JP2007532666A5 - - Google Patents
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- Publication number
- JP2007532666A5 JP2007532666A5 JP2007508498A JP2007508498A JP2007532666A5 JP 2007532666 A5 JP2007532666 A5 JP 2007532666A5 JP 2007508498 A JP2007508498 A JP 2007508498A JP 2007508498 A JP2007508498 A JP 2007508498A JP 2007532666 A5 JP2007532666 A5 JP 2007532666A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antiviral composition
- group
- nuclease
- gly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56193404P | 2004-04-14 | 2004-04-14 | |
| PCT/US2005/012532 WO2005115444A2 (en) | 2004-04-14 | 2005-04-14 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007532666A JP2007532666A (ja) | 2007-11-15 |
| JP2007532666A5 true JP2007532666A5 (enExample) | 2008-07-03 |
Family
ID=35451407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007508498A Pending JP2007532666A (ja) | 2004-04-14 | 2005-04-14 | ウイルス核酸を対象とした修飾ヌクレアーゼを用いた組成物及びウイルス性疾患の予防並びに治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9592277B2 (enExample) |
| EP (1) | EP1734991A4 (enExample) |
| JP (1) | JP2007532666A (enExample) |
| AU (2) | AU2005247298B8 (enExample) |
| CA (1) | CA2604243C (enExample) |
| IL (1) | IL178802A0 (enExample) |
| WO (1) | WO2005115444A2 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9248166B2 (en) | 2003-07-14 | 2016-02-02 | Cls Therapeutics Limited | Method for treating oncological diseases |
| US8710012B2 (en) | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
| US8388951B2 (en) | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
| US8431123B2 (en) | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
| US9592277B2 (en) * | 2004-04-14 | 2017-03-14 | Avirid, Inc. | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases |
| EP1880733A4 (en) | 2005-04-25 | 2009-08-12 | Genkin Dmitry Dmitrievich | Method for increasing longevity of a human being and animals |
| WO2007133812A2 (en) * | 2005-12-30 | 2007-11-22 | Philadelphia Health & Education Corporation, D/B/A Drexel University College Of Medicine | Improved carriers for delivery of nucleic acid agents to cells and tissues |
| WO2007091958A1 (en) * | 2006-02-10 | 2007-08-16 | Dermagen Ab | Novel antimicrobial peptides and use thereof |
| US8840882B2 (en) * | 2006-06-23 | 2014-09-23 | Quintessence Biosciences, Inc. | Modified ribonucleases |
| MX2009002856A (es) * | 2006-09-15 | 2009-03-30 | Enzon Pharmaceuticals Inc | Conjugados polimericos que contienen porciones cargadas positivamente. |
| KR20090087095A (ko) * | 2006-11-28 | 2009-08-14 | 드미트리 드미트리에비치 겐킨 | 조직의 세포외공간에서 증가된 데옥시리보핵산 함량과 관련된 인간 질병을 치료하는 방법 및 이 방법을 수행하기 위한 약학 제제 |
| US9296790B2 (en) | 2008-10-03 | 2016-03-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for protein delivery |
| WO2011031467A1 (en) * | 2009-08-25 | 2011-03-17 | Wayne State University | Anti-cancer therapeutic strategy to overcome cancer resistance and to enable tailoring treatment to patients |
| GB0922066D0 (en) | 2009-12-17 | 2010-02-03 | Univ Belfast | Modulator |
| CN102811746A (zh) * | 2010-01-18 | 2012-12-05 | 得克萨斯系统大学评议会 | 用于纳米颗粒介导的癌细胞靶向递送的方法和组合物 |
| KR101341640B1 (ko) * | 2010-02-05 | 2013-12-16 | 한국전자통신연구원 | 단백질 미세 구조 분석 방법 및 단백질 미세 구조 분석용 어레이 |
| US8981044B2 (en) | 2010-04-21 | 2015-03-17 | National University Corporation Hokkaido University | Lipid membrane structure having intranuclear migrating property |
| EP2490021A1 (en) | 2011-02-18 | 2012-08-22 | Biotempt B.V. | Modulators of PRR and GPCR signalling |
| WO2013126872A1 (en) * | 2012-02-24 | 2013-08-29 | Wayne State University | Anti-cancer therapeutic strategy to overcome cancer resistance and to enable tailoring treatment to patients |
| EP3663395B1 (en) | 2012-03-26 | 2024-07-31 | The United States of America, as Represented by The Secretary, Department of Health and Human Services Office of Technology, Transfer, | Delivery of packaged rna to mammalian cells |
| EP3919505B1 (en) | 2013-01-16 | 2023-08-30 | Emory University | Uses of cas9-nucleic acid complexes |
| US20160038528A1 (en) * | 2013-03-15 | 2016-02-11 | Techulon Inc. | Rapidly Adaptable Nano Therapeutics for Treatment of Infectious Disease |
| US11306326B2 (en) | 2013-08-23 | 2022-04-19 | Rutgers, The State University Of New Jersey | Biologically active synthetic nanoparticle constructs and methods of use thereof |
| EP3035917A4 (en) * | 2013-08-23 | 2017-03-01 | Rutgers, the State University of New Jersey | Biologically active synthetic nanoparticle constructs and methods of use therof |
| KR102467982B1 (ko) | 2013-12-16 | 2022-11-16 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | Vlp-레플리콘을 이용한 클래스 ii mhc 항원의 전달에 의한 암 면역요법 |
| US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
| CN107002091A (zh) * | 2014-10-01 | 2017-08-01 | 植物保健公司 | 过敏反应激发子肽及其用途 |
| US10743538B2 (en) | 2014-10-01 | 2020-08-18 | Plant Health Care, Inc. | Elicitor peptides having disrupted hypersensitive response box and use thereof |
| RU2726131C2 (ru) | 2015-05-22 | 2020-07-09 | Дмитрий Дмитриевич Генкин | Внеклеточная днк в качестве терапевтической мишени при нейродегенерации |
| US10117911B2 (en) | 2015-05-29 | 2018-11-06 | Agenovir Corporation | Compositions and methods to treat herpes simplex virus infections |
| JP7341451B2 (ja) | 2016-02-01 | 2023-09-11 | エピアクシス セラピューティクス プロプライアタリー リミティド | タンパク質性化合物とその利用 |
| CA3082055A1 (en) | 2017-11-08 | 2019-05-16 | Epiaxis Therapeutics Pty Ltd | Immunogenic compositions and uses therefor |
| WO2019099685A1 (en) | 2017-11-15 | 2019-05-23 | Rutgers, The State University Of New Jersey | Biodegradable hybrid inorganic nanoscaffolding materials and methods of use and manufacture thereof |
| JP7398115B2 (ja) | 2017-12-22 | 2023-12-14 | ノース カロライナ ステート ユニバーシティ | ポリマーフルオロフォア、それを含む組成物、ならびにその調製および使用方法 |
| US11905522B2 (en) | 2018-01-16 | 2024-02-20 | Cls Therapeutics Limited | Treatment of diseases by liver expression of an enzyme which has a deoxyribonuclease (DNase) activity |
| JP7384906B2 (ja) * | 2018-07-09 | 2023-11-21 | ジーアールオー・バイオサイエンシズ・インコーポレイテッド | 非標準アミノ酸含有組成物とその使用 |
| WO2020106709A1 (en) * | 2018-11-19 | 2020-05-28 | Gro Biosciences Inc. | Human dnase for lung disease |
| KR102921733B1 (ko) * | 2019-01-28 | 2026-02-03 | 마이크로벤션, 인코포레이티드 | 코팅 |
| EP3952919A2 (en) * | 2019-04-11 | 2022-02-16 | Northeastern University | Oligonucleotide-polymer miktoarm conjugates and methods of use |
| WO2021046307A1 (en) * | 2019-09-04 | 2021-03-11 | North Carolina State University | Hybridized poly(amidoamine)-amino acid dendrimers |
| TW202146053A (zh) * | 2020-01-24 | 2021-12-16 | 美商薩羅塔治療公司 | 藉由可解釋機器學習設計反義寡核苷酸遞送肽 |
| EP4149443A4 (en) * | 2020-05-11 | 2024-05-29 | Revir, Inc. | Compositions and methods for treating viral infections |
| US11331329B2 (en) | 2020-05-13 | 2022-05-17 | Glycosyn LLC | Fucosylated oligosaccharides for prevention of coronavirus infection |
| US11324766B2 (en) * | 2020-05-13 | 2022-05-10 | Glycosyn LLC | 2'-fucosyllactose for the prevention and treatment of coronavirus-induced inflammation |
| US11883564B2 (en) | 2020-07-30 | 2024-01-30 | Microvention, Inc. | Antimicrobial coatings |
| US20220040315A1 (en) * | 2020-08-09 | 2022-02-10 | Fulu Labs Corporation | Nuclease-dendrimer formulations for covid-19 and broad-spectrum antiviral therapy and prophylaxis |
| WO2022040761A1 (en) * | 2020-08-31 | 2022-03-03 | Starpharma Pty Ltd | Dendrimer-drug conjugate |
| CN117651550A (zh) * | 2021-07-02 | 2024-03-05 | 奥古尔·米尔扎尤索夫娜·穆萨哈诺娃 | 用于预防SARS-CoV-2感染的药物 |
| CN114250208B (zh) * | 2021-12-22 | 2023-07-25 | 武汉瀚海新酶生物科技有限公司 | 耐高盐高活性DNase I突变体的制备及应用 |
| WO2024092230A2 (en) * | 2022-10-28 | 2024-05-02 | The Regents Of The University Of California | Recombinant enhanced antiviral restrictors |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5115096A (en) * | 1988-04-15 | 1992-05-19 | Oncogen | Amphiregulin: a bifunctional growth modulating glycoprotein |
| WO1990010015A1 (en) * | 1989-02-23 | 1990-09-07 | Seragen, Inc. | Chimeric toxin |
| US5629173A (en) * | 1990-08-09 | 1997-05-13 | Genentech, Inc. | Methods of use of serine protease variants having peptide ligase activity |
| US5989886A (en) * | 1991-01-02 | 1999-11-23 | The Johns Hopkins University | Method for the inhibition and prevention of viral replication using fusions of a virus protein and a destructive enzyme |
| US5792640A (en) * | 1992-04-03 | 1998-08-11 | The Johns Hopkins University | General method to clone hybrid restriction endonucleases using lig gene |
| US5484589A (en) * | 1992-04-20 | 1996-01-16 | Rufeld, Inc. | Anti-viral methods using RNAse and DNAse |
| US5503973A (en) | 1992-05-29 | 1996-04-02 | The Regents Of The University Of California | Method for inhibition of viral morphogenesis |
| WO1995000170A1 (en) | 1993-06-24 | 1995-01-05 | Rufeld, Inc. | Inhibition of human immunodeficiency virus reproduction by deoxyribonuclease i |
| RU2066551C1 (ru) * | 1994-03-23 | 1996-09-20 | Институт нефтехимического синтеза РАН | Способ получения инсулинсодержащих полимерных гидрогелей |
| US20030053982A1 (en) * | 1994-09-26 | 2003-03-20 | Kinstler Olaf B. | N-terminally chemically modified protein compositions and methods |
| US5997861A (en) * | 1994-10-31 | 1999-12-07 | Burstein Laboratories, Inc. | Antiviral supramolecules containing target-binding molecules and therapeutic molecules bound to spectrin |
| US6348343B2 (en) * | 1995-02-24 | 2002-02-19 | Genentech, Inc. | Human DNase I variants |
| US5690942A (en) * | 1995-06-02 | 1997-11-25 | American Home Products Corporation | Adjuvants for viral vaccines |
| US7432048B2 (en) * | 1996-11-29 | 2008-10-07 | Third Wave Technologies, Inc. | Reactions on a solid surface |
| US5739512A (en) | 1996-05-30 | 1998-04-14 | Sun Microsystems, Inc. | Digital delivery of receipts |
| US6391607B1 (en) * | 1996-06-14 | 2002-05-21 | Genentech, Inc. | Human DNase I hyperactive variants |
| US6214966B1 (en) * | 1996-09-26 | 2001-04-10 | Shearwater Corporation | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution |
| US6280991B1 (en) * | 1997-10-15 | 2001-08-28 | Wisconsin Alumni Research Foundation | Engineered cytotoxic ribonclease |
| US6017537A (en) * | 1998-12-18 | 2000-01-25 | Connaught Laboratories, Inc. | Formyl methionyl peptide vaccine adjuvant |
| DE69941223D1 (de) * | 1998-12-21 | 2009-09-17 | Billig Fritz | Chemisch modifizierte enzymen mit mehrfachgeladenen varianten |
| US6485718B1 (en) * | 1999-04-13 | 2002-11-26 | Pharmacia Corporation | Site specific ligation of proteins to synthetic particles |
| KR100642955B1 (ko) * | 1999-04-23 | 2006-11-10 | 알자 코포레이션 | 방출성 결합 및 그를 함유하는 조성물 |
| MXPA02001857A (es) * | 1999-08-24 | 2003-07-14 | Cellgate Inc | Composiciones y metodos para incrementar la entrega de drogas a traves y dentro de tejidos epiteliales. |
| US6669951B2 (en) * | 1999-08-24 | 2003-12-30 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into epithelial tissues |
| US20010053521A1 (en) * | 1999-09-27 | 2001-12-20 | Kreimer David I. | Amplification of analyte detection by substrates having particle structures with receptors |
| US6312956B1 (en) * | 1999-10-01 | 2001-11-06 | Vanderbilt University | Nuclear targeted peptide nucleic acid oligomer |
| US6962906B2 (en) * | 2000-03-14 | 2005-11-08 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
| EP1274720A4 (en) * | 2000-04-12 | 2004-08-18 | Human Genome Sciences Inc | FUSION PROTEINS CONTAINING ALBUMIN |
| US7091026B2 (en) * | 2001-02-16 | 2006-08-15 | University Of Iowa Research Foundation | Artificial endonuclease |
| WO2002094250A2 (en) * | 2001-05-18 | 2002-11-28 | Cureon A/S | Therapeutic uses of lna-modified oligonucleotides in infectious diseases |
| US6913903B2 (en) * | 2001-09-07 | 2005-07-05 | Nobex Corporation | Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
| GB0126251D0 (en) | 2001-11-01 | 2002-01-02 | Imp College Innovations Ltd | Methods |
| JP2005538186A (ja) | 2002-09-13 | 2005-12-15 | レプリコール インコーポレーティッド | 非配列相補性の抗ウイルス性オリゴヌクレオチド |
| US20040147027A1 (en) * | 2003-01-28 | 2004-07-29 | Troy Carol M. | Complex for facilitating delivery of dsRNA into a cell and uses thereof |
| JP2008505853A (ja) * | 2004-04-13 | 2008-02-28 | クインテセンス バイオサイエンシーズ インコーポレーティッド | 細胞傷害性薬剤としての非天然のリボヌクレアーゼ複合体 |
| US9592277B2 (en) * | 2004-04-14 | 2017-03-14 | Avirid, Inc. | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases |
-
2005
- 2005-04-14 US US11/578,716 patent/US9592277B2/en active Active - Reinstated
- 2005-04-14 EP EP05780021A patent/EP1734991A4/en not_active Withdrawn
- 2005-04-14 WO PCT/US2005/012532 patent/WO2005115444A2/en not_active Ceased
- 2005-04-14 JP JP2007508498A patent/JP2007532666A/ja active Pending
- 2005-04-14 CA CA2604243A patent/CA2604243C/en not_active Expired - Lifetime
- 2005-04-14 AU AU2005247298A patent/AU2005247298B8/en not_active Ceased
-
2006
- 2006-10-22 IL IL178802A patent/IL178802A0/en unknown
-
2011
- 2011-02-11 AU AU2011200602A patent/AU2011200602A1/en not_active Abandoned
-
2017
- 2017-03-10 US US15/455,574 patent/US10335372B2/en not_active Expired - Lifetime
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