JP2008289483A5 - - Google Patents
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- Publication number
- JP2008289483A5 JP2008289483A5 JP2008134696A JP2008134696A JP2008289483A5 JP 2008289483 A5 JP2008289483 A5 JP 2008289483A5 JP 2008134696 A JP2008134696 A JP 2008134696A JP 2008134696 A JP2008134696 A JP 2008134696A JP 2008289483 A5 JP2008289483 A5 JP 2008289483A5
- Authority
- JP
- Japan
- Prior art keywords
- eppf
- nucleic acid
- vector
- expression product
- mammalian cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 claims 35
- 108020004707 nucleic acids Proteins 0.000 claims 23
- 102000039446 nucleic acids Human genes 0.000 claims 23
- 150000007523 nucleic acids Chemical class 0.000 claims 23
- 239000000047 product Substances 0.000 claims 22
- 210000004962 mammalian cell Anatomy 0.000 claims 16
- 230000003321 amplification Effects 0.000 claims 15
- 238000003199 nucleic acid amplification method Methods 0.000 claims 15
- 230000000694 effects Effects 0.000 claims 7
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 5
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 5
- 241000894007 species Species 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 238000005096 rolling process Methods 0.000 claims 4
- 238000012360 testing method Methods 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 108091026890 Coding region Proteins 0.000 claims 2
- 108010017826 DNA Polymerase I Proteins 0.000 claims 2
- 102000004594 DNA Polymerase I Human genes 0.000 claims 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 108010058966 bacteriophage T7 induced DNA polymerase Proteins 0.000 claims 2
- 230000003197 catalytic effect Effects 0.000 claims 2
- 230000002068 genetic effect Effects 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 241000701844 Bacillus virus phi29 Species 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- FGUUSXIOTUKUDN-IBGZPJMESA-N C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 Chemical compound C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 FGUUSXIOTUKUDN-IBGZPJMESA-N 0.000 claims 1
- 108020004638 Circular DNA Proteins 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 108060002716 Exonuclease Proteins 0.000 claims 1
- 108010038807 Oligopeptides Proteins 0.000 claims 1
- 102000015636 Oligopeptides Human genes 0.000 claims 1
- 241001092905 Thermophis Species 0.000 claims 1
- 230000004075 alteration Effects 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 210000003578 bacterial chromosome Anatomy 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 239000012228 culture supernatant Substances 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 claims 1
- 102000013165 exonuclease Human genes 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 230000004060 metabolic process Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 230000000704 physical effect Effects 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- 108010068698 spleen exonuclease Proteins 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 230000005945 translocation Effects 0.000 claims 1
- 241001515965 unidentified phage Species 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200700765 | 2007-05-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008289483A JP2008289483A (ja) | 2008-12-04 |
| JP2008289483A5 true JP2008289483A5 (enExample) | 2011-07-07 |
Family
ID=38941851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008134696A Withdrawn JP2008289483A (ja) | 2007-05-25 | 2008-05-22 | 真核生物系において発現可能な形質転換体のスクリーニング |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20080299581A1 (enExample) |
| EP (1) | EP1997892A1 (enExample) |
| JP (1) | JP2008289483A (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI333977B (en) * | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| NZ597466A (en) * | 2007-03-01 | 2013-08-30 | Symphogen As | Recombinant anti-epidermal growth factor receptor antibody compositions |
| EP2331577B1 (en) * | 2008-08-29 | 2017-06-07 | Symphogen A/S | Recombinant anti-epidermal growth factor receptor antibody compositions |
| WO2010022738A1 (en) * | 2008-08-29 | 2010-03-04 | Symphogen A/S | Method for cloning avian-derived antibodies |
| EP3156504B1 (en) * | 2009-08-11 | 2018-10-31 | Sangamo Therapeutics, Inc. | Organisms homozygous for targeted modification |
| US9155802B2 (en) | 2010-11-01 | 2015-10-13 | Symphogen A/S | Pan-HER antibody composition |
| HK1202431A1 (en) | 2012-05-02 | 2015-10-02 | Symphogen A/S | Humanized pan-her antibody compositions |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1324227C (en) * | 1987-07-16 | 1993-11-09 | Masafumi Hongo | Impact resistant flame-retardant resin composition |
| US5198543A (en) | 1989-03-24 | 1993-03-30 | Consejo Superior Investigaciones Cientificas | PHI29 DNA polymerase |
| US5455166A (en) * | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| US6509189B1 (en) * | 1995-11-27 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding the cytoplasmic domain of human Ob receptor |
| GB0025144D0 (en) * | 2000-10-13 | 2000-11-29 | Medical Res Council | Concatenated nucleic acid sequences |
| US20060014149A1 (en) | 2002-08-01 | 2006-01-19 | Novozymes A/S | Methods for rolling circle amplification and signal trapping of libraries |
| GB0315160D0 (en) | 2003-06-28 | 2003-08-06 | Royal Holloway University Of L | In vitro amplification of DNA |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| MX2007000644A (es) * | 2004-07-20 | 2007-03-28 | Symphogen As | Anticuerpo policlonal recombinante anti-rhesus d y metodos de fabricacion. |
| PL1787126T3 (pl) * | 2004-07-20 | 2010-03-31 | Symphogen As | Sposób charakteryzowania poliklonalnej linii komórkowej |
| JP2009518320A (ja) * | 2005-12-05 | 2009-05-07 | シュムフォウエン アクティーゼルスカブ | 抗オルトポックスウイルス組換えポリクローナル抗体 |
| MX2008011280A (es) * | 2006-03-06 | 2008-09-12 | Symphogen As | Anticuerpor policlonal recombinante para el tratamiento de infecciones por el virus sincitial respiratorio. |
| JP5669397B2 (ja) * | 2007-03-01 | 2015-02-12 | シムフォゲン・アクティーゼルスカブＳｙｍｐｈｏｇｅｎ Ａ／Ｓ | 同族抗体をクローニングするための方法 |
| NZ597466A (en) * | 2007-03-01 | 2013-08-30 | Symphogen As | Recombinant anti-epidermal growth factor receptor antibody compositions |
| MX2009009226A (es) * | 2007-03-06 | 2009-10-28 | Symphogen As | Anticuerpos recombinantes para el tratamiento de infecciones con el virus respiratorio sincitial. |
| WO2010022738A1 (en) * | 2008-08-29 | 2010-03-04 | Symphogen A/S | Method for cloning avian-derived antibodies |
-
2008
- 2008-05-22 JP JP2008134696A patent/JP2008289483A/ja not_active Withdrawn
- 2008-05-23 US US12/153,804 patent/US20080299581A1/en not_active Abandoned
- 2008-05-23 EP EP08156793A patent/EP1997892A1/en not_active Withdrawn
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