JP2008532485A5 - - Google Patents
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- Publication number
- JP2008532485A5 JP2008532485A5 JP2007553214A JP2007553214A JP2008532485A5 JP 2008532485 A5 JP2008532485 A5 JP 2008532485A5 JP 2007553214 A JP2007553214 A JP 2007553214A JP 2007553214 A JP2007553214 A JP 2007553214A JP 2008532485 A5 JP2008532485 A5 JP 2008532485A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acids
- binding
- stranded dna
- nucleic acid
- binding reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004707 nucleic acids Proteins 0.000 claims 17
- 102000039446 nucleic acids Human genes 0.000 claims 17
- 150000007523 nucleic acids Chemical class 0.000 claims 17
- 239000003153 chemical reaction reagent Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 9
- 108020004414 DNA Proteins 0.000 claims 8
- 102000053602 DNA Human genes 0.000 claims 8
- 108020004682 Single-Stranded DNA Proteins 0.000 claims 4
- 230000003196 chaotropic effect Effects 0.000 claims 3
- 239000012266 salt solution Substances 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 230000008878 coupling Effects 0.000 claims 2
- 238000010168 coupling process Methods 0.000 claims 2
- 238000005859 coupling reaction Methods 0.000 claims 2
- 239000005357 flat glass Substances 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 238000005303 weighing Methods 0.000 claims 2
- PRDFBSVERLRRMY-UHFFFAOYSA-N 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole Chemical compound C1=CC(OCC)=CC=C1C1=NC2=CC=C(C=3NC4=CC(=CC=C4N=3)N3CCN(C)CC3)C=C2N1 PRDFBSVERLRRMY-UHFFFAOYSA-N 0.000 claims 1
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 claims 1
- 239000012625 DNA intercalator Substances 0.000 claims 1
- 239000012626 DNA minor groove binder Substances 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- INAAIJLSXJJHOZ-UHFFFAOYSA-N pibenzimol Chemical group C1CN(C)CCN1C1=CC=C(N=C(N2)C=3C=C4NC(=NC4=CC=3)C=3C=CC(O)=CC=3)C2=C1 INAAIJLSXJJHOZ-UHFFFAOYSA-N 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- ACOJCCLIDPZYJC-UHFFFAOYSA-M thiazole orange Chemical class CC1=CC=C(S([O-])(=O)=O)C=C1.C1=CC=C2C(C=C3N(C4=CC=CC=C4S3)C)=CC=[N+](C)C2=C1 ACOJCCLIDPZYJC-UHFFFAOYSA-M 0.000 claims 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical class [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/043,561 | 2005-01-26 | ||
| US11/043,561 US20060166223A1 (en) | 2005-01-26 | 2005-01-26 | DNA purification and analysis on nanoengineered surfaces |
| PCT/US2006/002708 WO2006081324A2 (en) | 2005-01-26 | 2006-01-25 | Dnd purification and analysis on nanoengineered surfaces |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008532485A JP2008532485A (ja) | 2008-08-21 |
| JP2008532485A5 true JP2008532485A5 (https=) | 2009-03-26 |
| JP5336087B2 JP5336087B2 (ja) | 2013-11-06 |
Family
ID=36697261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007553214A Expired - Fee Related JP5336087B2 (ja) | 2005-01-26 | 2006-01-25 | ナノ加工表面におけるｄｎａ浄化および分析 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20060166223A1 (https=) |
| EP (1) | EP1851337B1 (https=) |
| JP (1) | JP5336087B2 (https=) |
| KR (1) | KR20080047311A (https=) |
| CN (1) | CN101248187A (https=) |
| AU (1) | AU2006208078A1 (https=) |
| CA (1) | CA2595268A1 (https=) |
| ES (1) | ES2397352T3 (https=) |
| WO (1) | WO2006081324A2 (https=) |
Families Citing this family (53)
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| US20060166223A1 (en) * | 2005-01-26 | 2006-07-27 | Reed Michael W | DNA purification and analysis on nanoengineered surfaces |
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| CA2667631C (en) * | 2006-10-10 | 2017-11-07 | Miacom Diagnostics Gmbh | Nucleic acid beacons for fluorescent in-situ hybridisation and chip technology |
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| DE102008047790A1 (de) * | 2008-09-17 | 2010-04-15 | Qiagen Gmbh | Verfahren zur Normierung des Gehalts von Biomolekülen in einer Probe |
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| US9492797B2 (en) | 2008-09-23 | 2016-11-15 | Bio-Rad Laboratories, Inc. | System for detection of spaced droplets |
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| US9764322B2 (en) | 2008-09-23 | 2017-09-19 | Bio-Rad Laboratories, Inc. | System for generating droplets with pressure monitoring |
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| US9156010B2 (en) | 2008-09-23 | 2015-10-13 | Bio-Rad Laboratories, Inc. | Droplet-based assay system |
| US12162008B2 (en) | 2008-09-23 | 2024-12-10 | Bio-Rad Laboratories, Inc. | Partition-based method of analysis |
| US12090480B2 (en) | 2008-09-23 | 2024-09-17 | Bio-Rad Laboratories, Inc. | Partition-based method of analysis |
| US10512910B2 (en) | 2008-09-23 | 2019-12-24 | Bio-Rad Laboratories, Inc. | Droplet-based analysis method |
| WO2011120020A1 (en) | 2010-03-25 | 2011-09-29 | Quantalife, Inc. | Droplet transport system for detection |
| US11130128B2 (en) | 2008-09-23 | 2021-09-28 | Bio-Rad Laboratories, Inc. | Detection method for a target nucleic acid |
| EP4512526A3 (en) | 2008-09-23 | 2025-06-04 | Bio-Rad Laboratories, Inc. | Droplet-based assay system |
| US8663920B2 (en) | 2011-07-29 | 2014-03-04 | Bio-Rad Laboratories, Inc. | Library characterization by digital assay |
| US8633015B2 (en) * | 2008-09-23 | 2014-01-21 | Bio-Rad Laboratories, Inc. | Flow-based thermocycling system with thermoelectric cooler |
| US9417190B2 (en) | 2008-09-23 | 2016-08-16 | Bio-Rad Laboratories, Inc. | Calibrations and controls for droplet-based assays |
| US8709762B2 (en) | 2010-03-02 | 2014-04-29 | Bio-Rad Laboratories, Inc. | System for hot-start amplification via a multiple emulsion |
| KR20110101143A (ko) * | 2008-11-04 | 2011-09-15 | 블러드 셀 스토리지 인코퍼레이티드 | 굴곡 유리 표면 상에서의 핵산 추출 |
| DE112010002222B4 (de) | 2009-06-04 | 2024-01-25 | Leidos Innovations Technology, Inc. (n.d.Ges.d. Staates Delaware) | Mehr-Proben-Mikrofluidchip fur DNA-Analyse |
| EP2443254A2 (en) * | 2009-06-15 | 2012-04-25 | NetBio, Inc. | Improved methods for forensic dna quantitation |
| CA2767056C (en) * | 2009-09-02 | 2018-12-04 | Bio-Rad Laboratories, Inc. | System for mixing fluids by coalescence of multiple emulsions |
| US8399198B2 (en) | 2010-03-02 | 2013-03-19 | Bio-Rad Laboratories, Inc. | Assays with droplets transformed into capsules |
| CA2767182C (en) | 2010-03-25 | 2020-03-24 | Bio-Rad Laboratories, Inc. | Droplet generation for droplet-based assays |
| JP2013524169A (ja) | 2010-03-25 | 2013-06-17 | クァンタライフ・インコーポレーテッド | 液滴によるアッセイ用の検出システム |
| GB2497501A (en) | 2010-10-15 | 2013-06-12 | Lockheed Corp | Micro fluidic optic design |
| EP3574990B1 (en) | 2010-11-01 | 2022-04-06 | Bio-Rad Laboratories, Inc. | System for forming emulsions |
| US12097495B2 (en) | 2011-02-18 | 2024-09-24 | Bio-Rad Laboratories, Inc. | Methods and compositions for detecting genetic material |
| CN103534360A (zh) | 2011-03-18 | 2014-01-22 | 伯乐生命医学产品有限公司 | 借助对信号的组合使用进行的多重数字分析 |
| EP3395957B1 (en) | 2011-04-25 | 2020-08-12 | Bio-Rad Laboratories, Inc. | Methods and compositions for nucleic acid analysis |
| US8629264B2 (en) | 2011-05-19 | 2014-01-14 | Blood Cell Storage, Inc. | Gravity flow fluidic device for nucleic acid extraction |
| WO2013016321A1 (en) | 2011-07-26 | 2013-01-31 | Elitech Holding B.V. | Minor groove binder phosphoramidites and methods of use |
| JP2013117424A (ja) * | 2011-12-02 | 2013-06-13 | Enplas Corp | 流体取扱装置 |
| US9322054B2 (en) | 2012-02-22 | 2016-04-26 | Lockheed Martin Corporation | Microfluidic cartridge |
| ES2528491B1 (es) * | 2013-06-20 | 2020-02-27 | Consejo Superior Investigacion | Dispositivo para la deteccion de una unica molecula en situacion de nanoconfinamiento y en regimen dinamico, procedimiento de fabricacion y uso |
| WO2017059477A1 (en) | 2015-10-07 | 2017-04-13 | Sangui Bio Pty. Ltd | Blood preparation and profiling |
| CA3009369A1 (en) | 2015-12-22 | 2017-06-29 | Sangui Bio Pty. Ltd | Therapeutic methods using erythrocytes |
| EP3475443B1 (en) * | 2016-06-23 | 2025-02-12 | Life Technologies Corporation | Methods and compositions for detecting or measuring caspases or apoptosis |
| CN110366597B (zh) | 2016-12-20 | 2024-03-29 | 善威生物私人有限公司 | 用蛋白酶抑制剂进行血液图谱分析 |
| US20210263028A1 (en) * | 2018-09-19 | 2021-08-26 | Lumiradx Uk Ltd. | Assay |
| CN111349555B (zh) * | 2018-12-21 | 2023-07-18 | 成都万众壹芯生物科技有限公司 | 一种基于微孔阵列芯片的数字pcr扩增装置及其使用方法 |
| CN111635945B (zh) * | 2020-07-07 | 2023-09-19 | 益善生物技术股份有限公司 | 一种Vimentin基因表达检测试剂盒 |
| CN114295594B (zh) * | 2021-12-06 | 2023-09-19 | 贵州理工学院 | 一种基于分子信标筛选三螺旋DNA嵌入剂的“turn on”型荧光传感器 |
| AU2023263416A1 (en) | 2022-04-29 | 2024-11-07 | Cepheid | Nucleic acid extraction and isolation with heat labile silanes and chemically modified solid supports |
Family Cites Families (58)
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| US4883867A (en) * | 1985-11-01 | 1989-11-28 | Becton, Dickinson And Company | Detection of reticulocytes, RNA or DNA |
| US6147198A (en) * | 1988-09-15 | 2000-11-14 | New York University | Methods and compositions for the manipulation and characterization of individual nucleic acid molecules |
| US6150089A (en) * | 1988-09-15 | 2000-11-21 | New York University | Method and characterizing polymer molecules or the like |
| US5720928A (en) * | 1988-09-15 | 1998-02-24 | New York University | Image processing and analysis of individual nucleic acid molecules |
| JPH02176457A (ja) * | 1988-09-15 | 1990-07-09 | Carnegie Inst Of Washington | パルス志向電気泳動 |
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-
2005
- 2005-01-26 US US11/043,561 patent/US20060166223A1/en not_active Abandoned
-
2006
- 2006-01-25 CA CA002595268A patent/CA2595268A1/en not_active Abandoned
- 2006-01-25 JP JP2007553214A patent/JP5336087B2/ja not_active Expired - Fee Related
- 2006-01-25 KR KR1020077019455A patent/KR20080047311A/ko not_active Abandoned
- 2006-01-25 EP EP06719536A patent/EP1851337B1/en not_active Expired - Lifetime
- 2006-01-25 AU AU2006208078A patent/AU2006208078A1/en not_active Abandoned
- 2006-01-25 CN CNA2006800097994A patent/CN101248187A/zh active Pending
- 2006-01-25 ES ES06719536T patent/ES2397352T3/es not_active Expired - Lifetime
- 2006-01-25 WO PCT/US2006/002708 patent/WO2006081324A2/en not_active Ceased
-
2007
- 2007-07-24 US US11/880,790 patent/US20090029867A1/en not_active Abandoned
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