JP2007537301A5 - - Google Patents

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Publication number
JP2007537301A5
JP2007537301A5 JP2007513481A JP2007513481A JP2007537301A5 JP 2007537301 A5 JP2007537301 A5 JP 2007537301A5 JP 2007513481 A JP2007513481 A JP 2007513481A JP 2007513481 A JP2007513481 A JP 2007513481A JP 2007537301 A5 JP2007537301 A5 JP 2007537301A5
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JP
Japan
Prior art keywords
composition
active agent
following
salts
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007513481A
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English (en)
Japanese (ja)
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JP2007537301A (ja
JP5254610B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/017309 external-priority patent/WO2005112633A2/en
Publication of JP2007537301A publication Critical patent/JP2007537301A/ja
Publication of JP2007537301A5 publication Critical patent/JP2007537301A5/ja
Application granted granted Critical
Publication of JP5254610B2 publication Critical patent/JP5254610B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007513481A 2004-05-14 2005-05-16 活性薬剤を送達するための化合物および組成物 Expired - Fee Related JP5254610B2 (ja)

Applications Claiming Priority (27)

Application Number Priority Date Filing Date Title
US57109304P 2004-05-14 2004-05-14
US57115104P 2004-05-14 2004-05-14
US57109004P 2004-05-14 2004-05-14
US57131504P 2004-05-14 2004-05-14
US57119504P 2004-05-14 2004-05-14
US57119404P 2004-05-14 2004-05-14
US57105504P 2004-05-14 2004-05-14
US57109204P 2004-05-14 2004-05-14
US57108904P 2004-05-14 2004-05-14
US57114404P 2004-05-14 2004-05-14
US60/571,151 2004-05-14
US60/571,092 2004-05-14
US60/571,195 2004-05-14
US60/571,089 2004-05-14
US60/571,194 2004-05-14
US60/571,144 2004-05-14
US60/571,090 2004-05-14
US60/571,315 2004-05-14
US60/571,093 2004-05-14
US60/571,055 2004-05-14
US57610504P 2004-06-01 2004-06-01
US57608804P 2004-06-01 2004-06-01
US57639704P 2004-06-01 2004-06-01
US60/576,397 2004-06-01
US60/576,088 2004-06-01
US60/576,105 2004-06-01
PCT/US2005/017309 WO2005112633A2 (en) 2004-05-14 2005-05-16 Compounds and compositions for delivering active agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011148239A Division JP5634342B2 (ja) 2004-05-14 2011-07-04 活性薬剤を送達するための化合物および組成物

Publications (3)

Publication Number Publication Date
JP2007537301A JP2007537301A (ja) 2007-12-20
JP2007537301A5 true JP2007537301A5 (https=) 2008-02-07
JP5254610B2 JP5254610B2 (ja) 2013-08-07

Family

ID=35428769

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007513481A Expired - Fee Related JP5254610B2 (ja) 2004-05-14 2005-05-16 活性薬剤を送達するための化合物および組成物
JP2011148239A Expired - Fee Related JP5634342B2 (ja) 2004-05-14 2011-07-04 活性薬剤を送達するための化合物および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011148239A Expired - Fee Related JP5634342B2 (ja) 2004-05-14 2011-07-04 活性薬剤を送達するための化合物および組成物

Country Status (12)

Country Link
US (1) US8273794B2 (https=)
EP (2) EP1756039B1 (https=)
JP (2) JP5254610B2 (https=)
KR (1) KR101299707B1 (https=)
AU (1) AU2005244904B2 (https=)
CA (1) CA2565188C (https=)
ES (1) ES2393324T3 (https=)
IL (2) IL179106A (https=)
MX (1) MXPA06013252A (https=)
NO (1) NO20065726L (https=)
NZ (2) NZ551196A (https=)
WO (1) WO2005112633A2 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2511530C (en) 2003-01-06 2013-07-09 Emisphere Technologies, Inc. Night-time oral insulin therapy
US20050203001A1 (en) 2004-03-05 2005-09-15 Emisphere Technologies, Inc. Oral insulin therapies and protocol
FR2880887B1 (fr) * 2005-01-14 2009-01-30 Merck Sante Soc Par Actions Si Derives d'hydroxyphenols, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
WO2007005995A2 (en) 2005-07-05 2007-01-11 Emisphere Technologies, Inc. Compositions for buccal delivery of human growth hormone
PL1971362T3 (pl) 2005-08-19 2015-05-29 Amylin Pharmaceuticals Llc Eksendyna do leczenia cukrzycy i zmniejszania masy ciała
WO2007121318A2 (en) 2006-04-12 2007-10-25 Emisphere Technologies, Inc. Formulations for delivering insulin
EP2016178B1 (en) 2006-05-02 2017-07-12 Intrexon Actobiotics NV Microbial intestinal delivery of obesity related peptides
US8771712B2 (en) 2006-05-09 2014-07-08 Emisphere Technologies, Inc. Topical administration of acyclovir
WO2008022267A2 (en) * 2006-08-17 2008-02-21 Wellstat Therapeutics Corporation Combination treatment for metabolic disorders
JP5544169B2 (ja) 2007-02-08 2014-07-09 エミスフェアー・テクノロジーズ・インク フェニルアルキルカルボン酸誘導体送達剤
WO2009143285A2 (en) 2008-05-21 2009-11-26 Amylin Pharmaceuticals, Inc. Exendins to lower cholestrol and triglycerides
US20110039930A1 (en) * 2009-08-03 2011-02-17 Emisphere Technologies, Inc. Fast-acting naproxen composition with reduced gastrointestinal effects
SI2651398T1 (en) 2010-12-16 2018-04-30 Novo Nordisk A/S SOLID COMPOSITIONS CONTAINING GLP-1 AGONIST AND SOL N- (8- (2-HYDROXYBENZOIL) AMINO) CAPRICULATE ACIDS
PL2696687T3 (pl) 2011-04-12 2017-06-30 Novo Nordisk A/S Pochodne podwójnie acylowanej GLP-1
US9422224B2 (en) * 2011-06-13 2016-08-23 Ergon Pharmaceuticals Llc Methods of treatment using a BCAT1 inhibitor
US10941109B2 (en) 2011-06-13 2021-03-09 Ergon Pharmaceuticals Llc Compositions and methods of treatment using a BCAT1 inhibitor
ES2965469T3 (es) 2012-03-22 2024-04-15 Novo Nordisk As Composiciones que comprenden un agente de suministro y preparación de estas
PT2827845T (pt) 2012-03-22 2019-03-29 Novo Nordisk As Composições compreendendo um agente de entrega e sua preparação
HRP20181447T1 (hr) 2012-03-22 2018-11-02 Novo Nordisk A/S Pripravci glp-1 peptida i njihova priprava
JP6517690B2 (ja) 2012-06-20 2019-05-22 ノヴォ ノルディスク アー／エス ペプチド及び送達剤を含む錠剤製剤
KR102272671B1 (ko) 2013-05-02 2021-07-06 노보 노르디스크 에이/에스 Glp-1 화합물의 경구 투여
WO2017160709A1 (en) * 2016-03-14 2017-09-21 West Virginia University Water soluble haloanilide calcium-release calcium channel inhibitory compounds and methods to control bone erosion and inflammation associated with arthritides
WO2019147650A1 (en) * 2018-01-23 2019-08-01 Gila Therapeutics, Inc. Peptide yy pharmaceutical formulations, compositions, and methods
JP6898518B2 (ja) 2018-02-02 2021-07-07 ノヴォ ノルディスク アー／エス Ｇｌｐ−１アゴニスト、ｎ−（８−（２−ヒドロキシベンゾイル）アミノ）カプリル酸の塩及び滑沢剤を含む固形組成物

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US35862A (en) 1862-07-08 Improved portable evaporator for saccharine jutces
GB842998A (en) * 1956-11-16 1960-08-04 Ici Ltd Process for the production of carboxylic acids by the oxidation of organic compounds
US3072473A (en) * 1959-10-07 1963-01-08 Us Rubber Co Plant growth regulants
US3046301A (en) 1959-10-29 1962-07-24 Burroughs Wellcome Co Method of making chlorambucil
US3510561A (en) 1965-05-20 1970-05-05 Canada Packers Ltd Sulfone-enhanced heparin absorption through mucous membranes
FR2420522A1 (fr) * 1978-03-20 1979-10-19 Unicler Derives de l'acide (m-benzoyl-phenoxy)-2 propionique et leurs applications comme medicaments
US4666902A (en) * 1983-06-20 1987-05-19 Cassella Aktiengesellschaft Tetrahydropyridazinone derivatives, processes for their preparation and their use
USRE35862E (en) 1986-08-18 1998-07-28 Emisphere Technologies, Inc. Delivery systems for pharmacological agents encapsulated with proteinoids
FI875101L (fi) 1986-12-03 1988-06-04 Tanabe Seiyaku Co Laktamderivat och preparat innehaollande dessa.
FR2616661B1 (fr) 1987-06-19 1991-06-07 Doutremepuich Christian Composition a base de mucopolysaccharides hepariniques, active par voie orale
US5541155A (en) 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5693338A (en) 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5443841A (en) 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US6916489B2 (en) 1992-06-15 2005-07-12 Emisphere Technologies, Inc. Active agent transport systems
US5366519A (en) 1992-12-18 1994-11-22 Chevron Research And Technology Company Fuel additive compositions containing poly(oxyalkylene) hydroxyaromatic esters and poly(oxyalkylene) amines
US5401516A (en) 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US5643957A (en) 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US20010003001A1 (en) 1993-04-22 2001-06-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US20040062773A1 (en) 1993-04-22 2004-04-01 Emisphere Technologies Inc. Compositions for the delivery of antigens
AU6819294A (en) * 1993-04-22 1994-11-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US6461643B2 (en) 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
SE9302135D0 (sv) 1993-06-18 1993-06-18 Kabi Pharmacia Ab New pharmaceutical composition
US5650386A (en) * 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5965121A (en) 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CN1151836C (zh) 1995-03-31 2004-06-02 艾米斯菲尔技术有限公司 用作传送活性剂的化合物和组合物
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5989539A (en) 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5820881A (en) 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
IL126318A (en) 1996-03-29 2004-09-27 Emisphere Tech Inc Compounds and compositions for delivering active agents and some novel carrier compounds
CA2258264A1 (en) 1996-06-14 1997-12-18 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
CA2271788A1 (en) 1996-11-13 1998-05-22 University Of Cincinnati Analogs of peptide yy and uses thereof
WO1998021951A1 (en) 1996-11-18 1998-05-28 Emisphere Technologies, Inc. Methods and compositions for inducing oral tolerance in mammals
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US5776888A (en) 1997-02-07 1998-07-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
ATE383169T1 (de) * 1997-02-07 2008-01-15 Emisphere Tech Inc Komponente und zusammensetzungen zur verabreichung von wirkstoffen
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) * 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
AU745081B2 (en) * 1997-06-27 2002-03-14 Fujisawa Pharmaceutical Co., Ltd. Sulfonamide compounds and medicinal use thereof
IN186245B (https=) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
WO1999044642A1 (en) 1998-03-05 1999-09-10 Phares Pharmaceutical Research Nv Pharmaceutical compositions and their use
TWI243828B (en) * 1998-03-19 2005-11-21 Vertex Pharma Inhibitors of caspases
JP5144861B2 (ja) 1998-07-27 2013-02-13 エミスフェアー・テクノロジーズ・インク 活性剤のデリバリーのための化合物及び組成物
US6440929B1 (en) 1998-07-27 2002-08-27 Emisphere Technologies, Inc. Pulmonary delivery of active agents
IL140930A0 (en) * 1998-08-07 2002-02-10 Emisphere Tech Inc Compounds and compositions for delivering active agents
WO2000022909A2 (en) 1998-10-19 2000-04-27 Biotech Australia Pty. Limited Systems for oral delivery
IL143226A0 (en) 1998-11-20 2002-04-21 Hoffmann La Roche Pyrrolidine derivatives-ccr-3 receptor antagonists
JP2002534363A (ja) 1999-01-08 2002-10-15 エミスフェアー・テクノロジーズ・インク ポリマー性デリバリー剤及びデリバリー剤化合物
AU3357800A (en) 1999-02-05 2000-08-25 Emisphere Technologies, Inc. Method of preparing alkylated salicylamides
ES2251976T3 (es) 1999-02-11 2006-05-16 Emisphere Technologies, Inc. Compuestos y composiciones de oxadiazol para aportar agentes activos.
MXPA01008611A (es) 1999-02-26 2003-06-24 Emisphere Tech Inc Compuestos y composiciones para suministrar agentes activos.
ES2235854T3 (es) 1999-04-05 2005-07-16 Emisphere Technologies, Inc. Sales disodicas, monohidratos y solvatos etanolicos para aportar agentes activos.
EP1183017A1 (en) * 1999-05-28 2002-03-06 Abbott Laboratories Novel formulations comprising lipid-regulating agents
US6458383B2 (en) 1999-08-17 2002-10-01 Lipocine, Inc. Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin
MXPA02004092A (es) 1999-11-05 2003-02-12 Emisphere Tech Inc Compuestos y composiciones de acido fenilaminocarboxilico para administrar agentes activos.
DE20022960U1 (de) 1999-11-12 2002-07-25 Emisphere Technologies, Inc., Tarrytown, N.Y. Flüssige Heparinformulierung
ES2298168T3 (es) 1999-12-16 2008-05-16 Emisphere Technologies, Inc. Compuestos y composiciones para suministrar agentes activos.
US7151191B2 (en) 2000-01-13 2006-12-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6384278B1 (en) 2000-02-04 2002-05-07 Emisphere Technologies, Inc. Boron-mediated amidation of carboxylic acids
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
US6900344B2 (en) 2000-03-21 2005-05-31 Emisphere Technologies, Inc. Method of preparing alkylated salicylamides via a dicarboxylate intermediate
WO2001092206A1 (en) 2000-06-02 2001-12-06 Emisphere Technologies, Inc. Method of preparing salicylamides
ES2306719T3 (es) * 2000-06-29 2008-11-16 Emisphere Technologies, Inc. Compuestos y composiciones para la administracion de principios activos.
US6451814B1 (en) * 2000-07-17 2002-09-17 Wyeth Heterocyclic β-3 adrenergic receptor agonists
US6446795B1 (en) 2000-07-31 2002-09-10 The Gillette Company Towelette packaging
US7138546B2 (en) 2000-08-18 2006-11-21 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
WO2002015959A2 (en) 2000-08-18 2002-02-28 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
AU2002211805A1 (en) 2000-09-06 2002-03-22 Emisphere Technologies, Inc. Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents
AU2001296865A1 (en) 2000-09-06 2002-03-22 Emisphere Technologies, Inc. (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
EP2123293A3 (en) 2000-12-14 2010-09-08 Amylin Pharmaceuticals, Inc. Peptide YY and petide YY agonists for treatment of metabolic disorders
JP2004530658A (ja) 2001-03-01 2004-10-07 エミスフェアー・テクノロジーズ・インク 活性剤を送達するための化合物および組成物
NZ527157A (en) 2001-03-01 2005-04-29 Emisphere Tech Inc Compositions for delivering bisphosphonates
US20030225300A1 (en) 2001-04-19 2003-12-04 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US7034059B2 (en) 2001-07-02 2006-04-25 Sepracor Inc. Methods of using norfluoxetine
ES2400683T3 (es) 2001-09-26 2013-04-11 Emisphere Technologies, Inc. Método de preparación de ácidos fenoi-alcanoicos y sales de los mismos mediante un producto intermedio de dicarboxilato
AU2002360387B2 (en) 2001-11-13 2008-08-07 Emisphere Technologies, Inc. Phenoxy amine compounds and compositions for delivering active agents
CA2466863A1 (en) * 2001-11-29 2003-06-05 Emisphere Technologies, Inc. Oral pharmaceutical compositions comprising cromolyn sodium and an acylated amino acid
US20030198666A1 (en) * 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
EP1469827B1 (en) 2002-01-09 2017-12-27 Emisphere Technologies, Inc. Polymorphs of sodium 4- (4-chloro-2-hydroxybenzoyl)amino butanoate
US7153983B2 (en) 2002-03-25 2006-12-26 Council Of Scientific And Industrial Research Chemo-enzymatic process for the preparation of opticaly enriched β-benzyl-γ-butyrolactones
US20050054557A1 (en) * 2002-05-09 2005-03-10 Goldberg Michael M. Compositions for delivering parathyroid hormone and calcitonin
EP1664327B1 (en) * 2002-08-29 2011-10-05 American Diagnostica, Inc. METHODS OF SCREENING FOR COMPOUNDS THAT MODULATE TAFIa ACTIVITY, COMPOUNDS, AND METHODS OF USING THE COMPOUNDS
CA2511530C (en) 2003-01-06 2013-07-09 Emisphere Technologies, Inc. Night-time oral insulin therapy
EP1605895A4 (en) 2003-03-06 2011-08-24 Emisphere Tech Inc ORAL INSULIN THERAPIES AND PROTOCOL
JP2006519881A (ja) * 2003-03-06 2006-08-31 エミスフィアー テクノロジーズ インコーポレイテッド 経口インスリン治療及びプロトコール
BRPI0411165A (pt) 2003-05-14 2006-07-11 Emisphere Tech Inc composição farmacêutica, forma de unidade de dosagem e métodos para preparar seu uso
US20070005005A1 (en) 2003-08-29 2007-01-04 Wang Fang N Method and apparatus for dosing solids
JP2007536268A (ja) * 2004-05-06 2007-12-13 エミスフェアー・テクノロジーズ・インク 固体剤形の湿性ヘパリン
EP1773376A4 (en) * 2004-08-03 2009-07-01 Emisphere Tech Inc ANTIDIBLE ORAL INSULIN BIGUANIDE COMBINATION
US8110547B2 (en) * 2005-01-12 2012-02-07 Emisphere Technologies, Inc. Compositions for buccal delivery of parathyroid hormone

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