JP2007534308A5 - - Google Patents
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- Publication number
- JP2007534308A5 JP2007534308A5 JP2006541541A JP2006541541A JP2007534308A5 JP 2007534308 A5 JP2007534308 A5 JP 2007534308A5 JP 2006541541 A JP2006541541 A JP 2006541541A JP 2006541541 A JP2006541541 A JP 2006541541A JP 2007534308 A5 JP2007534308 A5 JP 2007534308A5
- Authority
- JP
- Japan
- Prior art keywords
- photometrically
- labeled
- oligonucleotide
- labeling molecules
- labeling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000002372 labelling Methods 0.000 claims 6
- 108091034117 Oligonucleotide Proteins 0.000 claims 5
- 230000005284 excitation Effects 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52326303P | 2003-11-19 | 2003-11-19 | |
| PCT/US2004/038946 WO2005051967A2 (en) | 2003-11-19 | 2004-11-19 | Oligonucleotides labeled with a plurality of fluorophores |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011177659A Division JP5307206B2 (ja) | 2003-11-19 | 2011-08-15 | 複数のフルオロフォアで標識したオリゴヌクレオチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007534308A JP2007534308A (ja) | 2007-11-29 |
| JP2007534308A5 true JP2007534308A5 (https=) | 2011-10-06 |
Family
ID=34632765
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006541541A Withdrawn JP2007534308A (ja) | 2003-11-19 | 2004-11-19 | 複数のフルオロフォアで標識したオリゴヌクレオチド |
| JP2011177659A Expired - Fee Related JP5307206B2 (ja) | 2003-11-19 | 2011-08-15 | 複数のフルオロフォアで標識したオリゴヌクレオチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011177659A Expired - Fee Related JP5307206B2 (ja) | 2003-11-19 | 2011-08-15 | 複数のフルオロフォアで標識したオリゴヌクレオチド |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7667024B2 (https=) |
| EP (1) | EP1689764B1 (https=) |
| JP (2) | JP2007534308A (https=) |
| CN (1) | CN101076537B (https=) |
| WO (1) | WO2005051967A2 (https=) |
Families Citing this family (61)
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| EP2321429B1 (en) | 2008-09-03 | 2016-08-17 | Quantumdx Group Limited | Methods and kits for nucleic acid sequencing |
| US10759824B2 (en) | 2008-09-03 | 2020-09-01 | Quantumdx Group Limited | Design, synthesis and use of synthetic nucleotides comprising charge mass tags |
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| CN101709335B (zh) * | 2009-12-10 | 2011-12-21 | 浙江大学 | 一种人乳头瘤病毒常见型四重荧光定量pcr分型检测方法 |
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| DE102010003781B4 (de) | 2010-04-08 | 2012-08-16 | Aj Innuscreen Gmbh | Verfahren zum Nachweis spezifischer Nukleinsäuresequenzen |
| US9335289B2 (en) | 2011-02-07 | 2016-05-10 | The Governing Council Of The University Of Toronto | Bioprobes and methods of use thereof |
| EP2705160B1 (en) * | 2011-05-06 | 2018-08-22 | Qiagen GmbH | Nucleotides and oligonucleotides comprising a label associated through a linker |
| EP2782916B1 (en) | 2011-11-21 | 2018-02-28 | Promega Corporation | Carboxy x rhodamine analogs |
| CN114717296B (zh) | 2012-02-03 | 2025-04-04 | 加州理工学院 | 多路生化测定中信号的编码和解码 |
| EP3901243A1 (en) | 2012-08-03 | 2021-10-27 | California Institute of Technology | Multiplexing and quantification in pcr with reduced hardware and requirements |
| EP2943586B1 (en) | 2012-12-27 | 2017-09-20 | Seegene, Inc. | Detection of target nucleic acid sequence by pto cleavage and extension-dependent non-hybridization assay |
| US10077475B2 (en) | 2013-01-24 | 2018-09-18 | California Institute Of Technology | FRET-based analytes detection and related methods and systems |
| EP4570924A3 (en) * | 2013-01-24 | 2025-09-03 | California Institute of Technology | Chromophore-based characterization and detection methods |
| HK1218096A1 (zh) | 2013-03-15 | 2017-02-03 | Nanobiosym, Inc. | 用於移动设备分析核酸和蛋白质的系统和方法 |
| EP3019559A4 (en) | 2013-08-22 | 2017-04-05 | Sony Corporation | Water soluble fluorescent or colored dyes and methods for their use |
| WO2015061738A1 (en) * | 2013-10-25 | 2015-04-30 | Biomadison, Inc. | Enzyme assay with duplicate fluorophores |
| WO2015185564A1 (en) | 2014-06-02 | 2015-12-10 | Base4 Innovation Ltd | Nucleotide polymorphism detection method |
| WO2016081585A1 (en) * | 2014-11-20 | 2016-05-26 | Ampliwise Inc. | Compositions and methods for nucleic acid amplification |
| KR102646956B1 (ko) | 2015-02-26 | 2024-03-14 | 소니그룹주식회사 | 페닐에티닐나프탈렌 염료 및 이의 사용 방법 |
| US11827661B2 (en) | 2015-02-26 | 2023-11-28 | Sony Group Corporation | Water soluble fluorescent or colored dyes comprising conjugating groups |
| EP3400444A4 (en) | 2016-01-04 | 2019-10-16 | QuantuMDx Group Limited | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES WITH LOADING MASS MARKINGS |
| CN109415574B (zh) | 2016-04-01 | 2021-05-28 | 索尼公司 | 具有刚性间隔基团的超亮二聚体或聚合物染料 |
| AU2017240154B2 (en) | 2016-04-01 | 2021-08-12 | Sony Group Corporation | Ultra bright dimeric or polymeric dyes |
| WO2017177065A2 (en) | 2016-04-06 | 2017-10-12 | Sony Corporation | Ultra bright dimeric or polymeric dyes with spacing linker groups |
| EP3455299B1 (en) | 2016-05-10 | 2024-01-17 | Sony Group Corporation | Compositions comprising a polymeric dye and a cyclodextrin and uses thereof |
| JP7527537B2 (ja) | 2016-05-10 | 2024-08-05 | ソニーグループ株式会社 | ペプチド骨格を有する超明色ポリマー染料 |
| EP3455300A1 (en) | 2016-05-11 | 2019-03-20 | Sony Corporation | Ultra bright dimeric or polymeric dyes |
| EP3464477A1 (en) | 2016-06-06 | 2019-04-10 | Sony Corporation | Ionic polymers comprising fluorescent or colored reporter groups |
| US10066263B2 (en) | 2016-06-17 | 2018-09-04 | California Institute Of Technology | Nucleic acid reactions and related methods and compositions |
| JP7312929B2 (ja) | 2016-07-29 | 2023-07-24 | ソニーグループ株式会社 | 超明色二量体またはポリマー色素およびその調製のための方法 |
| KR20260011205A (ko) | 2017-10-05 | 2026-01-22 | 소니그룹주식회사 | 프로그램가능한 중합체성 약물 |
| WO2019071153A1 (en) | 2017-10-05 | 2019-04-11 | Sony Corporation | PROGRAMMABLE DENDRITIC MEDICINES |
| CN111836645A (zh) | 2017-11-16 | 2020-10-27 | 索尼公司 | 可编程的聚合药物 |
| EP3737417B1 (en) | 2018-01-12 | 2025-08-27 | Sony Group Corporation | Phosphoalkyl ribose polymers comprising biologically active compounds |
| US12539334B2 (en) | 2018-01-12 | 2026-02-03 | Sony Group Corporation | Phosphoalkyl polymers comprising biologically active agents |
| CN111565756A (zh) | 2018-01-12 | 2020-08-21 | 索尼公司 | 包含生物活性化合物的具有刚性间隔基团的聚合物 |
| KR102742386B1 (ko) | 2018-03-19 | 2024-12-16 | 소니그룹주식회사 | 형광 신호 향상을 위한 2가 금속의 사용 |
| CN118480073A (zh) | 2018-03-21 | 2024-08-13 | 索尼公司 | 具有连接体基团的聚合串联染料 |
| US12454720B2 (en) | 2018-04-17 | 2025-10-28 | ChromaCode, Inc. | Methods and systems for multiplex analysis |
| JP7580689B2 (ja) | 2018-06-27 | 2024-11-12 | ソニーグループ株式会社 | デオキシリボースを含むリンカー基を有するポリマー色素 |
| US12203129B2 (en) | 2018-07-03 | 2025-01-21 | ChromaCode, Inc. | Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays |
| KR20210032434A (ko) | 2018-07-13 | 2021-03-24 | 소니 주식회사 | 유기인산염 단위를 포함하는 백본을 갖는 중합체성 염료 |
| CA3105715A1 (en) | 2018-07-13 | 2020-01-16 | Quantum-Si Incorporated | Biconjugatable labels and methods of use |
| WO2020154546A1 (en) * | 2019-01-23 | 2020-07-30 | Quantum-Si Incorporated | High intensity labeled reactant compositions and methods for sequencing |
| WO2021004379A1 (zh) * | 2019-07-05 | 2021-01-14 | 南京金斯瑞生物科技有限公司 | 一种荧光标记核酸及其合成方法 |
| WO2021062176A2 (en) | 2019-09-26 | 2021-04-01 | Sony Corporation | Polymeric tandem dyes with linker groups |
| EP4038081A1 (en) * | 2019-09-30 | 2022-08-10 | Sony Group Corporation | Nucleotide probes |
| EP4256078A1 (en) | 2020-12-07 | 2023-10-11 | Sony Group Corporation | Spacing linker group design for brightness enhancement in dimeric or polymeric dyes |
| WO2023129887A1 (en) * | 2021-12-29 | 2023-07-06 | Co-Diagnostics, Inc. | Methods and systems for analyzing nucleic acids using increased ifret with multiple acceptor fluorophores |
| JP2023103945A (ja) * | 2022-01-14 | 2023-07-27 | 株式会社日立製作所 | 構造多型変異検出法 |
| US20230366038A1 (en) | 2022-05-16 | 2023-11-16 | Bioo Scientific Corporation | Compositions and methods relating to loop mediated isothermal amplification (lamp) |
| US12347527B2 (en) * | 2022-08-23 | 2025-07-01 | Leica Microsystems Cms Gmbh | Data storage device and method for storing data using an oligonucleotide nanostructure backbone and labels with dyes |
| WO2025207979A1 (en) * | 2024-03-27 | 2025-10-02 | 3D Medicines Biomedical Technologies, Inc. | Energy-transfer probes for multiplexed nucleic acid amplification assays |
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| US4766062A (en) | 1984-05-07 | 1988-08-23 | Allied Corporation | Displacement polynucleotide assay method and polynucleotide complex reagent therefor |
| US5118605A (en) * | 1984-10-16 | 1992-06-02 | Chiron Corporation | Polynucleotide determination with selectable cleavage sites |
| US5268486A (en) | 1986-04-18 | 1993-12-07 | Carnegie-Mellon Unversity | Method for labeling and detecting materials employing arylsulfonate cyanine dyes |
| US5118801A (en) | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US5654419A (en) * | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
| WO1997027317A1 (en) * | 1996-01-23 | 1997-07-31 | Affymetrix, Inc. | Nucleic acid analysis techniques |
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| AU693023B2 (en) * | 1995-05-05 | 1998-06-18 | Applied Biosystems, Llc | Methods and reagents for combined PCR amplification and hybridization probing assay |
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-
2004
- 2004-11-19 EP EP04811635A patent/EP1689764B1/en not_active Expired - Lifetime
- 2004-11-19 JP JP2006541541A patent/JP2007534308A/ja not_active Withdrawn
- 2004-11-19 WO PCT/US2004/038946 patent/WO2005051967A2/en not_active Ceased
- 2004-11-19 US US10/993,625 patent/US7667024B2/en not_active Expired - Fee Related
- 2004-11-19 CN CN200480040647.1A patent/CN101076537B/zh not_active Expired - Fee Related
-
2009
- 2009-12-23 US US12/646,514 patent/US20100240103A1/en not_active Abandoned
-
2011
- 2011-08-15 JP JP2011177659A patent/JP5307206B2/ja not_active Expired - Fee Related
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