JP2008133278A5 - - Google Patents
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- JP2008133278A5 JP2008133278A5 JP2007300664A JP2007300664A JP2008133278A5 JP 2008133278 A5 JP2008133278 A5 JP 2008133278A5 JP 2007300664 A JP2007300664 A JP 2007300664A JP 2007300664 A JP2007300664 A JP 2007300664A JP 2008133278 A5 JP2008133278 A5 JP 2008133278A5
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- JP
- Japan
- Prior art keywords
- group
- substituent
- atom
- salt
- general formula
- Prior art date
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007300664A JP4931775B2 (ja) | 2004-08-06 | 2007-11-20 | 芳香族化合物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004230092 | 2004-08-06 | ||
| JP2004230092 | 2004-08-06 | ||
| JP2005090149 | 2005-03-25 | ||
| JP2005090149 | 2005-03-25 | ||
| JP2007300664A JP4931775B2 (ja) | 2004-08-06 | 2007-11-20 | 芳香族化合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005229066A Division JP4154613B2 (ja) | 2004-08-06 | 2005-08-08 | 芳香族化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008133278A JP2008133278A (ja) | 2008-06-12 |
| JP2008133278A5 true JP2008133278A5 (enExample) | 2008-09-18 |
| JP4931775B2 JP4931775B2 (ja) | 2012-05-16 |
Family
ID=35508545
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005229066A Expired - Fee Related JP4154613B2 (ja) | 2004-08-06 | 2005-08-08 | 芳香族化合物 |
| JP2007300664A Expired - Fee Related JP4931775B2 (ja) | 2004-08-06 | 2007-11-20 | 芳香族化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005229066A Expired - Fee Related JP4154613B2 (ja) | 2004-08-06 | 2005-08-08 | 芳香族化合物 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8188277B2 (enExample) |
| EP (1) | EP1773797A2 (enExample) |
| JP (2) | JP4154613B2 (enExample) |
| KR (1) | KR100927563B1 (enExample) |
| CN (1) | CN1993339B (enExample) |
| AR (1) | AR050448A1 (enExample) |
| AU (1) | AU2005268030B2 (enExample) |
| BR (1) | BRPI0514150A (enExample) |
| CA (1) | CA2573223C (enExample) |
| IL (1) | IL180884A (enExample) |
| MX (1) | MX2007001215A (enExample) |
| MY (1) | MY148905A (enExample) |
| RU (1) | RU2416608C2 (enExample) |
| TW (1) | TWI353983B (enExample) |
| WO (1) | WO2006014012A2 (enExample) |
| ZA (1) | ZA200700811B (enExample) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2573223C (en) | 2004-08-06 | 2013-05-21 | Otsuka Pharmaceutical Co., Ltd. | Aromatic compound |
| WO2006076706A1 (en) | 2005-01-14 | 2006-07-20 | Millennium Pharmaceuticals, Inc. | Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity |
| EP1893609B1 (en) | 2005-06-16 | 2009-11-18 | Pfizer, Inc. | N-(pyridin-2-yl)-sulfonamide derivatives |
| WO2007031791A1 (en) | 2005-09-16 | 2007-03-22 | Arrow Therapeutics Limited | Biphenyl derivatives and their use in treating hepatitis c |
| ES2778846T3 (es) | 2005-11-08 | 2020-08-12 | Vertex Pharma | Moduladores heterocíclicos de transportadores de casete de unión a ATP |
| JP5142513B2 (ja) * | 2005-12-05 | 2013-02-13 | 大塚製薬株式会社 | 医薬 |
| CA2630468C (en) | 2005-12-05 | 2015-01-20 | Otsuka Pharmaceutical Co., Ltd. | Medicinal drug |
| ZA200804679B (en) | 2005-12-08 | 2010-02-24 | Millenium Pharmaceuticals Inc | Bicyclic compounds with kinase inhibitory activity |
| US7671221B2 (en) | 2005-12-28 | 2010-03-02 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| US7645789B2 (en) | 2006-04-07 | 2010-01-12 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
| USRE50453E1 (en) | 2006-04-07 | 2025-06-10 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
| NZ596889A (en) | 2006-04-07 | 2013-06-28 | Vertex Pharma | Use of amide indole derivatives as modulators of ATP-binding cassette transporters |
| US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| CA2659512C (en) * | 2006-06-06 | 2015-09-08 | Critical Therapeutics, Inc. | Novel piperazines, pharmaceutical compositions and methods of use thereof |
| US7943622B2 (en) | 2006-06-06 | 2011-05-17 | Cornerstone Therapeutics, Inc. | Piperazines, pharmaceutical compositions and methods of use thereof |
| PT2799427T (pt) | 2006-07-05 | 2018-10-16 | Fibrotech Therapeutics Pty Ltd | Compostos terapêuticos |
| AU2007286829B2 (en) * | 2006-08-21 | 2013-05-02 | Array Biopharma, Inc. | 4-substituted phenoxyphenylacetic acid derivatives |
| US8269010B2 (en) * | 2006-09-21 | 2012-09-18 | Piramal Healthcare Limited | 3-amino-pyridine derivatives for the treatment of metabolic disorders |
| AU2012202382B2 (en) * | 2006-10-02 | 2014-06-26 | Otsuka Pharmaceutical Co., Ltd. | STAT3/5 activation inhibitor |
| UA95978C2 (ru) * | 2006-10-02 | 2011-09-26 | Оцука Фармас'Ютікел Ко., Лтд. | Ингибитор активации stat3/5 |
| US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
| US7754739B2 (en) | 2007-05-09 | 2010-07-13 | Vertex Pharmaceuticals Incorporated | Modulators of CFTR |
| WO2008116145A2 (en) * | 2007-03-22 | 2008-09-25 | Arete Therapeutics, Inc. | Soluble epoxide hydrolase inhibitors |
| CN102863432B (zh) | 2007-05-09 | 2016-09-07 | 沃泰克斯药物股份有限公司 | Cftr调节剂 |
| JP2010536839A (ja) * | 2007-08-17 | 2010-12-02 | アストラゼネカ アクチボラグ | 化合物９７９ |
| WO2009076142A2 (en) | 2007-12-07 | 2009-06-18 | Vertex Pharmaceuticals Incorporated | Processes for producing cycloalkylcarboxiamido-pyridine benzoic acids |
| KR20150063170A (ko) | 2007-12-07 | 2015-06-08 | 버텍스 파마슈티칼스 인코포레이티드 | 3-(6-(1-(2,2-디플루오로벤조[ｄ][1,3]디옥솔-5-일)사이클로프로판카복스아미도)-3-메틸피리딘-2-일)벤조산의 고체 형태 |
| CN106432213A (zh) | 2008-02-28 | 2017-02-22 | 沃泰克斯药物股份有限公司 | 作为cftr调节剂的杂芳基衍生物 |
| FR2932483A1 (fr) * | 2008-06-13 | 2009-12-18 | Cytomics Systems | Composes utiles pour le traitement des cancers. |
| MX2011005037A (es) | 2008-11-21 | 2011-06-16 | High Point Pharmaceuticals Llc | Compuestos de adamantilo benzamida. |
| EA020460B1 (ru) | 2009-01-12 | 2014-11-28 | Пфайзер Лимитед | Производные сульфонамида |
| JP5688918B2 (ja) * | 2009-04-28 | 2015-03-25 | 大塚製薬株式会社 | 医薬組成物 |
| WO2011046954A1 (en) * | 2009-10-13 | 2011-04-21 | Ligand Pharmaceuticals Inc. | Hematopoietic growth factor mimetic small molecule compounds and their uses |
| IN2012DN03312A (enExample) | 2009-10-22 | 2015-10-23 | Fibrotech Therapeutics Pty Ltd | |
| AR080057A1 (es) * | 2010-01-29 | 2012-03-07 | Otsuka Pharma Co Ltd | Piridinas disustituidas como anticancerigenos |
| US8802868B2 (en) | 2010-03-25 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide |
| BR112012026255A2 (pt) | 2010-04-07 | 2017-03-14 | Vertex Pharma | composições farmacêuticas de ácido 3-(6-(1-(2-,2-difluorbenzo[d][1,3]dioxol-5-il)ciclopropanocarboxamido)-3-metilpiridin-2-il)benzóico e administração das mesmas |
| RU2745977C2 (ru) | 2010-04-22 | 2021-04-05 | Вертекс Фармасьютикалз Инкорпорейтед | Способ получения циклоалкилкарбоксамидо-индольных соединений |
| ES2532356T3 (es) | 2010-07-09 | 2015-03-26 | Pfizer Limited | N-sulfonilbenzamidas como inhibidores de los canales de sodio dependientes de voltaje |
| US8513430B2 (en) | 2010-07-27 | 2013-08-20 | High Point Pharmaceuticals, Llc | Substituted thiazol-2-ylamine derivatives, pharmaceutical compositions, and methods of use as 11-beta HSD1 modulators |
| EP2624833B1 (en) | 2010-10-04 | 2014-12-10 | Otsuka Pharmaceutical Co., Ltd. | 4-(methylaminophenoxy)pyrdin-3-yl-benzamide derivatives for treating cancer |
| DK2806859T3 (da) | 2012-01-25 | 2019-08-05 | Vertex Pharma | Formuleringer af 3-(6-(1-(2.2-difluorbenzo[d][1,3]dioxol-5-yl) cyclopropancarboxamido)-3-methylpyridin-2-yl)benzoesyre |
| AU2013290444B2 (en) | 2012-07-16 | 2018-04-26 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of (R)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide and administration thereof |
| JP5976224B2 (ja) * | 2012-08-31 | 2016-08-23 | ノバドラッグ， エルエルシー | ウイルス性疾患を処置するためのヘテロシクリルカルボキサミド |
| SG11201503959VA (en) * | 2012-11-20 | 2015-06-29 | Merial Inc | Anthelmintic compounds and compositions and method of using thereof |
| DK3068392T5 (da) | 2013-11-12 | 2021-09-20 | Vertex Pharma | Fremgangsmåde til fremstilling af farmaceutiske sammensætninger til behandlingen af cftr-medierede sygdomme |
| SG10201913575VA (en) | 2014-04-15 | 2020-02-27 | Vertex Pharma | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases |
| US10045979B2 (en) * | 2014-05-19 | 2018-08-14 | Merial Inc. | Anthelmintic compounds |
| WO2016081556A1 (en) | 2014-11-18 | 2016-05-26 | Vertex Pharmaceuticals Incorporated | Process of conducting high throughput testing high performance liquid chromatography |
| US10316021B2 (en) | 2016-11-28 | 2019-06-11 | Pfizer Inc. | Heteroarylphenoxy benzamide kappa opioid ligands |
| EP3577103A1 (en) | 2017-02-03 | 2019-12-11 | Certa Therapeutics Pty Ltd. | Anti-fibrotic compounds |
| WO2020059841A1 (ja) * | 2018-09-21 | 2020-03-26 | 国立大学法人 長崎大学 | プリオン病治療薬 |
| CN111847474B (zh) * | 2020-07-17 | 2021-09-28 | 浙江恒澜科技有限公司 | 一种Ti-ITQ-24沸石分子筛及其原位合成方法和应用 |
| AU2023224057A1 (en) * | 2022-02-28 | 2024-08-15 | Sironax Ltd. | Rip1 modulators, preparations, and uses thereof |
| CN116217511B (zh) * | 2023-03-22 | 2024-04-19 | 沈阳药科大学 | 一种双靶点化合物及其制备方法和在制备sEH抑制剂与PPARs激动剂中的应用 |
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| NL7111711A (enExample) | 1970-09-17 | 1972-03-21 | ||
| GB1494117A (en) | 1974-11-02 | 1977-12-07 | Bayer Ag | Process for the preparation of acid amides |
| DE2707659A1 (de) | 1977-02-23 | 1978-08-24 | Bayer Ag | Selbstvernetzbare polyurethane |
| DE2707660C2 (de) | 1977-02-23 | 1985-12-19 | Bayer Ag, 5090 Leverkusen | Abspalter- und Diolrest enthaltende Diisocyanat-Addukte, ihre Herstellung und Verwendung |
| DE2812252A1 (de) | 1978-03-21 | 1979-10-04 | Bayer Ag | 1,2,4-triazol-blockierte polyisocyanate als vernetzer fuer lackbindemittel |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
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| CA2630468C (en) | 2005-12-05 | 2015-01-20 | Otsuka Pharmaceutical Co., Ltd. | Medicinal drug |
| UA95978C2 (ru) | 2006-10-02 | 2011-09-26 | Оцука Фармас'Ютікел Ко., Лтд. | Ингибитор активации stat3/5 |
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-
2005
- 2005-08-03 CA CA2573223A patent/CA2573223C/en not_active Expired - Fee Related
- 2005-08-03 RU RU2007108298/04A patent/RU2416608C2/ru not_active IP Right Cessation
- 2005-08-03 CN CN2005800266964A patent/CN1993339B/zh not_active Expired - Fee Related
- 2005-08-03 WO PCT/JP2005/014611 patent/WO2006014012A2/en not_active Ceased
- 2005-08-03 ZA ZA200700811A patent/ZA200700811B/xx unknown
- 2005-08-03 US US11/659,689 patent/US8188277B2/en not_active Expired - Fee Related
- 2005-08-03 AU AU2005268030A patent/AU2005268030B2/en not_active Ceased
- 2005-08-03 KR KR1020077002786A patent/KR100927563B1/ko not_active Expired - Fee Related
- 2005-08-03 MX MX2007001215A patent/MX2007001215A/es active IP Right Grant
- 2005-08-03 EP EP05780290A patent/EP1773797A2/en not_active Withdrawn
- 2005-08-03 BR BRPI0514150-8A patent/BRPI0514150A/pt not_active IP Right Cessation
- 2005-08-05 MY MYPI20053673A patent/MY148905A/en unknown
- 2005-08-05 AR ARP050103285A patent/AR050448A1/es unknown
- 2005-08-08 TW TW094126788A patent/TWI353983B/zh not_active IP Right Cessation
- 2005-08-08 JP JP2005229066A patent/JP4154613B2/ja not_active Expired - Fee Related
-
2007
- 2007-01-22 IL IL180884A patent/IL180884A/en not_active IP Right Cessation
- 2007-11-20 JP JP2007300664A patent/JP4931775B2/ja not_active Expired - Fee Related
-
2012
- 2012-02-29 US US13/409,090 patent/US20120238750A1/en not_active Abandoned