbinafine Drugs 0.000 claims 1
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 claims 1
- 230000008719 thickening Effects 0.000 claims 1
- 229960005294 triamcinolone Drugs 0.000 claims 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 claims 1
- 229940070710 valerate Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24347100P | 2000-10-27 | 2000-10-27 | |
| US60/243,471 | 2000-10-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002537289A Division JP4451061B2 (ja) | 2000-10-27 | 2001-09-26 | 少なくとも１つのビタミンｄまたは１つのビタミンｄアナログおよび少なくとも１つのコルチコステロイドを含有する局所用組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013014295A Division JP5699169B2 (ja) | 2000-10-27 | 2013-01-29 | 少なくとも１つのビタミンｄまたは１つのビタミンｄアナログおよび少なくとも１つのコルチコステロイドを含有する局所用組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008297310A JP2008297310A (ja) | 2008-12-11 |
| JP2008297310A5 true JP2008297310A5 (enExample) | 2009-11-19 |
| JP5721927B2 JP5721927B2 (ja) | 2015-05-20 |
Family
ID=22918889
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002537289A Expired - Lifetime JP4451061B2 (ja) | 2000-10-27 | 2001-09-26 | 少なくとも１つのビタミンｄまたは１つのビタミンｄアナログおよび少なくとも１つのコルチコステロイドを含有する局所用組成物 |
| JP2008191184A Expired - Lifetime JP5721927B2 (ja) | 2000-10-27 | 2008-07-24 | 少なくとも１つのビタミンｄまたは１つのビタミンｄアナログおよび少なくとも１つのコルチコステロイドを含有する局所用組成物 |
| JP2013014295A Expired - Lifetime JP5699169B2 (ja) | 2000-10-27 | 2013-01-29 | 少なくとも１つのビタミンｄまたは１つのビタミンｄアナログおよび少なくとも１つのコルチコステロイドを含有する局所用組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002537289A Expired - Lifetime JP4451061B2 (ja) | 2000-10-27 | 2001-09-26 | 少なくとも１つのビタミンｄまたは１つのビタミンｄアナログおよび少なくとも１つのコルチコステロイドを含有する局所用組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013014295A Expired - Lifetime JP5699169B2 (ja) | 2000-10-27 | 2013-01-29 | 少なくとも１つのビタミンｄまたは１つのビタミンｄアナログおよび少なくとも１つのコルチコステロイドを含有する局所用組成物 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6787529B2 (enExample) |
| EP (1) | EP1331927B1 (enExample) |
| JP (3) | JP4451061B2 (enExample) |
| KR (1) | KR100844285B1 (enExample) |
| CN (1) | CN100382803C (enExample) |
| AT (1) | ATE380542T1 (enExample) |
| AU (2) | AU2001291637B2 (enExample) |
| BR (1) | BRPI0114927B8 (enExample) |
| CA (1) | CA2423930C (enExample) |
| CY (1) | CY1107294T1 (enExample) |
| CZ (1) | CZ305984B6 (enExample) |
| DE (1) | DE60131881T2 (enExample) |
| DK (1) | DK1331927T3 (enExample) |
| ES (1) | ES2298264T3 (enExample) |
| HU (1) | HU230005B1 (enExample) |
| IL (2) | IL154888A0 (enExample) |
| MX (1) | MXPA03003511A (enExample) |
| PL (1) | PL212660B1 (enExample) |
| PT (1) | PT1331927E (enExample) |
| RU (1) | RU2271810C2 (enExample) |
| WO (1) | WO2002034235A1 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8263580B2 (en) * | 1998-09-11 | 2012-09-11 | Stiefel Research Australia Pty Ltd | Vitamin formulation |
| US20090098065A1 (en) * | 2000-01-11 | 2009-04-16 | Avikam Harel | Composition and methods for the treatment of skin disorders |
| MXPA03003511A (es) * | 2000-10-27 | 2004-05-04 | Leo Pharma As | Composicion topica que contiene al menos una vitamina d o un analogo de vitamina de y al menos un corticosteroide. |
| US20090143328A1 (en) * | 2001-08-13 | 2009-06-04 | Mcdonald George | Method of Treating Cancer by Administration of Topical Active Corticosteroids |
| CA2505406A1 (en) * | 2002-12-17 | 2004-07-01 | Galderma Sa | Pharmaceutical compositions comprising a combination of calcitriol and a clobetasol propionate |
| FR2854802B1 (fr) * | 2003-05-12 | 2005-06-24 | Galderma Res & Dev | Procede de preparation d'une formulation contenant un principe actif microdose |
| US8404667B2 (en) * | 2006-12-29 | 2013-03-26 | Wisconsin Alumni Research Foundation | Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog |
| FR2871693B1 (fr) * | 2004-06-17 | 2006-08-25 | Galderma Sa | Utilisation d'une composition pharmaceutique comprenant du calcitriol et du propionate de clobetasol pour le traitement du psoriasis |
| FR2871698B1 (fr) * | 2004-06-17 | 2008-07-04 | Galderma Sa | Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse |
| FR2871700B1 (fr) * | 2004-06-17 | 2006-11-17 | Galderma Sa | Composition sous forme de spray comprenant une association d'actifs pharmaceutiques, une phase alcoolique, et une phase huileuse |
| FR2871696B1 (fr) * | 2004-06-17 | 2006-11-10 | Galderma Sa | Composition topique pour le traitement du psoriasis |
| FR2871694B1 (fr) * | 2004-06-17 | 2008-07-04 | Galderma Sa | Composition pharmaceutique comprenant un onguent oleagineux et deux principes actifs solubilises |
| FR2871697B1 (fr) * | 2004-06-17 | 2007-06-29 | Galderma Sa | Composition sous forme de spray comprenant une association d'actifs pharmaceutiques, une phase alcoolique, au moins un silicone volatile et une phase huileuse non volatile |
| CA2581693A1 (en) * | 2004-07-28 | 2006-02-02 | Lipopeptide Ab | New use |
| US7740875B2 (en) * | 2004-10-08 | 2010-06-22 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
| US20060078580A1 (en) | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
| AU2006245283B2 (en) | 2005-05-10 | 2012-11-01 | Dermipsor Ltd. | Compositions and methods for treating hyperproliferative epidermal diseases |
| EP1917072B1 (en) | 2005-06-01 | 2013-02-27 | Stiefel Research Australia Pty Ltd | Vitamin formulation |
| JP2008542423A (ja) * | 2005-06-10 | 2008-11-27 | ガルデルマ・ソシエテ・アノニム | 皮膚を通しての薬物の制御放出方法 |
| MXPA05009381A (es) * | 2005-09-02 | 2007-03-01 | Fernando Ahumada Ayala | Preparaciones para el cuidado de la piel que contienen mupirocina y dipropionato de betametasona. |
| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| US8679545B2 (en) | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
| US8324192B2 (en) | 2005-11-12 | 2012-12-04 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| ES2406735T3 (es) | 2006-03-17 | 2013-06-07 | Leo Pharma A/S | Isomerización de compuestos intermedios farmacéuticos |
| KR20110113664A (ko) * | 2006-08-29 | 2011-10-17 | 테바 파마슈티컬 인더스트리즈 리미티드 | 비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물 |
| FR2909284B1 (fr) * | 2006-11-30 | 2012-09-21 | Galderma Sa | Nouvelles compositions sous forme d'onguent sans vaseline comprenant un derive de vitamine d et eventuellement un anti-inflammatoire steroidien |
| ES2272198B1 (es) * | 2006-12-28 | 2008-06-01 | Laboratorios Viñas S.A. | Procedimiento para la obtencion de hidrato de calcipotriol. |
| US10265265B2 (en) | 2007-03-15 | 2019-04-23 | Drug Delivery Solutions Limited | Topical composition |
| EP1970049A1 (en) * | 2007-03-15 | 2008-09-17 | Drug Delivery Solutions Limited | Polyaphron topical composition with vitamin D and corticosteroid |
| EP1970048A1 (en) * | 2007-03-15 | 2008-09-17 | Drug Delivery Solutions Limited | Polyaphron topical composition with vitamin D |
| EP2008651A1 (en) | 2007-06-26 | 2008-12-31 | Drug Delivery Solutions Limited | A bioerodible patch |
| US20090123551A1 (en) * | 2007-11-13 | 2009-05-14 | Meritage Pharma, Inc. | Gastrointestinal delivery systems |
| HUE038452T2 (hu) | 2007-11-13 | 2018-10-29 | Meritage Pharma Inc | Gyomor és bélrendszeri gyulladások kezelésére szolgáló kompozíciók |
| US20100216754A1 (en) * | 2007-11-13 | 2010-08-26 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
| US9050368B2 (en) | 2007-11-13 | 2015-06-09 | Meritage Pharma, Inc. | Corticosteroid compositions |
| US20090264392A1 (en) * | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
| US9254296B2 (en) * | 2009-12-22 | 2016-02-09 | Leo Pharma A/S | Pharmaceutical composition comprising vitamin D analogue and cosolvent-surfactant mixture |
| BR112012015449B1 (pt) * | 2009-12-22 | 2021-09-28 | Leo Pharma A/S | Suspensão de monoidrato de calcipotriol, e, processo para preparar nanocristais de monoidrato de calcipotriol |
| US20120322776A1 (en) * | 2009-12-22 | 2012-12-20 | Leo Pharma A/S | Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants |
| KR101619077B1 (ko) | 2010-06-11 | 2016-05-10 | 레오 파마 에이/에스 | 비타민 ｄ 유사체 및 코르티코스테로이드를 포함하는 약제학적 분무 조성물 |
| RU2429818C1 (ru) * | 2010-06-28 | 2011-09-27 | Государственное учреждение здравоохранения "Кемеровская областная клиническая больница" | Лечебное средство |
| RU2442565C1 (ru) * | 2010-08-27 | 2012-02-20 | Государственное учреждение здравоохранения "Кемеровская областная клиническая больница" | Лечебная мазь |
| US8685381B2 (en) * | 2010-10-23 | 2014-04-01 | Joel Schlessinger | Topical base and active agent-containing compositions, and methods for improving and treating skin |
| US8968755B2 (en) | 2010-10-23 | 2015-03-03 | Joel Schlessinger | Topical base and active agent-containing compositions, and methods for improving and treating skin |
| BR112013023458B1 (pt) | 2011-03-14 | 2020-04-07 | Drug Delivery Solutions Ltd | composição oftálmica, e, método para fabricar a composição oftálmica |
| JP5897299B2 (ja) * | 2011-10-14 | 2016-03-30 | 岩城製薬株式会社 | ローション剤 |
| CN104138352B (zh) * | 2013-04-19 | 2018-02-27 | 江苏知原药业有限公司 | 卡泊三醇非水凝胶 |
| TW201636025A (zh) * | 2015-04-15 | 2016-10-16 | Maruho Kk | 皮膚用之醫藥組成物 |
| KR102643849B1 (ko) * | 2015-06-18 | 2024-03-07 | 밸리언트 파마슈티컬즈 노오쓰 아메리카 엘엘씨 | 건선을 치료하기 위한 코르티코스테로이드 및 레티노이드를 포함하는 국소 조성물 |
| EP3542788A1 (en) | 2018-03-19 | 2019-09-25 | MC2 Therapeutics Limited | Topical composition comprising calcipotriol and betamethasone dipropionate |
| KR102354028B1 (ko) | 2020-05-13 | 2022-01-24 | 동국대학교 경주캠퍼스 산학협력단 | 건선 예방, 개선 또는 치료용 피부 외용제 조성물 |
| CN114159567B (zh) * | 2020-09-10 | 2023-03-31 | 南京海融医药科技股份有限公司 | 一种治疗皮肤病的混悬凝胶剂 |
| CN115569199B (zh) * | 2022-02-14 | 2024-08-20 | 海勃(上海)医药科技有限公司 | 一种药物组合物及其制备方法和应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4569935A (en) * | 1983-03-17 | 1986-02-11 | University Of Tennessee Research Corp. | Topical treatment of psoriasis with imidazole antibiotics |
| US4610978A (en) * | 1983-03-22 | 1986-09-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same |
| SE457055B (sv) * | 1986-08-18 | 1988-11-28 | Ferring Ab | Topisk straalskyddsgel foer mukosa innehaallande kaerlsammandragande substanser |
| IL86170A (en) * | 1987-05-01 | 1992-12-01 | Elan Transdermal Ltd | Preparations and compositions comprising nicotine for percutaneous administration |
| US4847071A (en) | 1987-10-22 | 1989-07-11 | The Procter & Gamble Company | Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent |
| US5002938A (en) * | 1988-03-21 | 1991-03-26 | Bristol-Myers Squibb Company | Antifungal gel formulations |
| EP0437225B1 (de) * | 1990-01-10 | 1994-04-20 | F. Hoffmann-La Roche Ag | Topische Präparate |
| US5185150A (en) * | 1990-08-24 | 1993-02-09 | Wisconsin Alumni Research Fdn. | Cosmetic compositions containing 19-nor-vitamin D compounds |
| US5763428A (en) * | 1990-09-21 | 1998-06-09 | Bone Care International, Inc. | Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof |
| JP2571493B2 (ja) * | 1992-06-04 | 1997-01-16 | 株式会社資生堂 | 皮膚外用剤 |
| DE69325253T2 (de) * | 1992-08-28 | 1999-12-02 | Bone Care International Inc., Madison | 1alpha,24(s)-dihydroxy vitamin d2, seine synthese und verwendung |
| GB9226860D0 (en) * | 1992-12-23 | 1993-02-17 | Leo Pharm Prod Ltd | Novel treatment |
| DE4328217C2 (de) * | 1993-08-21 | 1996-01-11 | Lohmann Therapie Syst Lts | Therapeutisches System zur Behandlung der Psoriasis |
| US5708017A (en) * | 1995-04-04 | 1998-01-13 | Merck & Co., Inc. | Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors |
| FR2740042B1 (fr) * | 1995-10-23 | 1997-11-14 | Oreal | Support, et composition contenant ce support et un actif cosmetique ou dermatologique stabilise |
| JPH10158147A (ja) * | 1996-11-29 | 1998-06-16 | Kenji Nakamura | 皮膚保護用の被膜組成物とそれを用いた製品 |
| JP2001524087A (ja) * | 1997-04-18 | 2001-11-27 | クリンゲ ファーマ ジーエムビーエイチ | システイニル誘導体を含有する安定化された薬剤 |
| JPH11188054A (ja) * | 1997-12-25 | 1999-07-13 | Lion Corp | 皮膚外用部材 |
| US5990100A (en) | 1998-03-24 | 1999-11-23 | Panda Pharmaceuticals, L.L.C. | Composition and method for treatment of psoriasis |
| FR2785284B1 (fr) * | 1998-11-02 | 2000-12-01 | Galderma Res & Dev | Analogues de la vitamine d |
| ES2388425T5 (es) * | 1999-04-23 | 2020-02-12 | Leo Pharma As | Composición farmacéutica no acuosa para uso dérmico para tratar la psoriasis que comprende una vitamina D, un corticoesteroide y un componente disolvente |
| MXPA03003511A (es) * | 2000-10-27 | 2004-05-04 | Leo Pharma As | Composicion topica que contiene al menos una vitamina d o un analogo de vitamina de y al menos un corticosteroide. |
-
2001
- 2001-09-26 MX MXPA03003511A patent/MXPA03003511A/es active IP Right Grant
- 2001-09-26 HU HU0302881A patent/HU230005B1/hu unknown
- 2001-09-26 DK DK01971719T patent/DK1331927T3/da active
- 2001-09-26 CZ CZ2003-1162A patent/CZ305984B6/cs not_active IP Right Cessation
- 2001-09-26 IL IL15488801A patent/IL154888A0/xx unknown
- 2001-09-26 KR KR1020037005809A patent/KR100844285B1/ko not_active Expired - Lifetime
- 2001-09-26 BR BRPI0114927A patent/BRPI0114927B8/pt not_active IP Right Cessation
- 2001-09-26 DE DE60131881T patent/DE60131881T2/de not_active Expired - Lifetime
- 2001-09-26 RU RU2003115616/15A patent/RU2271810C2/ru active
- 2001-09-26 ES ES01971719T patent/ES2298264T3/es not_active Expired - Lifetime
- 2001-09-26 WO PCT/DK2001/000613 patent/WO2002034235A1/en not_active Ceased
- 2001-09-26 AU AU2001291637A patent/AU2001291637B2/en not_active Expired
- 2001-09-26 AU AU9163701A patent/AU9163701A/xx active Pending
- 2001-09-26 CN CNB018177964A patent/CN100382803C/zh not_active Expired - Lifetime
- 2001-09-26 JP JP2002537289A patent/JP4451061B2/ja not_active Expired - Lifetime
- 2001-09-26 PT PT01971719T patent/PT1331927E/pt unknown
- 2001-09-26 CA CA002423930A patent/CA2423930C/en not_active Expired - Lifetime
- 2001-09-26 AT AT01971719T patent/ATE380542T1/de active
- 2001-09-26 EP EP01971719A patent/EP1331927B1/en not_active Expired - Lifetime
- 2001-09-26 PL PL360941A patent/PL212660B1/pl unknown
- 2001-10-26 US US09/984,072 patent/US6787529B2/en not_active Expired - Lifetime
-
2003
- 2003-03-12 IL IL154888A patent/IL154888A/en not_active IP Right Cessation
-
2008
- 2008-03-03 CY CY20081100243T patent/CY1107294T1/el unknown
- 2008-07-24 JP JP2008191184A patent/JP5721927B2/ja not_active Expired - Lifetime
-
2013
- 2013-01-29 JP JP2013014295A patent/JP5699169B2/ja not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004512297A5 (enExample) | ||
| JP2008297309A5 (enExample) | ||
| RU2003115616A (ru) | Композиции местного применения, содержащие, по меньшей мере, один витамин d или один аналог витамина d и, по меньшей мере, один кортикостероид | |
| EP1331927B1 (en) | Topical composition containing at least one vitamin d or one vitamin d analogue and at least one corticosteroid | |
| EP2915534B1 (en) | Pharmaceutical composition for dermal use to treat psoriasis comprising a vitamin D and a corticosteroid | |
| AU2001291637A1 (en) | Topical composition containing at least one vitamin D or one vitamin D analogue and at least one corticosteroid | |
| MX2009002337A (es) | Composiciones farmacologicamente estables que incluyen compuestos que contienen vitamina d y corticosteroides con compatibilidad con bajo ph. | |
| HK1077208B (en) | Topical composition containing at least one vitmin d or one vitamin d analogue and at least one corticosteroid | |
| HK1236104A1 (en) | Ointments for the topical treatment of psoriasis | |
| HK1236104A (en) | Ointments for the topical treatment of psoriasis |