BRPI0114927B8 - composição de gel farmacêutica não aquosa para aplicação na pele, e, uso de uma composição - Google Patents
composição de gel farmacêutica não aquosa para aplicação na pele, e, uso de uma composiçãoInfo
- Publication number
- BRPI0114927B8 BRPI0114927B8 BRPI0114927A BR0114927A BRPI0114927B8 BR PI0114927 B8 BRPI0114927 B8 BR PI0114927B8 BR PI0114927 A BRPI0114927 A BR PI0114927A BR 0114927 A BR0114927 A BR 0114927A BR PI0114927 B8 BRPI0114927 B8 BR PI0114927B8
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- skin
- application
- pharmaceutical gel
- aqueous pharmaceutical
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 239000008252 pharmaceutical gel Substances 0.000 title abstract 3
- 229940046008 vitamin d Drugs 0.000 abstract 2
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Abstract
"composição de gel farmacêutica substancialmente não aquosa para aplicação na pele, e, uso da composição". a presente invenção diz respeito a uma composição farmacêutica em gel para aplicação na pele, a dita composição compreendendo pelo menos uma vitamina d ou análogo de vitamina d e pelo menos um corticosteróide bem como um excipiente que aumenta a viscosidade.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24347100P | 2000-10-27 | 2000-10-27 | |
PCT/DK2001/000613 WO2002034235A1 (en) | 2000-10-27 | 2001-09-26 | Topical composition containing at least one vitamin d or one vitamin d analogue and at least one corticosteroid |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0114927A BR0114927A (pt) | 2003-12-23 |
BR0114927B1 BR0114927B1 (pt) | 2017-12-05 |
BRPI0114927B8 true BRPI0114927B8 (pt) | 2021-05-25 |
Family
ID=22918889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0114927A BRPI0114927B8 (pt) | 2000-10-27 | 2001-09-26 | composição de gel farmacêutica não aquosa para aplicação na pele, e, uso de uma composição |
Country Status (22)
Country | Link |
---|---|
US (1) | US6787529B2 (pt) |
EP (1) | EP1331927B1 (pt) |
JP (3) | JP4451061B2 (pt) |
KR (1) | KR100844285B1 (pt) |
CN (1) | CN100382803C (pt) |
AT (1) | ATE380542T1 (pt) |
AU (2) | AU2001291637B2 (pt) |
BR (1) | BRPI0114927B8 (pt) |
CA (1) | CA2423930C (pt) |
CY (1) | CY1107294T1 (pt) |
CZ (1) | CZ305984B6 (pt) |
DE (1) | DE60131881T2 (pt) |
DK (1) | DK1331927T3 (pt) |
ES (1) | ES2298264T3 (pt) |
HK (1) | HK1077208A1 (pt) |
HU (1) | HU230005B1 (pt) |
IL (2) | IL154888A0 (pt) |
MX (1) | MXPA03003511A (pt) |
PL (1) | PL212660B1 (pt) |
PT (1) | PT1331927E (pt) |
RU (1) | RU2271810C2 (pt) |
WO (1) | WO2002034235A1 (pt) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8263580B2 (en) * | 1998-09-11 | 2012-09-11 | Stiefel Research Australia Pty Ltd | Vitamin formulation |
US20090098065A1 (en) * | 2000-01-11 | 2009-04-16 | Avikam Harel | Composition and methods for the treatment of skin disorders |
ES2298264T3 (es) * | 2000-10-27 | 2008-05-16 | Leo Pharma A/S | Composicion topica que contiene al menos una vitamina d o un analogo de vitamina d y al menos un corticoesteroide. |
US20090143328A1 (en) * | 2001-08-13 | 2009-06-04 | Mcdonald George | Method of Treating Cancer by Administration of Topical Active Corticosteroids |
MXPA05003805A (es) * | 2002-12-17 | 2005-06-08 | Galderma Sa | Composiciones farmaceuticas que comprenden una combinacion de calcitriol y propionato de clobetasol. |
US8404667B2 (en) * | 2006-12-29 | 2013-03-26 | Wisconsin Alumni Research Foundation | Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog |
FR2871696B1 (fr) * | 2004-06-17 | 2006-11-10 | Galderma Sa | Composition topique pour le traitement du psoriasis |
FR2871694B1 (fr) * | 2004-06-17 | 2008-07-04 | Galderma Sa | Composition pharmaceutique comprenant un onguent oleagineux et deux principes actifs solubilises |
FR2871698B1 (fr) * | 2004-06-17 | 2008-07-04 | Galderma Sa | Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse |
FR2871693B1 (fr) * | 2004-06-17 | 2006-08-25 | Galderma Sa | Utilisation d'une composition pharmaceutique comprenant du calcitriol et du propionate de clobetasol pour le traitement du psoriasis |
FR2871697B1 (fr) * | 2004-06-17 | 2007-06-29 | Galderma Sa | Composition sous forme de spray comprenant une association d'actifs pharmaceutiques, une phase alcoolique, au moins un silicone volatile et une phase huileuse non volatile |
FR2871700B1 (fr) * | 2004-06-17 | 2006-11-17 | Galderma Sa | Composition sous forme de spray comprenant une association d'actifs pharmaceutiques, une phase alcoolique, et une phase huileuse |
EP1781302A4 (en) * | 2004-07-28 | 2010-02-17 | Lipopeptide Ab | NEW USE |
US20060078580A1 (en) | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
DK1879595T3 (en) * | 2005-05-10 | 2015-01-05 | Dermipsor Ltd | Preparations and Methods for the Treatment of Hyperproliferative Epidermal Diseases |
NZ563560A (en) | 2005-06-01 | 2009-11-27 | Stiefel Res Australia Pty Ltd | Vitamin formulation for treating a dermatological skin disorder |
WO2006131401A2 (en) * | 2005-06-10 | 2006-12-14 | Galderma S.A. | Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent |
MXPA05009381A (es) * | 2005-09-02 | 2007-03-01 | Fernando Ahumada Ayala | Preparaciones para el cuidado de la piel que contienen mupirocina y dipropionato de betametasona. |
US8679545B2 (en) | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
US8324192B2 (en) | 2005-11-12 | 2012-12-04 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
EP1844010B1 (en) | 2006-03-17 | 2013-02-13 | Leo Pharma A/S | Isomerisation of pharmaceutical intermediates |
KR20090039833A (ko) * | 2006-08-29 | 2009-04-22 | 테바 파마슈티컬 인더스트리즈 리미티드 | 비타민 d 및 코르티코스테로이드를 포함하는 약학 조성물 |
FR2909284B1 (fr) * | 2006-11-30 | 2012-09-21 | Galderma Sa | Nouvelles compositions sous forme d'onguent sans vaseline comprenant un derive de vitamine d et eventuellement un anti-inflammatoire steroidien |
ES2272198B1 (es) * | 2006-12-28 | 2008-06-01 | Laboratorios Viñas S.A. | Procedimiento para la obtencion de hidrato de calcipotriol. |
EP1970048A1 (en) * | 2007-03-15 | 2008-09-17 | Drug Delivery Solutions Limited | Polyaphron topical composition with vitamin D |
EP1970049A1 (en) * | 2007-03-15 | 2008-09-17 | Drug Delivery Solutions Limited | Polyaphron topical composition with vitamin D and corticosteroid |
US10265265B2 (en) | 2007-03-15 | 2019-04-23 | Drug Delivery Solutions Limited | Topical composition |
EP2008651A1 (en) | 2007-06-26 | 2008-12-31 | Drug Delivery Solutions Limited | A bioerodible patch |
US20100216754A1 (en) * | 2007-11-13 | 2010-08-26 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
US20090123551A1 (en) * | 2007-11-13 | 2009-05-14 | Meritage Pharma, Inc. | Gastrointestinal delivery systems |
US8865692B2 (en) | 2007-11-13 | 2014-10-21 | Meritage Pharma, Inc | Compositions for the treatment of gastrointestinal inflammation |
CA2704957A1 (en) | 2007-11-13 | 2009-05-22 | Meritage Pharma, Inc. | Compositions for the treatment of gastrointestinal inflammation |
US20090264392A1 (en) * | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
US9254296B2 (en) * | 2009-12-22 | 2016-02-09 | Leo Pharma A/S | Pharmaceutical composition comprising vitamin D analogue and cosolvent-surfactant mixture |
US20130039952A1 (en) * | 2009-12-22 | 2013-02-14 | Leo Pharma A/S | Calcipotriol monohydrate nanocrystals |
AU2010335654B2 (en) * | 2009-12-22 | 2015-04-09 | Leo Pharma A/S | Cutaneous composition comprising vitamin D analogue and a mixture of solvent and surfactants |
PL2579852T3 (pl) | 2010-06-11 | 2015-04-30 | Leo Pharma As | Farmaceutyczna kompozycja sprayu zawierająca analog witaminy D i kortykosteroid |
US8968755B2 (en) | 2010-10-23 | 2015-03-03 | Joel Schlessinger | Topical base and active agent-containing compositions, and methods for improving and treating skin |
US8685381B2 (en) * | 2010-10-23 | 2014-04-01 | Joel Schlessinger | Topical base and active agent-containing compositions, and methods for improving and treating skin |
PT2686017T (pt) | 2011-03-14 | 2019-10-24 | Drug Delivery Solutions Ltd | Uma composição oftálmica. |
JP5897299B2 (ja) * | 2011-10-14 | 2016-03-30 | 岩城製薬株式会社 | ローション剤 |
CN104138352B (zh) * | 2013-04-19 | 2018-02-27 | 江苏知原药业有限公司 | 卡泊三醇非水凝胶 |
TW201636025A (zh) * | 2015-04-15 | 2016-10-16 | Maruho Kk | 皮膚用之醫藥組成物 |
JP6997624B2 (ja) * | 2015-06-18 | 2022-01-17 | ボシュ ヘルス ユーエス,エルエルシー. | 乾癬を治療するためのコルチコステロイドおよびレチノイドを含む局所用組成物 |
EP3542788A1 (en) | 2018-03-19 | 2019-09-25 | MC2 Therapeutics Limited | Topical composition comprising calcipotriol and betamethasone dipropionate |
KR102354028B1 (ko) | 2020-05-13 | 2022-01-24 | 동국대학교 경주캠퍼스 산학협력단 | 건선 예방, 개선 또는 치료용 피부 외용제 조성물 |
CN114159567B (zh) * | 2020-09-10 | 2023-03-31 | 南京海融医药科技股份有限公司 | 一种治疗皮肤病的混悬凝胶剂 |
CN115569199A (zh) * | 2022-02-14 | 2023-01-06 | 南京海融医药科技股份有限公司 | 一种药物组合物及其制备方法和应用 |
Family Cites Families (22)
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US4569935A (en) * | 1983-03-17 | 1986-02-11 | University Of Tennessee Research Corp. | Topical treatment of psoriasis with imidazole antibiotics |
US4610978A (en) * | 1983-03-22 | 1986-09-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same |
SE457055B (sv) * | 1986-08-18 | 1988-11-28 | Ferring Ab | Topisk straalskyddsgel foer mukosa innehaallande kaerlsammandragande substanser |
IL86170A (en) * | 1987-05-01 | 1992-12-01 | Elan Transdermal Ltd | Preparations and compositions comprising nicotine for percutaneous administration |
US4847071A (en) | 1987-10-22 | 1989-07-11 | The Procter & Gamble Company | Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent |
US5002938A (en) * | 1988-03-21 | 1991-03-26 | Bristol-Myers Squibb Company | Antifungal gel formulations |
DK0437225T3 (da) * | 1990-01-10 | 1994-06-27 | Hoffmann La Roche | Topiske præparater |
US5185150A (en) * | 1990-08-24 | 1993-02-09 | Wisconsin Alumni Research Fdn. | Cosmetic compositions containing 19-nor-vitamin D compounds |
US5763428A (en) * | 1990-09-21 | 1998-06-09 | Bone Care International, Inc. | Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof |
JP2571493B2 (ja) * | 1992-06-04 | 1997-01-16 | 株式会社資生堂 | 皮膚外用剤 |
DK0614456T3 (da) * | 1992-08-28 | 1999-12-06 | Bone Care Int Inc | 1alfa,24(S)-dihydroxy-vitamin D2, dets fremstilling og anvendelse |
GB9226860D0 (en) * | 1992-12-23 | 1993-02-17 | Leo Pharm Prod Ltd | Novel treatment |
DE4328217C2 (de) * | 1993-08-21 | 1996-01-11 | Lohmann Therapie Syst Lts | Therapeutisches System zur Behandlung der Psoriasis |
US5708017A (en) * | 1995-04-04 | 1998-01-13 | Merck & Co., Inc. | Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors |
FR2740042B1 (fr) * | 1995-10-23 | 1997-11-14 | Oreal | Support, et composition contenant ce support et un actif cosmetique ou dermatologique stabilise |
JPH10158147A (ja) * | 1996-11-29 | 1998-06-16 | Kenji Nakamura | 皮膚保護用の被膜組成物とそれを用いた製品 |
DE59712694D1 (de) * | 1997-04-18 | 2006-08-24 | Fritz Stanislaus | Stabilisiertes arzneimittel enthaltend cysteinylderivate |
JPH11188054A (ja) * | 1997-12-25 | 1999-07-13 | Lion Corp | 皮膚外用部材 |
US5990100A (en) | 1998-03-24 | 1999-11-23 | Panda Pharmaceuticals, L.L.C. | Composition and method for treatment of psoriasis |
FR2785284B1 (fr) * | 1998-11-02 | 2000-12-01 | Galderma Res & Dev | Analogues de la vitamine d |
NZ515142A (en) * | 1999-04-23 | 2004-01-30 | Leo Pharm Prod Ltd | Pharmaceutical composition |
ES2298264T3 (es) * | 2000-10-27 | 2008-05-16 | Leo Pharma A/S | Composicion topica que contiene al menos una vitamina d o un analogo de vitamina d y al menos un corticoesteroide. |
-
2001
- 2001-09-26 ES ES01971719T patent/ES2298264T3/es not_active Expired - Lifetime
- 2001-09-26 AU AU2001291637A patent/AU2001291637B2/en not_active Expired
- 2001-09-26 CA CA002423930A patent/CA2423930C/en not_active Expired - Lifetime
- 2001-09-26 JP JP2002537289A patent/JP4451061B2/ja not_active Expired - Lifetime
- 2001-09-26 PT PT01971719T patent/PT1331927E/pt unknown
- 2001-09-26 DE DE60131881T patent/DE60131881T2/de not_active Expired - Lifetime
- 2001-09-26 HU HU0302881A patent/HU230005B1/hu unknown
- 2001-09-26 AT AT01971719T patent/ATE380542T1/de active
- 2001-09-26 CN CNB018177964A patent/CN100382803C/zh not_active Expired - Lifetime
- 2001-09-26 PL PL360941A patent/PL212660B1/pl unknown
- 2001-09-26 IL IL15488801A patent/IL154888A0/xx unknown
- 2001-09-26 EP EP01971719A patent/EP1331927B1/en not_active Expired - Lifetime
- 2001-09-26 AU AU9163701A patent/AU9163701A/xx active Pending
- 2001-09-26 DK DK01971719T patent/DK1331927T3/da active
- 2001-09-26 WO PCT/DK2001/000613 patent/WO2002034235A1/en active IP Right Grant
- 2001-09-26 CZ CZ2003-1162A patent/CZ305984B6/cs not_active IP Right Cessation
- 2001-09-26 BR BRPI0114927A patent/BRPI0114927B8/pt not_active IP Right Cessation
- 2001-09-26 RU RU2003115616/15A patent/RU2271810C2/ru active
- 2001-09-26 KR KR1020037005809A patent/KR100844285B1/ko active IP Right Grant
- 2001-09-26 MX MXPA03003511A patent/MXPA03003511A/es active IP Right Grant
- 2001-10-26 US US09/984,072 patent/US6787529B2/en not_active Expired - Lifetime
-
2003
- 2003-03-12 IL IL154888A patent/IL154888A/en not_active IP Right Cessation
-
2005
- 2005-10-20 HK HK05109306A patent/HK1077208A1/xx not_active IP Right Cessation
-
2008
- 2008-03-03 CY CY20081100243T patent/CY1107294T1/el unknown
- 2008-07-24 JP JP2008191184A patent/JP5721927B2/ja not_active Expired - Lifetime
-
2013
- 2013-01-29 JP JP2013014295A patent/JP5699169B2/ja not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
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